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Role of glucosinolates in the causation of liver haemorrhages in laying hens fed water-extracted or heat-treated rapeseed cakes.

Glucosinolates were removed from whole rapeseed by a hot-water extraction procedure or depleted by heat treatment. When laying hens were maintained for three months on diets containing about 300 g kg-1 of these rapeseed cakes, the incidence of liver haemorrhages detected at post mortem examination was similar to that in birds maintained on 300 g kg-1 commercial rapeseed meal and significantly greater than in control birds fed soya-based diets. The effectiveness of glucosinolate extraction or depletion was determined by chemical analysis and by histological examination of the thyroid glands. Histologically the haemorrhages were similar after feeding extracted and commercial rapeseed meals. Diets containing mixtures of nitriles and glucosinolates severely depressed food intake and egg production but did not cause a greater incidence of haemorrhages than the other rapeseed products tested. Mortality from causes other than liver haemorrhage was higher with the diets containing rapeseed and this suggests that rapeseed has a more generalised effect on the body's defence mechanisms. These observations suggest that other factors in rapeseed meal, alone or acting with glucosinolates, may be responsible for inducing liver haemorrhages in laying hens.

Animal Feed↗

[Histological characteristics of the intraorbital glands of pheasants with tuberculosis].

For the first time in the country are investigated histologically lacrimal and Harderian glands of pheasants, affected by tuberculosis, raised in pens. By histological analysis were reported the results of the cell reactivity in the affected by the tubercular process tissues and organs. Under the influence of the mycobacteria and their disintegration products the tissues react specifically. In pheasants, affected by tuberculosis are established destructive processes in the intraorbital glands. Mainly in the connective tissue of the glands are observed tubercular knots, which morphologically differ from these in the hen. In the interlobular tissue, in the interacinar and peritubular connective tissue exist strongly expressed infiltration with cells of the lymphoid series, phagocytes and heterophils, as a result of the affected-tissue reactivity, on account of the local and diffusional spreading of the tubercular bacillus in the glands.

Animals↗

Aetiology of food-related oral lesions in chickens.

Brown Leghorn chickens fed on a mash diet developed ulcerated oral lesions with extensive epithelial erosion and large colonies of bacteria. Some birds had lesions by six weeks old and by 30 weeks oral lesions were present in all birds fed on a mash diet. These lesions occur infrequently in birds fed a pelleted diet and the relatively extensive lesions shown by birds on a mash diet heal quickly (in many cases within two weeks) when the birds are transferred to a pelleted diet. The cause of the lesion is unknown but there was no evidence for food impaction, mechanical damage to the epithelium, specific dietary constituents or blocked salivary ducts. The lesions may be due to poor oral hygiene which results from the lack of mechanical stimulation of the oral epithelium to which fine particles of mash adhere.

Animal Feed↗

[A hemorrhagic-anemic syndrome with dermatitis in broiler chickens].

Eleven successive deaths of broiler chickens affected with dermatitis (Staphylococcus aureus) preceded by anaemia and muscular haemorrhages, are reported as occurring in Belgium. All of these cases could be traced to a single flock of broiler breeders. The depletion of lymphoid cells in the bursa, thymus and spleen was a striking feature. Infectious Bursal Disease virus as triggering or causative agent, could not be demonstrated. The pathological changes showed a marked resemblance to similar syndromes which were recently reported in broilers (1, 2, 3, 4).

Anemia↗

[Dystrophic muscular fibers in the muscles of certain breeds of birds].

The occurrence of pathologically changed muscular fibers in some wild species of birds and in economically important domesticated species of birds is described. The hydrops of muscular fibers, necrosis and atrophy with connective tissue infiltration in muscular bundles were detected in breast and thigh muscles in wild birds, e. g. in raven, pigeon and pheasant. The same pathological processes were also found in domesticated species, e. g. in guinea fowl, less often in geese and duck. Their incidence in turkeys and laying types of fowl was more frequent, they were observed most often in muscles of broiler hens. Fission of muscular fibers, very thin, but also hypertrophic fibers and resorption of necrotic fibers were detected in hens besides the above changes. The described histological picture is confronted with the picture of hereditary myodystrophy in chickens.

Animals↗

Elevated bile acids in the plasma of laying hens fed rapeseed meal.

A simple procedure was developed for the estimation of bile acid taurine conjugates in fowl plasma. Laying hens fed a diet containing rapeseed meal (RSM) (400 g kg-1) for 12 weeks had higher bile acid levels (154 mumol litre-1) than hens fed a control soyabean diet (116 mumol litre-1) (P less than 0.01). The incidence of liver haemorrhages was higher (34.8 per cent) in RSM-fed hens than in controls (21 per cent), but the severity of the lesions did not correlate with the bile acid concentration in affected birds. Histological examination of sections from livers of RSM-fed birds did not reveal significant hepatocyte degeneration outside the immediate vicinity of the haemorrhage. Canalicular bile plugs were never seen. The incidence of liver haemorrhages (13 per cent) and plasma bile acids (85 mumol litre-1) were lower in hens fed a diet containing beta-aminopropionitrile (0.5 g kg-1), a known lathyrogen. Acute treatment of hens with the hepatotoxin alpha-naphthyl isothiocyanate over four days induced necrosis of hepatocytes and resulted in elevated bile acid concentrations (262 mumol litre-1) compared with controls (73 mumol litre-1) given arachis oil. It was concluded that laying hens fed high levels of RSM develop cholestasis but the toxic principle is not known.

Animal Feed↗