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PubMed1991

[Experience with the management of pyogenic liver abscesses by percutaneous transhepatic puncture and drainage].

The authors treated forty-two patients with liver abscesses guided by computer tomography or ultrasound percutaneous transhepatic puncture or drainage from January 1 1983, to 1989 December 31. Closed aspiration or drainage was done in 42 patients altogether 56 times. Three patients died (3/42 = 7.2%), postdrainage complications happened in 9 cases (9/42 = 21.4). Operative intervention was necessary in 11 patient after the percutaneous procedure (11/42 = 26.2%). The authors wrote about the technics particularly of the percutaneous puncture or drainage. The authors are considering the method as an effective treatment for pyogenic liver abscesses if the personal and technical circumstances are given.

Drainage↗
PubMed1978

Treatment of amoebic liver abscess with tinidazole and metronidazole.

20 patients with amoebic liver abscess, confirmed by aspiration of typical amoebic 'pus', were treated in random order with either tinidazole or metronidazole in a dose of 2g once daily for 2 days. Clinical, radiological, and biochemical follow-up was done for 1 month. One patient, given metronidazole, absconded and 19 completed the trial. Complete recovery occurred in all 10 patients given tinidazole but in only 5 of the 9 given metronidazole (p = 0.05). Patients on tinidazole required repeat aspirations less frequently than those on metronidazole. Mild gastrointestinal side-effects occurred in 1 patient on metronidazole but in none on tinidazole. From the present study, tinidazole appears to be a more effective, better tolerated drug with a more rapid therapeutic effect than metronidazole.

Adult↗
PubMed2005

Liver abscess caused by magA+ Klebsiella pneumoniae in North America.

Taiwan has witnessed an emerging syndrome of liver abscess caused by Klebsiella pneumoniae carrying the magA gene required for exopolysaccharide web biosynthesis. We report a patient transferred from Alaska to Washington State with a magA(+) K. pneumoniae liver abscess and describe a simple approach for recognition of these hypervirulent strains.

Alaska↗
PubMed1999

Protection of hamsters from amebic liver abscess formation by a monoclonal antibody to a 150-kDa surface lectin of Entamoeba histolytica.

We examined the effects of passive immunization with a monoclonal antibody (EH3015) that recognizes a 150-kDa surface lectin of Entamoeba histolytica on amebic liver-abscess formation in hamsters. The hamsters were inoculated i.p with 0.1, 1.0, or 10 mg of EH3015 at 24 h prior to an intrahepatic challenge with 10(5) trophozoites of E. histolytica. In hamsters treated with 1.0 and 10 mg of EH3015 the incidence of liver abscesses was significantly reduced. These results demonstrate that monoclonal antibody EH3015 can prevent the development of amebic liver abscesses and that the 150-kDa lectin may be a protective antigen on the surface of E. histolytica.

Animals↗
PubMed1993

Correlation between antiamoebic IgG and autoreactive anti-IgG in amoebic liver abscess cases.

IgG isolated and purified from a healthy human serum through Sephadex G-200 and protein A CL 4B sepharose chromatography was used for detection of its own antibodies and correlated with the antiamoebic antibody titres in amoebic liver abscess cases. The mean titres with standard deviation of the self reactive antibodies to serum IgG both ALA cases and healthy controls show a highly significant difference, and antiamoebic antibody titres (IgG) are very much correlated with the autoreactive anti IgG titres in amoebic liver abscess cases. This correlation suggests that as antiamoebic IgG levels reach to its maximum, autoreactive anti IgG are produced to switch off antiamoebic anti IgG production in amoebic liver abscess cases.

Animals↗
PubMedDate not supplied

[Septic shock during the immediate post-partum period revealing a liver abscess in a woman with Crohn's disease].

Liver abscess is a rare complication of Crohn's disease. We report one case in a 27 year-old woman, presenting as a sepsis after delivery. Crohn's disease was quiescent at presentation. Pregnancy was the only predisposing condition. An intestinal fistula was diagnosed by ultrasonography. The patient was treated by antibiotics, bowel resection and surgical drainage of the abscess.

Adult↗
PubMed2003

Ruptured amebic liver abscess.

A 20 years old male was referred from a district hospital having a refractory amebic liver abscess, not responding to metronidazole and aspiration. At presentation, he had pain in the right upper abdominal quadrant (RUAQ) with guarding and rigidity, accompanied by fever, vomiting and dyspnea. A diagnosis of ruptured amebic liver abscess (ALA) was made. The patient was managed successfully with ultrasound (US)-guided percutaneous catheter drainage (PCD) and metronidazole.

Adult↗
PubMed1990

[Diagnosis and treatment of liver abscesses using computerized tomography].

Employment of computer-aided tomography and ultrasonic scanning in 74 patients with liver abscesses helped rapidly detect the condition and identify its type. The sensitivity of ultrasonic scanning in the diagnosis of liver abscesses has made up 90.77 percent, specificity 86.44 percent, in computer-aided tomography these values have been the same and made up 97.96 percent. Closed transcutaneous interventions monitored by computer-aided tomography and ultrasonic scanning in these patients helped reduce the number of complications from 48.78 to 27.27 percent, mortality rates from 29.27 to 3.03 percent, hospitalization periods by 13.21 days, i. e. by 20.6 percent, as against the patients treated by traditional surgical methods.

