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Pairings of ethanol sipper with food induces Pavlovian autoshaping of ethanol drinking in rats: evidence of long-term retention and effects of sipper duration.

AIMS: This study asks if repeated Pavlovian pairings of a sipper tube (conditioned stimulus, CS) with food (unconditioned stimulus, US) will induce Pavlovian autoshaping conditioned responses (CRs), consisting of drinking of either 6% ethanol or water from the sipper CS. This study also tests predictions derived from the autoshaping model by asking if sipper CS-directed drinking will be retained, despite the absence of training for several weeks, and, in addition, if drinking rate is a negative function of sipper CS duration. METHODS: Autoshaping procedures, conducted in two daily sessions, consisted of the brief insertion of the sipper tube CS followed by the response-independent presentation of food US. For the Ethanol group (n = 8), the sipper CS contained 6% ethanol, whereas for the Water group (n = 8), the sipper CS contained tap water. Saccharin fading procedures were employed, whereas for both groups, during days 1-19, the sipper CS contained 0.1% saccharin, and thereafter across training days the concentration of saccharin was gradually reduced (0.07, 0.035, 0.0%). Following elimination of saccharin, both groups were maintained in their home cages during a 27-day retention interval, and then re-evaluated for autoshaping of drinking of unsweetened ethanol and water. Thereafter, across days, the duration of access to the sipper CS (5.0, 7.5, 10.0, 15.0 s) during each autoshaping trial was increased. RESULTS: Both groups increased drinking across the first 19 days of training with sipper CS-food US pairings, and, at 0.0% saccharin, the Ethanol group consumed 14.76 ml of 6% ethanol per day, resulting in a daily ethanol consumption of 2.77 g/kg. For both groups, daily levels of drinking before and after the 27-day retention interval were comparable, attesting to the durability of the acquired drinking effects. At each CS duration, the Ethanol group consumed more millilitres of fluid per day than did the Water group, and for the Ethanol group, peak drinking of 24.0 ml of 6% ethanol per day was observed at the 10 s CS duration. For both groups, drinking rate (millilitres of fluid consumed per second of CS duration), was a declining monotonic function of CS duration, resulting in a daily ethanol consumption of approximately 4.2 g/kg for the Ethanol group. CONCLUSIONS: These data reveal that these sipper CS-food US autoshaping procedures induce drinking in rats that is durable and negatively related to increasing CS duration. The effects of both variables are consistent with the hypothesis that drinking from the sipper CS is a Pavlovian autoshaping CR. Autoshaping of drinking in the Water group is observed despite the absence of water deprivation, and even more fluid is consumed by the Ethanol group than by the Water group. The high volumes of ethanol consumed during brief daily sessions suggest that Pavlovian autoshaping procedures may provide an animal learning model of binge drinking.

Alcohol Drinking↗

PubMed1994

Fluoxetine attenuates alcohol intake and desire to drink.

Several serotonin uptake inhibitors, including the long-acting fluoxetine, have been found to decrease alcohol intake in moderately dependent alcoholics. While the mechanism of their effect is not fully elucidated, a previous study with citalopram indicated that decreased desire to drink may be an important factor. Therefore, we tested fluoxetine effects on alcohol intake and desire to drink in a placebo-controlled study. Subjects, recruited by advertisement, were mildly/moderately dependent alcoholics (12 male, four female, aged 19-59 years, healthy, non-depressed) who did not believe they had a drinking problem and were not requesting treatment. After a 1 week baseline they received, single-blind, 2 weeks placebo followed by 2 weeks fluoxetine 60 mg/day. As out-patients, subjects recorded daily standard drinks (13.6 g ethanol) and rated interest, desire, craving and liking for alcohol biweekly. Each out-patient period was immediately followed by a double-blind experimental drinking session. Out-patient daily drinks slightly decreased during fluoxetine to 6.6 +/- 0.9 (mean +/- S.E.M.) compared with during placebo (7.16 +/- 0.95, p = 0.07, N.S.) and baseline (7.18 +/- 1.0, p > 0.1, N.S.). Desire, interest and craving for alcohol decreased during fluoxetine vs placebo baseline (p < 0.05), but not vs placebo. Appetite loss and decrease in food intake (p < 0.01, fluoxetine vs placebo) correlated with each other (r = 0.91, p < 0.01) but neither correlated with decrease in alcohol intake (appetite: r = 0.26, N.S.; food intake: r = 0.22, N.S.). Weight loss occurred during fluoxetine (p < 0.05 vs placebo) but did not correlate with decrease in alcohol intake (r = 0.1, N.S.). In the experimental drinking sessions after placebo and fluoxetine treatments subjects rated their desire for each of 18 mini-drinks (each one-third of a standard drink) offered at 5 min intervals. Fluoxetine decreased desire to drink throughout the sessions; both mean and maximum desire ratings were lower after fluoxetine than after placebo (ANOVA, p < 0.05). Therefore, fluoxetine seems to have a robust effect on decreasing desire for alcohol. We propose that in the absence of intention by subjects to reduce drinking, their habitual drinking patterns mitigated against reduced consumption in the out-patient phase. However, fluoxetine could be a useful adjunct for patients in a treatment context who are motivated to reduce their drinking.

