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[Development of a surgical simulator for interventions of the paranasal sinuses. Technical principles and initial prototype].

BACKGROUND: Traditional training methods for surgeons include anatomical studies on human cadavers. Limited availability and ethical problems led to the consideration of alternatives. The surgeon's level of training could be significantly increased by a interactive training system trough computer graphics and virtual reality (VR). METHODS: Two main issues addressed are the 3-D reconstruction process and 3-D interaction to guide the surgical instruments. To provide the virtual environment, a realistic representation of the region of interest with all relevant anatomical parts is required. This model has to be suitable for computer simulation, while preserving as accurately as possible important anatomic features. Therefore the concept of creating a 3-D representation semi-automatically was developed. Textures derived from endoscopic images are superimposed on the virtual anatomic structures and provide better realism. RESULTS: Intuitive handling of the surgical instruments is ensured by using the tracking technique. The system allows navigation via a virtual camera and interaction with the virtual anatomical structures. Currently the use of a force feedback system and the simulation of deformations of tissues is critical. CONCLUSIONS: The VR based simulation system offers an alternative to conventional training methods. The future role of surgical simulation depends on overcoming the current drawbacks to provide greater interactive realism: the integration of a force feedback system to simulate the resistance of anatomical structures and the simulation of tissue deformations--both currently under development.

Artificial Intelligence↗

J.-F.-B. Charrière: the man behind the "French" gauge.

Joseph-Frédéric-Benoît Charrière, a 19th century Parisian maker of surgical instruments, has by virtue of his ingenuity and advanced thinking, continued to have his presence felt in medicine throughout the 20th century. His most significant accomplishment was the development of a uniform, standard gauge specifically designed for use in medical equipment such as catheters and probes. Unlike the gauge system adopted by the British for measurement of needles and intravenous catheters, Charrière's system has uniform increments between gauge sizes (1/3 of a millimeter), is easily calculated in terms of its metric equivalent, and has no arbitrary upper end point. Today, in the United States, this system is commonly referred to as French (Fr) sizing. In addition to the development of the French gauge, Charrière made significant advances in ether administration, urologic, and other surgical instruments, and the development of the modern syringe.

France↗

The use of diathermy scissors in parotid gland surgery.

OBJECTIVE: To evaluate the benefits, as well as the possible complications, of the use of diathermy scissors in parotid gland surgery. DESIGN: Prospective study of the surgical procedures of the diathermy scissors and a retrospective comparison with a conventionally treated control group concerning cut-closure time. SETTING: Tertiary care referral academic center. PATIENTS: Prospective examination of 30 unselected patients undergoing superficial (n=23) or subtotal/total (n=10) parotidectomies performed with diathermy scissors. Indications were benign tumors (n=18), malignant tumors (n=12), and cystic lesions (n=3). In a control group (n=50), 36 superficial and 21 subtotal/total parotidectomies were performed. RESULTS: The use of diathermy scissors reduces the need to frequently change dissecting and coagulating surgical instruments. The scissors reduce intraoperative bleeding and therefore improve visualization and orientation in the surgical field. Postoperative bleeding or seroma and Frey syndrome were not observed. In 1 case, a salivary fistula was present for 3 weeks. Three cases of transient facial weakness occurred, all of which completely resolved by 6 months after surgery. In the control group, the cut-closure time ranged from 50 to 120 minutes (average, 87.6 minutes) during superficial parotidectomy; it ranged from 80 to 160 minutes (average, 130.0 minutes) during subtotal and total parotidectomy. In comparison, in the study group, the average time gain was 16 minutes during superficial parotidectomy when diathermy scissors were used, a statistically significant difference (P=.03). During subtotal and total parotidectomy with diathermy scissors, the average time gain was 19.3 minutes and was statistically not significant (P=.23). CONCLUSIONS: The results of the present study show that diathermy scissors are very well suited for most of the surgical steps in parotid gland surgery. They provide an elegant, safe, and fast surgical procedure, especially in the hands of an experienced surgeon.

Cysts↗

Noninvasive tracking of patient's head movements during computer-assisted intranasal microscopic surgery.

A noninvasive system designed for patient tracking during image-guided intranasal sinus surgery is described. It is based on optical digitizing with a custom-made registration and reference system, locatable surgical instruments, and a self-localizing operating microscope. Experimental and clinical results reveal a high degree of accuracy for the system. A mean spatial error of 0.82 +/- 0.31 mm was determined for repositioning of the reference system in a plastic model of the skull. For the positioning of the microscope, a mean error of 2.3 +/- 0.83 mm was calculated. Measurements of repositioning accuracy in 24 patients who received surgery for various sinus diseases had a mean spatial error of 1.56 +/- 0.76 mm. The 95% error interval for locating intranasal structures using the surgical instrument was 2.05 mm, and it was 4.92 mm using the microscope. These results suggest that the use of our noninvasive registration and reference system may be effective, accurate, and useful for noninvasive tracking of patient movements in computer-assisted intranasal surgery.

