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At least 577 records · Page 32Linked to original sources
PubMed2000

Myxoid chondrosarcoma of the sphenoid sinus and chondromyxoid fibroma of the iliac bone: cytomorphologic findings of two distinct and uncommon myxoid lesions.

Myxoid chondrosarcoma (MCS) and chondromyxoid fibroma (CMF) are two uncommon myxoid cartilaginous neoplasms with distinct cytologic features, histologic patterns, and immunoprofiles. Because these neoplasms have characteristic biological behaviors and management, their correct diagnosis is crucial to avoid debilitating and unnecessary surgical procedures. We report the imprint cytology (IC) preparation findings along with the differential diagnosis in one case each of myxoid chondrosarcoma and chondromyxoid fibroma of the splenoid sinus and iliac bone, respectively. The two great mimickers for these neoplasms, chordoma and chondrosarcoma, represent difficult diagnostic challenges, especially when MCS and CMF occur in unusual locations. IC in conjunction with the clinical and radiologic findings can provide a rapid preliminary intraoperative diagnostic interpretation which can aid in planning the immediate surgical management, as well as guide specific tissue triage for key ancillary studies such as electron microscopy and cytogenetic analyses. To the best of our knowledge, there have been no cytologic reports of MCS of the sphenoid sinus and CMF of the iliac bone.

Adult↗
PubMed2003

Aspiration cytology of ameloblastic fibroma: a diagnostic challenge.

Ameloblastic fibroma of the jaw is a rare, benign mixed odontogenic tumor, having little tendency for local invasion and a low recurrence rate. Cytologic distinction from ameloblastoma, ameloblastic fibrosarcoma, and intraosseous adenoid cystic carcinoma is necessary, in view of the different biologic behavior. A painful, slow-growing swelling of the jaw in a 5-yr-old child clinicoradiologically considered as a benign cystic lesion was aspirated. Sheets of small monomorphic epithelial cells with peripheral palisading by columnar cells were seen on cytology smears. The striking feature was central hyaline globules in some tubules. A cytologic possibility of adenomatoid odontogenic tumor was suggested. Histopathology, however, confirmed it to be an ameloblastic fibroma.

Ameloblastoma↗
PubMed1980

Unusual leiomyoma of vulva with fibroma-like pattern and pseudoelastin production.

A unique case of a 71-year old woman with an unusual fibroma-like leiomyoma of the vulva in the region of the left Bartholin's gland is reported. Light microscopically the tumor resembled a fibroma, but electron microscopically the cells corresponded to modified smooth muscle cells. The great number of vessels and their intimate relation to the tumor cells is remarkable. In the intercellular space granular and fibrillar pseudoelastic material was found and thus the presence of collagen type III in addition to type I is suggested. In the region of the right Bartholin's gland a mesenchymal proliferation with similar histological features was seen but there was more resemblance to a conventional leiomyoma. The histogenesis remains obscure so that the designation of these lesions should include light microscopic and electron microscopic appearances as well as localization.

Aged↗
PubMed1986

Aggressive cementifying fibroma of the maxilla.

The cementifying fibroma is a benign fibro-osseous lesion. Its usual location is in the mandible while rare sites of involvement have been the maxilla and ectopic locations. These tumors are generally believed to originate from the connective tissue of the periodontal ligament. Clinically, lesions are usually asymptomatic, slow-growing, and well-circumscribed. However, in very few cases, particularly in younger patients, these tumors have demonstrated and apparent aggressive course of development. We describe a case of an aggressive cementifying fibroma of the maxilla in a middle-aged male. The pathogenesis of the tumor is discussed, and the need for appropriate surgical management is emphasized.

Humans↗
PubMed1984

Ameloblastic fibrosarcoma in the maxilla, malignant transformation of ameloblastic fibroma.

This report presents a fatal case of ameloblastic fibrosarcoma arising from an ameloblastic fibroma, originating in the maxilla of 19-year-old Japanese male. An analysis of previously reported fatal cases of ameloblastic fibrosarcoma is included. In the course of the disease, the mesenchymal component of ameloblastic fibroma showed a dramatic histopathological transformation into sarcoma following multiple recurrence and the patient died of uncontrollable local infiltration of the cranial base. Although many cases have seemed to show disappearance of the epithelial component as malignant transformation progressed, many benign appearing ameloblastoid epithelial masses were scattered throughout the sarcomatous area even in the fatal stage in the present case. No distant metastases were found at autopsy. During multiple recurrences of the lesion, a little dysplastic dentin which was closely associated with both epithelial and mesenchymal components was found, though it could not be observed in autopsy material. Ultrastructural findings in autopsy material showed that the mesenchymal component consisted of undifferentiated mesenchymal cells, fibroblastic and fibrocytic cells with marked cellular and nuclear pleomorphism and that the epithelial component closely resembled the enamel organ.

Adult↗
PubMed1997

[Ameloblastic fibroma of the maxilla].

Ameloblastic fibromas are rare benign odontogenic tumours, which appear preferentially in adolescents and young adults. They are most often found in the mandible. The present case report describes a 40-year-old patient with an ameloblastic fibroma in the upper jaw, an extremely rare site. The diagnosis, differential diagnosis, histology and therapeutic procedure are described.

Adult↗
PubMed1997

[Nuchal fibroma].

Nuchal fibroma is a fibrolipoma-like soft tissue mass, located on the back and neck of middle-aged men. Clinically it presents as adiffuse indurated subcutaneous swelling and, sometimes painful and inflamed. Since the first descriptions, by Enzinger and Weiss and Lister et al. both in 1988, under the name "collagenosis nuchae", only 15 additional cases have been reported. Nonetheless, the lesion is comparatively common. We report another case of nuchal fibroma emphasizing the distinctive clinical and histopathological features of this lesion and its differential diagnosis.

