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Effect of prolonged neck muscle vibration on lateral head tilt in severe spasmodic torticollis.

UNLABELLED: Short term vibration of the dorsal neck muscles (10-35 s) is known to induce involuntary movements of the head in patients with spasmodic torticollis. To investigate whether neck muscle vibration might serve as a therapeutic tool when applied for a longer time interval, we compared a vibration interval of 5 seconds with a 15 minute interval in a patient with spasmodic torticollis with an extreme head tilt to the right shoulder. Head position was recorded with a two camera optoelectronic motion analyzer in six different test conditions. Vibration regularly induced a rapid change of head position that was markedly closer to a normal, upright posture. After 5 seconds of vibration, head position very quickly returned to the initial position within seconds. During the 15 minute interval, head position remained elevated. After terminating vibration in this condition, the corrected head position remained stable at first and then decreased slowly within minutes to the initial tilted position. CONCLUSIONS: (1) In this patient, muscle vibration was the specific sensory input that induced lengthening of the dystonic neck muscles. Neither haptic stimulation nor transcutaneous electrical stimulation had more than a marginal effect. (2) The marked difference in the change of head position after short and prolonged stimulation supports the hypothesis that spasmodic torticollis might result from a disturbance of the central processing of the afferent input conveying head position information-at least in those patients who are sensitive to sensory stimulation in the neck region. (3) Long term neck muscle vibration may provide a convenient non-invasive method for treating spasmodic torticollis at the central level by influencing the neural control of head on trunk position.

Female↗

Transitory postural vasomotor dysfunction in the finger after short term hand vibration.

The transitory effects of hand vibration (ah, w = 3.16 m/s2 during three minutes) on postural vasomotor functions of skin capillary blood flow rate in the finger were studied by the local 133xenon washout technique in ten men with vibration induced white finger (VWF), nine men professionally exposed to hand-arm vibration but without finger symptoms (HAV), and eight male controls (MC). The following postural vasomotor functions were measured: (a) the vasomuscular, non-neurogenic autoregulation, tested by raising the finger 20 cm; (b) the local venoarteriolar vasoconstrictor axon reflex, tested by lowering the finger 40 cm; and (c) the central sympathetic vasoconstrictor reflex elicited by central baroreceptors and tested by changing the body posture from supine to sitting upright. Before short term vibration the vasoconstriction elicited by central baroreceptors was increased in VWF (p less than 0.01) and normal in HAV (p greater than 0.10). The local axon reflex and the autoregulation functioned normally in VWF and HAV (p greater than 0.30). Three minutes after vibration, autoregulation was abolished and the functions of the central and local sympathetic vasoconstrictor reflexes were equally impaired in all three groups (p less than or equal to 0.01). All three vasomotor functions were completely restored 60 minutes after vibration in MC (p greater than 0.10) and also 30 minutes after vibration in one male control (p greater than 0.20). The results indicate a hyperreactivity of the central sympathetic nervous system in VWF, and a transitory, impaired function of digital arterioles after short term vibration in all groups.

Adult↗

Vibration induced neurophysiological and electron microscopical changes in rat peripheral nerves.

This study was conducted to clarify the effects of vibration on the peripheral nerves. Rat tails were exposed to vibration (acceleration 56.9 m/s2, frequency 60 Hz, amplitude 0.4 mm for two or four hours daily, six days a week. The maximum motor conduction velocity (MCV), the amplitude of evoked response, and the motor distal latency were measured on rat tail nerves every two months. Thin sections of tail nerves were examined under the electron microscope after 200, 500, and 800 hours of vibration. Neurophysiological and ultrastructural changes in tail nerves increased with the dose of vibration. In the groups exposed to vibration the MCVs were significantly reduced after a vibration time up to 400 hours, whereas the motor distal latency was not delayed significantly until 600 vibration hours. The ultrastructural changes were (1) detachment of the myelin sheath from the axolemma, (2) constriction of the axon, (3) protrusion of the myelin sheath into the axon, (4) accumulation of vacuoles in paranodal regions, and (5) dilatation of the Schmidt-Lanterman incisures. The ultrastructural changes induced by vibration in the paranodal regions and myelin sheaths were possibly responsible for the reduction in MCVs.

Animals↗

Quantitative thermal perception thresholds relative to exposure to vibration.