Head Movements↗

Endoscopic endonasal transsphenoidal surgery: procedure, endoscopic equipment and instrumentation.

INTRODUCTION: In the last 10 years the endoscopic endonasal transsphenoidal approach has been proposed as a minimally invasive procedure for the treatment of pathologies of the sellar region. This procedure introduces various advantages compared with the transsphenoidal microsurgical approach such as a wider vision of the surgical field, less traumatism of the nasal structures, greater facility in the treatment of possible recurrences, and reduced complications. Nevertheless, as for any new procedure, there is an initial learning curve that is somewhat steep, due to the necessity of acquiring the specific endoscopic skills. It is equally essential to be supplied with dedicated endoscopic equipment and appropriate surgical instrumentation, in order to optimize the different stages of the operation. DISCUSSION: Therefore, after our extensive experience with over 250 patients treated by means of the endoscopic endonasal transsphenoidal approach for pathologies of the sellar region, we describe herein the characteristics of the proper endoscopic instrumentation, as well as a set of surgical instruments intentionally conceived to respond to the specific characteristics of this new procedure.

Endoscopy↗

Laser medical instrumentation.

In spite of inadequate budgets, significant research and development studies have been made on laser medical instrumentation applications for both diagnosis and treatment. Diagnostic instrumentation includes the laser microprobe for cation microanalyses, cytofluorometry, interferometry, transillumination, holography and acoustical holography, and communications and information handling. Laser investigative surgical instrumentation includes lasers of argon, carbon dioxide, neodymium-YAG, and ruby, which are used as optical scalpels. Advantages of laser surgical instrumentation include precision, color absorption for lasers in the visible light range, and hemostasis.

Communication↗

[Surgery using master-slave manipulators and telementoring].

Master-slave manipulators enhance surgeons' dexterity and improve the precision of surgical techniques by filtering out surgeons' tremors and scaling the movements of surgical instruments. Among clinically available master-slave manipulators, the epoch-making system called "da Vinci" developed by Intuitive Surgical Inc. (Mountain View, CA, USA), equipped with 2 articulated joints at the tip of the surgical instruments allowing 7 degrees of freedom, mimics the movements of surgeons' wrists and fingers in the abdominal or thoracic cavity. Today advanced telecommunications technology provides us excellent motion images using only 3-ISDN telephone lines. Experienced surgeons at primary surgical sites have been able to perform complex procedures successfully by consulting specialists at remote sites. Because telecommunications costs have become lower each year, telementoring will be come a routine surgical practice in the near future. The usefulness of surgical telementoring has been greatly enhanced by the development of a technique to illustrate on video images from two directions. Moreover, remote advisory surgeons will be able to provide the optimal operative field to operating surgeons using robotic camera holders with voice-recognition systems. In the near future, when master-slave manipulators will also be coupled with telementoring systems, remote experts could actually perform complex surgical procedures.

Humans↗

A report of an outbreak of postoperative endophthalmitis.

We report an outbreak of endophthalmitis following cataract extraction or secondary intraocular lens (IOL) implantation in a 400-bed general hospital in northern Thailand. From December 1997 to September 1998, of 329 patients who had undergone cataract extraction or secondary IOL implantation in the hospital, 31 (9.4%) developed postoperative endophthalmitis. The interval between the operation and the clinical diagnosis of endophthalmitis ranged from 5 to 74 days with a median of 15 days. Of the 31 cases of endophthalmitis, 18 occurred in phacoemulsification (PE) with IOL, 11 in extracapsular cataract extraction (ECCE) with IOL, and 2 in secondary IOL implantation. Patients who had undergone PE with IOL had a significantly higher rate (12.4%) than those of ECCE with IOL (6.3%). The infection rates also increased with the order of the operations within each operation period (morning or afternoon); later operations were at higher risk. Our findings detected defects in sterilization for the surgeries including possible inadequacy in the autoclave sterilization of surgical instruments, insufficient exposure time with 2 per cent activated glutaraldehyde solution (about 15-30 minutes) for sterilizing some surgical instruments, and the use of multiple-dose intraocular irrigating solution. This outbreak of endophthalmitis emphasizes the necessity to monitor regularly the practice of sterilization/disinfection in hospitals for prevention and control of nosocomial infections.

Cataract Extraction↗

An improved operating room demagnetizer.

An operating room demagnetizer that utilized a pulsed, smoothly decaying oscillating magnetic field is described. The instrument can demagnetize a number of surgical instruments at one time and can provide instantaneous and complete demagnetization.

Magnetics↗

Competing risk factors associated with nosocomial infection in two university hospitals.

