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At least 613 records · Page 34Linked to original sources
PubMed1984

Bilateral tension pneumothorax during pediatric bronchoscopy (high-frequency jet injection ventilation).

Bilateral tension pneumothorax complicating high-frequency jet injection ventilation during rigid open bronchoscopy for foreign body removal in a 3-year-old child is reported. Subcutaneous emphysema, bradycardia and low voltage of the QRS complex were the presenting symptoms. Disparition of heart dullness by percussion was the most suggestive clinical sign while auscultation of the breath sounds was not conclusive. It is stressed that tension pneumothorax is a potential life-threatening complication of high-frequency injection ventilation and should be promptly considered in any case of persistent cardiac deterioration during pediatric bronchoscopy.

Airway Obstruction↗
PubMed1999

Detection of bronchial preneoplastic lesions and early lung cancer with fluorescence bronchoscopy: a study about its ambulatory feasibility under local anaesthesis.

BACKGROUND: Autofluorescence bronchoscopy (AB) enhances the bronchoscopist's ability to diagnose bronchial preneoplastic lesions and early cancer. We undertook a study to assess its feasibility and performance under local anaesthesia on a real ambulatory mode. METHODS: Thirty-four consecutive patients at very high risk for lung cancer were prospectively studied by AB under local anaesthesia, without any sedation. Lidocaine doses, time, oxygen saturation, peak expiratory flow (PEF) and the number of cough episodes were measured. Continuous assessment of the respiratory sensation was obtained with a visual analog scale. A total of 172 biopsies were performed in abnormal and normal areas. RESULTS: The procedure was long-lasting (mean +/- SD: 26.6 +/- 6.0 min), required high total doses of Lidocaine (660 +/- 107 mg) without any significant side effect, and was associated with significant decreases in O2 saturation from 98.5 +/- 1.4 to 96.1 +/- 2.5% and in PEF from 380 +/- 96 to 310 +/- 78 l/min. However, the cough counts were moderate and the majority of patients reported no respiratory discomfort. 62 hyperplasia, metaplasia, dysplasia and carcinoma in situ (CIS) were detected and the relative sensitivity of AB +/- white-light bronchoscopy (WLB) versus WLB alone was 3.75 for intraepithelial lesions corresponding to moderate dysplasia or worse. CONCLUSIONS: AB, a procedure that increases our ability to recognize preneoplastic lesions and early lung cancer, can be performed under local anaesthesia, without systemic sedation in patients at very high risk for lung cancer.

Ambulatory Care↗
PubMed2003

Management of hypoxemia during flexible bronchoscopy.

Under controlled conditions, FB is a safe procedure that has few significant adverse events. Significant hypoxemia may sometimes occur during FB despite the use of supplemental oxygen. UAO has been shown to be the dominant cause of hypoxemia during FB, and this is successfully managed with nasopharyngeal tube insertion. Other strategies that may need to be implemented include oxygen supplementation with intratracheal catheter, administration of sedation reversal medication, removal of the bronchoscope, bag-and-mask ventilation, and, rarely, endotracheal intubation and ventilation. Access to an anesthetist, availability of propofol, backup rigid bronchoscopy, and fluoroscopy are optional but desirable components in the bronchoscopy suite.

Bronchoscopy↗
PubMed2002

Bronchoscopy and needle biopsy techniques for diagnosis and staging of lung cancer.

Lung cancer is the leading cause of cancer deaths in the United States. The individual therapeutic approach and prognosis depends on accurate diagnosis and staging. Flexible bronchoscopy (FB) and transthoracic needle biopsy (TNB) are the most widely used techniques for this purpose. This article provides a critical overview of indications, diagnostic yield, and limitations of bronchoscopy and TNB in the diagnosis of lung cancer.

Biopsy, Needle↗
PubMed2001

The emerging role of flexible bronchoscopy in pediatrics.

