Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “heart attack”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 559 records · Page 31Linked to original sources
PubMed1989

A community-wide perspective of secular trends in the therapeutic management of patients with acute myocardial infarction. The Worcester Heart Attack Study.

As part of an ongoing community-wide study of time trends in the incidence and case-fatality rates of patients hospitalized with acute myocardial infarction (MI) in 16 Worcester, Mass., metropolitan hospitals during the calendar years 1975, 1978, 1981, and 1984, changes over time in the therapeutic management of 3,263 patients with validated acute MI were examined. Beta-blocker and nitrate therapy use increased consistently and dramatically. Use of antiplatelet agents was inconsistent, while use of digoxin remained stable. Use of antiarrhythmic medications other than lidocaine decreased consistently while lidocaine use increased between 1975 and 1978 and then leveled off to being used in approximately 45% of hospitalized patients with acute MI in 1981 and 1984. A variety of demographic (e.g. age, sex, teaching hospital) and clinical characteristics (e.g. MI order, MI type, MI location, peak CPK findings, occurrence of acute clinical complications) were also associated with the use of these therapies. The results of this community-wide study suggest changes over time in the therapeutic management of patients hospitalized with acute MI and of various patient demographic and clinical factors associated with the use of these agents.

Adrenergic beta-Antagonists↗
PubMed2003

Cholesterol: from heart attacks to Alzheimer's disease.

The accumulation and aggregation of the amyloid-beta peptide (Abeta) in the brain are important contributing factors to Alzheimer's disease (AD). Consequently, blocking the generation of Abeta is a potentially important treatment strategy. Recent work on the metabolism of Abeta has identified several cellular proteins and proteases that collectively promote or prevent the generation of Abeta. In addition, accumulating in vitro and in vivo evidence suggests a role for cholesterol in modulating the cellular processing of Abeta with the potential to affect AD.

Alzheimer Disease↗
PubMed1999

The helping process in couples during recovery from heart attack: a single case study.

This single case study aimed to illustrate help-intended communication in couples, in particular how a husband and wife attempted to help each other with adjusting to the husband's recent myocardial infarction. The study employed a semi-structured communication task to gather samples of the couple's helping interactions: the couple had two conversations in which they alternated helper and discloser roles. Quantitative and qualitative data were obtained from the couple and from expert raters (observers) about their perspectives of the conversations. The observers' ratings and verbal response mode patterns indicated that the conversations were characterized by low levels of empathy and exploration of feelings and relatively high levels of helper disclosure and advice; overall, the observers found the conversations to be somewhat unhelpful. In contrast, the couple rated the conversations more positively; the 'helpful events' they identified consisted of their partner disclosing a new piece of information and giving advice. The results were discussed in terms of the unique features of helping in close relationships.

Communication↗