An historical cohort study of risk factors associated with nosocomial infection was conducted in two university hospitals on the East and West Coast of the USA. The purpose of the study was to estimate the relative risk ratios (RR) associated with antibiotic therapy, instrumentation, surgical operations and age with nosocomial infection, and to establish the hierarchical relationship of these factors to each other. A high risk cohort of long-staying patients (average length of stay = 30 days), was selected and each patient's chart was analysed retrospectively for infection occurrence and for risk factors. There was no significant difference between hospitals in rates of nosocomial infections, diagnostic categories and utilization of risk factors. Categorical linear regression analysis showed that a four factor model consisting of antibiotic therapy, instrumentation, surgical operations and age accounted for 95 per cent of the variation in nosocomial infection rates. Length of stay was treated as a co-dependent variable. Multivariable stratification analysis yielded aetiologic fractions of 63 per cent attributable to antibiotic therapy, 26 per cent to surgical operations, and 13 per cent to instrumentation. About half the antibiotic therapy was given on admission or at least 4 days before the first hospital-acquired infection. These data support careful assessment of prophylactic antibiotic therapy and infection control policies to reduce risk of nosocomial infection in university hospitals.

Anti-Bacterial Agents↗

Effects of chronic instrumentation on fetal growth.

Chronically-instrumented fetal sheep are a commonly used animal model for the study of fetal growth and metabolism. In the current study, we wanted to test the hypothesis that instrumentation alone would alter fetal growth patterns. Thirty-two animals in three groups were used: (i) non-instrumented animals (n = 10); (ii) instrumented with catheters in the maternal and fetal femoral artery and vein and electromagnetic flow probes on the main uterine arteries (n = 10): (iii) animals instrumented as group 2, but with the addition of a doppler flow probe on the common umbilical artery and a common umbilical vein catheter (n = 12). Animals in group 2 and 3 were monitored until 137 to 140 days of gestation, at which time they were sacrificed for fetal morphometric measurements. Instrumentation significantly (P less than 0.05) decreased fetal body weight, length, and thymus weights. Liver-to-body ratios increased (P less than 0.05) in both surgically-instrumented groups. The addition of the umbilical artery doppler flow probe and an umbilical venous catheter did not lead to any further alterations in fetal growth. The current study demonstrates that surgical instrumentation alone can lead to significant alterations in fetal growth.

Animals↗

[Eugene Koebèrlé (1828-1915), founder of modern surgery].

Eugène Koeberlé, surgeon and anatomist gained international renown due to his outstanding ability in resection of ovary cysts and in hysterectomy. He was one of the first to perform these operations successfully. He was a pioneer in asepsis and pre- and postoperative care. He also invented many surgical instruments, among them an efficient hemostatic forceps.

Female↗

Pre-preparation of the sterile instrument table for emergency cesarean section.

Cesarean section instrument tables are often not prepared in advance because of concern of contamination risk. The Association of Operating Room Nurses Standards decries the use of pre-preparation of surgical instrument tables because of this risk, although there are no scientific data to support this claim. We evaluated the contamination risk of pre-preparation of surgical instrument tables, prolonged table coverage and table uncovering using a specific technique referred to as the "sardine can roll." Colony counts were positive in only seven of 180 cultures (< or = 15 colonies per plate in each instance) from six tables evaluated after prolonged coverage or uncovering, or both. These data suggest that contamination risk is slight for the uncovering technique described herein and advance table preparation (24 hours or less, never recovered) is a reasonable clinical option in units in which table preparation reduces response time in emergent clinical situations, such as cesarean section for acute fetal distress.

Cesarean Section↗

[Robotic and telerobotic surgical systems for abdominal surgery].

The United States Food and Drug Administration (FDA) has approved four robotic surgical systems to be used in operations of clinical laparoscopy. The purpose of this article is to describe these four robotic surgical systems. In robotic laparoscopy surgery, AESOP and Endoassist replace the cameraman and provide a stable platform for the video telescope. AESOP is controlled by the surgeon's voice commands, whereas Endoassist responds to the movements of an infrared light adhered to the surgeon's head. During the telerobotic laparoscopic surgeries, the physician is seated in front of a computer console that is at a distance from the patient. The surgeon observes a virtual three-dimensional operating area and carries out the operation by controlling two tele-robotic arms, both of which hold the surgical instruments. These telerobotic arms simulate the movements of the surgeon's hands, with six degrees of freedom and two degrees of axial rotation. By combining the three-dimensional images and the movements which are similar to the manual movements of the surgical instruments, The complex laparoscopic procedures are facilitated. In June 2000, the tele-robotic surgical system Da Vinci was authorized by the FDA to act as an operating surgeon, but in October 2001, in the case of Zeus, it was only authorized to act as an assistant surgeon during laparoscopies,. Consequently, surgeons have reported great clinical experiences with Da Vinci. Tele-robotic, laparoscopic abdominal surgery is feasible, and its initial results are similar to those obtained from traditional laparoscopic surgery. Therefore, the tele-robotic and robotic surgical systems overcome some of the limitations inherent in traditional laparoscopic surgeries and they could increase the number of surgeons who could perform complex laparoscopies in the future.