Great advances had been made in rigid instrumentation, with the introduction of the glass rod telescope. With relatively few exceptions, however, bronchoscopy was still performed primarily for therapeutic indications, such as the removal of foreign bodies from the airway. It would remain for the introduction of the flexible bronchoscope to stimulate the widespread development of diagnostic bronchoscopy in pediatric practice.

Bronchi↗
PubMed2001

Rigid bronchoscopy in the twenty-first century.

Rigid bronchoscopy, a procedure more than 100 years old, now has been performed in three centuries. The "open tube" bronchoscope provides safe access to the lower airways and has proved to be compatible with newer, more sophisticated therapies as they have been introduced into the practice of bronchology. The twenty-first century surely will provide the bronchoscopist with exciting new diagnostic and therapeutic tools for the management of lung diseases, and it is likely that the rigid bronchoscope will continue to play an important role in delivering these tools to the airways. Pulmonologists need to appreciate the use of this classic instrument and prevent rigid bronchoscopy from becoming a forgotten art.

Bronchoscopes↗
PubMed1999

Role of bronchoscopy in AIDS.

The differential diagnosis of pulmonary disorders in the HIV-infected individual is broad. Clinical features and chest radiographs may point towards a diagnosis but cannot reliably establish one. It is important to know the conditions in which bronchoscopy, BAL, and TBB are likely to be diagnostic, just as it is to know when other invasive or noninvasive procedures may be more useful. Finally, the incidence of transmission of infections such as tuberculosis during bronchoscopy and cross-contamination of patients with an improperly sterilized bronchoscope, cannot be overemphasized.

Acquired Immunodeficiency Syndrome↗
PubMed1999

Flexible bronchoscopy in lung transplantation.

Bronchoscopy plays an indispensable role in lung transplantation. It is an essential part of the evaluation of potential lung donors, and it is the pivotal procedure in the management of lung transplant recipients. Although advances in immunodiagnostic methods may ultimately lead to noninvasive tests to detect rejection, histology will be the standard for some time, and transbronchial biopsy will remain the procedure of choice. Furthermore, the usefulness of bronchoscopy in the diagnosis of pulmonary infection after lung transplantation is unlikely to be supplanted by any emerging technique.

Bronchoscopy↗
PubMed1999

Role of bronchoscopy in massive hemoptysis.

Massive hemoptysis accounts for a minority of all patients with hemoptysis but poses a major challenge for the acute and long-term treatment. Massive hemoptysis can lead to asphyxiation and airway obstruction, shock, and exsanguination. Bronchoscopy plays an integral part in managing massive hemoptysis in diagnosis and treatment (Table 5). Specifically, bronchoscopy allows lateralization and more specific localization of bleeding that is critically important for effective management. Furthermore, acute control of bleeding can sometimes be achieved with instruments and catheters placed through the bronchoscope or by agents instilled into the airways through the bronchoscope.

Bronchoscopy↗
PubMed2000

Fiberoptic bronchoscopy for diagnosis and treatment.

Bedside fiberoptic bronchoscopy is a valuable tool in the diagnosis and treatment of various respiratory conditions in critically ill patients. The fiberoptic bronchoscope allows direct airway inspection, facilitating the diagnosis of benign and malignant airway lesions. In addition, pulmonary secretions or tissue samples can be collected using the bronchoscope and techniques that allow sampling of the lower airways with minimal or no upper airway contamination. Collection of lower airway samples is important in the diagnosis of pulmonary infiltrates in immunocompromised patients, in many patients with ventilator-associated pneumonia, and in selected patients with CAP. The fiberoptic bronchoscope can be used for therapeutic interventions, such as insertion of an endotracheal tube, removal of an aspirated foreign body, clearance of tenacious secretions, promotion of hemostasis in patients with hemoptysis, instillation of drugs, and assistance in the placement of tracheobronchial prostheses (i.e., airway stents). If proper preprocedural training and planning are done and the patient is monitored carefully during the procedure, fiberoptic bronchoscopy can be performed quickly and safely at the bedside in most critically ill patients.

Bronchoscopes↗
PubMed1998

Pediatric flexible bronchoscopy under conscious sedation: nursing considerations for preparation and monitoring.

