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Multiple organ manifestations in thromboangiitis obliterans (Buerger's disease). A case report.

Thromboangiitis obliterans (TAO) occurs almost exclusively in young male smokers. Its involvement of the small and medium-sized arteries and veins leads to ischemic complaints and/or changes in the extremities. The possibility of organ involvement is a matter of controversy. The authors report a case of TAO with multiple organ involvement, including myocardial, splenic, and cerebral infarctions; pulmonary embolisms; and probable intestinal ischemia during a twenty-three-year course.

Adult↗

Splenic arteriovenous fistula with infarcted spleen.

A 25-year-old woman developed epigastralgia and abdominal bruit in the left hypochondrium. Radiologic investigation included Doppler ultrasonography, angiography and computed tomography and revealed splenic artery aneurysm and arteriovenous fistula resulting in an almost totally infarcted spleen.

Adult↗

[Ruptured spleen during bacterial endocarditis. 2 cases (author's transl)].

Splenectomy was performed in two patients amongst a group of 120 suffering from bacterial endocarditis. In the first case, rupture of the spleen followed rupture of a partially thrombosed splenic vein and bacteriological specimens were negative despite the presence of multiple infarcted areas, certain of which were suppurative. In the second case surgery was possible before rupture of the spleen. The latter was the site of numerous abcesses, one of which was in the process of fissuration, and bacteriological specimens were positive. The course in both cases was favourable. Twenty two other cases have been found in the literature with 15 deaths. Whilst the prevalence of such complications remains low, their severity is such that routine surveillance of the kidney should be the rule in infectious endocarditis. The methods of such surveillance are discussed, the mechanism of such complications not being fully elucidated: the respective role of splenic infarction, splenic abcess and immunological factors remains to be determined.

Adolescent↗

Transcatheter arterial embolization--major complications and their prevention.

A thorough account is given of the complications of embolization techniques in nonneurovascular areas, including hepatic infarction, renal and splenic abscess formation. Infarction of the urinary bladder, gallbladder, stomach, and bowel are discussed. Suggestions are offered to prevent complications from embolization where possible. Specific agents for embolization are detailed and their relative merits are compared; ethyl alcohol has recently gained popularity for treating esophageal varices and infarcting renal tumors. Care is advocated when using alcohol in the renal arteries; employing this agent is currently contraindicated in the celiac and mesenteric arteries. Coils and balloon systems are also described along with their potential complications.

Abscess↗

The spleen in inflammatory pancreatic disease.

As the pancreas and the spleen lie in close proximity, splenic complications may occur in the course of acute or chronic pancreatitis in the form of isolated splenic vein thrombosis, intrasplenic pseudocysts, splenic rupture, infarction, and necroses as well as splenic hematoma and severe bleeding from eroded splenic vessels. Diagnosis is usually made under emergency conditions and is mainly based on ultrasound and computed tomography plus bolus injection and splenoportography. Additionally, ultrasound- or computed tomography-guided needle aspiration of fluid collection in the left upper quadrant may be helpful. Such conditions may be life threatening and, according to the increasing number of case reports, may be more frequent than is thought. They must be added to the list of other important extrapancreatitic complications such as shock and respiratory and renal failure. This review summarizes the present knowledge on splenic complications in acute and chronic pancreatitis for purposes of timely diagnosis and treatment and draws attention to the need for follow-up examinations of the spleen by imaging procedures in the course of acute and chronic pancreatitis.

Hematoma↗

[Hepatic hemorrhagic infarction in eclampsia and HELLP Syndrome associated with the antiphospholipid syndrome].

A 33 year-old woman developed eclampsia with HELLP syndrome. Laboratory results revealed lupus anticoagulant and anticardiolipin antibodies. Imaging tests showed liver and spleen infarctions. The patients was given enoxaparin and supportive care and there was a good evolution. We discuss some aspects about liver infarction and its association with toxemia of pregnancy and the antiphospholipid syndrome.

Adult↗