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At least 577 records · Page 32Linked to original sources
PubMed1978

Bovine experimental paracoccidioidomycosis intradermic test standardization.

Three intratesticulary inoculated bovines revealed to be susceptible to experimental paracoccidioidomycosis. The experimental infection was self limited with no tendency to dissemination during a follow up period of five months. The histopathologic lesions characterized by granulomatous inflammatory foci, associated or not to necrosis, were found in the testicles, spermatic cords and testicular tunicae. In some of both lesions types the yeast cells of P. brasiliensis were present. The experimental infection did not cure in a follow up period of five months. The immunological response either cellular or humoral were delayed in relation to what happens in other animal species. The three experimentally infected bovines were utilized for some standardization of the paracoccidioidin intradermic test. A type and dose of an antigen which gives a clear reading for the positive tests was determined. The humoral responses were detected mainly by the complement fixation reaction. It was not possible to demonstrate humoral antibodies by the agar immunodiffusion test.

Animals↗
PubMed1975

Therapy of chorioretinitis presumed to be caused by histoplasmosis.

We acknowledge that for most patients with istoplasmic chorioretinitis, the only treatment available is steroids. We agree with Schlaegel that steroids have to be used in adequate doses and for long periods of time. Alternate-day treatment should be instituted as soon as possible. Because it takes the adrenals 10 days to to weeks to be suppressed by sterid therapy, we treat our patients with daily doses for as short a time as possible and then witch over o alernate-day treatment. A short-acting steroid such as prednisone, prednisolone, or methylprednisolone should be used at the outset if long-term therapy is necessary and one anticipates using alternate-day therapy...

Adrenal Cortex Hormones↗