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Carcinoma cuniculatum of the nail apparatus: report of three cases.

Three patients affected by carcinoma cuniculatum involving the nail apparatus are reported. The toes were affected in 2 cases, the thumb in 1 case. In the first patient the tumour developed in the subungual area and resulted in loss of the toe-nail. In the second patient the tumour originated on the dorsum of the toe and subsequently involved the proximal nail fold. In the third patient the tumour developed in the nail bed resulting in loss of the lateral part of the nail plate. The pathology showed in all cases invaginating strands of well-differentiated keratinocytes, some of which had central crypts containing keratinous debris. Radical excision of the tumour required disarticulation of the digit in 2 cases, whereas Mohs micrographic surgery was performed in the third case.

Aged↗

Laryngeal stenosis after supracricoid partial laryngectomy.

The purpose of this study was to review the incidence, risks, management, and outcomes of nontumoral laryngeal stenosis after supracricoid partial laryngectomy (SCPL) in a case series of 376 consecutive SCPLs performed at 1 institution from 1975 to 1995 with a minimum of 3 years of follow-up. Post-SCPL nontumoral symptomatic laryngeal stenosis was defined as an inability to decannulate patients before the 60th postoperative day (group 1) or the development of dyspnea (in patients without local recurrence) after an initial period of prolonged, successful decannulation (group 2). Of 376 SCPLs performed, nontumoral symptomatic laryngeal stenosis developed in 14 (3.7%). There were 7 patients (1.85%) in group 1 and 7 patients (1.85%) in group 2. In univariate analysis, none of the following variables appeared to be statistically related to the risk of immediate stenosis (group 1): age, gender, comorbidity, diabetes mellitus, symptomatic gastroesophageal reflux, arteritis, preoperative radiotherapy, arytenoid cartilage disarticulation, type of reconstruction performed, and postoperative radiotherapy. A delayed laryngeal stenosis (group 2) was statistically more likely to occur if the reconstruction performed at the time of SCPL was a cricohyoidopexy (p = .01). Successful management of the laryngeal stenosis without permanent tracheostomy was achieved in 5 group 1 patients and 3 group 2 patients. We believe that stenosis in group I patients arose through technical error, whereas group 2 patients seemed to suffer from problems of healing, mainly cicatricial narrowing of the airway at the site of the cricohyoidal impaction, or pexis. As a result, whereas laryngeal stenosis in group 1 patients was usually more easily correctable through dilation, laser incision, or resection of redundant tissue or revision of the impaction, laryngeal stenosis in group 2 patients presented a more difficult and frustrating complication. The management and outcomes of these patients are presented.

Adult↗

Evaluation of three cyanoacrylate glues for ossicular reconstruction.

We evaluated and compared the separate effects of ethyl, isobutyl, and fluoroalkyl cyanoacrylate on the promontory mucosa and surgically disarticulated incudostapedial joint in the adult cat middle ear. The animals were sacrificed at 10-, 30-, and 60-day intervals after glue application. All three cyanoacrylates elicited a chronic inflammatory response when placed directly on the promontory mucosa. The use of ethyl and isobutyl cyanoacrylate resulted in persisting discontinuity of the incudostapedial joint with erosion of the incus. Fluoroalkyl cyanoacrylate maintained incudostapedial continuity without ossicular erosion. Ethyl and isobutyl cyanoacrylate are probably not appropriate for middle ear surgery. The less toxic fluoroalkyl cyanoacrylate may be useful as an ossicular adhesive in selected cases. Our findings are further contrasted with those obtained in similar studies with methyl and butyl cyanoacrylate. The effects of each of the five cyanoacrylates are reviewed in the continuing search for a safe and effective ossicular adhesive.

Animals↗

The annular ligament attachment to the normal human stapes footplate. A scanning electron microscopic study.

Following disarticulation of the stapes from the oval window, the free edge of the adult human stapes was examined with the scanning electron microscope. Regions of the articulating surface of the rim were examined and found to vary considerably. Anterior, posterior, and lateral ligaments are described, each with tympanic, intermediate, and lateral components.

Adult↗

Auditory brain stem response monitoring during middle ear surgery.

Conductive hearing loss can be determined in the course of middle ear surgery by sound probe stimulation and simultaneous recording of auditory brain stem responses. Mechanical properties of the ossicular chain, usually judged subjectively by the surgeon's visual and tactile senses, can be quantified objectively. Thus, disarticulation of ossicles can be localized precisely, and fixation of the head of the malleus can be differentiated from stapes fixation. Moreover, the function of the reconstructed ossicular chain or prosthesis may be ascertained.

