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A prospective analysis of fenestrated endovascular grafting: intermediate-term outcomes.

PURPOSE: To assess the intermediate-term outcomes following fenestrated grafting for juxtarenal aneurysms. MATERIALS AND METHODS: A prospective trial was conducted on patients with short proximal necks, who were considered to be high-risk for open repair and unacceptable for conventional endovascular repair. Devices were designed from reconstructed CT data. Follow-up studies included CT, duplex ultrasound, and KUB and occurred at hospital discharge, 1, 6, and 12 months and annually thereafter. RESULTS: One hundred and nineteen patients were treated (2001-2005). Mean age and aneurysm size were 75 years and 65 mm, respectively, and 82% were male. A total of 302 visceral vessels were inferior to the fabric seal (a mean of 2.5 vessels per patient), with the most common design incorporating two renal arteries and the SMA (58%). All prostheses were implanted successfully without any acute visceral artery loss. The mean follow-up was 19 months (0-42 months). One patient died within 30 days of device implantation. Kaplan-Meier estimates of survival at 1, 12, 24, and 36 months are 0.99, 0.92, 0.83 and 0.79. There were no ruptures or conversions. Pre-discharge imaging noted 11 type I and type III endoleaks. The 30-day endoleak rate was 10% (all type II). Aneurysm sac size decreased (>5 mm) in 51, 79 and 77% at 6, 12 and 24 months, respectively. One patient had sac enlargement within the first year, associated with a persistent type II endoleak. In-stent stenoses occurred in 12 renal arteries and one SMA. Six renal arteries and the SMA stenosis were treated and two renal stenoses are awaiting treatment. Ten of 231 stented renal arteries occluded (three prior to discharge), one of which was recanalized. One component separation was treated with an extension at 2 years. CONCLUSIONS: The placement of endovascular prostheses with graft material incorporating the visceral arteries is safe and appears to be effective at preventing rupture. Continued follow-up to assess the long-term benefit, aneurysm sac behavior and effect of stenting upon the visceral ostia remains critical.

Aged↗

Catheter closure of tube graft fenestration in extracardiac Fontan operation.

As the extracardiac Fontan operation evolves, a reliable method for creating and subsequently closing communications between the systemic and pulmonary venous chambers would become useful. We describe a simple and safe technique of fenestration amenable to coil occlusion, which can be carried out in most cardiac catheterization laboratories.

Abnormalities, Multiple↗

Microsurgical keyhole middle fossa arachnoid cyst fenestration.

Microsurgical keyhole fenestration is a safe and effective surgical procedure for the treatment of middle fossa arachnoid cysts. This procedure can be performed with minimal morbidity through a keyhole craniotomy. Patient selection is crucial, as is knowledge of the surgical anatomy. We provide a detailed description of the technique, with Illustrations of the key aspects of the procedure.

Arachnoid Cysts↗

Endovascular management of juxtarenal aneurysms with fenestrated endovascular grafting.

PURPOSE: To evaluate the technical feasibility and short-term results of juxtarenal aneurysm repair with an endovascular graft that incorporated the visceral aortic segment with graft material. METHODS: Patients were studied prospectively after the implantation of an endovascular device with graft material extending proximal to the renal arteries, variably incorporating the superior mesenteric and celiac arteries. All patients were deemed to be high risk with respect to open surgical repair and had compromised proximal neck anatomy. Proximal neck lengths were <or=10 mm, or <or=15 mm with a challenging morphology (funnel shape or extensive thrombus). Fenestrations within the graft material were customized to accommodate visceral and renal vessels on the basis of computerized tomography (CT), angiography, or intravascular ultrasound data. Selected visceral ostia were protected with balloon-expandable stents after partial endograft deployment. All patients were evaluated with CT and kidney, ureters, and bladder x-ray at discharge and at 1, 6, and 12 months. Visceral duplex scan studies were performed at 1, 6, and 12 months. RESULTS: A total of 22 patients were enrolled in the study. Sixteen patients had short proximal necks (3-10 mm), and six had compromised necks of 10 to 15 mm in length. Endograft design included bifurcated (20) and tube (2) systems. All prostheses were implanted successfully without the acute loss of any visceral arteries. A total of 58 visceral vessels were incorporated (mean, 2.6 per patient) and most commonly included both renal arteries and the superior mesenteric artery. The mean follow-up was 6 months. There were no deaths within 30 days and no aneurysm-related deaths during the follow-up period. Two early (<30 days) and two late secondary interventions were performed, inclusive of two visceral artery stenoses detected with duplex scanning. The 30-day endoleak rate was 4.5%. The aneurysm sac decreased greater than 5 mm in 53 % of patients at 6 months and three of four patients at 12 months. Three patients developed renal insufficiency, only one of which required temporary hemodialysis. CONCLUSIONS: The placement of an endovascular prosthesis with graft material that incorporates the visceral arteries is technically feasible. The occurrence of endoleaks appears to be relatively low. The increased sealing and fixation zones in this patient population should limit the late development of proximal endoleak or migration; however, this situation will require more patients and extended follow-up.

Aged↗

Aortic fenestration for chronic aortic dissection type B complicated by transient ischemic attacks of spinal cord.

