[Chronically ill due to the environment. Does study involvement help?. Interview by Dipl.-Biochem. Petra Eiden].
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Case definitions of the same phenomenon may be different for different purposes. Case definitions usually become more specific over time as more information about the condition becomes available. Idiopathic environmental intolerance is one of many labels for a heterogeneous group of conditions in which subjects describe multiple symptoms that are attributed to exposure to extremely low doses of common chemicals. Dr. Kreutzer presents issues in case definition for clinical purposes and for population-based studies, and makes recommendations for the clinician and for the public health investigator.
It has been postulated that psychophysiologic mechanisms may account for symptom generation in IEI. In this review, the similarity of IEI and panic disorder symptoms are noted. The results of various challenge studies, both with known panicogenic substances and self-identified triggers, are examined. Available data are consistent with the premise that IEI symptoms have a psychophysiologic basis.
Idiopathic environmental intolerance (IEI) is an acquired condition with multiple symptoms associated with diverse environmental factors tolerated by most persons, not explained by known medical or psychiatric disorders. Data from clinical and epidemiologic samples show a robust association between IEI and lifetime psychiatric disorder, particularly mood, anxiety, somatoform, and personality disorders. IEI has not been associated with lifetime substance use disorders or psychotic disorders. The relationship of IEI and psychiatric disorder is important to acknowledge because it alerts clinicians to the fact that many persons diagnosed with IEI suffer treatable emotional illnesses, and because it suggests that some persons with mental illness are being misdiagnosed when their symptoms are misinterpreted as evidence of IEI.
Dr. Hodgson summarizes what is known about human symptoms and discomfort in the built environment, and formulates several critical hypotheses that show striking parallels to the questions arising from discussions of the IEI/MCS syndrome.
This chapter addresses the diagnostic evaluation and treatment of the patient presenting with idiopathic environmental intolerance (IEI). Clinicians with different views about the pathogenesis of IEI may agree on clinical management programs aimed at improved symptom control and functional ability.
This chapter focuses on the psychotherapy of individuals who suffer distress from functional somatic syndromes; specifically, idiopathic environmental intolerance (IEI). While patients believe environmental intolerances cause their distress, its origin is treated as psychological, mediated through psychophysiological systems and mechanisms associated with the stress response. Factors considered include stress and trauma premorbid to the alleged onset of IEI; somatization and its expression through affective, anxiety, and somatoform disorders; personality disorders and associated psychological defenses; motivation for the sick role; and iatrogenic suggestion and reinforcement of unsubstantiated toxicogenic theories and treatments. Psychotherapies include behavioral desensitization, cognitive-behavioral therapy, cognitive therapy, and psychotropic medications. The greatest challenge in treatment is to overcome the patient's disabling belief in a toxicogenic explanation for his or her symptoms.
The causes of occupational dermatosis were analysed in 27 dental nurses examined at The Nofer Institute of Occupational Medicine during the years 1995-99. Contact sensitisation (at least one positive epidermal test) was found in 18 subjects (66.7%). Occupational allergic dermatitis was induced most frequently by: glutaraldehyde (7 positive patch tests), nickel (7), benzalkonium (4), formaldehyde (4), fragrances (4), chromium compounds (3), glyoxal (3), and thiuram (3). In the authors' opinion, dental nurses are nowadays sensitised to other chemical compounds than it used to be in the past. The present components of disinfectants (aldehydes, quaternary ammonium bases), metals and rubber are the major etiologic agents that induce occupational allergy.
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The purpose of this work was to define the diagnostic methods in unspecific syndromes of exogenous intoxication and their use for conduction of medical classification in the foci of polychemical and unknown chemical affections. Detection of unspecific syndromes of extreme pathologic process in persons affected by dangerous chemical substances will contribute to organization of two-stage medical support, will facilitate the conduction of medical classification, determination of type and volume of medical assistance.
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