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Caretakers' perceptions of clinical manifestations of childhood malaria in holo-endemic rural communities in Tanzania.

A cross-sectional household survey was carried out in Kibaha district, Tanzania to obtain caretakers' knowledge on symptoms of childhood malaria in children under five years of age in relation to its management. A total of 1530 caretakers were interviewed, 620 (40.5%) reporting malaria attacks among their children in the last three months of which, 432 (70%) reported that the attacks were severe. Only 15.7% (68/432) of those reporting severe attacks could mention convulsions as symptoms of severe malaria, while fever and vomiting were mentioned as symptoms of severe malaria by 93.3% (403/432) and 52.3% (226/432) of the care-takers respectively. Higher level of education was significantly associated with knowledge of symptoms of severe malaria, also with promptness in taking management action. The fact that most of the caretakers reported fever and vomiting as symptoms of severe malaria, and hence the observed high proportion of reported severe malaria, implies that the communities under study do not perceive febrile convulsion as being a symptom of severe malaria. The implication of these findings on the control of malaria through treatment on demand are discussed.

Adult↗

Risk factors and spatial patterns of hookworm infection among schoolchildren in a rural area of western Côte d'Ivoire.

This study is aimed at investigating the risk factors for hookworm infection among schoolchildren in a rural area of western Côte d'Ivoire and predicting and mapping the spatial distribution of infection. We used demographic and socio-economic data from a cross-sectional survey of 6-16-year-old schoolchildren from 56 schools. Infection with hookworm was determined by microscopic examination of stool samples employing the Kato-Katz technique and an ether-concentration method. Environmental data were derived from satellite images and digitised maps. Bayesian variogram models were applied to investigate the variation of hookworm infection in relation to demographic, socio-economic and environmental factors. The overall hookworm infection prevalence, based on the pooled microscopic diagnoses, was 43.3% and ranged from 5.4 to 79.1% in the schools surveyed. Bivariate analyses showed that sex, age, socio-economic status, elevation, rainfall and land cover were significantly associated with the spatial distribution of hookworm infection. The final multivariate spatial model consisted of the covariates age, sex, socio-economic status, elevation and land cover. When assuming non-stationary underlying spatial dependency, the results of the model suggested that spatial correlation depended on the location only marginally. We conclude that, at the current resolution, it seems more reasonable to target interventions based on well-established epidemiologic risk factors, rather than on spatial factors.

Adolescent↗

[Urbanization in China. Data on the transformation of the urban system].

Recent trends in urbanization in China are analyzed. "This article presents new figures, as recently published in China, discusses their significance and draws some conclusions about the quality of modern urbanization in China. There are mainly three basic factors responsible for the present situation: 1. The tremendous increase in the rural population; 2. The influence of historical times from which two different city systems evolved (the traditional one and the colonial); 3. The planning strategies since 1949." The author notes that although the overall level of urbanization is low, there are considerable differences in regional urbanization levels. It is suggested that there have been profound changes in the Chinese urban system and urban spatial distribution patterns, which are not yet reflected in the available statistics. (SUMMARY IN ENG)

Asia↗

[Preliminary results on the residence distribution at birth of patients with Alzheimer's disease in the Saguenay-Lac-Saint-Jean/Quebec (the IMAGE project)].

The IMAGE Project is pursuing the establishment of a population-based registry of Alzheimer's disease (AD) cases in the Saguenay-Lac-Saint-Jean (SLSJ) (Quebec). The authors report on the spatial distribution at birth of 221 possible, probable and definite cases. A large network of key-informants for screening AD cases has been established over SLSJ. The spatial distribution of cases at birth and at the onset of disease has been computed by calculating the Alzheimer birth rate (ABR) on the basis of three scales: six specific geographical spheres of screening, all municipalities, and the public health departments. The statistical significance of results was determined using the theoretical Poisson and the Chi square distributions. ABR for each of the geographical spheres of screening showed no statistically significant differences considering either residence at the onset of the disease or residence at birth. Furthermore, differences were observed between rural and urban areas with an interesting trend for a higher number of cases than expected in one area of SLSJ. The spatial distribution of cases considered on the basis of residence at birth appears to show a different pattern, but no significant, from that measured on the basis of residence at the onset of disease. Screening of cases is actively being pursued all across SLSJ by the IMAGE network. There is a clear trend towards rural residence at birth of cases. It remains to see whether or not this observation is due to a geographical concentration of familial cases.

Alzheimer Disease↗

Survival of classic cholera in Bangladesh.

During the present cholera pandemic the El Tor biotype of Vibrio cholerae has completely displaced the classic biotype, except in Bangladesh. We studied the distribution of these two biotypes in twenty-four rural districts during epidemics in 1988-89; there was clustering of the classic biotype in the southern region and of the El Tor biotype in all other regions. These findings suggest that the southern coastal region is now (and may always have been) the habitat of classic cholera. The selective distribution of V cholerae O1 biotypes in Bangladesh may have been affected by ecological changes occurring in the country.

Bangladesh↗

The influence of a large city on some soil properties and metals content.

Urban soils differ from the rural ones by the fact that they are more strongly influenced by anthropogenic activities. This influence is often reflected by a high degree of contamination. To investigate the influence a large city can have on its soils and on the surrounding ones, samples within the city of Torino, Italy were compared with a set of surrounding soils developed from the same alluvial parent material. City-country trends were investigated by spatially managing the samples. Results show that the city plays a key role in concentrating some pollutants, such as Pb, Zn, and Cu within its borders. Lead is the element most enriched in the city, presenting a pollution index of 7.5 calculated comparing the two sets of samples. Ni and Cr appear to have a strong natural contribution. The spatial distributions for Pb, Cu and Zn present an abrupt division between urban and rural samples. Unexpectedly, the transport of pollutants from the city to the surrounding areas seems to be limited as no city-country trends with distance are identified. The pH and the sand fraction result also influenced by the city, showing high values. The investigation of possible city-country distance trends has shown to be effective in evaluating the impact a city can have on its soils and on the transport and deposition of contaminants on the surrounding ones.

Cities↗