OBJECTIVES: To assess the risk of disturbed thermal perception relative to exposure to vibration, to investigate a possible exposure-response relation and to analyse a possible relation between thermal perception and sensory symptoms. METHODS: The study was based on a cross section of 123 male workers exposed to vibration and 62 male workers who were not exposed. Thermal perception of cold, warmth, and heat pain was bilaterally determined from the thenar eminence by the method of limits. Perception of cold and warmth were also tested in the second digit. Personal energy equivalent exposure to vibration was measured for all subjects. Vibration was measured in accordance with International Standards Organisation (ISO) 5349 and assessed separately for the left and right hand. RESULTS: Combining exposure times and intensities gave the left hand an 0.80 exposure to vibration compared with the right. The risk of having contracted reduced thermal perception was increased at all test sites. The risk was higher for the thenar measurements than the finger measurements. A yearly extra contribution of 4000 mh/s(2) in cumulative exposure increases the risk of contracting a wider neutral zone by 18% (95% confidence interval (95% CI) 1.06 to 1.32) for the right and 18% (1.05 to 1.32) for the left hand side. Subjects with symptoms of nocturnal paraesthesia had a rate ratio (95% CI) of 2.80 (1.17 to 6.67) for the right hand and 2.72 (1.12 to 6.63) for the left hand for increased neutral zones at the thenar eminence. CONCLUSIONS: The results indicate thermal sensory impairment related to cumulative exposure to vibration. The effect appeared at vibration levels below the current guiding standard. Quantitative sensory testing of thermal perception offers the chance to assess this specific hazard to the peripheral sensorineural system associated with hand intensive work entailing vibration.

Adult↗

Effect of chest wall vibration on breathlessness in normal subjects.

This study evaluated the effect of chest wall vibration (115 Hz) on breathlessness. Breathlessness was induced in normal subjects by a combination of hypercapnia and an inspiratory resistive load; both minute ventilation and end-tidal CO2 were kept constant. Cross-modality matching was used to rate breathlessness. Ratings during intercostal vibration were expressed as a percentage of ratings during the control condition (either deltoid vibration or no vibration). To evaluate their potential contribution to any changes in breathlessness, we assessed several aspects of ventilation, including chest wall configuration, functional residual capacity (FRC), and the ventilatory response to steady-state hypercapnia. Intercostal vibration reduced breathlessness ratings by 6.5 +/- 5.7% compared with deltoid vibration (P less than 0.05) and by 7.0 +/- 8.3% compared with no vibration (P less than 0.05). The reduction in breathlessness was accompanied by either no change or negligible change in minute ventilation, tidal volume, frequency, duty cycle, compartmental ventilation, FRC, and the steady-state hypercapnic response. We conclude that chest wall vibration reduces breathlessness and speculate that it may do so through stimulation of receptors in the chest wall.

Adult↗

Fluctuations in plantar flexion force are reduced after prolonged tendon vibration.

The purpose of the study was to examine the effect of prolonged vibration on the force fluctuations during a force-matching task performed at low-force levels. Fourteen young healthy men performed a submaximal force-matching task of isometric plantar flexion before and after Achilles tendon vibration (n = 8, vibration subjects) or lying without vibration (n = 6, control subjects) for 30 min. The target forces were 2.5-10% of the previbration maximal voluntary contraction force. The standard deviation of force decreased by a mean of 29 +/- 20% across target forces after vibration, whereas it did not decrease significantly in control subjects (-5 +/- 12%). This change was significantly greater compared with control subjects (P < 0.01 for both). Power spectral density of the force was predominantly composed of signals of low-frequency bandwidth (<or =5 Hz) with few higher frequency components. In vibration subjects, there was a significant decrease in power in the frequency range < or =2 Hz after vibration. The decrease in power at this frequency range was linearly related to the decrease in the force fluctuations (r = 0.96, P < 0.001). The results indicate that prolonged Achilles tendon vibration reduces the fluctuations in plantar flexion force in the frequency range < or =2 Hz during low-level contractions. It suggests that Ia afferent inputs contribute to the low-frequency force fluctuations in plantar flexion.

Achilles Tendon↗

Facilitation of triceps brachii muscle contraction by tendon vibration after chronic cervical spinal cord injury.

