Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “FLORIDA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 595 records · Page 33Linked to original sources

Prevention of leucaena toxicosis of cattle in Florida by ruminal inoculation with 3-hydroxy-4-(1H)-pyridone-degrading bacteria.

Ruminal microorganisms in cattle at a Florida agriculture research station did not have the ability to detoxify leucaena by degradation of 3-hydroxy-4(1H)-pyridone (3,4,-DHP), but a DHP isomer (2,3-DHP) was degraded in some cattle. Cattle with microorganisms that degraded 2,3-DHP were mostly Senepol cattle imported from St. Croix, US Virgin Islands, where leucaena is an indigenous species. Hereford cattle at the research station in Florida generally did not degrade 3,4-DHP or 2,3-DHP. An experiment was conducted in which a pure culture of 3,4-DHP-degrading bacteria was inoculated into Hereford cattle (with ruminal fistula) grazing leucaena. The bacteria successfully colonized the rumen of recipient cattle and persisted through the following winter when there was no leucaena in the diet.

Animals↗

[Effect of lignin preparations and cultivation conditions on the ligninolytic complex of the fungus Pleurotus floridae, the wood white-rot pathogen].

Effect of various cultivation conditions and lignin preparations on the enzymes of ligninolytic enzyme complex of white-rot fungus Pleurotus floridae has been studied. The maximal Mn-peroxidase activity was revealed in the medium with low nitrogen content (1.2 mM); maximal values of cellobiose quinone oxidoreductase activity were observed in the media with high nitrogen content (7.2 mM); maximal values of laccase activity in the media with low content of glucose (2 g/l) during Pleurotus floridae cultivation in Kirk's stationary cultures have been shown. Employment of submerged cultivation under conditions of mycelium immobilization on polyurethane carriers allowed us to increase laccase activity twice as compared with cultivation in small stationary cultures, while had the crucial effect on the Mn-peroxidase activity. The selective effect of the studied lignin preparations on the components of ligninolytic complex and their isoenzymes has been stated. The dependence of laccase and Mn-peroxidase activities on high and low-molecular weight fractions balance in lignin preparations has been established.

Carbohydrate Dehydrogenases↗

Hospitalization, inpatient physical therapy and institutionalization after hospital discharge of prostate cancer patients in south Florida.

PURPOSE: Explaining survival variation in prostate cancer requires the identification of new predictive factors, of which physical function is attractive hypothetically. To understand physical dysfunction in prostate cancer better, we examined medical claims. Our aims were to describe the consumption of inpatient resources, examine the association of physical therapy with institutionalization after hospital discharge and determine the association of disease stage with frequency of hospitalization, inpatient physical therapy and discharge to a skilled nursing facility. MATERIALS AND METHODS: We used 1994 Medicare claims for patients in South Florida who had prostate cancer. To examine the association of disease stage with use of health services, we inferred disease stage from stage specific treatment. Multiple linear regression was used to examine the interaction of inferred disease stage with health services while adjusting for age. RESULTS: A total of 22,279 residents of South Florida a mean of 78.3 years old with prostate cancer billed Medicare in 1994. Of these patients 2,507 were admitted to a hospital 4,606 times, resulting in total charges of $70 million. Many claims indicated physical dysfunction, including 1,896 charges for physical therapy, which was associated with more institutionalization after hospital discharge. Disease stage and patient age were individually associated with the frequency of hospitalization, inpatient physical therapy and discharge to a skilled nursing facility. CONCLUSIONS: Inpatients with prostate cancer have substantial stage dependent physical dysfunction. If the hypothesized interaction of physical dysfunction with mortality is confirmed in prospective studies and outpatient settings, theoretically the door will have been opened to new interventions for prolonging survival in patients with prostate cancer.

Aged↗

Femoropopliteal bypass is not a generic procedure: a survey of the practice patterns of the Florida Vascular Society.

The purpose of this study was to evaluate whether surgeons perform femoropopliteal bypass using standard or dissimilar methods. A questionnaire was mailed to all members of the Florida Vascular Society, which consists of 83 board-certified vascular surgeons. Fifty-three responded (62%). Eighty-one questions covered aspects of the intraoperative and postoperative technical details usually involved in performing femoropopliteal bypass. Surgeons performed between 10 and 80 (mean 38) femoropopliteal bypasses per year. Only seven (13%) surgeons were aware of their patency rates. The results of this study showed that surgeons are largely unaware of their patency rates. When the variables used in this study were considered, no two surgeons performed the procedure in an identical manner. This variation in practice pattern may account for the discrepancy in reported patency rates for femoropopliteal bypass.

