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Socket preservation followed by dental implant supported restorative treatment: a case report.

Implant-supported restorative treatment continues to revolutionize all aspects of dentistry. Any clinical procedure(s) with the potential to enhance and improve the success of implant-supported restorative treatment will gain favor with both practitioner and patient. Socket preservation following tooth extraction appears to offer several clinical advantages in preparing the ridge for future implant placement. A case report is presented describing treatment of a patient with evidence of root resorption of the maxillary central incisors, resulting in extraction and socket preservation followed by implant supported restorative treatment.

Adult↗

Radiographic assessment of impacted mandibular third molar sockets filled with composite xenogenic bone graft.

OBJECTIVES: The main purpose of this study was to evaluate the radiographic aspect of the healing of extraction sockets filled with a xenogenic graft material (Gent-tech). METHODS: Thirty-nine patients ranging in age from 15 years to 25 years with bilateral impacted mandibular molars were chosen based on bilateral mandibular similarities. After tooth extraction, the socket was filled with the graft. The opposite site was left to heal naturally and served as a control. The experimental and control sites were chosen randomly. Bone density and crest healing were evaluated on digital radiographs taken immediately, 2 months and 6 months after surgery. The respective pixels values obtained with the Digora software were compared statistically. RESULTS: The results showed a significant decrease in the distance from the cemento-enamel junction to the alveolar bone crest, but no difference was found between the control and experimental groups. Bone density increased significantly, and there was difference between experimental and control groups. CONCLUSION: The analysed parameters observed by the authors were similar to those of the control group, suggesting xenogenic graft being an acceptable material and a graft option.

Absorbable Implants↗

Application of propolis to dental sockets and skin wounds.

The purpose of this study was to examine histologically the effects of propolis topical application to dental sockets and skin wounds. After topical application of either a 10% hydro-alcoholic solution of propolis or 10% hydro-alcoholic solution alone, cutaneous wound healing and the socket wound after tooth extraction were examined. The rats were sacrificed at 3, 6, 9, 15 and 21 days after the operation. The specimens were subjected to routine laboratory studies after staining with hematoxylin and eosin. It was concluded that topical application of propolis hydro-alcoholic solution accelerated epithelial repair after tooth extraction but had no effect on socket wound healing.

Animals↗

Intrusion injuries of primary incisors. Part I: Review and management.

Intrusion injuries commonly occur in the primary dentition. They can be described as luxation injuries resulting from an axially directed impact, which drives the tooth deeper into the alveolar socket. The impact results in compression of and damage to the periodontal ligament as well as injury to the pulp of the intruded incisor. In addition to rendering treatment to the intruded primary tooth, the dentist must also be aware of the possibility of an injury to the developing permanent teeth germs located in close proximity to the roots of the injured primary teeth. This review will discuss the characteristics, implications, and management of intrusion injuries of primary incisors.

Child↗

Effects of nicotine on the healing of extraction sockets in rats. A histological study.

The aim of the present study was to evaluate, histologically, the influence of nicotine on the socket healing after tooth extraction in rats. Eighty animals were divided into 4 groups of 20 rats each (2 control and 2 test groups). In the first and second test groups, the animals received one dose of nicotine hemisulfate solution once or twice daily, respectively. In the control groups, the animals received sterile saline once or twice daily. All solutions were injected subcutaneously on the dorsum of the animals for 4 weeks. The results showed that nicotine delayed alveolar healing, especially in terms of organization of connective tissue and osteoneogenesis. Angiogenesis was considerably impaired in the ossification area and in the gingival tissues as well. We concluded that the impairment of the healing of extraction sockets was found to be directly related to the drug dosage.

Animals↗

Exarticulation and reimplantation utilizing guided tissue regeneration: a case report.