Spinal cord injury is a rare complication in patients with aortic dissection. The extrinsic arterial supply to the spinal cord, diminishing caudally, often becomes critically dependent on the great radicular artery (GRA) of Adamkiewicz at the thoracolumbar spine. There are no prior reports of spinal injury or ischemia caused by chronic aortic dissection. We report on a 51-year-old patient with chronic type B dissection of the aorta from below the subclavian takeoff through the iliac arteries, presented with multiple episodes of transient (1 to 5 minutes) spinal ischemic attacks, entailing sudden loss of motor and sensory functions in both legs, with collapse of the patient on the ground. GRA imaging acquired with 64-channel computed tomography angiography enabled aortic fenestration from T11 to L1, performed with supraceliac aortic cross-clamping (T8 to L2) via thoracoabdominal access. We critically appraise the pertinent literature.

Aortic Dissection↗

Fixative method of carotid shunt using a Sugita's fenestrated aneurysm clip as a device in carotid endarterectomy technical note.

BACKGROUND: Difficulty for distal exposure of the ICA is sometimes encountered during CEA. A carotid shunt is used to maintain sufficient cerebral blood flow during CEA but requires fixative materials, such as a string or a metallic ring, which often restrict the operative field, especially that of the distal ICA. METHODS: Here, we describe a novel technique for carotid shunt fixation using a unique fixative device in CEA. In the method presented here, the carotid shunt is fixed with an inflated balloon and a conventional vascular tourniquet proximally, but distal fixation is achieved using a Sugita's fenestrated clip that catches the mid portion of the carotid shunt and surrounding tissue. RESULTS AND CONCLUSION: The device prevents the distal carotid shunt slipping out of the distal ICA. The present method allows mobilization of the shunt position during CEA and facilitates far-distal exposure of the ICA.

Brain Infarction↗

Fenestrated sheen macular dystrophy.

We examined a family with fenestrated sheen macular dystrophy. The red macular lesions were strikingly apparent in the propositus and more subtle in one affected cousin. Pronounced macular retinal pigment epithelial disruption or mottling was present in the father of the propositus, who also had markedly reduced electroretinogram rod and cone responses. The extent of electroretinogram amplitude reduction indicates abnormal function of the peripheral retina in addition to the clinically evident macular changes. Affected family members showed peripheral retinal pigment epithelial granularity. Central visual acuity remained normal despite the presence of macular lesions.

Adult↗

Fenestrated arterial switch operation: surgical approach to an unusual transposition of the great arteries complex.

Transposition of the great arteries with intact ventricular septum and aortopulmonary window is an extremely rare anatomic combination, having been reported just twice previously. Other authors performed a physiologic repair, because the combination was considered unsuitable for an anatomic repair. We describe the case of a 26-day-old baby with such anatomy who was successfully treated with an arterial switch operation. A 4 mm fenestration at atrial level was made for a smoother postoperative course.

Aorta, Thoracic↗

Preoperative fenestration for type A acute aortic dissection with mesenteric malperfusion.

We report a case of a 71-year-old man presenting with acute type A aortic dissection and mesenteric ischemia due to extension of the intimal flap to the mesenteric artery. Because of the severity of the abdominal symptoms, surgical correction of the ascending aorta was delayed. Preoperative percutaneous fenestration was performed successfully, allowing ascending aortic replacement 6 days later. Transverse colon stenosis secondary to preoperative ischemia occurred in the postoperative course. The patient was discharged from hospital with normal intestinal transit 72 days later.

Aged↗

Stent-graft placement combined with percutaneous fenestration for the treatment of aortic dissection in a patient at risk of developing renal ischemia.

A 51-year-old man, suffering from an aortic dissection with the entry tear in the descending thoracic aorta, underwent replacement of the ascending aorta and aortic arch with resection of the entry tear. Although the false lumen of the descending thoracic aorta was thrombosed after surgery, redissection developed in the descending aorta 2 months later. Percutaneous fenestration was performed before stent-grafting because it was judged that there was a significant risk of left renal ischemia. Entry closure with a stent-graft was performed successfully and no renal ischemia developed. The patient is doing well at 1 year after the procedure.

Anastomosis, Surgical↗

Transcatheter closure of an extracardiac Fontan fenestration.

As the extracardiac Fontan operation evolves, a reliable method for creating and subsequently closing communications between the systemic and pulmonary venous chambers would be useful. We describe a surgical technique for creating this "fenestration" and a complementary transcatheter technique that allows safe and reliable closure of these communications regardless of size and position.

Anastomosis, Surgical↗

Fenestrated felt facilitates anastomotic stability and safety in "off-pump" coronary bypass.

Metal stabilizing devices used in beating heart surgery, although largely effective, occasionally slip or cause lacerations of epicardial veins or myocardium, resulting in blood loss that requires time-consuming corrective maneuvers. The use of a fenestrated felt as a cushion in conjunction with the stabilizers eliminates slipping and/or trauma, thus facilitating coronary anastomoses on the beating heart.

Anastomosis, Surgical↗

Visualization of diaphragmatic fenestration associated with catamenial pneumothorax.

Catamenial pneumothorax is a rare entity of unknown etiology characterized by recurrent accumulation of air in the thoracic space during or preceding menstruation. We documented the presence of a diaphragmatic fenestration during thoracoscopy, lending support for hypotheses involving diaphragmatic defects as possible avenues of air collection in the thorax.

Adult↗