Adult↗

PubMed1992

A statistical approach to an alcoholic drinking history.

The drinking history of a middle-aged male was analyzed statistically on the basis of eight and a half years of notes on the number of drinks consumed per day. During the period his average number of drinks per drinking day increased from about 7 in 1974 to a peak of about 16 in 1980 while the number of abstinent days varied between 23% and 54% with no clear trend. These figures are of the same magnitude as published reports on drinking among alcoholics. Time-series models of intake or drinking frequency could not describe adequately the time-structure of annual or monthly consumption. Occurrence of drinking was analyzed as a random series of events. The time-structure of the series was highly irregular and deviated greatly from the Poisson hypothesis which assumes that each day has an equal probability of becoming a drinking day independently of previous days. Instead, drinking days were clustered into sprees with an average length of 7 days, high variance and a very skew distribution, separated by abstinence periods with an average length of 4 days and a similarly shaped distribution. The entire history could be partitioned into 286 alternating drinking and abstinence intervals, one day intervals included. The drinking rhythm was very stable: no significant trends in the lengths of either type of interval could be found. The main findings are the surprising stability of the drinking rhythm, its independence of the growing amounts consumed, and the independently varying abstinence interval lengths. Even in the absence of reporting and memory bias, such a pattern of drinking may produce very inaccurate recall of the actual long-term alcohol intake, if the recall period is short. The results suggest that periods shorter than one month should be avoided when asking questions about alcohol intake, for example, in research on the effects of treatment on alcoholism or alcohol intake on health.

Adaptation, Psychological↗

PubMed1993

Relative frequency of heavy drinking and the risk of alcohol dependence.

Data from a national representative sample of US adults were analyzed to determine the association between the relative frequency of heavy drinking (the proportion of drinking occasions on which 5+ drinks were consumed) and past-year alcohol dependence, adjusting for the influences of average ethanol intake and sociodemographic factors. Fifty-seven percent of current drinkers reported never drinking 5+ drinks, and 21% drank 5+ drinks at least once but on less than 10% of all drinking occasions. Nine percent reported drinking 5+ drinks on at least half of all drinking occasions. Average daily intake was positively correlated with the relative frequency of heavy drinking, and both consumption measures were positively associated with the risk of alcohol dependence. Increases in either relative frequency of heavy drinking or average ethanol intake reduced, but did not eliminate, the effect of the other on the risk of dependence. The excess risk of dependence associated with frequent heavy drinking varied among population subgroups and was increased by age, education, and female gender.

Adolescent↗

PubMed2004

Ten-year patterns of alcohol consumption and drinking problems among older women and men.