Audiometry, Evoked Response↗

Transmastoid decompression of the facial nerve in temporal bone fracture.

Among 41 cases of facial palsy caused by closed heart injury, temporal bone fractures were surgically confirmed in 36 cases, of which there were two mixed fractures and 34 longitudinal fractures. The fracture involved the geniculate ganglion area in 20 cases (55%). In 15 cases, decompression of the facial nerve was carried out using the transmastoid supralabyrinthine approach with disarticulation of the incus; in only five cases was the middle fossa approach used. The technique avoids the craniotomy for the middle fossa approach and is a reliable method of treatment in the majority of patients with facial palsy caused by temporal bone fracture involving the geniculate ganglion area.

Facial Nerve↗

Routing through the health care system and level of functioning of lower limb amputees.

OBJECTIVES: To describe the routing through the health care system and the level of functioning of a consecutive series of lower limb amputees at a general Dutch hospital. METHODS: A descriptive cohort study (medical records examination) with a follow-up interval of 11.7 months. All 124 major lower limb amputations (ankle to hip) between 1 July 1989 and 31 December 1992 are included in the study: 123 patients, average age 73.8 years, 96% vascular disease. Amputation levels are 55.3% transfemoral, 12.2% knee disarticulation and 32.5% transtibial. At follow-up two patients are missing. RESULTS: Before admission to hospital 75.6% of patients are able to walk and 79.9% live independently. Discharge destinations from hospital are 22.5% home, 42.3% inpatient rehabilitation and 32.4% nursing home. At follow-up, 59% of surviving patients have a prosthesis, 47.7% are able to walk and 70.5% live independently. Mortality after one year is 28.5%. Poor preoperative walkers seem to die more often within the first year and have less chance of being fitted with a prosthesis. Poor walkers, older than 75, with diabetes mellitus and a transfemoral amputation seem to stay more often in a nursing home after one year. DISCUSSION: Although the results are largely comparable with other studies, there appear to be differences in age, amputation level and course and duration of treatment. The predicting factors found here may help the rehabilitation specialist in advising on the best moment and level of amputation and course of treatment.

Activities of Daily Living↗

Treatment of recurrent sarcoma of the extremities by isolated limb perfusion using tumor necrosis factor alpha and melphalan.

BACKGROUND: 24-60% of patients with soft tissue sarcoma shows local recurrences after treatment of the primary tumor. The event is associated with a high incidence of macroscopic or microscopic metastases and a poor survival. Our goal is to preserve a patient's functional limb by treating such cases with isolated limb perfusion (ILP) with recombinant human tumor necrosis factor alpha (rHu TNF-alpha) and melphalan, which have demonstrated a potent antitumor activity in vivo and in vitro studies. METHODS: During the period November 1991 to November 1995, 10 patients with unresectable recurrent soft tissue sarcoma of the limb were treated by ILP at intermediate hyperthermia (40-40.5 degrees C) with rHu TNF-alpha and melphalan. Two patients also received recombinant interferon gamma (rIFN-gamma) before and during ILP. We used a range of 2-4 mg for rHu TNF-alpha and 50-100 mg of melphalan. rIFN-gamma was administered on days -2 and -1 (15 x 10(6) IU) subcutaneously and the same dose was injected in the arterial line during ILP. RESULTS: No perioperative surgical complication was observed. Local toxicity was moderate (grade I or II); general toxicity was observed in 6 patients (2 grade I and 4 grade III). Complete response was obtained in 7 cases; 2 patients had a partial response and finally 1 was a nonresponder and showed local progression, which required surgical amputation. Tumor necrosis (observed in 5 cases) was maximal in 4 patients (80-100%) and absent in the patient who had local progression. CONCLUSIONS: The results we obtained with the treatment of soft tissue sarcoma confirm the efficacy of ILP as a limb-sparing methodology for unresectable recurrences. Furthermore, rHu TNF-alpha and melphalan confirmed their antitumor activity when associated with hyperthermia. Amputation or disarticulation may be reliable as a second-choice treatment for these patients.

Adult↗

Codominance of the individual posterior cruciate ligament bundles. An analysis of bundle lengths and orientation.

