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PubMed1984

Amino acid composition of salivary protein secreted by the parotid glands of rats in response to parasympathomimetic and sympathomimetic drugs.

Although the total protein concentration in the saliva varied markedly, depending on the nature of the stimulus, the proportions of the amino-acid residues were independent on the nature of the stimuli, where they were cholinergic, adrenergic or dopaminergic. However, the difference in protein composition of saliva previously shown in chronically isoprenaline-treated rats electrophoretically could be determined by amino-acid analysis.

Amino Acids↗
PubMed1977

Do sympathomimetic amines prevent exercise-induced asthma by bronchodilatation alone?

Seventeen patients with exercise-induced asthma were studied. Eleven patients (cases 7-17), of whom seven were atopic subjects, were given isoetharine or isoprenaline and were subsequently tested for exercise-induced asthma after bronchodilatation had ceased. In two atopic and one non-atopic patients protection was observed which could not be attributed to chance. Two of these three patients were studied again and this phenomenon was repeatable. Prevention of exercise-induced asthma 30 min after inhalation of isoetherine and sodium cromoglycate was compared in 10 patients (cases 1-10), of whom six were atopic subjects. There was no significant difference in the results and protection from isoetharine was not related to the magnitude of its bronchodilator effect. These results suggest that beta-adrenergic agonists may have both bronchodilator and other actions in exercise-iduced asthma. Whether these other actions are anti-alergic is unknown.

Adolescent↗