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[High level Le Fort I osteotomy and bone grafting for correction of secondary mid-face deformities in cleft patients].

OBJECTIVE: To explore the feasibility of combining high level Le Fort I osteotomy with bone grafting in the same operation for correction of secondary mid-face deformities in cleft patients. METHODS: From January 2002 to January 2005, 10 patients suffering from secondary mid-face deformities were treated. There were 4 males and 6 females, aged from 16 to 32 years. The unilateral cleft was involved in 8 patients and the bilateral cleft in 2 patients. All patients received combining high level Le Fort I osteotomy with bone grafting in the same operation. The horizontal corticotomy of high level Le Fort I osteotomy on anterior wall of maxillary bone is higher than that of traditional Le Fort I osteotomy, it is only 5 mm close to infraorbital foramen. RESULTS: All 10 patients were satisfied with their appearances after operation. Dental articulation was improved greatly in 9 patients. With an X-ray re-examination, maxillary was returned to normal position in all patients. After a follow up from 6 months to 2 years, dental arch had good appearance. The X-ray films showed no obvious bone absorption. The density of grafting bone was approximation to the normal bone. CONCLUSION: High level Le Fort I osteotomy can make not only maxillary advance, but also regions of lateral and floor of nose and partial infraorbital region advance. Combining with bone grafting in the same operation can decrease the frequency of operation, save the treatment expense and obtain an ideal effect. So it is an effective method for correction of the secondary mid-face deformities in cleft patients.

Adolescent↗

Bisphosphonates: case report of nonsurgical periodontal therapy and osteochemonecrosis.

The risk of developing osteochemonecrosis is increased in patients who are taking bisphosphonate drugs and must undergo extractions or other dental surgery. Because of the difficulty in predicting and preventing osteochemonecrosis and in managing patients after it has occurred, avoidance of surgery has been advised. This paper reports on the development of this complication in a patient who received nonsurgical periodontal treatment. Although it is believed that the risk of developing this severely debilitating complication is low when treating patients nonsurgically, practitioners must be able to recognize and understand the presentation and difficulties in managing osteochemonecrosis, even when only nonsurgical therapy is performed.

Alveolar Bone Loss↗

Immediate provisional restoration of postextraction implants for maxillary single-tooth replacement.

The timing of implant placement and loading following tooth extraction has recently undergone substantial reconsideration. The authors tested a protocol of immediate loading of single implants placed at the time of tooth extraction in a consecutive case series. Thirty-three patients received a single implant-supported crown to replace a maxillary anterior tooth at the time of extraction. Regular recalls were planned for the following 4 years. One implant did not integrate, and another became unstable secondary to facial trauma. Overall patient satisfaction and clinical and radiographic parameters were good.

Adult↗

Using recombinant platelet-derived growth factor to facilitate wound healing.

Recombinant human platelet-derived growth factor (rhPDGF-BB) is a bioactive protein that has been combined with bone graft materials in an effort to regenerate the periodontium to its prediseased state more predictably. The combination of a biocompatible scaffold with this highly purified, recombinant human growth factor capitalizes on PDGF's stimulatory effects on cellular migration and proliferation, with subsequent matrix formation, to drive the healing process toward regeneration. When using a growth factor such as rhPDGF-BB with broad wound healing activity, an added clinical benefit is the more rapid soft tissue wound healing pattern observed at the surgical site. This also may be seen as a patient-centered benefit because it allows dentists to provide for a patient's prosthetic care on a timely basis, leading to a faster return to normal function. Also, the patient may resume plaque control efforts earlier, which further facilitates the wound-healing process. The purpose of these 2 case reports is to document the use of rhPDGF-BB as a wound-healing agent in 2 clinical situations and to provide a rationale for its use in this capacity.

Aged↗

[Alveolar cicatrix].

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Cicatrix↗

[[Studies of Ossification of the posterior longitudinal ligament in the cervical spine using microradiography and histochemistry (author's transl)].