The extraction and reimplantation of teeth is a technique that has been practiced for many years, resulting in successful retention of teeth for up to 30 years. Although evidence confirming the advantages of this technique is limited, clinical observations and histologic examinations have revealed some important factors that are prerequisites for success: limitation of the time the tooth is exposed to the extraoral environment and preservation of vital periodontal tissue attachments on root surfaces. The latter goal can be achieved by gentle, atraumatic removal of the tooth from its socket, and hence the term exarticulation and reimplantation is more representative of the technique. In the present case report, a maxillary lateral incisor with a developmental defect was treated by exarticulation and reimplantation and application of calcium sulfate. Exarticulation and reimplantation seems to be a useful clinical procedure, but controlled studies are required to confirm its efficacy.

Adult↗

The jumping distance revisited: An experimental study in the dog.

Following tooth extraction, a socket often presents dimensions that may be considerably greater that the diameter of a conventional implant. The present experiment was performed to study the healing that occurred adjacent to implants placed in recipient sites with a wide marginal defect. Four Labrador dogs were used. In the right side of the mandible, four experimental sites were prepared to receive titanium implants [sandblasted, large-grit, acid-etched (SLA) surface]. Traditional implant installation (control) was performed in one site. In the remaining three sites (test), a step drill was used to widen the marginal 5 mm of the canal. Following placement of an implant in a test site, a circumferential gap about 1-1.25 mm wide and 5 mm deep was present lateral to the implant. A resorbable barrier membrane was used to cover the implant and the bone tissue of two sites, while one site was left uncovered. Four months following implant installation, block biopsies of each implant site were obtained and prepared for ground sectioning. After 4 months of healing, the large marginal defect had been filled with newly formed bone. The degree of bone-to-implant contact between the newly formed tissue and the SLA surface was at all test sites high and similar to that obtained at control sites. The placement of a barrier membrane following implant installation did not improve the outcome of healing. We conclude that a marginal defect wider than 1 mm may heal with new bone and a high degree of osseointegration to an implant designed with a SLA surface.

Absorbable Implants↗

Resumed tooth development following avulsion of a permanent central incisor.

A case is presented in which an upper right central incisor was avulsed because of trauma at age six. At the time of trauma it was suspected that the pulp had remained in the socket although the tooth had been lost. No attempt was made to treat the socket, remove the pulp, or replant the tooth. Follow-up radiography showed that, despite initial apparent complete loss of the calcified portion of the tooth, root development proceeded to completion.

Child↗

A 3-year prospective multicenter follow-up report on the immediate and delayed-immediate placement of implants.

A total of 264 implants was placed in 143 patients using different immediate or delayed-immediate implant placement techniques in 12 different centers participating in a prospective multicenter study. The reason for tooth extraction was evaluated; bone quality and quantity were classified; socket depths were registered; and data on implant type, size, and position were collected. One hundred thirty-nine suprastructures were placed on 228 implants in 126 patients. A follow-up evaluation was done on 125 patients after 1 year of loading and on 107 patients after 3 years of loading. Clinical parameters (bleeding or not bleeding, pocket depth, and implant mobility) were evaluated after 1 and 3 years, and the marginal bone level after 1 year of loading was measured on radiographs. Clinical comparisons were performed to evaluate implant loss in relation to implant type, size, position, bone quality and quantity, socket depth, reason for tooth extraction, and placement method. In addition, life table analysis was done for cumulative implant survival rates. There was no clinical difference with respect to socket depth or when comparing the different placement methods. A higher failure rate was found for short implants in the posterior region of the maxilla and when periodontitis was cited as a reason for tooth extraction. Mean marginal bone resorption from the time of loading to the 1-year follow-up was 0.8 mm in the maxilla and 0.5 mm in the mandible. Over a period of 3 years, the implant survival rate was 92.4% in the maxilla and 94.7% in the mandible.

Bone Density↗

Rationale for socket preservation after extraction of a single-rooted tooth when planning for future implant placement.