Adolescent↗
PubMed1985

Pyogenic liver abscess in children: a report of three patients and review of the literature.

Three children with pyogenic liver abscess seen over a period of 2 years are reported. Their immune status was normal and no underlying causes were detected. The clinical picture was characterized by fever, abdominal pain and tender hepatomegaly. Abscesses were solitary in two children and multiple in the third. One child died within 12 h of admission, the other two recovered completely. Recent literature on pyogenic liver abscess is reviewed.

Child↗
PubMed1984

Successful medical management of a Yersinia enterocolitica liver abscess.

An insulin-dependent diabetic patient with liver abscess secondary to Yersinia enterocolitica without septicemia is described. He had the diagnosis established by transhepatic needle aspiration of the abscess cavity. Successful management was accomplished with antibiotic therapy alone.

Anti-Bacterial Agents↗
PubMed1985

Low dose tinidazole in the treatment of amoebic liver abscess.

Thirty-six patients with uncomplicated amoebic liver abscess were treated with low dose tinidazole 1.2 g to 1.5 g in a single or divided doses, and aspiration of the abscess. No drug related toxicity was noted. All patients responded well and there was no relapse or treatment failure.

Adult↗
PubMedDate not supplied

Liver abscess caused by Streptococcus milleri.

There is now convincing evidence that Streptococcus milleri is an important cause of pyogenic liver abscesses. The clinical course is no different from that of pyogenic infections of the liver arising from other causes. A positive blood culture should alert the clinician to the possibility of hepatic suppuration. Treatment consists of drainage by laparotomy or percutaneous aspiration combined with approximately 6 weeks of penicillin administration. Patients with liver abscesses who receive metronidazole may not respond if S. milleri is the infecting organism.

Aged↗
PubMed1983

Differential diagnosis between amoebic liver abscess and acute cholecystitis.

The Research Committee of the World Organization of Gastroenterology has gather information regarding the etiology of acute abdominal pain. Seven diseases cover 96% of the causes of this syndrome in many countries of the world, but some geographical variations have been observed. One example of these variations is amoebic liver abscess, present in 5 to 10% of Mexico City patients. Right upper quadrant pain is often present in amoebic liver abscess and acute cholecystitis. Thus, differential diagnosis of these two entities is difficult. Using discriminant analysis and "stepwise" procedures in 100 cases with cholecystitis and a similar number of patients with amoebic liver abscess, we found six variables (symptoms and signs with a significant chi square to distinguish between these two diseases. The symptoms and signs chosen were hepatomegaly, Murphy's sign, duration of pain greater than or equal to 48 hours, previous history of abdominal pain, dysentery, and facial pallor. These variables proved to be better than laboratory test results. With five of these variables it was possible to obtain an accuracy of 92%. Using six variables, if cases of tie (three variables present and three absent) were excluded, accuracy rose to 96%.

Abdomen, Acute↗
PubMedDate not supplied

Pyogenic liver abscess in pregnancy.

The first case of pyogenic liver abscess during pregnancy is described. Despite its rarity, this severe complication has to be considered when a febrile illness accompanied by upper abdominal pain and hepatomegaly occurs during pregnancy and puerperium. Diagnostic methods and treatment are suggested.

Adult↗
PubMed1986

Specific circulating immune complexes in amoebic liver abscess.

A micro enzyme-linked immunosorbent assay was used to detect the presence of amoebic antigen in polyethylene-glycol-precipitated circulating immune complexes (CIC). A cutoff dilution of greater than 1:160 for the precipitates was taken to be of clinical significance. Among the patients with amoebic liver abscess, 93% (14 of 15 confirmed cases) had indications of amoebic antigen in CIC. In 57% of the suspected cases of amoebic liver abscess, amoebic antigen could be detected in CIC. The specificity of the technique for the demonstration of specific amoebic antigen is indicated by the undetectable levels of amoebic antigen in CIC in serum samples from nine cases of nonamoebic hepatic diseases and 10 apparently healthy subjects. It is thus believed that the specific diagnosis of an individual case of amoebic liver abscess can be made by demonstrating specific amoebic antigen in CIC.

Antibodies↗
PubMed1995

Role of the Entamoeba histolytica cysteine proteinase in amebic liver abscess formation in severe combined immunodeficient mice.

Evidence from in vitro studies suggest that the Entamoeba histolytica cysteine proteinase plays a role in the tissue lysis and cytopathic effects seen in invasive amebiasis. We used affinity-purified antibodies against a recombinant E. histolytica cysteine proteinase to demonstrate that the proteinase is present extracellularly in amebic liver abscesses in mice with severe combined immunodeficiency (SCID mice). Treatment of E. histolytica trophozoites with specific cysteine proteinase inhibitor E-64 blocked or greatly reduced liver abscess formation at 48 h in SCID mice. Our study suggests an important role for a functional cysteine proteinase in amebic liver abscess formation.

Animals↗