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At least 613 records · Page 34Linked to original sources
PubMed2005

[Use of essentiale and cholagogum in prevention of cholelithiasis in fat hepatosis with concomitant cholecystitis].

AIM: To assess efficacy of essentiale in combination with cholagogum in prevention of cholelithogenesis in patients with fat hepatosis (FH) and concomitant cholecystitis (CC). MATERIAL AND METHODS: 100 patients aged 31-60 years with FH and CC were examined using clinical, device and biochemical tests. The diagnosis was verified by the results of ultrasonography, computed and MR tomography. Fractionated duodenal tubing followed by biochemical examination of bile was conducted in all the patients. RESULTS: Changes in physico-chemical properties of hepatic and vesical bile corresponding to stage I of cholelithiasis occurred in most of the examinees. Treatment with essentiale +cholagogum is clinically effective, improves functional condition of bile ducts and the liver, diminishes bile lithogenicity. CONCLUSION: In fat hepatosis and concomitant cholecystitis, essentiale and cholagogum improve biochemical composition of bile, resulting finally in decreased risk of cholelithogenesis.

Adult↗
PubMedDate not supplied

Aspects of the humoral and cellular immune response in hepatitis associated with cholelithiasis.

AIM: To investigate the immunological reactions of the liver in various gall bladder disease. METHODS: IgG, IgA and IgM were measured in the blood and bile of patients with cholecystectomy. Immunofluorescence and electron microscopy techniques were used. RESULTS: The tests showed high blood values of immunoglobulins and their presence in the bile. The immunofluorescence was positive for IgG in the hepatic sinusoids. The electron microscopy showed aspects of "cellular cooperation". CONCLUSIONS: On the basis of our results we can affirm that in cholelithiasis there exists an immune response to the persistent antigens, with the release of circulating immune complexes.

Bile↗
PubMed2005

[Insulin resistance in patients with metabolic syndrome and cholelithiasis].

The aim of the study was to determine serum insulin level in patients with metabolic syndrome (MS), pronounced manifestation of cholelithiasis (CL), and abdominal obesity. The measurements were compared with hyperlipidemia and glycemia levels in these patients. The subjects were 55 women with MS, divided into two groups according to 1991 Kh. Kh. Mansurov's classification of CL stages. Insulin level was measured by immune-enzyme assay; carbohydrate and lipid metabolism (lipid levels, lipoprotein and fatty acid spectrums, malonic dialdehyde and catalase levels)--by conventional methods. The study revealed a correlation between high insulin level in patients with hyperglycemia, disorder of tolerance to glucose, and type II diabetes, on the one hand, and lipid peroxidation level and dislipidemia, on the other. The study also found high insulin level at various stages of CL, especially during the period of concrement formation. Insulin is a CL risk factor, i.e. it elevates the risk of nucleation.

Adult↗
PubMed1991

[Surgical treatment of cholelithiasis in children with sickle-cell anemia].

From 1979 to 1990 37 children with sickle cell disease underwent surgery for cholelithiasis. Mean age was 11,3 years. Twenty-four children had a history of recurrent abdominal pain; 8 of them were admitted for an acute gallstone complication. In 9 cases the stones were detected by systematic echography. The incidence of gallstones increasing with age, the rate of complications, the frequent resolution of recurrent abdominal pain after cholecystectomy justify elective surgery at the time of diagnostic of the stones. A transfusion preparation considerably reduces the risk of post-operative complications.

Abdominal Pain↗
PubMed2006

[One-stage combined operations in cholelithiasis].

Immediate results of one-stage combined operations in 509 patients aged 16 to 90 years with cholelithiasis performed in 1981-2005 were analyzed. Main indications for one-stage combined operations in these patients in urgent and elective surgery are listed. The operation was elective in 457 (89.8%) cases and urgent -- in 52 (10.2%). Laparotomy and cholecystectomy with hernioplasty were performed in 180 (35.4%) patients, resection of the stomach in patients with duodenal and gastric ulcer -- in 89 (17.5%), extirpation of the stomach for cancer -- in 89 (17.5%) patients. Retroperitoneal surgeries were performed in 13 (2.6%) patients. The operations were performed under general anesthesia in all the 509 patients. Postoperative lethality was 0.8% (4 patients).

Aged↗
PubMed2006

[Simultaneous operations through mini-approach in patients with multifocal atherosclerosis and cholelithiasis].

