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PubMed2004

Bilateral anterolateral thigh flaps for large-volume breast reconstruction.

Autologous tissue reconstruction of a large breast in patients who are not candidates for a TRAM flap is a difficult problem. We present a case report of the use of bilateral free anterolateral thigh (ALT) flaps for immediate reconstruction of a unilateral large breast in a patient who had a previous abdominoplasty. Use of ALT flaps allows two or three surgical teams to work simultaneously, does not require intraoperative patient repositioning, has minimal donor-site morbidity, and can provide ample malleable soft tissue for breast reconstruction. These are advantages compared to the use of gluteal donor sites. The disadvantages include more conspicuous donor-site scarring on the anterior thighs.

Adult↗

PubMed2006

One-stage reconstruction of large scalp defects: anterolateral thigh flap.

Seven patients with large scalp and calvarial defects underwent reconstruction with free tissue transfer. Patients fell into two groups according to etiology: tumoral (five) or traumatic (two). A single type of free flap was used in each patient, i.e., the anterolateral thigh flap. Duraplasties with the flaps' vascularized fasciae were performed in two patients with minor calvarial defects, and nonvascularized fasciae were used in another two, with a cranioplasty using methylmethacrylate. One postoperative death and one venous congestion necessitating exploration were observed. The explored anastomosis revealed occlusion of the venous anastomosis; drainage with a venous graft into the neck veins was performed. Minor tissue loss with secondary healing was observed in the flap. Extensive scalp defects often necessitate challenging reconstructive procedures. Single-stage reconstruction with good qualified tissue is possible with a free tissue transfer. The anterolateral thigh flap provides a large amount of tissue with decreased donor-site morbidity and good cosmetic results.

Adult↗

PubMed1993

Electrical stimulation of vastus medialis and stretching of lateral thigh muscles in patients with patello-femoral symptoms.

Thirty patients with unilateral patello-femoral symptoms and a hypotrophic vastus medialis muscle were treated with transcutaneous electrical stimulation of the vastus medialis obliquus and stretching of the lateral thigh muscles twice daily for 10 weeks. Before and after treatment the position of the patella at fixed knee flexion angles and the area of the vastus medialis and vastus lateralis muscles were studied by computed tomography. Isokinetic quadriceps torque was registered with a Cybex II Dynamometer. An evaluation with a functional knee score was carried out. The healthy contralateral leg served as control in all the examinations. Clinically two-thirds of the patients had improved after 10 weeks of treatment and this improvement remained at follow-up 3.5 years later. The area of the vastus medialis and the quadriceps torque of the treated leg increased significantly, while the area of the vastus lateralis and the position of patella did not change. We conclude that transcutaneous electrical muscle stimulation of the vastus medialis and stretching of the lateral thigh muscles might be of benefit in patients with patello-femoral symptoms and a hypotrophic vastus medialis. An improvement after 10 weeks of treatment seems to predict a good long-term result.

Adolescent↗

PubMed2001

The internal calcar septum (femoral thigh spur) in computed tomography and conventional radiography.

OBJECTIVE: The femoral "thigh spur", a cortical septum in the region of the lesser trochanter of the human femur, was first described and named by the German anatomist Merkel in 1874, but it was never examined in detail. To evaluate the frequency and the shape of this structure, a combined anatomical and radiological study was performed using saw-cuts from specimens, high-resolution CT and conventional radiography. DESIGN: Thirty human cadaveric femora of central European origin were analyzed by high-precision computed tomography (CT) using thin slices and high-resolution imaging. The CT data were image processed with thresholding to obtain a reconstruction of high-density bone formations and for three-dimensional imaging. Additionally three macerated femur specimens were cut exactly corresponding to the CT slices. The computed images were validated with the anatomical saw-cuts. RESULTS: A dense trabecular ridge protruding endosteally from the posteromedial cortex was found in all femora. This cortical septum reaching from the femoral neck to the distal part of the lesser trochanter separated the femoral cavity from the cancellous bone inside the lesser trochanter. On conventional radiography the femoral thigh spur could be visualized best in the frog-lateral view of the hip. CONCLUSION: The internal calcar septum is a constant cortical structure. It should be recognized when radiographs or CT images of the proximal femur are interpreted. It could be of importance for metaphyseal fitting of an endoprosthetic stem.