BACKGROUND: It is unclear how each bundle of the posterior cruciate ligament contributes to posterior knee stability. HYPOTHESIS: Changes in bundle orientation and length occur such that neither bundle dominates in restraining posterior tibial motion throughout knee flexion and extension. STUDY DESIGN: Controlled laboratory study. METHODS: Six fresh-frozen cadaveric knees were studied in a joint-testing rig with individual quadriceps and hamstring muscle loading. Kinematic data for the tibia and femur were obtained at knee flexion angles from 0 degrees to 120 degrees. The joint was then disarticulated, and the insertions of the two bundles on the tibia and femur were digitized. RESULTS: Length of the anterolateral bundle increased with increasing knee flexion angle from 10 degrees to 120 degrees. Length of the posteromedial bundle decreased with increasing knee flexion angle from 0 degrees to 45 degrees and increased slightly from 60 degrees to 120 degrees. Length of the anteromedial bundle was significantly less than that of the posteromedial at 0 degrees, 10 degrees, and 20 degrees of knee flexion. The anterolateral bundle was significantly more horizontal at flexion angles of 0 degrees, 10 degrees, 20 degrees, 30 degrees, and 45 degrees (P < 0.05). The posteromedial bundle was more horizontal at 120 degrees. CONCLUSIONS: Changes in orientation take place such that neither bundle dominates in restraining posterior tibial motion throughout knee flexion and extension. CLINICAL RELEVANCE: Double-bundle reconstructions achieve more physiologic knee function.

Aged↗

Popliteal hiatus of the lateral meniscus. Anatomy and measurement at dissection of 10 specimens.

The popliteal hiatus is the opening defined by the fascicles of the lateral meniscus, which permits the popliteal tendon to pursue its course from the tibia to its femoral attachment. The medial border of the popliteal hiatus is the body of the meniscus. Ten fresh-frozen knee specimens from human adult males (with no evidence of previous surgery to the knees) were dissected. The joints were disarticulated so that only the lateral structures remained intact. The perimeter of the meniscal attachment anterior to the hiatus measured 4.2+/ - 0.3 cm, and the perimeter posterior to the hiatus measured 3.4 +/- 0.5 cm. The total perimeter of the lateral meniscus was 8.9 +/- 0.7 cm. The length of the superior fascicle of the lateral meniscus was 0.9 +/- 0.2 cm. In this series, the length of the hiatus was 1.3 +/- 0.1 cm. The anatomy of the popliteal hiatus was constant. The popliteal hiatus is an anatomical structure and must be differentiated from pathologic lesions common to the same area.

Adult↗

[Psychiatric chronicity and organization of services].

A study conducted in a Montreal area psychiatric institution focuses on the impact of chronic patients on in-patients services delivery system. This article shows a disarticulation of the system, from the first to the second line and within the second line. The authors suggest that when the length of stay is extended beyond a certain time frame, it becomes increasingly difficult to reconcile continuity and complementarity of services: by congesting the system, chronic psychiatric population is decreasing the accessibility of services.

Chronic Disease↗

Comparison of the syndesmotic staple to the transsyndesmotic screw: a biomechanical study.

BACKGROUND: Controversy still exists about treatment of syndesmotic injuries. This study compared the fixation strengths and biomechanical characteristics of two types of ankle fracture syndesmotic fixation devices: the barbed, round staple and the 4.5-mm cortical screw. METHODS: Cadaveric testing was done on 21 fresh-frozen knee disarticulation specimens in biaxial servohydraulic Instron testing equipment. Submaximal torsional loads were applied to specimens in intact and Weber C bimalleolar fracture states. The specimens were then fixed with one of two techniques and again subjected to submaximal torsion and torsion to failure. Biomechanical parameters measured included tibiofibular translation and rotation, maximal torque to failure, and degrees of rotation at failure. RESULTS: Compared to the intact state before testing, the staple held the fibula in a more anatomic position than the screw for mediolateral and anterior displacements (p < 0.01). With submaximal torsional testing, the staple restored 85% of the tibiofibular external rotation and all of the posterior translation values as compared to the intact state. The screw resulted in 203% more tibiofibular medial translation and 115% more external rotation than the intact state. The degree of tibial rotation during submaximal torsional loading was restored to within 15% of intact values but was 21% less with the screw. There was no statistical difference between the screw and staple when tested in load to failure. Tibiotalar rotation at failure was statistically different with the staple construct, allowing more rotation as compared to the screw. CONCLUSION: The staple restored a more physiologic position of the fibula compared to the syndesmotic screw. Both provided similar performance for the load to failure testing, while the screw reduced tibial rotation more after cyclic loading. There was more tibial rotation before failure for the staple, suggesting a more elastic construct. This study provides biomechanical data to support the clinical use of the syndesmotic staple.

