Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Periapical Tissue”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 559 records · Page 31Linked to original sources
PubMed2006

Immunoelectron microscopic analysis of CD11c-positive dendritic cells in the periapical region of the periodontal ligament of rat molars.

To increase understanding of structural and phenotypic characteristics of dendritic cells (DCs) in the periapical region of the periodontal ligament (PDL) of rat molars, we performed immunoelectron microscopy for CD11c, a previously untested DC marker. Results demonstrated that CD11c clearly recognized DCs, although it also labeled certain macrophage subpopulation(s). In the normal PDL, resident DCs that extended several long cytoplasmic processes from their oval to slender cell body were identified. When the PDL was bacterially challenged by three days of unsealed pulp exposure, relatively small, irregularly shaped DCs with many thin and short cytoplasmic processes, most likely representing newly recruited DCs, were detected. The ratio of DCs in CD11c+ cells was significantly higher than that in ED1 (anti-macrophages and DCs)-positive and OX6 (anti-major histocompatibility complex class II molecules)-positive cells in normal and challenged PDL.

Animals↗
PubMed2004

Immediate loading of hydroxyapatite-coated implants in the maxillary premolar area: three-year results of a pilot study.

STATEMENT OF THE PROBLEM: Although immediate loading of implants in the edentulous mandible has been described in the literature, there is limited information regarding immediate loading of single implants. PURPOSE: This prospective clinical study evaluated the clinical parameters of immediately loaded single-threaded hydroxyapatite-coated (HA) root form implants. MATERIAL AND METHODS: Ten human subjects were included in this report. In all situations, a screw-retained provisional acrylic resin crown was placed in the maxillary premolar area immediately after implant surgery. Definitive screw-retained metal-ceramic prostheses were placed 6 months after surgery. Standardized periapical radiographs were made before implant surgery, immediately after surgery, and 1, 3, 6, 12, and 36 months after implant surgery. Mobility (measured with the Perio-Test), distance from implant platform to the gingival crevice, distance from the implant platform to the depth of the sulcus, peri-implant probing depth, and bleeding on probing index were recorded at 3, 6, 12, and 36 months after implant placement. For clinical measurements, a 5-mm healing abutment was placed. RESULTS: All implants appeared clinically osseointegrated. Standardized radiographs demonstrated mean marginal bone loss of 0.6, 0.7, 0.8, 0.9, and 1.0 mm at 1, 3, 6, 12, and 36 months after implant surgery, respectively. Mean implant mobility was -3.3 at the day of surgery and -3.8, -3.4, -3.6, and -4.2 at 3, 6, 12, and 36 months, respectively. The distance from implant platform to the gingival crevice was 2.8, 2.4, 2.4, and 3.1 mm at 3, 6, 12, and 36 months, respectively. The distance from the implant platform to the depth of the sulcus was 0.8, 0.9, 0.9, and 1.1 mm at 3, 6, 12, and 36 months, respectively. The peri-implant probing depth was 3.6, 3.3, 3.2, and 4.3 mm at 3, 6, 12, and 36 months, respectively. The bleeding on probing index was 0.4, 0.4, 0.4, and 0.1 at 3, 6, 12, and 36 months, respectively. CONCLUSION: The results of this prospective pilot study provide initial evidence that single root form implants may be immediately loaded when placed at the maxillary premolar area.

Adult↗
PubMed2006

Subjective image quality of digitally filtered radiographs acquired by the Dürr Vistascan system compared with conventional radiographs.

OBJECTIVES: To compare the different digital filters implemented in the Dürr Vistascan system with conventional film and to analyze the filter specificity to anatomic structures. STUDY DESIGN: Ten panoramic image pairs and 10 periapical image pairs (1 digital and 1 conventional) were obtained from 20 patients conventionally and digitally. The display quality of different anatomic image structures was rated subjectively on a 5-point scale. The responses were evaluated using ANOVA and Tukey-Kramer post hoc tests. The intraobserver reliability was evaluated by Cohen's kappa statistics. RESULTS: The display quality of anatomic structures was rated higher by using Caries 1 or 2 filters for periapical and Periodontal 1 or 2 filters for panoramic images, whereas nonfiltered and Noise Reduction-filtered images received the lowest scorings compared to all other digital image modalities (P < or = .0097). The superiority of conventional radiographs to the digital ones was statistically significant (P < or = .0039 and P < or = .0152 respectively). CONCLUSIONS: Depending on the diagnostic task, digital images of the Vistascan system should be filtered before examination. Perfect conventional radiographs still remain the gold standard for image quality.

Adult↗
PubMed2003

Intracellular localisation of SNARE proteins in rat parotid acinar cells: SNARE complexes on the apical plasma membrane.

Intracellular localisation of soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptors (SNAREs) is an important factor in clarifying whether SNAREs regulate exocytosis in salivary glands. We investigated intracellular localisation of syntaxins 2, 3 and 4 and SNAP-23, which are thought to be target membrane (t)-SNAREs, in rat parotid gland by Western blotting and immunocytochemistry. Syntaxins 2 and 3 were localised in the apical plasma membrane (APM), and syntaxin 4 was localised in the plasma membrane. SNAP-23 was localised in the APM and intracellular membrane (ICM). In a yeast two-hybrid assay, syntaxins 2, 3 and 4 interacted with SNAP-23 and VAMP-3. Using immunoprecipitation methods, syntaxins 3 and 4 were seen to interact with VAMP-8 and SNAP-23 at the APM, respectively. SNAP-23 interacted with syntaxin 3, syntaxin 4, VAMP-2, VAMP-3 and VAMP-8. Many SNARE complexes were detected under non-stimulated/basic conditions in the parotid APM. Some of these complexes may have a role in exocytosis from parotid acinar cells.

Animals↗
PubMed1998

Coexpression of vasoactive intestinal polypeptide and substance P in reinnervating pulpal nerves and in trigeminal ganglion neurones after axotomy of the inferior alveolar nerve in the rat.

The effect of this axotomy on the expression of vasoactive intestinal polypeptide (VIP) in trigeminal ganglion neurones and nerve fibres in the first molar was examined immunohistochemically 3 weeks postsurgically in rats. A distinct upregulation of VIP-like immunoreactivity was found in 3 to 4% of the neurones (mean dia., 20.9 +/- 0.45 microns; mean cross-sectional area, 367 +/- 13.2 microns 2) in the mandibular region after axotomy. An almost complete coexpression was registered in neurones upregulated for VIP and growth-associated protein 43. