Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “FIBROMA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 595 records · Page 33Linked to original sources
PubMed1992

Central odontogenic fibroma, WHO type. A report of three cases with an unusual associated giant cell reaction.

Three cases of central odontogenic fibroma, WHO type, that exhibited a prominent giant cell granuloma-like histopathologic component are described in this report. All three lesions occurred in women, and all were located in the mandibular premolar-molar region. One lesion recurred after conservative excision, and the recurrence displayed the two histologically distinct tissues of the original lesion. The authors think that this pathologic process does not represent a "collision lesion" but, instead, is a unique presentation of a central odontogenic fibroma, WHO type.

Adolescent↗
PubMed1987

Chondromyxoid fibroma of the petrous-sphenoid junction.

A case of primary chondromyxoid fibroma of the petrous and sphenoid bones extending into the posterior clinoid process, sella, and cavernous sinus in a 26-year-old man is reported. The presence of this tumor was heralded solely by the progressive paresis of the abducens nerve. The occurrence of this tumor is exceedingly rare, and to our knowledge, this is the first report of a primary chondromyxoid fibroma in the parasellar region. The natural history of this tumor, its pathologic diagnosis, and its treatment will be discussed with reference to this unusual case.

Adult↗
PubMed1993

Chromosome abnormalities in cementifying fibroma.

Cementifying fibroma is the most frequent benign fibro-osseous odontogenic tumor. We found chromosome abnormalities in a second case of this type of benign tumor. The chromosome changes in both cases are different. The chromosome bands involved in our case have not been described before in any benign fibroma so far reported.

Adolescent↗
PubMed1986

Ameloblastic fibroma of the mandible.

A case of an ameloblastic fibroma in the mandible is presented. The ameloblastic fibroma is a benign neoplasm belonging to the group of mixed odontogenic tumours. Enucleation is the treatment of choice. Recurrence of the tumour is very rare, but follow up is necessary. Fewer than 75 cases are described in the literature. An additional case is presented with radiographic signs of calcification which could not be identified on histopathological examination.

Adult↗
PubMed1986

Chondromyxoid fibroma of the proximal phalanx. A tumour that may be confused with chondrosarcoma.

Chondromyxoid fibroma is a rare benign tumour of chondral origin. The diagnosis is difficult, but as Jaffe emphasized, "its recognition is of some importance in that pathologically it may be mistaken for sarcoma and, as such, treated more radically than is necessary" (Jaffe, 1948). Salzer (1965) found only 136 cases in the world literature since 1948 when Jaffe defined the criteria for their histological diagnosis. Only six cases of chondromyxoid fibroma have been reported involving the hand (Frank, Rockwood, 1969; Zatyepin, Klimova, Lipkin, Perety, 1979).

Bone Neoplasms↗
PubMed1985

Ameloblastic fibroma in an infant.

A case of ameloblastic fibroma associated with a hypoplastic lesion in an unerupted deciduous central incisor is presented. Whether this case provides new evidence concerning the time and source of origin of the ameloblastic fibroma is open to debate, but the possible implications may be worthy of further study.

Diagnosis, Differential↗
PubMed1986

Recurrent cementifying fibroma.

A case of recurrent cementifying fibroma in an adolescent girl, necessitating repeated surgery, is reported. The multifocal nature of the tumor in the third recurrence, seven years after the initial surgery, leads to speculation as to the possible multifocal development of cementifying fibroma. Histologic assessment is of no value in predicting the behavior of this tumor, but radical surgery does not appear to be justified, even for tumors that have recurred. In the present case, however, partial mandibulectomy was ultimately performed, because, despite repeated conservative surgery, the patient had recurrences that caused pain and gross deformity.

Adolescent↗
PubMed2006

Cementifying fibroma of the frontal bone: a case report.

Cementifying fibromas are rare fibro-osseous tumours that are usually found in the jaws. We report a 10-year-old boy who presented with a mass in the frontal bone causing frontal bossing and proptosis. The preoperative diagnosis was not clear despite computed tomographic and magnetic resonance imaging. The lesion was resected completely and found to be a cementifying fibroma. It was reconstructed at the same operation and he made a good recovery with no sign of recurrence.

Child↗
PubMed2005

Chondromyxoid fibroma of the zygoma: a case report.

Chondromyxoid fibroma is a rare benign tumour of chondral origin. It usually involves the long bones of the lower extremity, whilst involvement of craniofacial skeleton is extremely unusual. The second case of chondromyxoid fibroma of the zygoma described in literature is presented and the surgical resection of the lesion with tumour-free margins as the key factor for avoiding local recurrence of this tumour is emphasised.

Calcinosis↗
PubMed2006

Enamel dysplasia with odontogenic fibroma-like hamartomas: review of the literature and report of a case.

This article reports on a case presenting with a rare syndrome characterized by enamel dysplasia and multiple unerupted teeth with large solid fibrous pericoronal lesions manifesting with odontogenic fibroma-like features. Our case shows in addition to these findings an anterior open bite malocclusion and gingival overgrowths. These overgrowths exhibit the microscopic features of the multiple pericoronal odontogenic fibroma-like lesions that appear to be the hallmark of this syndrome. This unusual case brings the total number documented in the literature to 5, all of which were reported from South Africa.

Black People↗
PubMed1982

Chondromyxoid fibroma of bone.