Ankle Injuries↗

Preservation of residual foot length in partial foot amputation: a biomechanical analysis.

BACKGROUND: Partial foot amputation may be preferred to more proximal amputation because of the perceived improvement in function associated with preserving foot length and the ankle joint complex, thus enabling normal gait and push-off. Clinically, partial foot amputees display significant wasting of the triceps surae musculature, strongly indicative of disuse. This investigation aimed to examine the belief that preserving residual foot length should be the primary operative objective necessary to maintain normal foot and ankle function. METHOD: The gait patterns of eight partial foot amputees and a cohort of matched non-amputee control subjects were analyzed using a peak three-dimensional (3D) motion analysis system incorporating an AMTI force platform (Advanced Mechanical Technology Inc., Waterton, MA). Amputee subjects used their own prostheses for the evaluation. RESULTS: Amputations disarticulating the metatarsophalangeal (MTP) joint had little impact on the normal pattern of ankle power generation. However, amputation proximal to the MTP joint level resulted in virtually negligible power generation across the ankle, regardless of residual foot length. Subjects compensated for the lack of ankle power generation by adopting strategies in which the hip became the primary source of power to advance the body forward. CONCLUSIONS: The primary reason for a partial foot amputation is to preserve the normal function of the foot and ankle complex associated with push-off. As such, surgery should strive to preserve the metatarsal heads to allow amputees to use the ankle's contribution to walking. Given that amputation proximal to the metatarsal heads compromised the normal propulsive function of the foot and ankle, surgery should not strive to preserve residual foot length to maintain function but should instead aim to achieve good distal tissue coverage and healing, particularly given that the hip joint(s), not the ankle, become the primary source of power for walking.

Adult↗

Anatomy of ligamentous structures in the tarsal sinus and canal.

BACKGROUND: The descriptive morphology of the interosseous talocalcaneal ligament and other structures in the tarsal sinus and canal vary. An anatomical investigation of the ligamentous structures in the tarsal sinus and canal identified two distinct ligaments, the interosseous talocalcaneal ligament and the anterior capsular ligament, and three components of the medial root of the inferior extensor retinaculum. METHODS: Forty embalmed cadaver feet were examined. After disarticulation of the ankle joint, the posterior half of the talus was removed. The length, width, and thickness of the two ligaments and the three components of the extensor retinaculum in the tarsal canal and sinus were measured with calipers. Anatomical variations were recorded. RESULTS: The interosseous talocalcaneal ligament was band-like in 92.5% (38 of 40) of examined specimens, and the anterior capsular ligament was present in 95% (39 of 40) of specimens. The interosseous talocalcaneal ligament, the medial component of the inferior extensor retinaculum, and the talar component of the inferior extensor retinaculum had one or two distinct anatomical variations of morphology and attachments. The interosseous talocalcaneal ligament and the medial component of the extensor retinaculum formed a V shape in the tarsal sinus and canal. CONCLUSION AND CLINICAL RELEVANCE: We demonstrated the morphology and dimensions of the ligaments and components of the extensor retinaculum in the tarsal sinus and canal. Precise anatomy of the structures in the tarsal sinus and canal will strengthen our understanding of their function in the motion or stabilization of the subtalar joint. There may be a functional link between the medial component of the inferior extensor retinaculum and the interosseous talocalcaneal ligament.

Aged↗

Amputation of the great toe.

Four patients who had undergone reimplantation of the great toe to create a thumb were studied. The follow-up period ranged from 29 to 62 months. In all cases, the great toe was disarticulated at the metatarsophalangeal joint. The patients felt their feet functioned at approximately 85% of normal, and none had any significant complaint of metatarsalgia. The one patient who participated in sports after the surgery noted that it was difficult to "push off" moving away from the involved foot. X-ray examination demonstrated retraction of the sesamoids, which accounted for the increased plantar flexion of the first metatarsal shaft. The second metatarsophalanageal joint drifted into varus an average of 8 degrees. The Harris mat demonstrated that there was an increase in weightbearing beneath the second and third metatarsal heads. It appears as though, on the basis of this study, the loss of the great toe in this manner does not significantly affect the normal everyday function of an individual's foot.