Aged↗

PubMed2006

Reconstruction of abdominal wall by whole thigh flap.

Closure of extensive abdominal wall defects can be a very challenging task as there are no known large local or free vascularized flaps available that could cover the entire abdomen. Tensor fascia latae (TFL) has been widely used for abdominal wall reconstruction [Hill HL, Nahai F, Vasocnez LO. The tensor fascia lata myocutaneous free flap. Plast Reconstr Surg 1978;61:517-22]. However, the dimensions of the standard TFL flap limit its use in cases of large full thickness abdominal wall defects. Therefore, we have used an ingenious technique of raising the entire thigh skin as a fasciocutaneous flap (whole thigh flap) based on the concept of fusion of angiosomal territories, to reconstruct such a defect following excision of a large abdominal wall tumour.

Abdominal Wall↗

PubMed2006

First web-space reconstruction by the anterolateral thigh flap.

Four patients with severe contracture of the first web space were treated with an anterolateral thigh perforator flap. The flap size ranged from 10 to 13 cm in length and from 7 to 8 cm in width. The donor site was closed directly and thinning of the flap was performed in all cases. All flaps survived and there were no re-explorations. Web space opening was maintained over the follow-up period. There was an average postoperative increase of the angle of the first web space of 61 degrees. The thinned anterolateral thigh flap provides a pliable vascularized tissue for resurfacing the skin after release of severe contracture of the first web space and represents a reliable alternative to other flaps.

Adult↗

PubMed2003

Steroids prevent late extension of radiofrequency lesions in the thigh muscle of infant rats: implications for pediatric ablation.

INTRODUCTION: Marked late enlargement of radiofrequency (RF) lesions may occur in immature myocardium, suggesting that late proarrhythmic effects may occur in infants and small children undergoing RF ablation. Because late lesion extension may be involved in this phenomenon, we evaluated the impact of corticosteroids on the healing of RF lesions created in the thigh muscle of 29 infant Wistar rats (30 days; 55 g). METHODS: Lesion dimensions and histological characteristics were assessed acutely (n = 11), and at 30 days in controls (n = 11, 183 g) and rats (n = 7, 173 g) receiving hydrocortisone after ablation and betametasone for 29 days. Acute (n = 16) and chronic (30 days; n = 5) lesions were also evaluated in adult Wistar rats (300 g). RESULTS: Acutely, lesions in adults and infants were well demarcated from the surrounding tissue. In adults, chronic lesions did not increase in size and were well demarcated histologically. Controls and treated infant rats did not differ with respect to the gross appearance of chronic lesions. Late lesions doubled in size (20 mm in diameter) and were poorly demarcated from the surrounding tissue, exhibiting multiple collagen strands extending from the lesion into normal muscular tissue. In the treatment group, healing was markedly delayed and the extent of collagen proliferation was significantly less than controls. CONCLUSION: RF lesions created in the thigh muscle of infant rats reveal late enlargement and invasion of normal muscle by intense collagen proliferation. Steroids seem to limit late extension of RF lesions. These findings may have implications for RF ablation procedures in pediatric populations.

Animals↗

PubMed1998

In vivo pressure profiles of thigh-length graduated compression stockings.

BACKGROUND: The aim of the study was to assess whether the appropriate pressure profile is generated by thigh-length graduated compression stockings in human subjects. The effect of leg posture on the pressure profile was assessed in three commonly used brands of graduated compression stockings. METHODS: The study involved 17 human volunteers from the Department of Orthopaedic Surgery. Three different brands of stockings commonly recommended for the prevention of deep vein thrombosis were applied to each individual and the interface pressure profile under the stocking was measured. The effect of posture was assessed by comparing the interface pressure profile with the subject supine and in standing and sitting positions. RESULTS: Appropriate median pressure profiles were achieved only with the subject standing or supine. In the sitting position with the knee flexed, a high median interface pressure in excess of 28 mmHg was generated at the popliteal fossa. Overall, inconsistent performance was found in all three brands of stockings; fewer than 30 per cent of the pressure readings fell within 20 per cent of the 'ideal'. Reversed pressure profile was observed in over 70 per cent of subjects. CONCLUSION: Thigh-length graduated compression stockings may be most effective in bedridden patients. Knee-length stockings may be more suitable for the prevention of deep vein thrombosis in ambulant patients.