Biopsy↗
PubMed2002

Intracortical chondromyxoid fibroma of humerus.

The clinicoradiologic and pathologic aspects of an intracortical, diaphyseal chondromyxoid fibroma of the humerus are reported. Because of the location of the lesion, the possibility of chondromyxoid fibroma was not considered radiologically. The diagnosis was made only after histologic examination of tissue obtained via an open biopsy, which led to the appropriate treatment, surgical curettage.

Adult↗
PubMed1996

Chondromyxoid fibroma of the foot.

Chondromyxoid fibroma is a rare benign cartilaginous tumour seen most frequently around the knee in children and young adults. Up to 17% occur in the foot, where more aggressive appearances have been reported. Four cases of chondromyxoid fibroma in the forefoot are presented, demonstrating the wide range of radiological appearances of this primary tumour. Three of the four tumours recurred, one at 19 years after the surgery. These cases illustrate the need for thorough preoperative assessment to ensure complete surgical resection in an attempt to reduce the incidence of local recurrence.

Adolescent↗
PubMed1996

Chondromyxoid fibroma of the sternum.

We report the fourth case of chondromyxoid fibroma of the sternum described in the literature. The clinical, radiographic, pathologic and treatment aspects of this case are presented, and the literature on chondromyxoid fibroma in this unusual location is reviewed.

Adult↗
PubMed1997

Juxtacortical chondromyxoid fibroma: imaging findings in three cases and a review of the literature.

Chondromyxoid fibroma is a rare bone neoplasm characterized by chondral, myxoid and fibrous differentiation. Uncommon locations include the bone surface. Roentgenography, MRI and ultrasound can suggest the diagnosis. However, diagnosis of chondromyxoid fibroma is rarely made prior to biopsy. We present the radiologic and pathologic findings in three patients with this tumor and a review of the literature.

Adult↗
PubMed2000

Chondromyxoid fibroma of the temporal bone: CT and MRI findings.

We present the case of a 44-year-old woman with chondromyxoid fibroma of temporal bone origin. Since this is the least common bone tumor of cartilaginous origin, it is highly unusual to find this tumor in the skull. In fact, the literature describes 18 cases of this form of neoplasia arising in the skull, only 4 of these having originated in the temporal bone. To date, the radiological features of these tumors, and especially features detected using the latest imaging modalities, have not been described in detail. This report is unique in that it is the first to present a case of chondromyxoid fibroma of the temporal bone accompanied by detailed CT and MRI findings.

Adult↗
PubMed2000

Autogenous bone marrow graft to non-ossifying fibroma with a pathologic fracture.

Non-ossifying fibroma with a pathological fracture of the radius in a 10-year-old girl was successfully treated by curettage and autogenous bone marrow graft. The lesion was completely replaced by normal bone at 1 year after the operation. Autogenous bone-marrow graft was considered to be a useful method for the treatment of non-ossifying fibroma with minimal morbidity of the graft-harvesting site.

Bone Diseases, Developmental↗
PubMed1981

An analysis of the interrelationship of the mixed odontogenic tumors--ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas.

The mixed odontogenic tumors--ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas--represent a group of lesions of which some are neoplastic and some are hamartomatous. Regarding data on age, sex distribution, and site of occurrence of the various lesions, it was concluded that the ameloblastic fibroma represents a separate entity that does not develop into a more differentiated odontogenic lesion and that the ameloblastic fibro-odontoma is an immature complex odontoma. Moreover, it was noted that the distribution according to site of the ameloblastic fibro-odontoma and complex odontoma was dependent on age, both lesions showing a more posteriorly located site of predilection with increasing age. Finally, it is supposed that age-related factors determine whether an aberrant development of the odontogenic tissues exhibits a hamartomatous or a neoplastic nature.

Adolescent↗
PubMed1986

Stereologic analysis of histologic parameters of a twice-recurrent ameloblastic fibroma.

The behavior of the odontogenic tumors with time remains a subject of controversy. A case of ameloblastic fibroma with two recurrences is presented. It represents further evidence of the ability of the ameloblastic fibroma to recur, although recurrences may have resulted from incomplete initial removal. The volumetric density of the odontogenic epithelium (Vvoe) was evaluated stereologically for the initial tumor and for each recurrence. Analysis of the results shows that a maturation process, which was statistically significant, occurred between the initial tumor and the first recurrence but not between the first and second recurrences.

Child↗
PubMed1987

Central granular cell odontogenic fibroma.

First described in 1962, the so-called granular cell ameloblastic fibroma has been a rarely reported benign odontogenic tumor. On reviewing the literature, we have identified eight previously reported cases. All cases involved well-circumscribed radiolucencies in women who ranged in age from 53 to 65 years. Seven lesions occurred in the posterior body of the mandible, and one occurred in the premolar region of the maxilla. All lesions were treated with surgical excision, and no recurrences were identified during follow-up periods of 6 to 144 months. Two additional cases also appear to represent instances of this neoplasm, which bring the total number identified to ten. We describe the clinical, radiographic, and histopathologic features of two additional cases and suggest reasons the tumor should be referred to as central odontogenic fibroma, granular cell variant.

Adult↗
PubMed1988

Multiple dental follicles with odontogenic fibroma-like changes (WHO type).

A 15-year-old boy, in the case presented in this article, had 13 unerupted teeth, each associated with hyperplastic pericoronal tissue that showed histologic features suggestive of the WHO type of odontogenic fibroma. The etiology, clinical features, radiographic findings, and histopathology of the odontogenic fibroma are reviewed. It is suggested that the unusual pericoronal findings represent a hamartomatous change.

Adolescent↗