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The neurotoxicology of lead.

In the past six years, our research group has investigated the relationship between lead exposure and mental and behavioural development. This has been carried out through studies in children and animals. Earlier studies in children have shown that associations might be expected between environmental exposure to lead and various aspects of cognitive and behavioural development. Our study has examined and continues to examine, a cohort of children sub-divided into three groups according to the level of lead exposure during early 'in utero' development. Data amassed to date includes measurement of psychometric function and post natal development, together with biochemical measures of lead exposure. Assessment will continue through to early scholastic performance and will include measurement of deciduous tooth lead concentration as an integrated measure of long term exposure. In addition to these studies in children, a series of neurochemical studies have been carried out using a rat model of lead exposure. Data obtained from both our own neurochemical experiments and those of other groups indicate an extremely complex plethora of neurotoxic actions of lead.

Amino Acids↗

Indications for dental anesthesia.

The need for general anesthesia management in the dental office applies to a variety of patient types. They are essentially ASA class I or class II risks with a diversity of treatment needs from the simple extraction of a deciduous tooth to multiple treatment procedures. The training, skill, and experience of the provider of anesthesia as well as the adequacy of the facilities will determine the choice of management and ultimately the nature of total patient care.

Anesthesia, Dental↗

Separation of fused primary incisors: report of case.

A case of a child with a maxillary primary left lateral incisor fused to a supernumerary was presented. The teeth were separated and restored using stainless steel crowns with composite facings. The described treatment permitted a maximum level of esthetics, function, and cleansability of the primary dentition, without compromising the permanent dentition.

Crowns↗

Ameloblastic fibrodentinoma: report of case.

The classification, progression, and treatment of the mixed odontogenic tumors remain controversial. In the case reported here, examination of a patient who presented with delayed eruption of a primary central incisor led to the discovery of an impacted incisor and an associated isolated radiolucency.

Child, Preschool↗