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At least 577 records · Page 32Linked to original sources
PubMed1975

Partial xenon coagulation of net in histoplasmic choroiditis.

Ten patients with ocular histoplasmosis (photocoagulated 17 times) were retrospectively selected, in what was considered an unbiased manner, for examination of their response to partial xenon photocoagulation of their neovascular nets. Of the 17 photocoagulations, the part of the neovascular net not coagulated remained the same in 7, was stimulated in 5, and suppressed in 5. This distribution was not statistically different from a control group receiving corticosteroids alone. A direct relation of suppression of the uncoagulated part of the net with the distance of this coagulation from the fovea was demonstrated.

Blood Vessels↗
PubMed1988

Alternatives in the treatment of hemorrhoidal disease.

Pain, bleeding, protrusion, soilage, itching, and burning are anorectal complaints associated with hemorrhoidal disease. Although hemorrhoidectomy remains the treatment of choice for grade 3 and 4 hemorrhoids, symptoms can be controlled short of hemorrhoidectomy, the alternative methods being effective in lesser degrees of involvement, such as grades 1, 2, and 3. Cryosurgery and dilation are fading alternatives; laser is becoming more widely used, but results have not been fully evaluated. Sclerotherapy, rubber band ligation, and infrared coagulation are also effective alternatives for patients who demand nonsurgical therapy.

Cryosurgery↗
PubMed1987

Venous lakes: treatment by infrared coagulation.

A new treatment for venous lakes (Bean and Walsh, 1956) has been devised using an infrared coagulator. The solid light guide with its sapphire cap enables the ectatic vessels to be compressed prior to coagulation, minimising the energy required to destroy the vessels. We have successfully treated 10 lesions with a pulse duration of 1.125 seconds.

Humans↗
PubMed1989

Animal experiments for the determination of an optimal wavelength for retinal coagulations.

The retina of rabbits was coagulated with different wave-lengths (570-630 nm) using a tunable dye laser with Rhodamin 6G. To achieve comparable ophthalmoscopic appearance the intensity of the laser beam was varied with neutral filters of varying absorption. Histologic examination of fresh coagulation effects and 3-week-old coagulation scars showed no difference in relation to the wave-length used. Theoretically, 577 nm seems to be a particularly useful wavelength for the treatment of a wide variety of retinal lesions because it is not absorbed in xanthophyll and penetrates opacities of the optic media better than argon blue green. Furthermore, it is absorbed maximally in hemoglobin, making it particularly suitable for the coagulation of blood vessels.

Animals↗
PubMed1990

A controlled study of the argon beam coagulator for partial nephrectomy.

An argon beam coagulator was evaluated in 25 canine partial nephrectomies to determine its hemostatic capabilities, safety and degree of thermal injury to renal parenchyma. Comparison was made with a control group of seven partial nephrectomies performed by standard technique. In both groups the procedure was performed without renal cooling or clamping of the renal artery. The argon beam coagulator was operated with a power output of 130 watts. Mean operative time for partial nephrectomy was 22 minutes in the control group versus 10 minutes when the argon coagulator was used (p less than 0.001). Mean blood loss was 276 cc by standard technique but only 135 cc with the argon coagulator (p less than 0.001). A regular eschar with a mean depth of tissue necrosis of 2.4 mm. was observed with the argon coagulator.

Animals↗
PubMed1986

Comparison of the infrared coagulator and the carbon dioxide laser in the removal of decorative tattoos.

A comparative study of the removal of decorative tattoos by the infrared coagulator and the CO2 laser was performed. The comparison was made by following the parameters of length of healing time, postoperative pain, presence of residual pigment, and tendency for scarring. The results showed that the infrared coagulator had the advantages of a more rapid healing time, an easier-to-care-for treatment site, and an equivalent cosmetic result in comparison with the CO2 laser. The CO2 laser had the advantage of total pigment removal in a single treatment, whereas the infrared coagulator often left residual pigment.

Adult↗
PubMed1988

Local epinephrine injection improves the therapeutic effect of Nd-YAG laser treatment of arterial peptic ulcer bleeding.

Nd-YAG laser therapy has been shown to be effective in the treatment of gastrointestinal ulcer bleeding. However, a breakdown by bleeding severity shows that its benefit is doubtful in bleeds classified as Forrest Ia and IIa. In a prospective study, we therefore tested a new therapeutic approach combining epinephrine injection into the bleeding site, with subsequent laser coagulation. Thirty-two patients with Forrest Ia and IIa bleeding from gastric or small intestinal ulcers were compared with 51 own historical controls treated by laser coagulation alone. In the combined therapy group, a significantly higher rate of permanent hemostasis was achieved, and mortality and frequency of emergency surgery were significantly reduced. Furthermore bleeding recurred more rarely and only during the later course of the disease. Finally, following epinephrine injection fewer Forrest IIa ulcer bleeds were reactivated by laser treatment, and all of these bleeds were stopped by further laser coagulation. Overall, our results demonstrate a clear-cut therapeutic improvement when laser coagulation is preceded by local epinephrine injection.