AIMS: This study focused on changes in 10-year patterns of alcohol consumption among older women and men, late-life and life history predictors of drinking problems, and gender differences in these predictors. DESIGN, SETTING, PARTICIPANTS: A sample of late-middle-aged community residents (N = 1291) who had consumed alcohol in the past year or shortly before was surveyed at baseline and 1 year, 4 years and 10 years later. MEASUREMENTS: At each contact point, participants completed an inventory that assessed their alcohol consumption, drinking problems and health-related and life context factors. Participants also provided information about their life history of drinking. RESULTS: Over the 10 years, the proportion of individuals who consumed alcohol declined. Among individuals who continued to drink, women and men showed comparable declines in alcohol consumption, minor concomitants of alcohol consumption and drinking problems. In addition to the amount of alcohol consumption, smoking, friends' approval of drinking and avoidance coping consistently predicted late-life drinking problems. With respect to life history factors, heavy drinking, drinking problems and increased drinking in response to life events were related to a higher likelihood of late-life drinking problems; obtaining help from family members and friends and, among men, participation in Alcoholics Anonymous, were related to a lower likelihood of problems. CONCLUSION: Older women and men show comparable declines in alcohol consumption and drinking problems. Specific late-life social context and coping variables, and life history indices, are risk factors for late-life drinking problems among both women and men.

Age Factors↗

PubMed1983

Renin dependence of captopril-induced drinking after ureteric ligation in the rat.

In experiments lasting 8 h, low (0.5 mg kg-1) or medium (5 mg kg-1) subcutaneous doses of the angiotensin-converting enzyme inhibitor captopril were mildly dipsogenic in sham-operated rats, much more so in rats subjected to bilateral ureteric ligation and not at all in bilaterally nephrectomized rats. Rats with ligated ureters drank enough water to gain weight during the experiments. All other groups lost weight. The enhanced responsiveness of rats with ligated ureters, despite fluid retention, shows that captopril-induced drinking was not secondary to increased renal fluid loss. Ureteric ligation alone which caused some increase in renin secretion was mildly dipsogenic compared with sham operation. Captopril caused further increases in plasma renin concentration and more drinking suggesting that the captopril response is renin-dependent. The failure of the nephrectomized rat to drink after captopril also shows that the response is renin-dependent. The highest dose (50 mg kg-1) of captopril did not at first stimulate drinking, though water intake increased later. Slowness to drink was not the result of general depression of behaviour since drinking in response to subcutaneous hypertonic NaCl or intracranial angiotensin II was not inhibited by the highest dose. Slowness to drink after the highest dose was attributable to blockade of converting enzyme centrally as well as peripherally. This meant that the increased circulating angiotensin I resulting from peripheral blockade of converting enzyme was only slowly converted to angiotensin II in the brain. When cerebral conversion of angiotensin I was prevented by a single intracranial injection of 25 micrograms captopril, drinking in response to the lower doses of captopril was also inhibited in normal rats and in rats with ligated ureters. The same intracranial dose of captopril also inhibited drinking in response to intracranial injections of renin or angiotensin I, but not angiotensin II. The time course of inhibition of renin-induced drinking was similar to that of inhibition of subcutaneous captopril-induced drinking. In conclusion, subcutaneous captopril causes increased water intake through activation of the renal renin-angiotensin system, an effect that is enhanced when the system has already been partly activated by ureteric ligation. Increased circulating angiotensin I resulting from blockade of peripheral converting enzyme must be converted to angiotensin II in the brain in order to stimulate drinking. Drinking is not the consequence of increased fluid loss.

Angiotensins↗

PubMed1994

A prospective study of the precursors to problem drinking in young adulthood.

This study was part of the Jyväskylä Longitudinal Study on Social Development. The subjects (196 males, 173 females) were studied at age 8, 14 and 26. Three components in drinking habits were obtained at age 26: social, problem and controlled drinking. Moderate to severe problem drinking was obtained for 26% of the men and 1% of the women, and mild problem drinking for 23% of the men and 15% of the women. Problem drinking (defined by the CAGE Questionnaire, arrest for alcohol abuse and other indicators of heavy drinking) was directly accounted for by poor school success at age 14 and, for men, by conduct problems and low anxiety. Variables at age 8 that contributed indirectly to adult problem drinking were aggression, low anxiety, low prosociality and poor school success for men, and high anxiety and poor school success for women. Women and men differed in the effect of social anxiety; in men, anxiety was a protective factor against problem drinking; in women, it was a risk factor. Although conduct problems often precede severe problem drinking, other risk factors may exist among sons of alcoholic parents. Parental drinking had a significant threshold effect on male off-springs' drinking: if parental drinking was low, there was less problem drinking among the male offspring than if a mild dependence on alcohol was observed in the parents.