One way to improve the weak triceps brachii voluntary forces of people with chronic cervical spinal cord injury may be to excite the paralyzed or submaximally activated fraction of muscle. Here we examined whether elbow extensor force was enhanced by vibration (80 Hz) of the triceps or biceps brachii tendons at rest and during maximum isometric voluntary contractions (MVCs) of the elbow extensors performed by spinal cord-injured subjects. The mean +/- SE elbow extensor MVC force was 22 +/- 17.5 N (range: 0-23% control force, n = 11 muscles). Supramaximal radial nerve stimuli delivered during elbow extensor MVCs evoked force in six muscles that could be stimulated selectively, suggesting potential for force improvement. Biceps vibration at rest always evoked a tonic vibration reflex in biceps, but extension force did not improve with biceps vibration during triceps MVCs. Triceps vibration induced a tonic vibration reflex at rest in one-half of the triceps muscles tested. Elbow extensor MVC force (when >1% of control force) was enhanced by vibration of the triceps tendon in one-half of the muscles. Thus triceps, but not biceps, brachii tendon vibration increases the contraction strength of some partially paralyzed triceps brachii muscles.

Adult↗

Stance- and locomotion-dependent processing of vibration-induced proprioceptive inflow from multiple muscles in humans.

We performed a whole-body mapping study of the effect of unilateral muscle vibration, eliciting spindle Ia firing, on the control of standing and walking in humans. During quiet stance, vibration applied to various muscles of the trunk-neck system and of the lower limb elicited a significant tilt in whole body postural orientation. The direction of vibration-induced postural tilt was consistent with a response compensatory for the illusory lengthening of the stimulated muscles. During walking, trunk-neck muscle vibration induced ample deviations of the locomotor trajectory toward the side opposite to the stimulation site. In contrast, no significant modifications of the locomotor trajectory could be detected when vibrating various muscles of the lower as well as upper limb. The absence of correlation between the effects of muscle vibration during walking and standing dismisses the possibility that vibration-induced postural changes can account for the observed deviations of the locomotor trajectory during walking. We conclude that the dissimilar effects of trunk-neck and lower limb muscle vibration during walking and standing reflect a general sensory-motor plan, whereby muscle Ia input is processed according to both the performed task and the body segment from which the sensory inflow arises.

Action Potentials↗

Vibration-induced postural posteffects.

It generally is known that vibration of various muscles in free-standing subjects evokes a spatially oriented postural response. Furthermore, it recently has been shown that when a vibratory stimulus is terminated, a powerful involuntary contraction of the previously vibrated muscle often occurs that, under the isotonic condition, is accompanied by movement of a limb. The aim of this study was to explore effects of a low-amplitude mechanical vibration, applied in a seated position, on the standing posture. The 30-s vibration was applied bilaterally at the ankle level to anterior or posterior tendons and at the cervical level in front or back of the neck, at one site only at a time. Center of pressure trajectories were monitored during quiet stance for </=19 min after the offset of vibration, and these measurements were compared with a previbration control trial. The results clearly indicate that vibration produced in all subjects strong, long-lasting dynamical modification of posture mainly in the anterior-posterior direction. Spatial orientation of the induced postvibratory shift in posture was dependent on the vibration side. We conclude that sustained Ia sensory inflow, evoked by vibration, has a powerful after-effect on the motor system at the postural level.

Adult↗

Detection of vibration transmitted through an object grasped in the hand.

