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[Colposcopic evaluation of cervical epithelium during oral contraception. A controlled clinical study].

The Authors report the results of a controlled clinical study by means of colposcopy, cytology and target biopsy on 525 oral contraceptive (O.C.) users and 519 controls. Except for age class 31-35, more iodine dark cervices are found in cases, more iodine light (AnTZ and/or ectropion) in controls. The difference, although not statistically significant, suggests a protective role of O.C. on cervical epithelia. In 34 women (15 cases and 19 controls) CIN has been diagnosed. O.C. users show a more favorable situation, except for ages over 30 exposed to O.C. for less than 24 months. The Authors hypothesize a protective role of O.C. in younger women. While women aged 30 or more still appear protected when exposed to O.C. for more than two years (possibly from younger ages), these results suggest some caution in beginning oral contraception after the 30th year of age.

Adult↗
PubMed1988

Colposcopic management of abnormal cervical cytology in pregnancy.

Two hundred sixty-five pregnant women with abnormal Papanicolaou smears underwent colposcopy; 248 of them underwent directed cervical biopsies. Correlation of cytology with histology indicated concordancy within one grade in 202 of 241 patients (84%). Cytology was significantly more advanced than directed cervical biopsy in 15% and significantly less advanced in 1%. None of the 163 patients with moderate dysplastic cytology or less had microinvasive or invasive disease. Cervical conization was performed on 23 women, 4 of whom underwent modified radical hysterectomy for microinvasive carcinoma. Sixteen of 18 patients undergoing conization in pregnancy were available for postpartum follow-up and had persistent cervical dysplasia. Of 242 women followed conservatively, without pregnancy conization, 88 underwent postpartum evaluation. There were no false negatives in the antepartum evaluation of malignancy.

Adolescent↗
PubMed1988

Colposcopic findings in women with vulvar pain syndromes. A preliminary report.

Of 105 women referred for vulvar discomfort, 77 had idiopathic vulvodynia (pain, dyspareunia, burning or pruritus not explicable by a standard diagnosis). Physical examination showed that patients with those complaints fell into one of two categories: (1) diffuse, irritative acetowhitening of both the cutaneous and mucosal surfaces (42 patients), and (2) painful vestibular erythema, with or without acetowhitening (35 patients). The physical findings appeared to be predictive of therapeutic response. Among women with only diffuse, irritative acetowhitening, low-dose topical 5 fluorouracil was about 75% effective in milder cases, while CO2 laser photovaporization controlled 77% of cases with moderate and severe symptomatology. In contrast, medical regimens succeeded in just 8% of women with painful vestibular erythema, and only 59% were cured by hymenal resection. Several of the remaining cases have responded to selective argon laser photocoagulation of the hyperemic blood vessels within symptomatic areas.

Adolescent↗