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At least 595 records · Page 33Linked to original sources
PubMedDate not supplied

Distributing pattern of the bile duct of the caudate lobe on computed tomography with drip infusion cholangiography and its surgical significance.

BACKGROUND/AIMS: It is important to recognize the distribution of the bile ducts in the caudate lobe of the liver for the hepato-biliary surgery. To map the spatial relationship between the bile ducts and the liver parenchyma under physiological conditions, we performed an anatomical analysis of them using computed tomography combined with drip infusion cholangiography (DIC-CT). METHODOLOGY: We identified the bile ducts in the caudate lobe, which was divided into the Spiegel lobe, paracaval portion, and caudate process, with DIC-CT. We then investigated their number and confluence pattern in 132 patients without any abnormality in the hilar bile ducts. RESULTS: The mean number of the bile ducts in the caudate lobe was 2.68 per liver. In the Spiegel lobe, the branches drained into the left hepatic duct system in about 83%. The confluence of the paracaval branch was the left hepatic duct, right hepatic duct, and posterior segmental branch, all with the same frequency of approximately 30%. Almost all of the caudate process branches (92.4%) drained into the posterior segmental branch. CONCLUSIONS: DIC-CT is a useful method for the anatomical analysis of the intrahepatic bile ducts under physiological conditions, and we obtained novel and important findings for surgery.

Adult↗
PubMedDate not supplied

[Effect of contrast media on the rate of oxidation of NADP.H and NAD.H by rat liver microsomes].

The effect of roentgen-contrast media on the activity of the NADP'N and NAD'N-dependent electron-transport chains of the rats liver microsomes was studied. Bilignost, cardiotrast, triiotrast and triombrin are shown to lower the rate of the NADP'N oxidation by the rats' liver microsomes and have no effect (except for triiotrast) upon the rate of the NAD'N oxidation. It is presumed that the relative resistance of the NAD'N-specific flavoproteid is due to the presence of a hydrophobic layer impervious to the polar molecules of the contrast media.

Acetrizoic Acid↗
PubMed1978

[Use of contrast radiography in acute obstruction of the small intestine].

The authors believe that the contrast radiography of the small intestine in case of its obstruction should be used on strict indications only and only in patients with unclear clinical and roentgenological picture. When following the method strictly, the examination is safe for the patient, it may be stopped at any stage when evident symptoms, both clinical and roentgenological, of the obstruction appear.

Acute Disease↗
PubMedDate not supplied

[The effect of x-ray contrast agents on the concentration and size of immune complexes in the blood].

Bilignost, iodamide and triombrast were shown to increase the concentration and to decrease the size of the rat blood serum immune complexes in vivo and in vitro. A decrease of the size of immune complexes was also observed during angiography with the use of triombrast in humans. According to the relation to the action of roentgen contrast media on the concentration and size of immune complexes humans and rats can be divided in "sensitive" and "tolerant" ones.

Animals↗
PubMed1990

[New aspects of intolerance of the aqueous iodinated x-ray contrast medium, adipiodone--fatal interaction of adipiodone-Ultrabil with the immunomodulators Corynebacterium parvum (CP) and Shigella dysenteriae endotoxin (LPS)].

The authors assume a new type of interaction of the aqueous X-ray contrast substance type adipiodone (Ultrabil 50% Spofa) with immunomodulators of Corynebacterium parvum (CP) and the endotoxin of Shigella dysenteriae (LPS). The fatal type of interaction developed regularly as a result of the concurrent i.v. administration of the X-ray contrast substance adipiodone with the endotoxin of Shigella dys. (LPS) to laboratory animals (mice) which had five days previously a single dose of Corynebacterium parvum (CP). The effect of the interaction was evaluated using LD50 of adipiodone (Ultrabil Spofa) which in interaction with the immunomodulators of CP and LPS was identical as the dose used in diagnostic practice. The authors considered the possible development of "oxygen stress" as a consequence interacting processes and complement activation.

Adjuvants, Immunologic↗
PubMed1990

[The characteristics of the x-ray image of the uterus bicornis].

The results from a hysterographic study on women with bicornuate uterus are discussed. It is established that its frequency is 2.2% of 1623 performed hysterosalpingographies. A detailed analysis is made on the form and dimensions of the cornua [correction of corns], total isthmic part and cervical canal. Some metric parameters (height and width, sizes of the isthmus the an angle between the corns) are given with the purpose of greater precision of roentgenological interpretation.

Contrast Media↗
PubMed1990

[The results and tolerability of infusion cholegraphy using ioglycamide-85 (12.75 g meglumine salt in 75 ml) in comparison with the use of a hypotonic adipiodone solution (10 g meglumine salt in 100 ml)].

The quality of 96 infusion cholegraphies with isotonic Ioglycamide-85 solution and of 2,080 infusion cholegraphies with hypotonic adipiodone-50 gave equal images in 97% of the cases. Ioglycamide-85 caused side-effects in 15.6%, Adipiodone only in 1.5% of the cases. For improved compatibility of Ioglycamide and of new contrast media as Iotroxamide and Idoxamide the use of hypotonic solutions is recommended for infusion. Their concentration should be osmotically tolerated by the erythrocytes. For the prevention of liver necrosis by contrast media the amount of contrast medium should be limited to 10 g meglumine salt.