A tool or probe often functions as an extension of the hand, transmitting vibrations to the hand to produce a percept of the object contacting the tool or probe. This paper reports the psychophysical results of a combined psychophysical and neurophysiological study of the perception of vibration transmitted through a cylinder grasped in the hand. In the first part of the psychophysical study, 19 subjects grasped a cylinder, 32 mm diam, with an embedded motor that caused vibration parallel to the axis of the cylinder. The relationship between threshold and frequency was the traditional U-shaped function with a minimum between 150 and 200 Hz. Except a study by Békésy in which subjects grasped a rod that vibrated parallel to the skin surface, thresholds above 20 Hz were lower and the slopes were steeper than any reported previously. Thresholds were <0.01 microm in some subjects. Data from both the psychophysical and the neurophysiological studies suggest that detection performance at frequencies >20 Hz was based on activity in Pacinian afferents. The extreme sensitivity compared with previous reports may have resulted from differences in contact area, direction of vibration, contact force, and the shape of the stimulus probe. The effects of each of these variables were studied. At 40 and 300 Hz (frequencies near the lower and upper end of the Pacinian range) thresholds were 9.8 and 18.5 dB (68 and 88%) lower, respectively, when subjects grasped the cylinder than when a 1-mm-diam probe vibrated perpendicular to the skin. These differences were accounted for as follows: 1) thresholds at a single fingerpad obtained with the large cylindrical surface were, on average, 20 and 60% lower, respectively, than thresholds with the punctate probe; 2) thresholds at the palm were, on average, 15 and 40% lower, respectively, than at the fingerpads; 3) thresholds obtained when the subjects grasped the cylinder averaged 40 and 20% less, respectively, than when the cylinder contacted only the palm; 4) thresholds with the cylinder contacting two fingers were 10 and 30% lower, respectively, than thresholds with the cylinder contacting a single finger; and 5) thresholds with vibration parallel to the skin surface were, on average, 10 and 30% lower, respectively, than thresholds with vibration perpendicular to the skin. Contact force, which was varied from 0.05 to 1.0 N, had no effect.

Hand↗

Effect of chest wall vibration on dyspnea in patients with chronic respiratory disease.

The effect of chest wall vibration on dyspnea at rest was investigated in 15 patients with severe chronic respiratory diseases. The magnitude of their baseline dyspnea was 17.9 +/- SE 3.3 mm on a 150-mm visual analog scale. One hundred hertz out-of-phase vibration (OPV; inspiratory intercostal muscles vibrated during expiration and expiratory intercostal muscles vibrated during inspiration) increased dyspnea an average of 21.9 +/- SE 7.8 mm (p < 0.05). One hundred hertz in-phase vibration (IPV; inspiratory intercostal muscles vibrated during inspiration and expiratory intercostal muscles vibrated during expiration) decreased dyspnea an average of 6.9 +/- SE 2.8 mm (p < 0.05). Changes in the respiratory pattern and arterial blood gas determinations elicited by 5-min IPV were investigated in eight of the 15 patients. Tidal volume was significantly increased in all eight of these patients. Respiratory frequency was decreased in seven patients and increased in one. Functional residual capacity, measured before and during the application of IPV for a period of about 10 breaths, was increased in one patient and decreased in the remaining seven. PaCO2 decreased by 1.3 +/- 1.0 mm Hg (p < 0.05), from 49.6 +/- 8.4 mm Hg; PaO2 increased by 3.4 +/- 2.3 mm Hg (p < 0.05), from 67.7 +/- 12.7 mm Hg. The results indicate that in-phase chest wall vibration decreased pathologic dyspnea in patients with chronic respiratory disease and suggest that the effects on respiratory sensation are mediated by afferent information from chest wall respiratory muscles to supraspinal centers.

Aged↗

Effect of steroids on increased permeability of blood vessels of the stria vascularis after auditory ossicle vibration by a drill in otologic surgery.

OBJECTIVES: The vibration caused by drills used for middle ear surgery is considered one of the causes of postoperative sensorineural deafness. Seki et al reported that when drill-induced damage was created in the auditory ossicles of guinea pigs, permeability across the capillary vessels in the stria vascularis increased significantly with the duration of drill-induced vibration. The present study was undertaken to examine changes in permeability across the stria vascularis capillaries following vibration in experimental animals pretreated with steroids, with the goal of developing a method of preventing a vibration-induced increase in permeability across these capillaries. METHODS: After an intravenous dose of hydrocortisone and horseradish peroxidase, the auditory ossicles of guinea pigs were vibrated with a drill for 60 seconds. RESULTS: Intravenous steroid administration before vibration reduced the leakage of horseradish peroxidase from the stria vascularis capillaries after vibration. CONCLUSIONS: The findings suggested that steroids suppress the increase in permeability across the stria vascularis capillaries that results from drill-induced vibration.

Animals↗

Mechanisms underlying the production of carapace vibrations and associated waterborne sounds in the American lobster, Homarus americanus.