Bandages↗

PubMed1997

Cutaneous hemangioma of the thigh: prenatal diagnosis.

We report a case of cutaneous hemangioma of the thigh detected by prenatal ultrasound. A hypoechoic homogeneous mass, filled with low-density echoes, was visualized on the posterior aspect of the right thigh, close to the genital region, at 36 weeks. Low-velocity arterial flow was detected within the mass by color and pulsed Doppler and the diagnosis of cutaneous hemangioma was suspected. No other anomalies were detected and the pregnancy evolved uneventfully to term. The prognosis and management of this condition are discussed.

Adult↗

PubMed2001

Coverage of an ischial pressure ulcer with an interpolated contralateral posterior thigh fasciocutaneous flap.

The ipsilateral posterior thigh flap has become one of the workhorses for the closure of ischial pressure ulcers. We treated a 40-year-old paraplegic patient with a right ischial pressure ulcer, in whom all ipsilateral flap options had been expended or were precluded by scars. A contralateral left posterior thigh fasciocutaneous flap interpolated subcutaneously across the midline provided successful coverage.

Adult↗

PubMed2002

Clinical experience of 1284 free anterolateral thigh flaps.

The past decade has witnessed yet another rebirth in reconstructive surgery with the introduction of the so-called "perforator flaps". The demonstration of safe harvest of skin flaps based on dissection of cutaneous pedicles regardless of the course taken (through muscle or septum) has been revolutionary in allowing much greater choice in donor sites. Based on our experience in 1284 cases, the anterolateral thigh (ALT) region has proven itself to be an ideal donor site with reliable vascularity, ease of harvest and tremendous versatility. Inclusive in this flap is a large cutaneous territory, multiple components (adipofascial, muscle, fascia and skin) and possibility of chimeric applications. Although particularly useful in the head and neck (911 cases), the ALT flap was applied to reconstruct defects throughout the body. Donor site morbidity is limited as well. In short, the anterolateral thigh flap represents one of the most useful soft tissue flaps for free tissue transplantation.

Anastomosis, Surgical↗

PubMed2003

Vascularized femoral nerve graft with anterolateral thigh true perforator flap for massive defects after cancer ablation in the upper arm.

Massive resection of soft-tissue sarcoma in the elbow region often results in loss of long segments of the brachial artery and median nerve, as well as a wide soft-tissue defect. With conventional nerve grafts and revascularization of the arm, forearm and hand function is poor because nerves cannot be regenerated over the long nerve gap in the high elbow region. The authors used a long vascularized nerve graft and found it effective for reconstruction of upper arm function. This paper describes the first application of a free vascularized femoral nerve graft and a free anterolateral thigh true perforator flap based on the lateral circumflex femoral system, to repair elbow and forearm function. Long vascularized femoral nerve grafts of over 12 cm can be obtained, and an anterolateral thigh flap can be harvested from the same donor area.

Adult↗

PubMed1981

[Longitudinal data of physical growth of healthy children. Lengths of trunk, hand, forearm, upper arm, whole arm, lower leg, thigh and whole leg of children aged 2,5 to 15 years. (author's transl)].

From 1968-78 a longitudinal study was performed concerning development of lengths of trunk, hand, forearm, upper arm, whole arm, lower leg, thigh and whole leg in 709 healthy boys and 711 girls aged 2,5 to 15 years. In boys the mean increase in lengths of trunk amounted to 17.7 cm, of hand to 8.1 cm, of forearm to 12.2 cm, of upper arm to 16.1 cm, of whole arm to 36.8 cm of lower leg to 21.5 cm, of thigh to 27.3 cm, and of whole leg to 54.0 cm. The corresponding lengths in girls amounted in 16.9 cm, 7.2 cm, 11.0 cm, 14.0 cm, 32.6 cm, 18.7 cm, 24.5 cm, and 46.4 cm. Lengths investigated increase almost linearly between 3 and 11 years of age both in boys and girls. Beginning with 12 years boys have an increased development of all lengths when compared with girls.

Adolescent↗

PubMed1998

Free combined anterolateral thigh flap and vascularized fibula for wide, through-and-through oromandibular defects.

