Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Proprioception”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 577 records · Page 32Linked to original sources
PubMed2002

Neurotrophin-3-mediated regeneration and recovery of proprioception following dorsal rhizotomy.

Injured dorsal root axons fail to regenerate into the adult spinal cord, leading to permanent sensory loss. We investigated the ability of intrathecal neurotrophin-3 (NT3) to promote axonal regeneration across the dorsal root entry zone (DREZ) and functional recovery in adult rats. Quantitative electron microscopy showed robust penetration of CNS tissue by regenerating sensory axons treated with NT3 at 1 and 2 weeks postrhizotomy. Light and electron microscopical anterograde tracing experiments showed that these axons reentered appropriate and ectopic laminae of the dorsal horn, where they formed vesicle-filled synaptic buttons. Cord dorsum potential recordings confirmed that these were functional. In behavioral studies, NT3-treated (but not untreated or vehicle-treated) rats regained proprioception. Recovery depended on NT3-mediated sensory regeneration: preventing regeneration by root excision prevented recovery. NT3 treatment allows sensory axons to overcome inhibition present at the DREZ and may thus serve to promote functional recovery following dorsal root avulsions in humans.

Animals↗
PubMed1989

Further evidence for the role of proprioception in space perception.

In this paper results are presented of errors in spatial localization found after encircling procedures for retinal detachment both in the operated and in the normal eye. Also changes in spatial localization were found in strabismus patients in which a stretch on the operated muscle was exerted after an adjustable recession. In both groups of patients a manipulation of the eye muscle was performed without inducing an eye muscle imbalance in the retinal detachment patients and without modifying the eye position in the strabismus patients in which a stretch was exerted. These data provide further evidence in favour of the role of proprioceptive information in space perception.

Humans↗
PubMed1989

Effect of botulinum toxin on extraocular muscle proprioception.

Injections of botulinum toxin type A (BoTox) in one extraocular muscle (EOM) induce long lasting paretic lengthening of the muscle permitting realignment to occur in strabismus, while eye movements appear to be unaffected after the transitory period of induced paresis. It has been hypothesized a BoTox-induced change in the spindle discharge of EOMs to explain the effect in EOM length. In decerebrate lambs and goats, first order neurons of eye muscle spindles were identified in a cellular pool located in the medial dorsolateral portion of the semilunar ganglion. The belly of the muscle to which the recorded unit belonged was infiltrated with BoTox. A decrease in afferent discharge of the spindle and in its stretch sensitivity was observed. This effect began 10-15 minutes after the injection. There was no corresponding decrease in muscle tension during the first 45 minutes. This finding suggests that the block of release of acetylcholine at motor endings is earlier and more efficacious in gamma- than in alpha-motoneurons. As a result of the proprioceptive input reduction, an unbalance between the agonist and antagonist muscles should occur favouring the ocular realignment.

Animals↗
PubMed1996

The roles of visual and proprioceptive information during motor program choice in frogs.

Previous studies have shown that leopard frogs, Rana pipiens, use tongue prehension to capture small prey and jaw prehension to capture large prey. After hypoglossal nerve transection, the frogs fail to open their mouths when attempting to feed on small prey, but open their mouths and capture large prey. Here, we investigate how visual information about the prey and proprioceptive information from the tongue interact to influence the motor program choice. Using pieces of earthworm of various sizes, we found that Rana exhibits two different behavior patterns based on prey size. The frogs captured the 1.5-cm prey using tongue prehension, whereas 2.0-cm and larger prey were captured using jaw prehension. After hypoglossal transection, the frogs never opened their mouths when they tried to feed on 1.5-cm prey. When feeding on 3.0-cm and larger prey after transection, they always opened their mouths and captured the prey using jaw prehension. When offered 2.0-cm prey, they alternated randomly between opening and not opening the mouth. Therefore, deafferentation changed the pattern of motor program choice at the behavioral border. This implies that afferents from the tongue interact with visual input to influence motor program choice.

Analysis of Variance↗
PubMed1993

Parallel processing of proprioceptive information in the terminal abdominal ganglion of the crayfish.

The processing of proprioceptive information from the exopodite-endopodite chordotonal organ in the tailfan of the crayfish Procambarus clarkii (Girard) is described. The chordotonal organ monitors relative movements of the exopodite about the endopodite. Displacement of the chordotonal strand elicits a burst of sensory spikes in root 3 of the terminal ganglion which are followed at a short and constant latency by excitatory postsynaptic potentials in interneurones. The afferents make excitatory monosynaptic connections with spiking and nonspiking local interneurones and intersegmental interneurones. No direct connections with motor neurones were found. Individual afferents make divergent patterns of connection onto different classes of interneurone. In turn, interneurones receive convergent inputs from some, but not all, chordotonal afferents. Ascending and spiking local interneurones receive inputs from afferents with velocity thresholds from 2-400 degrees/s, while nonspiking interneurones receive inputs only from afferents with high velocity thresholds (200-400 degrees/s). The reflex effects of chordotonal organ stimulation upon a number of uropod motor neurones are weak. Repetitive stimulation of the chordotonal organ at 850 degrees/s produces a small reduction in the firing frequency of the reductor motor neurone. Injecting depolarizing current into ascending or non-spiking local interneurones that receive direct chordotonal input produces a similar inhibition.