Adult↗
PubMed1988

Decrease of plasma prekallikrein and kallikrein inhibitors during intravenous phlebography.

Complex contact activation systems may have major involvement in side effects of i.v. contrast media. To investigate this, quantitative measurements of several factors (plasma prekallikrein, kallikrein inhibitory activity, haematocrit, alpha-2-macroglobulin, antithrombin III, alpha-1-antitrypsin and beta-thromboglobulin) were made before and after i.v. contrast phlebography in two groups of patients (each containing 21 patients) with no thrombosis, using a high- (meglumine iodamide) and a low-osmolality (ioxaglate) contrast medium. A statistically significant decrease in plasma prekallikrein was observed after the high-osmolality contrast medium, which is a sign of the activation of the kallikrein-kinin system and an indicator of the activation of the intrinsic coagulation. These events may play an important role in the adverse effects of contrast media.

Antithrombin III↗
PubMed1989

[Comparative evaluation of methods for the diagnosis of submucosal myomatous nodules].

The authors examined 33 women at fertile age with complaints of dysfunctional uterine bleedings, not affected by medicamentous therapy and absence of convincing data for changes in the gynecological status. Probatory curettage was made in 18 out of 33 women, but ultrasonic examination was made on the other 15 patients. We compared the obtained results with the data from hysterographic examination. It was established that the diagnosis of submucous nodules was established in 44.4% of women after the probatory curettage, while this was true only in 1/5 of the patients by the method of echography as in diagnostic respect the results were in direct dependence upon the size and location of myomatous nodules.

Adult↗
PubMedDate not supplied

[Transport of x-ray contrast media in isolated target and nontarget cells].

It was found that the accumulation of 125I-bilignost by isolated hepatocytes as target cells is mediated by the saturated and unsaturated systems. In thymocytes as non-target cells no saturated system of 125I-bilignost absorption was detected. 125I-triombrast transport in isolated hepatocytes and thymocytes takes place by usual diffusion.

Absorption↗
PubMed1989

[Use of a nonionic contrast medium (Omnipaque 350) in hysterosalpingography. A comparison with ionic contrast media].

The comparative adequacy was investigated of a nonionic contrast medium (iohexol) versus the ionic contrast medium usually employed in hysterosalpingography. The contrast radiologic features and the radiodiagnostic possibilities of both cm are definitely good. The nonionic contrast medium diffuses quickly and causes the uterine cavity to expand less than ionic contrast media do, thus allowing a better depiction of mucosal and/or parietal pathology. Moreover, nonionic cm allows tubal patency and peritoneal diffusion to be clearly demonstrated, particularly in uncertain cases. As compared to ionic cm, Iohexol did not cause any side effects, except for a mild discomfort. Our results lead us to suggest the use of nonionic contrast medium as the routine contrast medium in hysterosalpingography.

Adult↗
PubMed1989

[Effect of x-ray contrast substances on the complement system of rats].

The purpose of the work was to demonstrate the effect of radiographic contrast media (RCM) 50% bilignost, 76% triombrast, 80% iodamide-380 on the complement system in rats. It has been found that RCM cause alternative complement activation during incubation with the whole blood or serum in vivo and in vitro. The RCM effect value depends on the drug dose and increase in the order: triombrast iodamide bilignost. Different sensitivity of animals to the effect of RCM on the complement system has been shown.

Animals↗
PubMedDate not supplied

Adverse reactions to iotroxate at intravenous cholangiography. A prospective clinical investigation and review of the literature.

The number and type of adverse reactions to meglumine iotroxate at intravenous infusion cholangiography, performed one day prior to elective cholecystectomy, were recorded in a prospective investigation of 196 asymptomatic, anicteric patients. One hundred ml (50 mg I/ml) of contrast medium was infused over a period of 30 minutes. Only 2 minor (1%) and no severe or fatal reactions were noted. A review of the literature on the use of iotroxate in 2492 patients, including those in the present investigation, revealed a complication rate of 3.5 per cent (3.0% minor, 0.3% moderate and 0.2% severe reactions) at infusion of iotroxate (5.0-8.0 g I) over a period of 30 to 120 minutes. This compared favourably with the 5 per cent complication rate (4% minor, 0.5% moderate and 0.5% severe reactions) at infusion of iodoxamate and the 9 per cent complication rate (5% minor, 1% moderate and 3% severe reactions) at infusion of ioglycamide. Irrespective of the contrast agent used, the frequency of adverse reactions at infusion was found to be 3 times lower than when equal amounts (5.0-5.6 g I) of the same medium were injected. It is concluded that, at present, infusion of iotroxate in an amount which approximates to the transportation maximum of the liver is the least toxic way of performing intravenous cholangiography with an optimum filling of the bile ducts.

Adolescent↗