American lobsters produce carapace vibrations, which also lead to waterborne acoustic signals, by simultaneously contracting the antagonistic remotor and promotor muscles located at the base of the second antenna. These vibrations have a mean frequency of 183.1 Hz (range 87-261 Hz), range in duration from 68 to 1720 ms (mean 277.1 ms) and lead to waterborne sounds of similar frequencies. Lobsters most often produce these signals using only one pair of muscles at a time and alternate between the muscles of the left and right antennae when making a series of vibrations. Occasionally, they vibrate their carapace by simultaneously contracting both sets of muscles. While the remotor muscle is required for producing carapace vibrations, the promotor appears to play a secondary role. Electrical stimulation of the remotor, but not the promotor, results in the production of vibrations, while lesions of the remotor, but not promotor, eliminate the ability of lobsters to vibrate their carapace. Lobsters of all sizes and both sexes produce these signals when startled, grasped or threatened. However, at this time, the behavioral significance of vibration and/or sound production by American lobsters is not known.

Animals↗

Temporal pattern cues in vibrational risk assessment by embryos of the red-eyed treefrog, Agalychnis callidryas.

The embryos of red-eyed treefrogs, Agalychnis callidryas, use vibrations transmitted through their arboreal egg clutch to cue escape hatching behavior when attacked by egg-eating snakes. Hatching early increases the risk of predation in the water, so embryos should avoid it unless they are in danger. We exposed egg clutches to intermittent vibrations with different combinations of vibration duration and spacing to examine the role of simple temporal pattern cues in the escape hatching response. Stimuli were bursts of synthetic white noise from 0 to 100 Hz, including the range of frequencies with substantial energy in snake attacks, and had approximately rectangular amplitude envelopes. Embryos hatched in response to a small range of temporal patterns and not in response to many others, rather than hatching to most vibrations except for certain patterns perceived as safe. Neither cycle length nor duty cycle predicted hatching response, except at extreme values where no hatching occurred; the highest energy stimuli elicited little or no hatching. Both vibration duration and inter-vibration interval strongly affected the hatching response. The highest levels of hatching were to durations of 0.5 s combined with intervals of 1.5-2.5 s, and hatching decreased gradually with increasing difference of either duration or interval from these most effective stimuli. Vibration duration and interval appear to function as two necessary elements of a composite cue, rather than as redundant cues. This increases response specificity and reduces the range of stimuli that elicit hatching, likely reducing the chance of hatching unnecessarily in a benign disturbance. Vibration-cued hatching in A. callidryas embryos offers an opportunity to experimentally assess the behavioral decision rules underlying an effective and costly anti-predator defense.

Animals↗

The prevalence and extent of vibration sensitivity impairment in men with chronic ethanol abuse.

We have studied vibration sensitivity impairment in 100 male alcoholic veterans and 52 control subjects who had no etiologic factors for peripheral neuropathy. Vibration sensitivity was quantitated at the hallux with the Vibration Sensitivity Tester. Alcoholic subjects had impairment of vibration sensitivity when compared with control subjects (p less than .001). This difference persisted when a covariance analysis was performed which included age (coefficient +/- SE: 1.40 +/- 0.35 units, p less than .001). Asymptomatic subjects also had vibration sensitivity impairment (p less than .01). In subjects whose ages were greater than or equal to 45 years, 47% of the alcoholics had poorer vibration sensitivity than did any of the controls. Among the alcoholic subjects there were significant correlations of the vibration perception threshold with both age (r = 0.39, p less than .001) and drinking duration (r = 0.35, p less than .001). In multiple regression analyses these associations remained significant (p less than .05). These data indicate that vibration sensitivity impairment is highly prevalent in alcoholic subjects and that impairment may even occur in those who are asymptomatic.

Adult↗

[The vibration of the handle-bars of a motorcycle in running on the paved road (author's transl)].

Lately, in our country, daily motorcycling mail deliverers suffered from vibration hazards have been increasing. The vibration level of the handle of motorcycles was measured in order to evaluate its hazardous effects. The tested motorcycle with a 90 cc engine was selected among many motorcycles for daily use. Running test was made on the chasis dynamometer and asphalt roads. Following results were obtained. 1) The direction showing the maximum value of vibrations acceleration is in other directions than, X, Y, Z of ISO (International Organization for Standardization). 2) The maximum vibration acceleration level exceeds the exposure guidelines of ISO and its frequency is an accordance to the engine speed of the motorcycle in running. 3) The levels in the frequency ranges from 6 to 20 Hz and from 50 to 100 Hz are liable to induce vibration hazards. 4) The stronger the gripping power, the more the vibration acceleration level in the frequency range of 6-20 Hz and, on the contrary, the vibration acceleration level decreases in the range of 50-100 Hz. 5) The rubber grips of this motorcycle are not effective for abating the vibration on the frequency spectrum less than 125 Hz or 200 Hz.