After tooth extraction, the alveolar ridge will commonly decrease in volume and change morphologically. These changes are usually clinically significant and can make placement of a conventional bridge or an implant-supported crown difficult. If bone resorption is significant enough, then placement of an implant may become extremely challenging. Postextraction maintenance of the alveolar ridge minimizes residual ridge resorption and, thus, allows placement of an implant that satisfies esthetic and functional criteria. Recent advances in bone grafting materials and techniques allow the dentist to place implants in sites that were considered compromised in the past. This article focuses on the healing pattern of sockets, with and without the use of regenerative materials, and the rationale for preserving the dimensions of the extraction socket. Histologic and clinical evidence is reviewed to provide an in-depth understanding of the logic behind and value of socket preservation.

Alveolar Bone Loss↗

[Preimplant preparation of the extraction alveolus with the deproteinized bovine bone and calcium-sulphate].

BACKGROUND: Different materials are used to prevent the resorption of alveolar bone. The aim of this report was to show the radiographical and histological results prior to implant insertion, when a deproteinized bovine bone mineral (BioOss) and calcium-sulphate were placed into the extraction socket immediatelly after the tooth removal. CASE REPORT: A 22-year-old woman was scheduled for the removal of the second lower molar when the extraction socket was filled with BioOss covered with calcium-sulphate as a resorbable membrane. Primary closure of the surgical site was performed. Radiography was done 4 and 12 months later. One year after the surgery, when the implant was inserted, a biopsy of the new regenerated bone was obtained for the histological evaluation. The lamellar bone was evident using both materials. The resorption of BioOss was slow and the connective tissue was observed. CONCLUSION: Both materials had biocompatible and oseoconductive properties. One year after the grafting procedure, we observed the lamellar bone and partial resorption of BioOss, while calcium-sulphate showed no significant effect as a resorbable membrane.

Alveolar Process↗

Tissue reaction to orthodontic tooth movement in acute and chronic corticosteroid treatment.

OBJECTIVES: To study tissue reaction to orthodontic loading during the course of short- and long-term corticosteroid administration. DESIGN: 'Split-mouth' design to perform orthodontic tooth movement in 64 six-month-old male rats divided into groups: no drug administration (n = 19), acute (n = 22) and chronic (n = 23) 8 mg/kg/day corticosteroid treatment. Performed in the Department of Orthodontics at Aarhus University. EXPERIMENTAL VARIABLE: The upper left first molar was moved for 21 days. Bone markers were administered at 7 and 2 days before sacrifice. Histological sections were cut at the coronal level. OUTCOME MEASURE: Tooth movement rate, alveolar socket area, the relative extension of alveolar wall with erosion, and the mineralizing surfaces were measured and compared in the three groups. RESULTS: Tooth movement rate increased in the chronic group. The mechanical load induced an enlargement of the alveolar wall that was less pronounced in both medicated groups. In the acute group the drug suppressed bone resorption and formation without mechanical stimulus. Force application resulted in significant increase in the relative extension of resorption and formation in both drug groups; it was particularly pronounced in the chronic group. CONCLUSION: Because acute corticosteroid ingestion reduces bone turnover, in these patients orthodontic treatment might best be postponed until a time the patient is free of the drug. Chronic steroid ingestion leads to an increased biological reaction to mechanical perturbation indicating that the orthodontic force level should be reduced and controlled more frequently in patients on chronic steroid treatment.

Alveolar Bone Loss↗

Preservation and regeneration of alveolar bone by tissue-engineered implants.