Achievement↗

PubMed1995

Predicting adolescents' intentions to drink alcohol: outcome expectancies and self-efficacy.

OBJECTIVE: This article examines the relationship between intention to drink alcohol, alcohol outcome expectancies and alcohol-related self-efficacy among Norwegian adolescents. The relationship of expectancies, intention and self-efficacy was assessed for respondents of different ages and different drinking experience. METHOD: Data were collected from all seventh and ninth graders in 12 randomly selected schools in Norway. The self-administered questionnaire contained a short version of the Alcohol Expectancy Questionnaire for Adolescents and measures of intentions to drink in the next 12 months, current alcohol use and alcohol-related self-efficacy (e.g., ability to refuse alcohol). RESULTS: Results showed that both alcohol outcome expectancies and previous experience with alcohol were related to intentions to drink alcohol in the near future. Drinking experience had a larger impact than a 2-year age difference on the associations between alcohol outcome expectancies, alcohol-related self-efficacy and intention to drink. A significantly higher proportion of adolescents with drinking experience reported positive alcohol expectancies, poor alcohol-related self-efficacy and strong intention to drink alcohol than did those adolescents without drinking experience. CONCLUSIONS: Personal drinking experience was a stronger predictor of drinking intentions than was age. Still, both alcohol outcome expectancies and alcohol-related self-efficacy are significant predictors of intention to drink among both seventh and ninth graders, independent of previous drinking experience. This study indicates that postponing the onset of alcohol experimentation could be a major goal in primary alcohol prevention among adolescents, although longitudinal confirmation of these results is needed.

Adolescent↗

PubMed1998

Social settings and situations of underage drinking.

OBJECTIVE: Social settings and situations of underage drinking were described for students from 15 communities in Minnesota and Wisconsin. Reports of their last drinking event, including setting, number of persons drinking with them, number of those persons under age 21, and whom they were with, were examined. The role of these variables in the prediction of having five or more drinks on one occasion was assessed. METHOD: Ninth graders (n = 2,269) and 12th graders (n = 2,377) who reported using alcohol in the last 30 days were included in the sample from a nested cross-sectional survey design. Bivariate analyses were performed between the situational variables and gender, number of older siblings and drinking behavior. Chi-square statistics were divided by an estimate of the design effect and multivariate analyses used mixed-model regression to correct for the nesting of individuals within communities. RESULTS: Situations and settings of drinking differed according to age and drinking behavior. Twelfth graders were less likely to drink with parents or other adults than 9th graders and more likely to drink in someone else's home, and in large groups where nearly everyone was underage. Persons reporting having five or more drinks on one occasion in the last 2 weeks were more likely to report drinking with peers, in large groups of underage persons and away from home. CONCLUSIONS: Interventions to reduce use of alcohol by youth must focus on the context in which the drinking is taking place in addition to other factors. Policy or educational interventions that seek to alter the situations and settings of underage drinking may be effective in reducing consumption of alcohol in adolescents.

Adolescent↗

PubMed1998

Drinking over the life course within gender and ethnic groups: a hyperparametric analysis.

OBJECTIVE: This study examines drinking patterns over the life course among males and females and among three ethnic groups (whites, blacks and Hispanics) in order to compare gender group and ethnic group differences in alcohol use as a continuous function of age. METHOD: Data are from a general population sample of 13,553 respondents aged 12 to 80 interviewed by telephone in 20 urban areas of the United States. Drinking measures include total consumption, drinking participation, drinking frequency and average drinks per occasion. RESULTS: In the total sample over age cohorts, total consumption, participation and average drinks per occasion rose rapidly before age 21, peaked in young adulthood and declined gradually thereafter. Drinking frequency rose rapidly before age 21, but generally showed no decline thereafter. As expected, compared to women, men consumed more total alcohol, were more likely to participate in drinking, drank more often and drank more per occasion. Men did not differ from women in the age at which peak drinking occurred. Relationships of drinking to ethnicity were more complex. Although white total consumption exceeded that of blacks and Hispanics over the entire life course, the other drinking measures involved interactions in which white participation and frequency exceeded that of blacks and Hispanics in later adulthood, but black and Hispanic average drinks per occasion exceeded that of whites in later adulthood. CONCLUSIONS: Differences in drinking patterns over the life course among gender groups and ethnic groups are largely a result of differences in rates of change over age cohorts in alcohol use, both in rates of increase in youth and of decrease thereafter.

