[Acute manifestations due to allergen contact. Apples and nuts can be poisons in neurodermatitis].
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Atopic dermatitis is a multifactorial skin disease with complex aspects and a wealth of abnormal immunological and nonimmunological findings. Abnormalities of skin morphology and function, disturbances of the essential fatty acids metabolism and in the cyclic AMP system as well as immunological abnormalities are shortly described. In analogy to asthma and rhinitis, the author propose to divide atopic dermatitis according to the presence or not of an associated respiratory allergy and specific IgE sensitization in 3 groups, namely in an "extrinsic", an "intrinsic" and a "mixed" type.
Considering the different types of mothers under the aspect of distribution of power in the relationship between mother and child, we find the dominating form of upbringing mainly during the postwar years. This form comprises both the authoritative and the over-protective ways of bringing up. As a reaction, we now observe an excessive increase of the submissive type of mothers tending to compliant education: With the help of a free upbringing, they want to make their children capable of expressing their feelings freely. As these children are not told their personal limits, they become unadaptable to their social environment and develop a thirst of power. These phenomena are increasingly observed among children with atopic dermatitis.
The irritational disposition of the skin was studied in a control group of 12 healthy persons, 8 patients with neurodermitis, 11 hairdressers with occupational dermatitis and 11 nurses with occupational dermatitis by using the Duhring-chamber-scarification test. For comparison, the alkali resistance test was also carried out. The results show that with the alkali resistance test the irritational disposition towards tensides may not be judged. The present findings show that the increased irritational disposition toward detergent substances seems to be a constitutional factor which favors the development of occupational dermatitis in hairdressing and nursing jobs; with the patient suffering from atopic dermatitis, one must presume an increased irritational disposition towards tensides in most cases.
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We report on psychosomatic aspects regarding out-patient and hospital treatment of atopic dermatitis, including information concerning the disease, motivation for psychotherapeutic forms of treatment (relaxation, diagnostic and therapeutic conversation), as well as psychosomatic indicators for the discharge from hospital.
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The author presents his personal therapeutic principles with regard to atopic dermatitis using glucocorticoids antibiotics, and antihistamines. The role of diet as well as treatment with evening primrose seed oil are discussed.
In view of numerous insufficient modes of treatment of atopic dermatitis, Hartung and Pürschel elaborated a more agreeable way of treatment without side effects including all the multifactorial aspects of the disease and being as complete and as pleasant as possible. The dermatologic climate therapist practised at the Hospital for Allergy and Skin Diseases on the North Sea island of Norderney founded by Hartung in 1953. Treatment of affected children or adults - over 20,000 patients so far - starts with a complete general medical and dermatological check-up. The aim of our therapy is to withdraw topical and systemic applications of glucocorticoids and to achieve intervals free of signs and symptoms. The favorable effects of the North Sea climate are the basis of extensive dermatological treatment and psychological guidance of the patients. There have been no side effects observed.
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Absolute number of eosinophilic leucocytes, total IgE level, and specific IgE antibodies against the environmental antigens cock's foot, house-dust, and house-dust mite (dermatophagoides pteronyssinus) were obtained from 25 patients suffering from atopic dermatitis at the beginning as well as towards the end of hospital treatment in the maritime climate of the North Sea. Initially the absolute eosinophilic leucocytes were increased. According to the improvement of the atopic skin lesions, there was a significant decrease up to normal rates in several cases at the end of hospital treatment. The increased number of eosinophilic leucocytes observed at the beginning of therapy was correlated to the total IgE level. On an average, pathologic initial rates of total IgE going along with acute lesions decreased during hospital treatment; but this observation may be statistically accidental, the cutaneous lesions, however, completely disappeared. Elevated initial rate of antigen-specific IgE antibodies, as well, showed obvious reduction, but they did not reach normal values in any case. According to update knowledge, the IgE level in serum seems to be predominantly controlled by a multifactorial genetic system.
121 patients who had been treated because of atopic dermatitis (AD) in 1967-1970 (at the age of 1-10 years) at the Department of Dermatology, University Hospital of Zurich (in- and outpatient department), were controlled by means of questionnaires, 62 of them were also personally examined. Interesting items were localisation of the AD, influences on its course, as well as micromanifestations. Infantile atopic eczema was most often localized on the face (65.3%) and on the hair-covered head (34%). The elbows and popliteal regions were attacked in 27% each. In 63% of the patients, personal examination revealed typical lesions of AD, mostly occurring on the elbows (59%) and popliteal areas (56.4%). Other common localisations were: wrist (34%), neck (31%), ankles (31%), eyelids (21%), as well as the areas behind the ears (13%). 73% of the patients had dry skin, only 8% showed a fatty one. In 66.7%, we observed the eczematic form of reaction, in 66.7% the lichenoid type, and in 10.3% the pruriginous form. 26% of the patients actually suffering from AD had perlèche or cheilitis exfoliativa, 54% of them showed follicular keratosis. 17% of the examined persons, who actually did not suffer from classic AD, had perlèche, 56% of them follicular keratosis. We discuss the possible interrelation between these findings and ichthyosis vulgaris which often occurs concomitantly. The course of AD is influenced by seasons in 77%. Deterioration of the skin conditions was predominantly found in periods of psychical stress (22%), with nervousness (33%), or with sweating (51%).(ABSTRACT TRUNCATED AT 250 WORDS)