Bone maintenance after dental extraction has a significant impact on the success of future treatment. The purpose of this study was to regenerate bone by implanting an engineered porous scaffold seeded with bone marrow mesenchymal stem cells (BMSCs) in a socket created by extraction of the lower left central incisor in rabbits, utilizing the principles of tissue engineering. It involved preparation and characterization of three-dimensional porous hollow root form scaffolds consisting of a poly-L-lactic acid:polyglycolic acid composite (PLG, 50:50), using a solvent casting/compression molding/particulate leaching technique. Porosity of the scaffolds was 83.71% with good interconnectivity and uniform distribution of the various pore sizes. The degraded scaffolds maintained their porosity and form for the first 2 weeks and their mass loss continued up to 6 weeks. The scaffolds developed viscoelastic behavior under dynamic compression; yet they lost their mechanical characteristics as they degraded. The scaffolds were seeded with BMSCs and examined by scanning electron microscopy. Cell proliferation and scaffold degradation were shown up to 2 weeks in vitro. The cultivated scaffolds were implanted in empty extraction sockets immediately after tooth removal. Four weeks later, bone regeneration was evaluated histologically in the healed sockets in three experimental groups: sockets left empty, sockets that received PLG without cells, and sockets that received PLG with cells. Radiographic evaluation, performed 4 weeks later for the three experimental groups, demonstrated preservation of alveolar bone walls in the extraction sockets that received PLG with cells as compared with the other two groups. The bone density profile for the healed sockets confirmed both histological and radiographic findings. The results of this study show promise in the area of dentoalveolar surgery, yet longitudinal studies under variable clinical situations would encourage the current application.

Animals↗

[Autografts and tooth transplants. Operative indications].

In order to evaluate the prognosis in tooth transplant procedure the literature on this subject was reviewed. The survival of the periodontal ligament is necessary to prevent ankylosis and root resorption. In order to obtain optimal clinical results, the following guidelines are proposed: preparation of the recipient site 2 weeks prior to graft placement, preservation of intact Pdl at time of extraction, rapid reimplantation of tooth in new socket, short term contention (2-3 weeks); endodontic therapy 8-10 weeks after tooth transplantation.

Adolescent↗

The prevention of 'dry socket' with topical metronidazole in general dental practice.

OBJECTIVE: The purpose of the study was to determine if the intra-alveolar application of topical metronidazole gel could reduce the incidence of alveolar osteitis (dry socket) following routine tooth extraction in molar and premolar extraction sites. DESIGN: This was a multicentre, double blind, randomised, placebo-controlled clinical trial. A total of 302 patients took part, of which 23 returned with alveolar osteitis. Of these, eight had received the metronidazole gel and 15 the placebo. SETTING: The study was carried out in three general dental practices by general dental practitioners working in England over the period 2000-2003. MAIN OUTCOME MEASURES: Following extraction of either a molar or premolar tooth, either a 25% metronidazole gel or KY Jelly was syringed gently into the socket. A painful post operative complication was recorded if either a dry socket was present or the patient returned with pain. RESULTS AND CONCLUSIONS: The difference in the incidence of alveolar osteitis between the placebo and the active gel groups was not significant and it was concluded that 25% topical metronidazole gel was not effective in reducing the incidence of alveolar osteitis. It was found that the incidence of alveolar osteitis reduced with increasing age and was more likely to occur in a patient with a previous history of the condition.

Administration, Topical↗

Histologic study of use of microfibrillar collagen hemostat in rat dental sockets.

The aim of this paper was to evaluate if the placement of microfibrillar collagen hemostat (MCH) into a dental socket interfered with healing. General anesthesia was administered to 30 adult male Albinus Wistar rats and the maxillary right central incisor was extracted. In the control group after each tooth was extracted, the socket was sutured. In the MCH group after each tooth was extracted, MCH was placed into the socket before suturing. Postoperatively, 5 animals were sacrificed from each group at 7, 21 and 28 days. The right maxilla was removed from each animal and histologic slides were stained with Masson's trichromic and hematoxylin and eosin. Quantitative and qualitative analyses were done. The percentage of bone area in the dental socket was quantified using the Image Lab 98 image analysis system. The bone area formation for the control and MCH groups was: 8.1% and 3.3% at 7 days, 34.4% and 33% at 21 days and 41% and 41.3% at 28 days, respectively. We concluded that MCH interferes with the beginning of dental socket healing but does not interfere with the final healing of the dental socket.

Alveolar Process↗