Biopharmaceutical studies on factors affecting rate of absorption of drugs. I. Absorption of salicylamide in micellar solution.
Explore the source record for details and available documents.
Absorption↗
SEARCH · Search PubMed
Results for “BIOPHARMACEUTICS”
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Biopharmaceutical studies on factors affecting rate of absorption of drugs. II. Further investigation of absorption of drugs in micellar solution.
Explore the source record for details and available documents.
Animals↗
Studies on the pharmaceutical potentiation of drugs. IV. Biopharmaceutical study on the derivatives of p-aminosalicylic acid.
Explore the source record for details and available documents.
Aminosalicylic Acids↗
Studies on absorption and excretion of drugs. XXIX. Biopharmaceutical studies on guaiacol glycerol ether and related compounds. I. Blood level of guaiacol glycerol ether in rabbit and its binding with serum proteins.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical studies on guiacol glycerol ether and related compounds. 3. Metabolites of guaiacol glycerol ether and its mononicotinate. 1.
Explore the source record for details and available documents.
Acetates↗
Biopharmaceutical studies on guaiacol glycerol ether and related compounds. II. Hypocholesteremic action. 1.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical study of the hepato-biliary transport of drugs. I. Hepato-biliary transport of non-metabolizing organic anionic compounds in rat.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical study of the hepato-biliary transport of drugs. III. Binding characteristics of bromphenol blue and amaranth to the liver cytoplasmic Y and Z binding proteins in vitro.
Explore the source record for details and available documents.
Amaranth Dye↗
Biopharmaceutical study of the hepato-biliary transport of drugs. IV. Development of the method to investigate the process of the active secretion of drugs from the hepatocytes into the bile canaliculi and its application to the biliary excretion of organic anions in rat.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical study of the hepato-biliary transport of drugs. V. Hepatic uptake and biliary excretion of organic cations.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical study of the hepatobiliary transport of drugs. VI. Inhibition of active biliary excretion of organic cations by retrograde infusion.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical study of the hepato-biliary transport of drugs. VII. Improvement of the bioavailability of rifampicin by dosage form design.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical study of the hepato-biliary transport of drugs. VIII. Investigation of Hepatic uptake of organic cations by portal infusion.
Explore the source record for details and available documents.
Animals↗
Biopharmaceutical studies on the effect of some topical vehicles on human skin.
Explore the source record for details and available documents.
Administration, Topical↗
Biopharmaceutical study on the oral and rectal administrations of enamine prodrugs of amino acid-like beta-lactam antibiotics in rabbits.
Explore the source record for details and available documents.
Administration, Oral↗
Biopharmaceutical studies of thiazide diuretics. II. High-performance liquid chromatographic method for determination of hydrochlorothiazide in plasma, urine, blood cells and bile.
Explore the source record for details and available documents.
Adolescent↗
[Biopharmaceutical studies on molecular mechanisms of membrane transport].
By incorporating the transporter-mediated or receptor-mediated transport process in physiologically based pharmacokinetic models, we succeeded in the quantitative prediction of plasma and tissue concentrations of beta-lactam antibiotics, insulin, pentazocine, quinolone antibacterial agents, and inaperizone and digoxin. The author's research on transporter-mediated pharmacokinetics focuses on the molecular and functional characteristics of drug transporters such as oligopeptide transporter, monocarboxylic acid transporter, anion antiporter, organic anion transporters, organic cation/carnitine transporters (OCTNs), and the ATP-binding cassette transporters P-glycoprotein and MRP2. We have successfully demonstrated that these transporters play important roles in the influxes and/or effluxes of drugs in intestinal and renal epithelial cells, hepatocytes, and brain capillary endothelial cells that form the blood-brain barrier. In the systemic carnitine deficiency (SCD) phenotype mouse model, juvenile visceral steatosis (jvs) mouse, a mutation in the OCTN2 gene was found. Furthermore, several types of mutation in human SCD patients were found, demonstrating that OCTN2 is a physiologically important carnitine transporter. Interestingly, OCTNs transport carnitine in a sodium-dependent manner and various cationic drugs transport it in a sodium-independent manner. OCTNs are thought to be multifunctional transporters for the uptake of carnitine into tissue cells and for the elimination of intracellular organic cationic drugs.
ATP Binding Cassette Transporter, Subfamily B, Mem↗
[Biopharmaceutical studies of drugs. II. The competitive inhibition of pentazocine glucuronidation by salicylamide in vitro (author's transl)].
Explore the source record for details and available documents.
Animals↗