Amputation, Surgical↗

The role of subtalar motion and ankle contact pressure changes from angular deformities of the tibia.

It is a well known entity that fractures of the tibia heal with some component of angular deformity. Ankle and subtalar joints may compensate for small degrees of angular deformities, but the exact amount of malunion that can be accepted without development of late sequalae has yet to be determined. Two recent studies from this institution have concluded that contact changes at the tibiotalar joint tend to be greater with distal third tibial fracture deformities compared to proximal and middle with the ankle in neutral, 5 degrees dorsiflexion, and 20 degrees of plantar flexion. Anterior and posterior bow deformities produced a greater change in contact area of the tibiotalar joint than with valgus or varus deformities. This phenomena may be possibly explained by the subtalar motion in the horizontal plane which averages 23 degrees. Thus, it was the primary purpose of this paper to determine the exact role, if any, in subtalar motion on tibiotalar contact in angular deformities of the tibia. To achieve this objective the subtalar joint was transfixed thereby eliminating its perceived compensatory movement. Six cadaveric lower extremities were disarticulated at the knee joint and stripped of soft tissue preserving capsular and ligamentous structures. A custom universal joint was used to create various angulatory deformities at proximal, middle, and distal third levels of the tibia.(ABSTRACT TRUNCATED AT 250 WORDS)

Ankle Joint↗

Triple arthrodesis through a single lateral approach: a cadaveric experiment.

Using a single lateral approach, triple arthrodesis was performed on six cadaveric feet. An attempt was made to obliterate the talocalcaneal, talonavicular, and calcaneocuboid joints. The limbs were subsequently disarticulated to allow for an inspection of the talonavicular, talocalcaneal, and calcaneocuboid joints. An estimate of cartilage and subchondral bone removed from each articular surface was made by a single observer (J.V.B.) by direct visual inspection. Results were as follows: calcaneocuboid joint, 90% of cartilage removed; talocalcaneal joint, 80% of cartilage removed; talonavicular joint, 38% of cartilage removed. Failures at the talonavicular joint were attributed to a poor appreciation of the anatomy of the talar head and poor observation. Complications involved in obliteration of the talonavicular joint from a single lateral approach included: inadvertent division of the talar neck; inadvertent division of the talar head; removal of excessive bone stock; medial skin punctures; and creation of an iatrogenic cut through the talar dome. Therefore, a triple arthrodesis through a single lateral approach, as described by Ryerson, Hoke, and Campbell, cannot be recommended. The talonavicular joint should be approached through an auxiliary medial incision, as recommended by Cracchiolo. This paper documents the experience of a beginner with this operation, and demonstrates the value of using the anatomy laboratory.

Arthrodesis↗

Tibiotalar joint dynamics: indications for the syndesmotic screw--a cadaver study.

Pronation-external rotation ankle injuries involve varying degrees of disruption of the syndesmotic ligaments. The loss of ligament support and alteration in the stability of the mortise have been postulated to lead to an increase in joint reactive forces and traumatic arthritis. The purpose of this study was to determine the changes in tibiotalar joint dynamics associated with syndesmotic diastasis as a result of the sequential sectioning of the syndesmotic ligaments to simulate a pronation-external rotation injury. Dissections were conducted on 10 fresh-frozen, knee-disarticulated cadaveric specimens which were then axially loaded in an unconstrained manner. Tibiotalar joint forces were measured at each level of sequential sectioning of the syndesmotic ligaments, the interosseous membrane, and finally the deltoid ligament. Complete disruption of the syndesmosis with the medical structures of the ankle intact resulted in an average syndesmotic widening of 0.24 mm and no significant change in the tibiotalar contact area or the peak pressure. However, deltoid ligament strain increases with sectioning of the syndesmosis. With the addition of deltoid ligament sectioning, there was an average syndesmotic diastasis of 0.73 mm, a 39% reduction in the tibiotalar contact area, and a 42% increase in the peak pressure. In a simulated unconstrained cadaveric model of a pronation-external rotation ankle injury that results in complete disruption of the syndesmosis, if rigid anatomic medial and lateral joint fixation is obtained and the deltoid ligament complex is intact, syndesmotic screw fixation is not required to maintain the integrity of the tibiotalar joint.

Ankle Injuries↗