Animals↗
PubMed1990

Proprioceptive sensation in rotation of the trunk.

Proprioceptive sensation in rotation of the trunk about a vertical axis was investigated in normal human subjects. Subjects pointed at the big toe with the nose to test the accuracy of positioning of the trunk. Active rotation of the head and shoulders on the stationary hips and legs to align the nose and toe, was not significantly more accurate than moving the hips, legs and toe under the fixed head and shoulders. Passive displacements were imposed on the head and shoulders, or on the hips and legs. Thresholds for the detection of these displacements were unchanged by the exclusion of vestibular stimulation. Thresholds were highest (still less than 1 degree) at the slowest angular velocity (0.1 degree/s) and became lower as the angular velocity was increased.

Adult↗
PubMed1993

Proprioceptive guidance and motor planning of reaching movements to unseen targets.

The ability to make accurate reaching movements toward proprioceptively defined target locations was studied in seven normal subjects who were trained to reach to five different targets in a horizontal plane, with no vision of hand or target. The task consisted of moving a handle from a fixed origin to each target location, fast and accurately. Target locations were learned in training sessions that utilized acoustic cuing. Most movements were rapid, with a bell-shaped velocity profile. The error in target reproduction, which constituted the difference between the position consciously identified as the correct target location and the real target location, was calculated in each trial. This was compared with the error in preprogrammed reaching, which constituted the difference between the point in space where the initial fast movement toward the target ended and the target location. The absence of significant differences between these two error types indicated that the transformation from an internal representation of target location into a motor program for reaching to it did not introduce an additional reaching error. Learning of target locations was done only with the right hand, yet, reaching of both hands was tested. This allowed a comparison between the subjects' ability to utilize a transformed spatial code (reaching with the untrained hand) and their ability to use a direct sensory-motor code (reaching with the trained hand). While transformation of the spatial code was found to reduce it's accuracy, utilization of this code in motor programming again did not appear to introduce an additional error.

Adult↗
PubMed1995

The interaction of visual and proprioceptive inputs in pointing to actual and remembered targets.

Errors in pointing to actual and remembered targets presented in three-dimensional (3D) space in a dark room were studied under various conditions of visual feedback. During their movements, subjects either had no vision of their arms or of the target, vision of the target but not of their arms, vision of a light-emitting diode (LED) on their moving index fingertip but not of the target, or vision of an LED on their moving index fingertip and of the target. Errors depended critically upon feedback condition. 3D errors were largest for movements to remembered targets without visual feedback, diminished with vision of the moving fingertip, and diminished further with vision of the target and vision of the finger and the target. Moreover, the different conditions differentially influenced the radial distance, azimuth, and elevation errors, indicating that subjects control motion along all three axes relatively independently. The pattern of errors suggest that the neural systems that mediate processing of actual versus remembered targets may have different capacities for integrating visual and proprioceptive information in order to program spatially directed arm movements.

Adult↗
PubMed1977

Extraocular proprioceptive projections to the visual cortex.

Electrical stimulation of the intraorbital part of the motor branches of extraocular muscles, where proprioceptive fibers run, evokes responses in 25% of the units of the striate cortex of the cat. The latency ranges between 25 and 40 msec. Mechanical stretch of extraocular muscles evokes multiunit responses in the striate cortex. The response is abolished by injection of xylocaine into the stretched muscle. The suppression of the response is reversible.

Afferent Pathways↗
PubMed1981

The influence of efferent, proprioceptive, and timing factors on the accuracy of eye-hand tracking.

Oculomotor tracking of one's moving hand is considerably more accurate than tracking of an external target undergoing comparable motion. To identify the factors contributing to this enhancement of tracking accuracy, the influence of visual, proprioceptive, and efferent cues on tracking performance was assessed. Related observations were made on the influence both of linear and topological transformations between target and hand position on tracking accuracy. The experimental findings indicate that if a target light is attached to one's hand, a) the target can be tracked with comparable accuracy for active and passive limb movements, and b) when the entire hand rather than just the target light is visible, pursuit velocity is higher and more closely matches target velocity. If a linear transformation is introduced between hand and target positions, nearly identical tracking accuracy is found with voluntary and involuntary limb movements. By contrast, topological transformations degrade target tracking accuracy for passive but not for voluntary limb movements. The implications of this finding are discussed.