Combined Modality Therapy↗
PubMed1992

[Results of the treatment of ocular toxoplasmosis in personal experience].

Ocular toxoplasmosis manifested itself in following clinical forms: as central serous chorioretinitis, pars planitis, iritis, intrabulbar neuritis and central retinal degeneration. The diagnosis was based on the clinical picture, serological examinations, the course of the disease and the effect of the specific treatment. The authors used piridimide++ compounds, sulfonamides, steroids, folic acid and Tavegyl, Decaris as well as photo-coagulation. The efficacy of all these methods was compared.

Adult↗
PubMed1991

[The use of the laser scalpel in surgery of the spleen].

The CO2 laser was used to arrest bleeding from traumatic wounds of the spleen in 24 patients. The success of laser coagulation was determined by the qualification of the surgeon who performed the operation and his skill in working with a laser scalpel. Comparative analysis of the intraoperative aspects and operative outcomes with those in 60 patients who underwent splenectomy (57) and suturation (3) showed the marked advantages of laser coagulation which allowed the spleen to be preserved in 63% of cases.

Adolescent↗
PubMed2006

Photochemical treatment of plasma with amotosalen and long-wavelength ultraviolet light inactivates pathogens while retaining coagulation function.

BACKGROUND: The INTERCEPT Blood System, a photochemical treatment (PCT) process, has been developed to inactivate pathogens in platelet concentrates. These studies evaluated the efficacy of PCT to inactivate pathogens in plasma and the effect of PCT on plasma function. STUDY DESIGN AND METHODS: Jumbo (600 mL) plasma units were inoculated with high titers of test pathogens and treated with 150 micromol per L amotosalen and 3 J per cm(2) long-wavelength ultraviolet light. The viability of each pathogen before and after treatment was measured with biological assays. Plasma function was evaluated through measurement of coagulation factors and antithrombotic protein activities. RESULTS: The levels of inactivation expressed as log-reduction were as follows: cell-free human immunodeficiency virus-1 (HIV-1), greater than 6.8; cell-associated HIV-1, greater than 6.4; human T-lymphotropic virus-I (HTLV-I), 4.5; HTLV-II, greater than 5.7; hepatitis B virus (HBV) and hepatitis C virus, greater than 4.5; duck HBV, 4.4 to 4.5; bovine viral diarrhea virus, 6.0; severe acute respiratory syndrome coronavirus, 5.5; West Nile virus, 6.8; bluetongue virus, 5.1; human adenovirus 5, 6.8; Klebsiella pneumoniae, greater than 7.4; Staphylococcus epidermidis and Yersinia enterocolitica, greater than 7.3; Treponema pallidum, greater than 5.9; Borrelia burgdorferi, greater than 10.6; Plasmodium falciparum, 6.9; Trypanosoma cruzi, greater than 5.0; and Babesia microti, greater than 5.3. Retention of coagulation factor activity after PCT was expressed as the proportion of pretreatment (baseline) activity. Retention was 72 to 73 percent of baseline fibrinogen and Factor (F)VIII activity and 78 to 98 percent for FII, FV, FVII, F IX, FX, FXI, FXIII, protein C, protein S, antithrombin, and alpha2-antiplasmin. CONCLUSION: PCT of plasma inactivated high levels of a wide range of pathogens while maintaining adequate coagulation function. PCT has the potential to reduce the risk of transfusion-transmitted diseases in patients requiring plasma transfusion support.

Animals↗
PubMed1991

The effect of wavelength on glial fibrillary acidic protein immunoreactivity in laser-induced lesions in rabbit retina.

Rabbit retinas were treated with low-intensity laser coagulation at five different wavelengths. Using an indirect immunocytochemical method, the retinas were stained for glial fibrillary acidic protein (GFAP) at 2, 4, 21 and 32 days after coagulation such that we could follow GFAP expression in the Müller cells during retinal repair. GFAP-positive staining was found in the end feet of the Müller cells at 2 days after laser coagulation. GFAP immunoreactivity was observed throughout the Müller cells, surrounding the central necrotic tissue, at days 4, 21 and 32 after laser coagulation. Scar tissue in the subretinal space at days 21 and 32, which was more pronounced for the longer wavelengths produced by the Krypton and Nd-YAG lasers, also showed GFAP immunoreactivity. The Müller cells remained GFAP-immunoreactive for at least 32 days after laser coagulation.

Animals↗