Flexible bronchoscopy provides a powerful tool to evaluate pulmonary abnormalities in the pediatric population. Nursing involvement may range from age-appropriate preparation of the patient and family to administration of conscious sedation agents. Meticulous nursing assessment of the child, family, and environment facilitates identifying and meeting client needs related to flexible bronchoscopy. Preparation of the physical environment as well as physiological and psychological preparation of the child increase the likelihood of a positive experience. By increasing their familiarity with the procedure, sedation strategies, and monitoring standards, nurses increase the probability of safe and successful flexible bronchoscopic evaluations.

Anti-Anxiety Agents↗
PubMed1999

CT bronchoscopy.

CT bronchoscopy with volumetric rendering can play a significant role in patients with mediastinal/hilar tumor and lymphadenopathy. By localizing (tagging) tumor foci on the axial images, volumetric rendering allows the tumors to be seen through normal-appearing mucosa. Such images can guide the bronchoscopist in finding the ideal site to biopsy and allow the bronchoscopist to become more aggressive in the biopsy of more difficulty positioned lesions. In addition, delineation of normal extraluminal vessels and other vital anatomical structures potentially decreases biopsy complications. Although further research is needed to prove the value of CT bronchoscopy, preliminary work performed to date by the author and others indicates great promise.

Bronchoscopy↗
PubMed2005

[Bronchoscopy in childhood pulmonary tuberculosis].

Bronchoscopy can be helpful for microbiological diagnosis in children with primary tuberculosis and its yield is clearly enhanced by PCR detection. However,endoscopic sampling has a lower sensitivity rate than repeated gastric washings and probably sputum induction. Bronchoscopy is indicated in case of clinically and/or radiologically suspected endobronchial involvement, helps for restoration of normal airway diameter and bronchial wall injury follow-up. A few series on endoscopic findings according to the mode of presentation have been published in pediatric patients. In these studies endobronchial tuberculosis occurrence is described irrespective of clinical or radiological symptoms.

Bronchoscopy↗
PubMed1997

A case of rapidly expanding tuberculous lung cavity after bronchoscopy.

A non-smoking Asian woman with previously treated pulmonary tuberculosis presented with a recent onset unproductive cough and cavitating mass lesion on her chest X-ray which rapidly developed into a large tuberculous cavity after bronchoscopy. Acid-fast bacilli were isolated from the cavity and she responded very rapidly to standard anti-tuberculous chemotherapy. This unusual condition must be considered in patients who deteriorate after bronchoscopy.

Aged↗
PubMed1999

Midazolam sedation to produce complete amnesia for bronchoscopy: 2 years' experience at a district general hospital.

Patients may find bronchoscopy without sedation unpleasant. There is some evidence that patient satisfaction correlates with amnesia for the procedure. For several years we have used doses of midazolam sufficient to put patients lightly asleep hoping to produce complete amnesia. We looked at practical aspects of this technique over a 2-year period. We studied 337 consecutive patients. They were 219 men and 118 women of mean age 63 +/- 12.4 (SD). Sixty-seven patients were aged 75 years or over and the eldest was 86. Sixty-three patients were already hospital inpatients but the remainder were seen as day cases. Midazolam was given by slow i.v. injection over several minutes until the patient was judged to be lightly asleep. Patients were given supplemental oxygen (3 l min-1) and monitored by ECG and pulse oximetry. A note was made of the time at which they awakened, defined as when nursing staff felt the patients were awake enough to have a cup of tea and toast. Patients were asked if they had any memory of the procedure both on awakening and when seen a few days later to discuss the results. The procedures were carried out in a well-staffed Day Case Unit with a recovery area. The mean dose of midazolam used was 10.8 mg (mean +/- SD = 0.16 +/- 0.095 mg kg-1). The midazolam was given over a median of 4 min (range 1-15 min). Patients took 59 +/- 45 min (mean +/- SD) to wake up. Twenty-eight patients were given flumazanil to reverse the sedation (11 for concern over bleeding following biopsies, three for desaturation during and three after procedure, four as they were frail, two as they were restless, two as they were hypotensive after procedure and three for miscellaneous reasons). Only nine patients could remember any part of the procedure. Incremental doses of midazolam given slowly until patients are lightly asleep almost invariably produce complete amnesia for bronchoscopy. This is a safe technique but patients need careful monitoring and may require reversal of sedation with flumazanil.