Adolescent↗

PubMed2001

Drinking to cope, emotional distress and alcohol use and abuse: a ten-year model.

OBJECTIVE: This study examines the ability of baseline drinking to cope to predict drinking behavior across an ensuing 10-year period. In addition, it examines whether a propensity to consume alcohol to cope with stressors strengthens the link between emotional distress and drinking behavior. METHOD: The study uses survey data from a baseline sample of 421 adults (54% women) assessed four times over a 10-year period (i.e., baseline and 1-, 4- and 10-year follow-ups). RESULTS: Baseline drinking to cope was associated with more alcohol consumption and drinking problems at all four observations across the 10-year interval. Baseline drinking to cope also predicted increases in both alcohol consumption and drinking problems in the following year. Moreover, change in drinking to cope was positively linked to changes in both alcohol consumption and drinking problems over the interval. Individuals who had a stronger propensity to drink to cope at baseline showed a stronger link between both anxiety and depressive symptoms and drinking outcomes. CONCLUSIONS: Findings demonstrate the power of alcohol-related coping strategies in predicting long-term drinking behavior and they illustrate one way in which such coping is linked to alcohol use and abuse. More broadly, they underscore the importance of considering individual differences in emotion-based theories of drinking behavior.

Adaptation, Psychological↗

PubMed2003

Perceived social norms and their relation to university student drinking.

OBJECTIVE: The aims of this study were to compare university students' perceptions of drinking norms with actual student drinking norms, to examine the relationship between norm misperception and individual drinking status and to investigate the relative importance of three reference groups as potential determinants of individual drinking levels: young people in New Zealand of the same age and gender, local university students of the same age and gender and the closest friends of individual respondents. METHOD: In 2002 a randomly selected representative sample of 1,564 New Zealand university students aged 16-29 years completed an Internet-based survey of their alcohol use (response rate: 82%). Respondents were asked to estimate the incidence of heavy episodic drinking and vomiting in the three reference groups and to rate their own drinking in comparison. Estimates within +/- 10% of actual norms were rated as accurate; estimates above or below actual norms by more than 10% were rated, respectively, as overestimates and underestimates. RESULTS: The vast majority of women (80%) and men (73%) overestimated the incidence of heavy drinking among student peers. The incidence of vomiting was also overestimated, but to a lesser extent. The extents of overestimation for both heavy drinking and vomiting were strongly related to the individual's heavy drinking frequency (p < .001). Only 9% of drinkers believed they drank more than other students. Correlations of perceived norms and self-reported drinking increased with the proximity of the social grouping to the individual and were higher for women than for men. CONCLUSIONS: This New Zealand university sample showed strong evidence of norm misperceptions, consistent with the results of several U.S. studies. Perceived norms are strongly related to individual drinking levels. It is unclear whether norm misperceptions are a cause or effect of heavy drinking. Research in which norm misperceptions are corrected may assist in understanding their importance in the etiology and treatment of heavy drinking.

Adolescent↗

PubMed2005

Negative consequences and cognitions about drinking and driving.

OBJECTIVE: Drinking and driving has been found to be a highly persistent behavior, even after experiencing negative consequences, such as arrest. This study tested the association between consequences of drinking and driving and cognitions related to drinking and driving (e.g., attitudes, normative beliefs). We tested whether exposure to negative consequences was associated with perceptions of risk associated with drinking and driving. METHOD: Participants were 938 college students. The sample was 57% female and primarily white (86%). Questionnaire measures were used to assess alcohol use, drinking and driving behaviors, drinking and driving cognitions, and lifetime drinking and driving consequences. RESULTS: Results indicated that participants who had experienced consequences of drinking and driving (either as a driver or rider) reported more current drinking and driving and greater alcohol consumption. Analyses indicated that most cognition measures differentiated those reporting lifetime consequences from the rest of the sample, with the consequence groups reporting more risky cognitions. However, experiencing a personal consequence of drinking and driving was associated with perceiving negative consequences of drinking and driving to be more likely. CONCLUSIONS: These results provide evidence that most cognitive risk factors for drinking and driving remain high even after experiencing a negative consequence. This may contribute to the persistence of drinking and driving in prior offenders. The finding that the perception of negative consequences may be influenced by experiencing consequences may have implications for intervention and treatment efforts.