Angiography↗

SEROLOGICAL EVIDENCE OF ARBOVIRUS INFECTION IN THE SEMINOLE INDIANS OF SOUTHERN FLORIDA.

A serological survey of the Seminole Indians in south Florida for evidence of exposure to arbovirus infection indicated not only past infection with the recognized North American encephalitis viruses-a high incidence for St. Louis encephalitis-but exposure to a Bunyamwera group agent and to Venezuelan equine encephalitis virus, activity of which had not been previously recognized north of Panama.

Animals↗

VENEZUELAN EQUINE ENCEPHALITIS VIRUS FROM SOUTH FLORIDA.

Venezuelan equine encephalitis virus was isolated three times from the Culex (Melanoconion) species of mosquitoes collected in south Florida in June, July, and October, 1963. Specific antibody was present in 16 of 28 Peromyscus gossypinus (cotton mice) and 3 of 16 Sigmodon hispidus (cotton rats) sampled from one of the infected sites in January 1964.

Animals↗

First case of bioterrorism-related inhalational anthrax in the United States, Palm Beach County, Florida, 2001.

On October 4, 2001, we confirmed the first bioterrorism-related anthrax case identified in the United States in a resident of Palm Beach County, Florida. Epidemiologic investigation indicated that exposure occurred at the workplace through intentionally contaminated mail. One additional case of inhalational anthrax was identified from the index patient's workplace. Among 1,076 nasal cultures performed to assess exposure, Bacillus anthracis was isolated from a co-worker later confirmed as being infected, as well as from an asymptomatic mail-handler in the same workplace. Environmental cultures for B. anthracis showed contamination at the workplace and six county postal facilities. Environmental and nasal swab cultures were useful epidemiologic tools that helped direct the investigation towards the infection source and transmission vehicle. We identified 1,114 persons at risk and offered antimicrobial prophylaxis.

Anthrax↗

Rocky Mountain spotted fever and jaundice. Two consecutive cases acquired in Florida and a review of the literature on this complication.

Rocky mountain spotted fever is increasing in Florida, a state that has had few cases in the past. The typical clinical illness has been well described, but jaundice has been rarely reported. In two patients with illnesses resembling leptospirosis, jaundice appeared on the sixth and ninth day of illness, and peak bilirubin levels were between 7 and 9 mg/100 ml. Liver biopsy specimen from one patient showed a nonspecific hepatitis. Hemolysis and renal dysfunction may have contributed to the production of jaundice in these patients. Fourteen instances of jaundice were reported in 43 autopsied cases as of 1941, but since that time only rare mention of jaundice has been made.

Child↗

Mortality and community mental health. The Alachua County, Florida, mortality study.

This study reports the results of a household survey and search of death certificates that show a relationship between depression, anxiety, and subsequent mortality. It is part of an effort to develop practical epidemiologic techniques for continuous assessment of community mental health. Use is made of the population attributable mortality rate, estimated from a comparison of the prevalence of a given factor in life and at death. The study estimated attributable mortality prospectively by following up participants in a mental health survey of Alachua County, Florida, for up to four years. Of eight mental scales examined, five (mood, depression, somatic symptoms of anxiety, the Health Opinion Survey, and selected psychopathologic symptoms) showed significant association of scores with community mortality. The data suggest linkages of mental factors to mortality of an order of magnitude sufficient to warrant consideration of these factors as leading causes of death.

Anxiety Disorders↗

Psychiatric and substance use disorders in South Florida: racial/ethnic and gender contrasts in a young adult cohort.

BACKGROUND: Prevalence rates of psychiatric and substance use disorders among young adults in South Florida are presented. Unique aspects of the study include the large sample size, its ethnic diversity, and the fact that a substantial proportion of Hispanic participants were foreign born. METHODS: This study builds on a previous cohort study of students who entered middle school in 1990. A random subsample of this representative cohort (N = 1803) was interviewed between 1998 and 2000 when most were between 19 and 21 years of age. Disorders were assessed through computer-assisted personal interviews utilizing the DSM-IV version of the Michigan Composite International Diagnostic Interview. RESULTS: More than 60% of the sample met lifetime criteria for 1 or more study disorders, and 38% did so within the preceding year. Childhood conduct and major depressive and alcohol abuse disorders were the most prevalent. Although rates of affective and anxiety disorders in females were double that in males, this gender difference disappeared when attention-deficit/hyperactivity disorder, conduct disorders, and antisocial personality disorders were also considered (46.6% vs 45.7% for females vs males, respectively). Substantially lower rates were observed among African Americans for depressive disorders and substance abuse and dependence. Among Hispanics, rates tend to be lower among the foreign-born in comparison with their US-born counterparts, particularly for the substance disorders. CONCLUSIONS: The documented presence of psychiatric and substance disorders in middle and high school populations emphasizes the importance of prevention efforts in school settings. Research on the origins of ethnic and nativity differences is called for.

Adolescent↗

Acute hemorrhagic conjunctivitis Investigation of a large-scale community outbreak in Dade County, Florida.

An outbreak of acute hemorrhagic conjunctivitis (AHC) due to enterovirus type 70 occurred in Dade County, Florida, from September to December 1981. Younger age groups, members of larger households, and the poor were at significantly greater risk of acquiring AHC than others in the community. Schoolchildren were most likely to introduce AHC into the household. After exclusion of all affected children from school, there was a dramatic reduction in reported cases, with attack ratesups, members of larger households, and the poor were at significantly greater risk of acquiring AHC than others in the community. Schoolchildren were most likely to introduce AHC into the household. After exclusion of all affected children from school, there was a dramatic reduction in reported cases, with attack ratesups, members of larger households, and the poor were at significantly greater risk of acquiring AHC than others in the community. Schoolchildren were most likely to introduce AHC into the household. After exclusion of all affected children from school, there was a dramatic reduction in reported cases, with attack rates declining more rapidly for school-aged children than for other age groups. Although AHC spread readily among family members, a retrospective study of 124 affected households showed an association between lower attack rates and simple hygienic measures. Should outbreaks of AHC recur, measures to reduce transmission should include exclusion of affected schoolchildren and educating the public about hygienic precautions.

Acute Disease↗

An updated mortality follow-up study of Florida phosphate industry workers.

We have added 14 years of mortality follow-up to a previously studied cohort of 18,446 white and 4,546 nonwhite male workers in the Florida phosphate industry. Follow-up was performed for the years 1949-1992. Based on comparisons with national rates, lung cancer standardized mortality ratios (SMR) were slightly elevated among white (SMR = 1.19; 354 observed) and nonwhite males (SMR = 1.13; 105 observed). However, no lung cancer excesses were found relative to local county rates (SMR = 0.98 for whites, SMR = 0.94 for nonwhites). Based on internal analyses of lung cancer mortality, using Poisson regression modeling, there were no associations of lung cancer with cumulative exposures to total dust, silica, or acid mists. There were weak trends of lung cancer risk with alpha and gamma radiation among white males, but no associations with radiation in nonwhites. No relation was found between acid mist exposures and laryngeal cancer. We conclude that there have not been large excesses of lung cancer or other diseases related to workplace exposures in this cohort.

Acids↗

Non-Hodgkin's lymphoma of the head and neck: a 30-year experience at the University of Florida.

BACKGROUND: Outcome in previously untreated patients with non-Hodgkin's lymphoma of the head and neck needed to be assessed. METHODS: A retrospective review was performed of 79 patients with stage I or II non-Hodgkin's lymphoma of the head and neck treated between 1964 and 1994 with radiotherapy (RT) or combined modality therapy (CMT) at the University of Florida. Freedom from relapse, cause-specific survival, and absolute survival were analyzed by the Kaplan-Meier method. Patterns of failure were defined, and the relationship between dose and infield recurrence was studied. Histology was classified as low grade or intermediate/high grade. RESULTS: At 10 years, absolute survival for patients with low-grade lymphoma treated with RT was 45%; absolute survival for patients with intermediate/high-grade lymphoma was 41% for those treated with RT and 57% for those who received CMT. Twenty-seven patients had a recurrence of lymphoma after initial treatment. Twenty patients (74%) had recurrences outside the radiation treatment field; 90% of these failures were in predictable sites that would be included in comprehensive lymphatic irradiation fields (Waldeyer's ring, mantle, and whole abdomen). No clear dose response was observed. Multivariate analysis showed that patients with tumors <5 cm in diameter had improved cause-specific survival, absolute survival, and freedom from relapse compared with patients with tumors > or = 5 cm in diameter. CONCLUSIONS: Patients with non-Hodgkin's lymphoma in the head and neck with tumors > or = 5 cm in diameter appear to have a worse prognosis than those with smaller tumors. The patterns of failure suggest that initial treatment with comprehensive lymphatic irradiation fields could potentially eliminate the majority of treatment failures.

Adult↗

Output efficiency of health maintenance organizations in Florida.