The experience with simultaneous operations in 16 patients with multifocal atherosclerosis and cholelithiasis is analyzed. The operations were performed simultaneously through two mini-approaches with original "mini-assistant" devices. Short- and long-term postoperative results are analyzed, indications and surgical techniques through mini-approach in elderly patients are reported.

Aged↗
PubMed2006

Treatment of cholelithiasis by acupuncture and oral decoction.

Thirty-six cases of cholelithiasis were treated by acupuncture at the Back-Shu and Front-Mu points plus oral decoction. The total effective rate was 97.2%, and the cured plus markedly effective rate was 83.3%, which were much better than those of 83.3% and 52.8% in the control group of 36 cases treated with oral decoction alone. The statistical differences between the two groups were respectively P < 0.05 and P < 0.01.

Acupuncture Points↗
PubMed2006

Obstructive cholelithiasis and cholecystitis in a keeshond.

A 10-year-old, neutered male, keeshond was presented for vomiting, lethargy, icterus, and anorexia. Obstructive cholelithiasis was diagnosed based on analysis of a serum biochemical profile, abdominal radiographs, and ultrasonography. Choleliths were removed from the gall bladder and common bile duct via a cholecystotomy.

Animals↗
PubMed2006

[Clinical observation on frequency-changeable electroacupuncture for treatment of cholelithiasis].

OBJECTIVE: To search for an effective, safe, practical therapy for removing cholelithiasis in biliary tract. METHODS: One hundred and twenty cases were randomly divided into a treatment group and a control group. The treatment group were treated with frequency-changeable electroacupuncture at Qimen (LR 14), Liangmen (ST 21), Riyue (GB 24), Danshu (BL 19), Ganshu (BL 18), Yanglingquan (GB 34), and Dannang (EX-LE6), and the control group with Chinese medicine Paishi Decoction, 40 mL of 33% magnesium sulfate, 30 mL of 0.5% hydrochloric acid and fat diet, and with a Tuian Yunjing Instrument. Their therapeutic effects were observed. RESULTS: The total effective rate was 86.7% in the treatment group and 68.3% in the control group with a significant difference between the two groups (P < 0.05). CONCLUSION: The frequency-changeable electroacupuncture has a definite therapeutic effect on the gallstone which is better than the comprehensive lithagogue therapy.

Adult↗
PubMedDate not supplied

[Effect of a carnitine analog on the level of bile lipids of the enterohepatic system in rabbits in cholelithiasis].

Lipid components were studied in enterohepatic system of rabbits with cholelithiasis after administration of plant components contained in meadow hay as well as of their mixture with a synthetic analogue of carnitine. Hypothetic mechanism of the carnitine derivative effect, contributing to elevation of phosphatidyl choline production in hepatocytes and to accumulation of the phospholipid in bile, is discussed. During the treatment course the calculous form of hepatocholecystitis was not detected in the experimental animals.

Animals↗
PubMed1991

[Cholelithiasis in congenital cysts of the hepatic ducts].

The article describes two cases (0.04%) of congenital cystic cholangiectasia complicated by cholelithiasis, which was revealed among 4,800 patients who underwent operation on the biliary tract. The disease was recognized during surgical intervention, retrograde cholangiopancreatography, and computed tomography. The authors carried out hepatoenterostomy with the use of a loop of the small intestine excluded after Roux and formation of choledochoduodenal anastomosis. Biliodigestive anastomoses create good conditions for the passage of bile and concrements from the ducts.

Bile Duct Diseases↗
PubMed1976

The process of cholesterol cholelithiasis induced by diet in the prairie dog: a physicochemical characterization.