Chondromyxoid fibroma is a rare benign neoplasm of bone with a predominant incidence in the second and third decades of life. The commonest site is on either side of the knee joint. There is often endosteal sclerosis, well-defined scalloping and other benign features, although the cortex may be destroyed. It is commonly eccentric and rarely shows radiological evidence of calcification. The radiological features of 31 histologically confirmed cases are described and the literature is reviewed. Chondromyxoid fibroma may be mistaken radiologically for other lesions, particularly when it does not occur in a characteristic site; the differential diagnosis is discussed.

Adolescent↗
PubMed1997

Chondromyxoid fibroma of the temporal bone.

BACKGROUND: Chondromyxoid fibromas are benign neoplasms comprising approximately 0.5% of primary bone tumors. The occurrence of this tumor in the skull is extremely rare, with only four previously reported cases involving the temporal bone and a total of 17 cases with intracranial involvement. CASE DESCRIPTION: We describe the case of a 22-year-old man who experienced a 1-year history of headaches with progressive ear pain and mild hearing loss. Computed tomography and magnetic resonance imaging of the head demonstrated an extraaxial tumor arising from the left temporal mastoid region. A craniotomy was performed and the tumor resection required extensive drilling of the temporal bone. Grossly, the tumor consisted of a firm semigelatinous myxomatous tissue containing multiple areas of calcification and was histologically consistent with chondromyxoid fibroma. CONCLUSIONS: Complete resection is the goal of surgery. Recurrence rates of 7% to 27% have been reported, dependent on the degree of initial resection. Radiation is not recommended because of the potential for sarcomatous conversion. Reoperation may be indicated for symptomatic recurrence.

Adult↗
PubMed1998

Cytogenetic analysis of a scapular chondromyxoid fibroma.

Chondromyxoid fibroma (CMF) is a rare cartilaginous tumor of bone. It typically presents in the lower extremities of young males. Cytogenetic analysis of two chondromyxoid fibromas has been previously reported. We studied a scapular CMF from an 11-year-old female by cytogenetic and molecular cytogenetic methods and found an unbalanced reciprocal translocation between the short arm of chromosome 3 and the long arm of chromosome 6. In this translocation, several bands from chromosome 3 (3p12, 3p13, 3p14, 3p21) are lost and several bands on chromosome 6 (6q21, 6q22, 6q23) appear rearranged. Two known cartilage-related genes are located in the regions affected by this unbalanced rearrangement: the type X collagen gene (COL10A1) located at 6q21-q22 and the parathyroid hormone/parathyroid hormone-related peptide receptor gene (PTH/PTHrP) located at 3p21.1-p22. These genes function to control growth and maturation of endochondral bone, the site of origin of cartilaginous tumors.

Bone Neoplasms↗
PubMed1998

Congenital ameloblastic fibroma in association with oculoauriculovertebral spectrum.

Although orodental anomalies have been reported to occur in patients with oculoauriculovertebral spectrum, no previous publications in the English literature have been located that describe an ameloblastic fibroma in a patient with this condition. This report presents a 15-month-old female monozygotic twin with concomitant oculoauriculovertebral spectrum and a congenital ameloblastic fibroma of the mandible. A theory linking the pathogenesis of the two conditions is also raised.

Diseases in Twins↗
PubMed1979

Ameloblastic fibroma and its sarcomatous transformation.

A case of ameloblastic fibroma, and one of its more aggressive variety, the ameloblastic "fibrosarcoma", are presented. The clinical and morphologic differences are discussed. In our opinion, ameloblastic "fibrosarcoma" is a semimalignant tumor. Therefore we propose "proliferating ameloblastic fibroma" as a more appropriate designation.

Adolescent↗
PubMed2003

Cementifying fibroma in the ethmoidal sinus extending to the anterior cranial base in an 11-year-old girl: a case report.

A case of an 11-year-old female with cementifying fibroma in the ethmoidal sinus extending to the anterior cranial base was presented. She complained of slowly progressive nasal obstruction and anosmia. Magnetic resonance imaging (MRI) revealed a tumor in both ethmoidal and sphenoidal sinuses and nasal cavity. Although a tumor reduction surgery was attempted through a transnasal approach, tumor size increased gradually and right exophthalmos subsequently appeared. The pathological diagnosis was cementifying fibroma of the nose. Total tumor removal was consequently accomplished through the intracranial anterior transbasal approach. The surgical approach should be selected according to the site and expansion of the lesion in individual patients.

Child↗
PubMed1999

Chondromyxoid fibroma of skull base: a tumour prone to local recurrence.

Chondromyxoid fibroma of the skull base is extremely uncommon. Sometimes involvement of the nasal cavity may occur and the patients may present with nasal symptoms. The biological behaviour of this tumour has not been well studied, primarily because of the limited number of reported cases and the short duration of follow-up. We report a histologically confirmed case of chondromyxoid fibroma of the skull base that recurred repeatedly over a 10-year period after the initial operation. Histologically it showed identical morphology to the original tumour with no evidence of histological progression or dedifferentiation. Ultrastructurally, the spindle tumour cells in the fibromyxoid area showed dual chondroblastic and fibroblastic differentiation, suggesting that these spindle fibroblastic cells and the better differentiated chondroid cells were of the same cell type with different histological morphology.

Child↗