Through-and-through oromandibular defects require the greatest amount of soft-tissue volume among the transfers for head and neck defects. A new method, a large anterolateral thigh flap combined with a vascularized fibula graft in a chimera fashion, has been used for two patients with wide through-and-through oromandibular defects. Among the candidates for such a large skin flap, the anterolateral thigh flap seems to be the best, for the following reasons. (1) Its pedicle, the lateral circumflex femoral system, has several major branches of equal size of anastomosis of the peroneal vessels. (2) As the majority of such patients with multiple previous surgery have lost recipient vessels near the mandible, the longest vascular pedicle is required. (3) There is no need for positional changes, and simultaneous flap elevation with the tumor resectioning is possible. (4) Use of the fibula allows for reconstruction of the entire mandible, if necessary. (5) Some of the shortcomings of individual donor sites for massive composite osteocutaneous flaps are minimized, because each component consists of two donor sites. (6) Operating time for this flap elevation is minimized, compared to that for massive composite osteocutaneous flaps, because the individual components can be obtained simultaneously by two teams.

Aged↗

PubMedDate not supplied

Deep vein thrombosis prophylaxis: the effectiveness and implications of using below-knee or thigh-length graduated compression stockings.

Potential complications of reduced mobility in both acute and chronically ill patients continue to challenge nurses on a daily basis. Deep vein thrombosis (DVT) is one of the most serious of these complications. Graduated compression stockings, also known as antiembolism stockings, are among the most commonly available and accepted methods of external compression for the prophylaxis of DVT. Currently, there are 2 lengths of graduated compression stockings in common use, thigh-length and below-knee. Although thigh-length stockings are widely perceived to be more effective in prophylaxis, difficulties associated with therapeutic application and maintenance are often encountered in different clinical settings. Below-knee stockings are easier to apply and maintain and appear to be tolerated better by patients. The aim of this article is to examine existing support for both lengths of stockings in terms of their effectiveness in DVT prophylaxis and to discuss the implications for practice.

Bandages↗

PubMed2002

Deep vein thrombosis prophylaxis: the effectiveness and implications of using below-knee or thigh-length graduated compression stockings.

Bandages↗

PubMed1989

Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection models.

Animal studies that compare antibiotics have used only a limited number of doses administered at intervals chosen without regard for their pharmacodynamic effects of pharmacokinetic profiles. We compared the relative efficacy and potency of three beta-lactams and two aminoglycosides in lung and thigh-infection models in neutropenic mice by defining the maximum attainable antimicrobial effect at 24 h (Emax) and the total dose required to reach 50% of maximum effect (P50) at several dosing intervals. For beta-lactams, Emaxs were similar, whereas P50s increased 10- to 50-fold with longer intervals in both models. Aminoglycosides were significantly more bactericidal in the lung than in the thigh, and dosing interval had little impact on P50s in either model. Recognizing the variable impact of dosing interval on efficacy for different classes of antibiotics is mandatory for the proper design and interpretation of comparative trials.

Animals↗

PubMed1988

Electrical stimulation versus voluntary exercise in strengthening thigh musculature after anterior cruciate ligament surgery.

Twenty patients who had undergone anterior cruciate ligament reconstructive surgery were placed randomly and independently in an Electrical Stimulation Group (n = 10) or Voluntary Exercise Group (n = 10) to compare the effectiveness of these two muscle-strengthening protocols. Patients in both groups used simultaneous contraction of quadriceps femoris and hamstring muscles during a training regimen that consisted of either voluntary exercise or electrical stimulation trials five days a week for a three-week period within the first six postoperative weeks. After patients completed the training regimen, bilateral maximal isometric measurements of gravity-corrected knee extension and flexion torque were obtained for both groups and percentages were calculated. Results showed that patients in the Electrical Stimulation Group finished the three-week training regimen with higher percentages of both extension and flexion torque when compared with patients in the Voluntary Exercise Group (extension: t = 4.35, p less than .05; flexion; t = 6.64, p less than .05). These results indicate that patients in an electrical stimulation regimen can achieve higher individual thigh musculature strength gains than patients in a voluntary exercise regimen when simultaneous contraction of thigh muscles is prescribed during an early phase of postoperative rehabilitation.

Adult↗