The rapid induction of cholesterol cholelithiasis in a new experimental model, the prairie dog, has recently been reported by two groups. In this model they were able to induce gallstones in as brief a period as 2 weeks, using a 1.2 per cent cholesterol diet. This unprecedented time intensity or telescoping of the induction process provided a unique opportunity for observation of physicochemical changes occurring rapidly over a short period of time and to correlate these with degree of biliary cholesterol saturation. To make such observations, 97 adult male and female prairie dogs were used in the present study. Seventy-two were fed the high cholesterol diet and sacrificed at intervals over a 14-day period; the remaining 25 were used as controls. The primary objective of this work was to determine whether or not there was any relationship between the in vivo events induced in prairie dog bile and our recently reported detailed observations of cholesterol precipitation phenomena in synthetic bile analogs. In these studies, solutions of physiologically relevant composition were constructed, which, when plotted according to convention on a tri-linear graph, fell within the zone of metastable or suspended supersaturation. These solutions revealed a consistent and previously undescribed liquid crystal to solid crystal phase transition during their approach to equilibrium at 37 degrees C. The in vivo studies of prairie dog bile following rapid induction of supersaturation revealed identical changes. At first, the supersaturated biles were isotropic followed by a period of turbidity and invariable formation of mesophase. After a few days, the liquid crystals decreased and solid cholesterol crystallites appeared. The most striking aspect of these observations is that the in vitro work has now predicted not only static, but dynamic processes as well, with respect to cholesterol precipitation beginning with the metastably supersaturated state and eventuating in gallstone formation. Ancillary new findings, resulting from the high cholesterol diet, included the induction of human-like hyper-beta-lipoproteinemia and rapid hepatocyte degranulation shown by electron microscopy.

Animals↗
PubMed1991

[The characteristics of the course of Yersinia hepatitis in cholelithiasis patients].

The paper is concerned with a clinical description of yersiniosis in 12 women who suffered from manifest or uneventful cholelithiasis. The disease started by an attack of biliary colic. The clinical symptomatology was noticed to run in stages during which the signs of calculous cholecystitis vanished while the symptoms of hepatitis persisted. In the acute period, the conservative treatment of the patients was carried out by the infectionist jointly with the surgeon, followed by dispensary observation lasting 1 to 3 months until complete and stable normalization of aminotranferase activity. The outcomes were favourable.

Acute Disease↗
PubMedDate not supplied

[Cholelithiasis in young individuals].

It is presented a retrospective study of 20 patients under 30 years of age that underwent surgery for cholelithiasis in the "Hospital Ipiranga-INAMPS", São Paulo, from 1987 to 1990. The incidence in this group was 6.8% with sex distribution higher in the female. Only one patient had associated hemolytic disease (5%). The clinical findings were not different in this population and the diagnosis prior to surgery was possible in all cases. The high incidence found for acute cholecystitis (45%) and calculi migration (20%) should emphasize the importance of diagnostic and therapeutic approach in the young patient.

Adolescent↗
PubMed1991

Mucin-producing cells and endocrine cells of gallbladder epithelium in patients with uncomplicated cholelithiasis.

In this study we have investigated various morphofunctional features of gallbladder mucosa in patients with uncomplicated cholelithiasis. The histological changes, endocrine cell types and their distribution, and mucin-producing cells were characterized by immunocytochemistry and mucin histochemistry; moreover, we attempted to correlate these findings to the number and size of gallbladder stones and the type of bacteria present in the bile. Our results indicate that, despite similar clinical parameters, a wide range of histological changes can occur in the gallbladder mucosa of these patients. Moreover, the presence of certain endocrine and mucin-producing cell types in so-called "pyloric metaplasia" led us to hypothesize that this finding may be a trivial event in the gallbladder epithelium.

Cholelithiasis↗
PubMed1991

1291 cases of cholelithiasis treated with electric shock on otoacupoints.

Since 1985, the authors began to use electric shock on otoacupoints of varying electric resistance for the treatment of cholelithiasis. The instrument used was the Channel Therapeutic Instrument made in China, and the otoacupoints of varying electric resistance were Sympathetic, Pancreas--Gall Bladder, Stomach, Liver, Sanjiao, Endocrine, and Ermigen. In the 1291 cases treated, the total effective rate was 99.69%, the rate of calculus excretion was 91.32%, and the rate of total excretion was 19.51%. The composition of the calculi was cholesterol crystals (31.25%), bilirubin crystals (28.17%), and mixed crystals (40.58%). The largest calculus excreted was an extrahepatic biliary duct calculus of 1.75 cm X 1.5 cm; the largest number of calculi excreted was 152 cholecystic stones 0.3 cm X 0.5 cm in size. In 100 random cases, the biliary system was shown to manifest vigorous dilations and constrictions under Ultrasonic B-scan when the relevant otoacupoints were stimulated with electric shock. Among the 78 control cases, no cholecystic stones were excreted, inspite of the Magnesium Sulfate, Folium Cassiae and fatty meals administered to many cases with constipation.

Acupuncture Points↗