Refractive errors in Nigerians: a hospital clinic study.
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Twenty-eight eyes of people who have successfully worn hydrophilic contact lenses were monitored during a period after removal of their contact lenses. The results are compared to similar studies of wearers of non-flexible contact lens. While both curvature and refractive changes in a number of eyes stabilized at about one week, others did not stabilize until three weeks or more.
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Measurements of the refractive errors in 55 strabismic patients--one eye with visual acuity of 0.8 or better and the other with reduced vision, 0.4 or less due to amblyopia, and performed at roughly two-year intervals during growth and development to approximately age 25 years--showed that the eye with normal visual acuity was significantly more myopic with age, whereas there was no appreciable change in the average refractive error of the amblyopic eye. Both eyes of a control group of patients of similar age having normal distant vision and orthophoria were more myopic with age. In this group there was an insignificant difference in the change in refractive error of one eye compared with its fellow during comparable periods of time.
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The first classical twin studies, recognizing the potential of comparing findings in identical twins, have previously been reported to be those by Siemens and by Merriman, both published in 1924. However, we would like to bring to attention a study performed by Walter Jablonski, 2 years earlier (1922), investigating the contribution of heredity to refraction in human eyes. Jablonski examined the eyes of 52 twin pairs and by comparing the size of within-pair differences between identical and nonidentical twins was able to infer the heritability of a trait. Therefore, this is likely to be the first reported classical twin study.
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PURPOSE: To evaluate ocular parameters that may predispose to the development of branch retinal vein occlusion (BRVO). METHODS: This prospective study included patients with unilateral BRVO evaluated in the authors' clinic. The mean period from the acute phase was 2.29 +/- 1.57 years (range 1-6 years). All patients underwent a complete ophthalmologic examination including subjective refraction, axial length measurements, and keratometry readings. The fellow eye served as a control in each patient. The variables of interest were compared between the affected eye and the fellow eye using the parametric t-test and the nonparametric Wilcoxon test. RESULTS: Twenty-four consecutive patients (14 women, 10 men, mean age 62.4 years) were included in the study. The mean axial length in the affected eye was significantly shorter compared to the mean fellow eye length. No difference was found between the two eyes in mean subjective refraction or mean keratometry readings. CONCLUSIONS: The authors found that eyes with BRVO have a shorter axial length compared to the fellow eye in the same patient.
PURPOSE: To examine changes in spherical equivalent over a 5-year period in persons 43 to 84 years of age. METHODS: All people 43 to 84 years of age and living in Beaver Dam, Wisconsin, in 1988 were invited for a baseline examination (1988-1990) and a 5-year follow-up examination (1993-1995). Refractions were determined according to the same protocol at both examinations. Aphakic and pseudophakic eyes were excluded as well as eyes with best corrected Snellen visual acuity of 20/40 and worse. After exclusions, refraction was obtained on 3007 right eyes and 3012 left eyes of the 3684 people participating in both examinations. RESULTS: Right and left eyes behaved similarly. Spherical equivalent became more positive in the youngest subjects and more negative in older subjects. After adjusting for other factors, the 5-year change in spherical equivalent of those 45, 55, 65, and 75 years of age was +0.15, +0.18, +0.10, and -0.07D, respectively. Severity of nuclear sclerosis was related to the amount of change. Those with mild nuclear sclerosis at baseline had a change of +0.2 D, whereas those with severe nuclear sclerosis had a change of -0.5 D. The amount of change was also related to gender, diabetes, and age at onset of myopia. It was unrelated to education and baseline spherical equivalent. CONCLUSIONS: Changes in spherical equivalent over a 5-year period were small. Before the age of 70, people became more hyperopic. After the age of 70, people became more myopic. Much of the myopic change may be related to increasing nuclear sclerosis.