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At least 577 records · Page 32Linked to original sources
PubMed1990

[Smell reception and neurogenesis in the olfactory epithelium].

Experimental anosmia induced by 1% ZnSO4 solution triggered some structural and functional changes in olfactory epithelium of strain C57BL/6 mice. It was stimulated by various odors: isoamyl acetate, butyl acetate and some substances present in mice urine. It was registered that the rate of physiological responses recovery differed for various odors, being the higher in case of isoamyl acetate and butyl acetate treatment and slower with odors of the biological origin. The study of spatial distribution of the responses evoked by the odors of various quality has demonstrated that the areas of the most rapid recovery corresponded to the same areas of the epithelium of intact mice where higher responses for these stimuli were registered.

Animals↗
PubMed1987

[Smell threshold levels of substances as a criterion for evaluating the maximum permissible exposure levels].

Compared in the paper are the threshold limit values (TLV) and odour threshold concentrations (OTC) of 85 substances. As so far the generally accepted methods of odour nuisance measurements have been missing; the TLV/OTC ratio was adopted as a criterion of possible appearance of odour discomfort. The substances were divided into groups according to their feasibility of odorous nuisance. It was demonstrated that the odour discomfort might appear even with concentrations below TLVs. This particularly refers to styrene, naphthalene, CS2, pyridine and H2S.

Air Pollutants, Occupational↗
PubMedDate not supplied

[Food search by mice solving an extrapolation problem after suppression of smell by zinc sulfate].

Anosmia induced by intranasal zinc administration to mice capable of solving an extrapolation problem (search for food which disappears from animal sight in definite direction), led to disturbance of normal food searching behaviour. In anosmic mice the percentage of task solutions (correct as well as incorrect) in which the trajectory was the shortest ("goal-directed"), was significantly lower than in controls. At the same time the percentages of correct "goal-directed" choices were equal in both groups. The main differences in the number of correct task solutions were among those trials in which non-goal-directed behaviour was delivered. Thus zinc induced anosmia provokes rather severe deteriorations of food searching behaviour. The investigated group of mice possessing Robertsonian translocation Rb(8, 17) 1 IEM, reveals no disturbance of extrapolation capacity during first 20 s after task presentation. This signifies that this capacity which in this group is higher than in other mice, is not determined by peculiarities of their olfaction.

Animals↗