Adult↗

PubMed2006

Normative misperceptions and temporal precedence of perceived norms and drinking.

OBJECTIVE: Previous research has shown that students overestimate the drinking of their peers, and that perceived norms are strongly associated with drinking behavior. Explanations for these findings have been based largely on cross-sectional data, precluding the ability to evaluate the stability of normative misperceptions or to disentangle the direction of influence between perceived norms and drinking. The present research was designed to evaluate (1) the stability of normative misperceptions and (2) temporal precedence of perceived norms and drinking. METHOD: Participants were college students (N = 164; 94 women) who completed assessments of perceived norms and reported behavior for drinking frequency and weekly quantity. Most participants (68%) completed the same measures again two months later. RESULTS: Results indicated large and stable overestimations of peer drinking for frequency and weekly quantity. Results also showed that for weekly quantity, perceived norms predicted later drinking, but drinking also predicted later perceived norms. Results for frequency revealed perceived norms predicted later drinking, but drinking did not predict later perceived norms. CONCLUSIONS: These findings underscore the importance of longitudinal designs in evaluating normative influences on drinking. The present findings suggest that normative misperceptions are stable, at least over a relatively short time period. Findings support a mutual influence model of the relationship between perceived norms and drinking quantity but are more strongly associated with conformity explanations for the relationship between perceived norms and drinking frequency. Results are discussed in terms of implications for prevention interventions.

Adolescent↗

PubMed2006

A mixture model of discontinuous development in heavy drinking from ages 18 to 30: the role of college enrollment.

OBJECTIVE: The purpose of this study was to illustrate the use of latent class analysis to examine change in behavior over time. Patterns of heavy drinking from ages 18 to 30 were explored in a national sample; the relationship between college enrollment and pathways of heavy drinking, particularly those leading to adult heavy drinking, was explored. METHOD: Latent class analysis for repeated measures is used to estimate common pathways through a stage-sequential process. Common patterns of development in a categorical variable (presence or absence of heavy drinking) are estimated and college enrollment is a grouping variable. Data were from the National Longitudinal Survey of Youth (N=1,265). RESULTS: Eight patterns of heavy drinking were identified: no heavy drinking (53.7%); young adulthood only (3.7%); young adulthood and adulthood (3.7%); college age only (2.6%); college age, young adulthood, and adulthood (8.7%); high school and college age (4.4%); high school, college age, and young adulthood (6.3%); and persistent heavy drinking (16.9%). CONCLUSIONS: We found no evidence that prevalence of heavy drinking for those enrolled in college exceeds the prevalence for those not enrolled at any of the four developmental periods studied. In fact, there is some evidence that being enrolled in college appears to be a protective factor for young adult and adult heavy drinking. College-enrolled individuals more often show a pattern characterized by heavy drinking during college ages only, with no heavy drinking prior to and after the college years, whereas nonenrolled individuals not drinking heavily during high school or college ages are at increased risk for adult heavy drinking.

Adolescent↗

PubMed2006

Eating and drinking activity of newly weaned piglets: effects of individual characteristics, social mixing, and addition of extra zinc to the feed.