ossification of the posterior longitudinal ligament (OPLL) is seen by X-ray as a condition which shows a heterotopically formed bony shadow at the posterior part of vertebral bodies of the cervical spine. OPLL causing severe myelopathy is called a Japanese disease. Recently, it has been shown that this condition is not only seen in Japan, but also in other countries especially in Asia. In order to obtain information of pathogenesis of this condition, the present author carried out histochemical investigations on 2 autopsy cases which had been treated as OPLL myelopathy, and 12 surgical materials. Totally 30 spinal vertebrae were examined. They were prepared for study with undemineralized ground sections mainly. The following results were obtained. 1) Microradiography revealed that the calcified tissue on the ligament had two marked structures, one was highly calcified tissue, and the other was bony tissue with lower density. 2) Most of the highly calcified tissue with variable distribution ranging from a sparse to a dense one contained round radiolucent spots probably consisting of cartilage-like cells. This type of calcified tissue is accompanied by the organic matrix, which was stainable with van Gieson stain, PAS reaction, Alcian blue stain and toluidin blue metachromasia. 3) A part of highly calcified tissue showed linearly distributed pattern without radiolucent round spots. This type of calcified tissue was also stained with van Gieson stain and PAS reaction. However, this organic matrix was not accompanied by marked reaction of acid mucopolysaccharides. 4) No essential histochemical difference was found between the highly calcified tissue on the ligament and other various types of heterotopically formed calcified tissue. 5) Microradiography revealed the remnant of resorption process at the boundary between the highly calcified tissue and the bony tissue. This finding of the resorption lacunae indicated that the highly calcified tissue was formed initially, followed by bone tissue formation. The process of internal remodeling was also observed in the bony tissue. 6) The distribution of the highly calcified tissue, bony tissue and resorption cavities indicated several patterns of remodeling process which was characterized by the new bone formation at the region near the vertebral body. These characteristics were apparently due to the mechanical stresses acting on this bony structures, as seen in some other heterotopic bone formations such as the healing process of fracture or tooth extraction socket.

Adult↗

Autogenous tooth transplantation: a reevaluation.

This paper discusses whether autogenous tooth transplantation can survive as an option in the future dental armamentaria. Clinically, successful transplants must show a radiolucent space between the roots and surrounding bone. There must be no evidence of ankylosis, no permanent root resorption, and no inflammation. Histologically, the criterion of success is a normal and functional periodontal ligament between the root surfaces of transplants and the bone or gingival connective tissues. Case reports are presented to illustrate replantation or transplantation of teeth. Possible donor teeth are those with the proper amount of viable periodontal ligament, single-rooted teeth, third molars, and malpositioned or impacted teeth. The transplantation procedure involves extraction of the donor tooth, measurement of the root form and amount of periodontal ligament, preservation of donor tooth, preparation of recipient socket, positioning of donor tooth, suturing, and temporary splinting.

Adolescent↗

[Immediate extractions-implantations].

Immediate implants are implants placed into a prepared extraction socket following tooth removal. Short-term animal and human studies have shown these implants to be comparable to implants placed into healed bone. The results in term of bone integration can be optimised by a better consideration of the surgical site. The evolution of the concept of the immediate placement of endosseous implants into extraction sites, along with the related concept of guided regeneration, is a major advancement in the surgical field. It provides significant benefit to both patient and clinician in terms of the reduced treatment time and an enhanced prognosis related to biomechanics and esthetics.

Alveolar Process↗

Clinical and microbiological aspects of the Sargon immediate load implant.

A maxillary lateral incisor with severe periodontal destruction was extracted after forced eruption and was replaced with a Sargon Immediate Load Implant. The clinical and microbiological results of the case are reported. The Sargon Immediate Load Implant is an apically expandable, quintapodal, root-form dental implant, designed to be loaded immediately with a provisional fixed restoration in normal occlusion.

Dental Implantation, Endosseous↗

Implant placement enhanced by bioactive glass particles of narrow size range.

Poor bone quality and quantity are often related to implant failure. Synthetic bone grafts may be used to enhance the formation of new bone in bone defects. The purpose of this animal study was to determine the efficacy of bioactive glass particles of narrow size range (300 to 335 microns, Biogran) in the treatment of bone defects prior to implant placement. On both sides of the mandible of six beagle dogs, areas of partial edentulousness were created by the removal of the intra-alveolar septa to obtain large defects, instantly filled on one side with bioactive glass particles. The other side was left empty as a control. After a healing period of 4 months, three oral implants each were placed in the glass-treated area and in the control zone. In three dogs, the implants were left subgingival for 3 months after which histologic sections were made. In the remaining three dogs, the implants were functionally loaded with a fixed partial prosthesis for 7 weeks before sacrifice. Qualitative and quantitative analysis of both groups revealed statistically significantly more bone tissue and higher remodeling activity at the interface and at a distance of implants placed in glass-treated areas, compared to implants placed in untreated regions. Implant placement in bioactive glass-filled defects was not jeopardized, on the contrary.

Alveolar Bone Loss↗

Preservation of the alveolar ridge at implant sites.

This case report describes an alternative surgical approach which can avoid the need for secondary regenerative techniques for ridge augmentation when planning treatment for dental implants. Our patient had a hopeless maxillary left central incisor, which was subsequently extracted in preparation for implant restoration. The site had a significant defect, which was treated at the time of extraction with a combination of a xenograft and a cortical chin graft. The goal was to preserve the residual ridge contour to avoid a compromise in implant fixture placement and maximize function and esthetics.

Aged↗