Humans↗

[Effects of local vibration exposure on the finger blood flow (author's transl)].

The purpose of the present study was to clarify the physiological response of peripheral blood vessels when some vibrational stimuli were given to five healthy young men (21-22) continuously and intermittently. The vasoreaction was observed on each subjects after the exposure to vibration at frequencies 18, 32, 64 and 125 Hz with acceleration level at 5 g (peak value). In the pulse wave height of left and right arms, a specified tendency was not found while a larger variation was observed. After continuous exposures, pulse wave propagation velocity at the left arm showed a decreasing tendency at lower frequencies, but in the right arm, such a tendency did not appear. After intermittent exposures, it showed decreasing tendencies at both the left and righ arms, but such remarkable decreases were not observed as was seen at the left arm after continuous exposure. Variation analysis on the pulse wave showed that the propagation velocity was related significantly (p less than 0.01) to the subject and to the frequency during continuous and intermittent exposures of the left and right arms. These results indicate that the lower frequency is one of the factors which cause the vibrational disease, and there was a person who is liable to vibrational disease. When compared with the intermittent vibration exposure, the continuous vibration exposure produced significantly lower pulse wave propagation velocities in the left arm. This finding indicates that the intermittent vibration relieves an accumulation of the effects by vibration.

Adult↗

[On vibration hazards of chipping-hammer operators in an iron foundry. Part 2. Results of the hygienic control].

We previously reported that the working and health conditions of vibrating tool operators in an iron foundry were investigated in 1975 and vibration hazards were observed to occur frequently in workers operating chipping-hammers powered by compressed air. After that, we instituted medical treatment for the afflicted workers and improvement of working conditions in the foundry, and have performed annual medical examinations for four years. In this paper, the course of hygienic control and the change in the medical findings of twenty-four chipping-hammer operators are reported. 1. The following measures were taken to improve the working conditions of chipping-hammer operators and therapy for patients (Table 1): (1) The operating time of vibrating tools, including chipping-hammer, was limited to two hours per day. The casting process was improved to diminish the flashes that are the objects of chipping-hammer operation. For the purpose of reducing the vibration transmitted to the operator, a servo-arm that has a servomechanism for the chipping-hammer was developed and introduced. (2) Infrared lamps in the foundry and air curtains at the doorway were installed for keeping the chipping-hammer operating area warm. A warm room was set up in the foundry for providing warmth during rest periods and protective clothing against the cold was provided. (3) Workers who displayed health disturbances by medical examinations were treated during the cold season from November to April by periodic visits to the clinic or extended hospitalization, or transferred to job without vibration exposure, according to their stage of disease. Preventive treatment with vasodilator and bubble bath was performed in winter for the chipping-hammer operators. 2. In order to estimate the effect of these countermeasures, annual medical examinations were conducted in March 1975, March 1976, April 1977 and March 1978. Such subjective symptoms as Raynaud's phenomenon, finger numbness, finger listlessness, heavy-headedness, forgetfulness, irritability and hearing disorder showed a tendency for improvement, but other complaints did not (Tables 2-4). The improvement of Raynaud's phenomenon is considered to be due not merely to the countermeasures but also to reducing the chance of provocation and therefore the countermeasures should not be overestimated as a factor of recovery of vibration hazards. Of the functional tests, a tendency for improvement was recognized in sensory functions and peripheral circulatory functions, but not in motor functions (Tables 5, 6). However, the course of recovery was not fast and some advanced cases, especially those using chipping-hammers for more than ten years, showed less improvement after hospital treatment (Table 7, Fig. 1). This indicates the importance of hygienic control which enables vibration hazards patients to have early diagnosis and treatment. Furthermore, in order to eradicate the vibration hazards in the cast metal industry, a drastic reform of the finishing process is considered to be necessary.

Adult↗