We use data envelopment analysis (DEA) to measure the relative technical efficiencies of 28 HMOs licensed to practice in the State of Florida in the autumn of 1994. Health care output measures used in the analysis are number of commercial, Medicare and Medicaid members enrolled in each plan. Inputs to the model are capital assets, total expenditures on the provision of medical services and administrative expenses. We find differences in HMO efficiency scores and loss ratios (defined as the ratio of expenses on the provision of medical services to the total expenses incurred by the organization) across individual plans. Differences in efficiency measures across model type (staff, IPA, combination) and ownership types (for-profit, not-for-profit) are small but significant: staff models and for-profits are more efficient. In a multivariate model, we also find that large HMOs are more efficient and HMOs with Medicaid patients are significantly less efficient than other HMOs.

Ambulatory Care↗

Occupation and the high risk of lung cancer in Northeast Florida.

A case-control study involving interviews with 321 male patients with lung cancer and 434 controls, or their next of kin, was undertaken to identify reasons for the high lung cancer mortality along the northeast coast of Florida. In Duval county (Jacksonville), the age-adjusted rate for lung cancer, 1970-1975, among white males was the highest of all urban counties in the United States. Increased risks on the order of 40-50% were associated with employment in the shipbuilding, construction, and lumber/wood industries, particularly among workers with reported exposures to asbestos or wood dust. Excess risks were also linked to fishing and forestry occupations, although the numbers of cases involved were small. Occupational factors did not appear to fully account for the area-wide excess of lung cancer, but no evidence was found to implicate smoking habits, migration patterns, or diagnostic and reporting practices as factors responsible for the exceptional mortality rates.

Aged↗

Cancer among Haitians in Florida.

Data on cancer rates from West Indian populations are scarce, and to the authors' knowledge there are no published data on cancer rates and distributions among Haitians. Proportional distributions of cancers among three groups of patients living in Florida were compared: Haitian born blacks, United States born blacks, and non-Haitian Caribbean born blacks. The incidence rate of cancer of the cervix among the Haitian and United States born black groups was also compared. Increased rates of certain malignancies associated with viral infection or immunodeficiency were found in the Haitian group. These tumors were hepatocellular carcinoma, nasopharyngeal carcinoma, reticulum cell sarcoma, Kaposi's sarcoma, and carcinoma of the uterine cervix. The age-adjusted incidence rate of carcinoma of the cervix was especially high among Haitian women even with a liberal estimate of the female Haitian population from whom the cases were drawn. Except for cancer of the cervix, the numbers of cancers of interest were small, and age-adjusted incidence rates were not calculated. Continued epidemiological study of larger numbers of patients is needed to evaluate these findings further.

Adult↗

Epidemiology of cancer among Hispanic males. The experience in Florida.

To assess cancer incidence among Hispanic males in Dade County, Florida, data were analyzed from the statewide tumor registry. For all cancer sites (combined), the age standardized rate among Hispanic males was 308.75 cases per 100,000 person-years, compared with 349.55 among non-Hispanics (standardized rate ratio [SRR] = 0.88; 95% confidence interval [CI] = 0.84-0.93). Hispanics experienced significantly greater rates of cancers of the larynx (SRR = 1.58; 1.19-2.09), thyroid (SRR = 3.12; 1.18-8.26), and gallbladder (SRR = 5.45; 1.55-19.15), compared with non-Hispanics, but significantly lower rates of testicular cancer (SRR = 0.17; 0.09-0.37), melanoma (SRR = 0.20; 0.12-0.34), esophagus (SRR = 0.52; 0.49-0.55), stomach (SRR = 0.61; 0.43-0.87), pancreas (SRR = 0.65; 0.45-0.94), kidney and renal pelvis (SRR = 0.68; 0.48-0.97), colon (SRR = 0.79; 0.67-0.94), lung (SRR = 0.82; 0.73-0.94), and Kaposi's sarcoma (SRR = 0.03; 0.00-0.25). These data suggest that Dade Hispanic males have not experienced the cancers traditionally elevated among US Latinos, or those common among non-Hispanics.

Adult↗

The epidemiology of cancer among Hispanic women. The experience in Florida.

To explore cancer incidence among Hispanic women living in Dade County, Florida, data were analyzed from the statewide cancer registry. For all but three sites, Hispanics had lower rates of the 15 most prevalent cancers than non-Hispanics. However, higher rates of cancer among Hispanics were noted for cancers of the gallbladder, liver, and heart and soft tissue. Subgroups of women had significantly higher rates of cervical cancer and thyroid cancer. Lower rates among Hispanics were observed for cancers of the esophagus, vagina, breast, colon, buccal cavity and pharynx, and malignant melanoma. These data suggest that most cancer sites traditionally higher among US Latino women were not higher among Dade Hispanics, and that sites more common among non-Hispanics have not yet shown an increased incidence among Hispanic women in Dade County.

Aged↗