Adult↗
PubMed1989

Adrenergic neurons and short proprioceptive feedback loops involved in the integration of cardiac function in the rat.

Serial cryostat and paraffin-embedded sections through the atrioventricular junction of the rat heart were studied at the light-microscopic level after indirect immunohistochemical staining (tyrosine hydroxylase, neuropeptide Y, C-terminal flanking peptide of neuropeptide Y immunoreactivities) or silver impregnation. The distribution of these immunoreactivities in the Hissian ganglion (Moravec and Moravec 1984) as well as the relationships of the Hissian ganglion cells with the surrounding structures have been studied to assess its function. The results suggest that the Hissian ganglion is composed of large multipolar neurons displaying both tyrosine hydroxylase (TH) and related peptide (neuropeptide Y. C-terminal flanking peptide of neuropeptide Y) immunoreactivities. The dendritic projections of these adrenergic cells penetrate the reticular portion of the atrioventricular node and the upper segments of the interventricular septum where they constitute sensory-like corpuscles. The hypothesis that the adrenergic neurons of the atrioventricular junction are involved in short proprioceptive feedback loops necessary for beat-to-beat modulation of cardiac excitability and intracardiac conduction can thus be suggested.

Adrenergic Fibers↗
PubMed1984

Eye velocity responsiveness and its proprioceptive component in the floccular Purkinje cells of the alert pigmented rabbit.

Eye velocity responsiveness of floccular Purkinje cells was studied in alert, pigmented rabbits. Conjugate horizontal eye nystagmus was elicited by application of electric pulse trains (10-50 microA, 30 c/s) to the optic tract through chronically implanted electrodes. Purkinje cells were sampled with an extracellular microelectrode from the flocculus, and their involvement in different oculomotor functions was specified by electrical stimulation at their recording sites. At those sites where abduction of the ipsilateral eye was elicited, the discharge frequency of simple spikes usually increased during slow eye movement to the ipsilateral side and decreased during eye movement to the contralateral side in nystagmus and after-nystagmus. Within a limited range, the discharge frequency increased linearly with eye velocity, at an average rate of 1.6 impulse s-1/degree s-1. An opposite directional specificity (decrease in ipsilateral and increase in contralateral eye movement) and directional non-specificity were common at other floccular sites where local stimulation elicited downward or no eye movement. Retrobulbar anesthesia of proprioceptive afferents from one eye reduced the eye velocity responsiveness of Purkinje cells in the ipsilateral flocculus by 31%, but did not affect their responsiveness in the contralateral flocculus. These observations indicate that eye velocity input to the rabbit flocculus arises partly from peripheral receptors but mainly from the central oculomotor system, and that responsiveness of Purkinje cells to the input is organized specifically according to their functional involvement.

Animals↗
PubMed1996

Availability of visual and proprioceptive afferent messages and postural control in elderly adults.

The ability of young and elderly adults to keep a stable upright posture while facing changes in the availability of visual and/or propriomuscular information was investigated. The two sensory sources of information were alternatively available and withdrawn, jointly and separately, during 10-s alternating sequences. Vision was modified by means of liquid-crystal goggles, and proprioception was altered by means of tendon vibration of both antagonistic ankle muscles. Elderly adults were less stable than young adults when vision was withdrawn. Both groups were greatly affected when propriomuscular inputs were altered by vibration. Under constant visual conditions and following a propriomuscular perturbation (i.e., vibration), elderly adults were unable to take advantage of the reinsertion of propriomuscular inputs. They showed a transient, decreased stability and were unable to fully recover during a 10-s period, whereas young adults were able to rapidly integrate the information to stabilize their posture. When both propriomuscular and visual inputs were withdrawn and concurrently reinserted, the elderly adults did not show a transitory increase in the velocity of the center of foot pressure. The present results extend findings on the inability of elderly adults to reconfigure rapidly the postural set following reinsertion of sensory inputs. The results also suggest that elderly adults have difficulties in taking advantage of sensory redundancy in postural control.

Adult↗
PubMed1994

The interactive contribution of neck muscle proprioception and vestibular stimulation to subjective "straight ahead" orientation in man.

Seventeen normal subjects were asked to direct a laser point to the position they felt to lie exactly straight ahead of their body. Subjects were seated in complete darkness in an approximately spherical cabin in an upright position with the orientation of the trunk and head aligned. For both the horizontal and vertical plane, "straight ahead" judgements were closely scattered around the objective straight ahead body position. Posterior neck muscle vibration as well as caloric vestibular stimulation with ice water led to (1) an apparent motion and horizontal displacement of a stationary visual target to the side opposite to stimulation and (2) a horizontal deviation of subjective "straight ahead" perception toward the side of stimulation. Only those subjects who experienced an illusion of target motion also showed a deviation of their subjective body orientation. No systematic effect of a displacement of subjective body orientation in the vertical plane was detected. When vestibular stimulation and neck muscle vibration were combined their effects were additive, i.e. the horizontal deviation of subjective body orientation observed when either type of stimulation was applied in isolation, was linearly combined either by summation or by cancellation. The present results clearly support the assumption that afferent visual, vestibular and proprioceptive input converge to the neural generation of an egocentric, body-centred coordinate system that allows us to determine our body position with respect to visual space.