Abdomen↗

The "Bernese" frameless optical computer aided surgery system.

OBJECTIVE: We report on two years of clinical experience with a frameless Computer Aided Surgery system developed in Bern, Switzerland. MATERIAL AND METHODS: Our navigation system is based on a preoperative computer-tomography (CT) scan (without markers) and an intraoperative optical tracking of head movements and of the surgical instruments. Using landmark and surface-based registration, the skull can be accurately correlated to the CT images. The three-dimensional positions of the surgical instruments, as well as the endoscopic images, are displayed in real time on a monitor. RESULTS: In the last two years, 109 computer-aided interventions have been successfully performed: 89 on the anterior skull base/paranasal sinuses, 15 on the lateral skull base, and 5 minimally invasive procedures on other locations in the skull. No complications occurred. The practical accuracy on the cadaver skull is between 0.5 mm and 1.2 mm, and the clinical accuracy is between 0. 5 mm and 2 mm. CONCLUSIONS: Our navigation system has proven its accuracy and usability. Surgeons feel very comfortable with the increased safety provided by the unequivocal identification of important anatomical structures.

Cadaver↗

Tissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levels.

BACKGROUND: Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results. METHODS: Within the context of a case-control study designed to address surgical risk of sporadic Creutzfeldt-Jakob Disease in Nordic European countries (EUROSURGYCJD Project), a strategy was adopted to categorise reported surgical procedures in terms of potential risk of Creutzfeldt-Jakob Disease acquisition. We took into account elements of biological plausibility, either clinically or experimentally demonstrated, such as tissue infectivity, PrP expression content or successful route of infection. RESULTS: We propose a classification of exposed tissues and anatomic structures, drawn up on the basis of their specific putative role as entry site for prion transmission through contact with surgical instruments that are not fully decontaminated. CONCLUSIONS: This classification can serve as a reference, both in our study and in further epidemiological research, for categorisation of surgical procedures in terms of risk level of Creutzfeldt-Jakob Disease acquisition.

Case-Control Studies↗

Intraoperative spinal navigation.

STUDY DESIGN: Review article. OBJECTIVES: To provide a detailed overview of current methods for intraoperative spinal navigation using image-guided surgical technology. SUMMARY OF BACKGROUND DATA: The development of novel intraoperative navigational techniques has been an important advancement in the field of spine surgery. These techniques, commonly referred to as image-guided surgery (IGS), provide simultaneous, multiplanar views of spinal anatomy. They can be used for detailed preoperative planning and allow the spinal surgeon to track the position of surgical instruments in real time. IGS technology can increase the accuracy of spinal instrumentation procedures and improve patient safety. METHODS: The relevant medical literature was reviewed, as was the authors' clinical and laboratory experience with intraoperative spinal navigation. RESULTS: Image-guided spinal instrumentation procedures in the cervical, thoracic, and lumbar spine have lower rates of screw misplacement than do those performed without image guidance. In a typical IGS spinal procedure, surgical instruments are tracked in the operating room, and their positions are superimposed onto preoperatively acquired computed tomography scans (CT-based image guidance) or intraoperatively acquired fluoroscopic images (virtual fluoroscopy). A new development, the combination of isocentric C-arm fluoroscopy with computer-assisted image guidance, allows the C-arm to create intraoperative CT images that can be used for image-guided navigation without the need for a surgeon-dependent registration step. Each of these technologies has distinct advantages and limitations. CONCLUSIONS: Intraoperative spinal navigation has advanced rapidly in recent years, beneficially affecting a variety of surgical procedures. Future technological developments will widen its clinical application and minimize its shortcomings.

Adult↗

Image-guided surgery of the skull base using a novel miniature position sensor.

Image-guided navigational systems have been a useful adjunct for minimally invasive surgery of the skull base. A novel miniature position sensor has been developed that uses a low magnetic field for real-time tracking of surgical instruments. The 1.7-mm-diameter sensor attached to the position and orientation system (Magellan(R), Biosense, Inc., Johnson and Johnson Co., Baldwin Park, CA) was deployed through various surgical instruments or used in a hand-held fashion with a malleable shaft probe. We report on our experience using this electromagnetic system in a series of lesions of the sella and clivus. After patient/image registration, the system was consistently accurate to within 2 mm. We have found this system to be particularly advantageous in endoscopic surgery of cystic lesions of the skull base, where access is limited and anatomy may be distorted. In three patients, this device obviated the need for an extensive external surgical approach. Case histories are presented, which illustrate the specific advantages this miniature system provides during skull base surgery.

Journal Article↗