In production systems, piglets usually fast for a period after weaning, thereby increasing the risk of diarrhea and a reduction in growth. The low level of eating may relate to insufficient drinking activity, as solid feed intake must be accompanied by water intake. Mixing of newly weaned piglets is a well-known stressor and a common procedure in pig production. The effect of mixing on the temporal development of eating and drinking activity in newly weaned piglets has not been elucidated. High concentrations of zinc (Zn) in the feed improve the health and performance of piglets after weaning, but the underlying mechanisms are still obscure. One possibility is that Zn affects eating and drinking behavior. The effects of mixing 4 littermates from each of 2 litters and adding zinc oxide (ZnO; 2,500 ppm of Zn) to the feed were studied in a 2 x 2 factorial experiment using 123 piglets weaned at 27 d of age. Individual eating and drinking times during the initial 48 h after weaning were analyzed on 2 levels of aggregation, day and hour. The piglets spent less time eating on the first day after weaning compared with the second day (20 +/- 5 vs. 98 +/- 10 min, respectively; P < 0.001), whereas they spent more time drinking on the first day compared with the second day (13 +/- 1 vs. 9 +/- 0.5 min, respectively; P < 0.001). Eating and drinking times were positively associated (P < 0.001). Females ate for longer than males (61 +/- 8 vs. 44 +/- 7 min/24 h, respectively, P = 0.002), whereas sex did not affect drinking time. Drinking time increased (P = 0.003) and eating time decreased (P = 0.001) with increasing preweaning growth rate and weaning weight. Neither mixing nor addition of ZnO affected the daily eating time. However, nonmixed piglets given 2,500 ppm of Zn as ZnO in the feed spent more time drinking per day (12 +/- 1 min) than did nonmixed piglets offered 100 ppm of Zn as ZnO (10 +/- 1 min; P = 0.002). Mixing also affected the hourly distribution of the drinking activity (P < 0.05). In conclusion, the drinking behavior of newly weaned piglets was more affected by the external factors, mixing and addition of ZnO to the feed, than the eating behavior. As eating and drinking are strongly associated, more focus should be paid to the water intake and the interplay between eating and drinking behavior in future studies aiming to reduce weaning problems.

Animal Feed↗

PubMed2002

Gender differences in collegiate risk factors for heavy episodic drinking.

OBJECTIVE: The present research examines gender differences in the way risk factors for heavy episodic drinking operate among undergraduate students. METHOD: A web-based survey was administered to students attending a large, midwestern research university in the spring of 1999. The sample consisted of 2,041 undergraduate students with a mean age of 21.1 years; 51% were female; 72% were white, 12% Asian, 5% African American, 4% Hispanic and 7% of other races. Heavy episodic drinking was defined as having five or more drinks in a row for men and four or more for women in the last 2 weeks. Two multiple risk factor approaches, continuous and categorical, were used to examine gender differences, with the latter focusing on three drinking patterns (nonheavy episodic drinking, heavy episodic drinking, and frequent heavy episodic drinking). RESULTS: The data indicated gender differences and similarities among risk factors for heavy episodic drinking within four major domains of risk factors (background, motivational, social context and behavioral). There were significant differences in the way class year and living arrangements operated as risk factors between undergraduate men and women. Gender similarities existed for precollege drinking, drinking motivations and several behavioral measures. The categorical analysis revealed several risk factors unique to the most harmful drinking pattern. CONCLUSIONS: This study lends support for gender differences between individual risk factors for heavy episodic drinking among undergraduate students. These differences have important implications for planning research and interventions aimed at reducing collegiate heavy episodic drinking.

Adult↗

PubMed2002

[Impact of a 10-year nation-wide campaign on knowledge of sensible drinking limits in Denmark].

INTRODUCTION: In Great Britain and in Denmark, strong efforts have been made to influence knowledge on the upper threshold of hazardous drinking. In Denmark, a campaign has been repeated every week 40 from 1990 to 2001 with information on the sensible drinking limits of 21 drinks per week for men and 14 drinks per week for women. The aim of this study was to examine the effect of this ongoing campaign on the level of knowledge of sensible drinking limits for men and women. MATERIAL AND METHODS: Every year from 1994 to 1999, random representative samples of 1,030 adult Danes were interviewed on the telephone. RESULTS: Our main finding was that the level of knowledge of sensible drinking limits for own sex increased in all subsets of the population throughout the period. However, at the end of the study period (1999), a total of 80% of highly educated young (18-25 years of age) men knew sensible drinking limits for own sex, while only 35% of uneducated older (more than 65 years old) men had knowledge on sensible drinking limits. The proportions were similar among women: Subjects admitting an intake higher than sensible for own sex, i.e. 21 and 14 drinks per week, respectively, had the highest knowledge of these drinking limits. DISCUSSION: We conclude that public health campaigns, such as the sensible drinking limit campaign, certainly has an impact on the level of awareness in the general population. Furthermore, those drinking more than 21 and 14 drinks per week, respectively, are reached by these campaigns.

Adult↗