Adult↗
PubMed2002

Success of lung transplantation without surveillance bronchoscopy.

BACKGROUND: No current evidence demonstrates improved survival or decreased rate of bronchiolitis obliterans syndrome (BOS) despite regularly scheduled fiberoptic bronchoscopy (FOB) with transbronchial biopsy and bronchoalveolar lavage (TBB/BAL) after lung transplantation. Reduced lung function detected with spirometry or oximetry in symptomatic and asymptomatic lung allograft recipients (LARs) may be a more appropriate indication for bronchoscopic sampling. HYPOTHESIS: Clinically indicated TBB/BAL without routine invasive surveillance sampling of the transplanted lung does not decrease survival or increase the rate of BOS in LARs. METHODS: We reviewed 91 consecutive LARs transplanted at Ochsner Clinic between January 1995 and December 1999. Clinical indications for FOB with TBB/BAL include 10% decline in forced expiratory volume in 1 second below baseline; 20% decrease in forced expiratory flow rate between 25% and 75% of the forced vital capacity; or unexplained respiratory symptoms, signs, or fever. Along with demographic and clinical data, 1-year and 3-year survival rates for these 91 LARs were compared with 5,430 LARs from the International Society for Heart and Lung Transplantation (ISHLT) Registry transplanted during the same 60-month period. Ten of the 91 patients did not survive to hospital discharge after transplantation. We divided the remaining 81 LARs into 2 subsets: Group A patients (n = 43) underwent zero to 1 TBB/BAL and Group B patients (n = 38) required more than 1 procedure. Demographic data, rejection, infection, and incidence of BOS were compared between groups. RESULTS: The 1-year and 3-year survival rates in the Ochsner LAR cohort were 85% and 73%, respectively, vs 72% and 57% in the ISHLT cohort p < 0.01. The relative risks of death in the Ochsner group at 1- and 3-years were 0.56 (0.35-0.91) and 0.66 (0.48-0.92), respectively, p < 0.05. The median (range) follow-up was 910 days (60-1,886) for Group A and 961 days (105-1,883) for Group B, p = not significant. We observed twice as many patients with cystic fibrosis and twice as many pneumonia episodes in Group B. The rate of acute rejection in each group was not statistically different. The cumulative incidence of BOS was increased in Group B at 1 year and at 3 years (5% and 56%) when compared with Group A (3% and 13%), p < 0.01. CONCLUSIONS: Based on the findings from this observational, single-institution study, clinically indicated TBB/BAL without routine surveillance sampling of the lung allograft is unlikely to pose greater risk than does regularly scheduled bronchoscopy after lung transplantation.

Adult↗
PubMed2002

Bronchoscopy--how and when?

At the Royal Brompton Hospital, we perform over 200 flexible bronchoscopies per year in children. We will be presenting a series of five articles describing various aspects of our clinical and research practice. This first article is about the basics of how and when to perform flexible bronchoscopy. It highlights aspects of training, preparation of the patient and the equipment required. It discusses anaesthesia and gives practical details on how to actually use the bronchoscope, as well as detailing techniques of lavage, brushings and biopsy. Particular attention is paid to indications and contraindications, as well as potential complications.

Anesthesia, General↗
PubMed2003

Bronchoscopy and infection.

Bronchoscopy can be useful to diagnose respiratory infections in the immunocompromised and those with problematic cystic fibrosis or with focally abnormal chest X-rays. Its role in paediatric tuberculosis is controversial with scanty objective evidence. As it is an invasive procedure, the following should be asked: what question am I trying to answer by bronchoscopy? Will the answer justify the risks of the procedure?

Bronchoalveolar Lavage Fluid↗