Adult↗
PubMed1988

Proprioception in the neck.

Proprioception in the neck was investigated in normal human subjects. Three experiments studied rotation of the head about a vertical axis on the body. Accuracy of pointing, thresholds for detection of passive movement, and control of fine movement were tested. Comparison of the accuracy of pointing at the big toe with the nose and with the arm, showed a smaller scatter of angular misalignments when pointing with the arm. However, the arm pointed systematically off target. Pointing at the target toe by turning the head was not significantly more accurate than aligning the nose and toe by turning the chair and body with the head fixed. The highest threshold found for the detection of the direction of passive movement of the head relative to the body was 1.4 degrees angular displacement. Thresholds were highest at the slowest angular velocity and dropped as angular velocity increased. When the head was turned on the body thresholds were lower than when the body was turned and the head held still. Control of fine angular movements of the head and of the distal phalanx of the right thumb were compared by measuring subjects' accuracy in guiding a cursor through a path on a computer screen by turning the head or moving the thumb. The thumb was found to be better controlled than the head.

Humans↗
PubMed1996

Proprioception in the nearly extended knee. Measurements of position and movement in healthy individuals and in symptomatic anterior cruciate ligament injured patients.

Proprioception of the knee was measured in 19 healthy individuals to evaluate whether there were any differences between extension and flexion movements from two different starting positions. The threshold before detecting a passive movement, visual estimation on a protractor of a passive change in position (30 degrees angular change) and active reproduction of the same angular change were registered. The reference population was tested twice to study normal variation and reproducibility, followed by the evaluation of 20 patients with chronic, symptomatic and unilateral anterior cruciate ligament (ACL)-deficient knees. In the normal population no differences were found between the right and the left leg, men and women, or measurements made at the first and at the second test occasion. The thresholds from a starting position of 20 degrees were lower for extension than for flexion. When comparing the thresholds for extension between the 20 degrees and the 40 degrees starting position, lower values were found in the more extended position. The thresholds for flexion were lower from the 40 degrees starting position than from the 20 degrees starting position. The active reproduction of an angular change of 30 degrees was more accurate during flexion (30 degrees-60 degrees) than during extension (60 degrees-30 degrees). There were no differences in the reproduction tests or in thresholds from the 40 degrees starting position between the patients and the normal group, but the patients had higher thresholds from the 20 degrees starting position, in movements towards both extension 1.0 degree (range 0.5 degree-12.0 degrees) and flexion 1.5 degrees (range 0.5 degree-10.0 degrees) than the normal group 0.75 degree (range 0.5 degree-2.25 degrees) (P = 0.01) and 1.0 degree (range 0.5 degree-3.0 degrees) (P = 0.06), respectively. Thus, information of passive movements in the nearly extended knee position was more sensitive towards extension than towards flexion in threshold tests and the sensitivity improved closer to full extension, which implies a logical joint protective purpose. In this nearly extended knee position, which is the basis for most weight-bearing activities, patients with symptomatic ACL-deficient knees had an impaired awareness in detecting a passive movement. There were no differences in the more flexed position or in the reproduction tests between the patients and the normal group, and reproduction tests in the present form seem less appropriate to use in the evaluation of ACL injuries.

Adult↗
PubMed2004

[Standing stability in children- and young adults. Influence of proprioceptive, visual and vestibular systems in age- and sex dependent changes].

BACKGROUND: The maintenance of balance while standing is ensured by means of a sensory motor control system. As the development of sensory organization on posture control in children is not clear at this time, the aim of this study was to analyse the significance of each sensory component in relation to age and sex. SUBJECTS AND METHOD: A total of 128 children between the ages of 3 and 16 years and 23 adults were examined using the Sensory Organization Test (EquiTest). RESULTS: Age-related changes during the test procedure showed a developmental tendency of the sensory motor process. The influence of the proprioceptive function on stance stability seemed to be completely developed between 3-4 years. The visual and vestibular afferences reached the adult level between 15-16 years with differences between girls and boys. CONCLUSION: Age-related evaluation of the postural mechanisms can be used for differentiation between physiological and pathological results in balance control as well as for monitoring therapy progress in the context of, for example, hyperactivity or learning disability.

Adaptation, Physiological↗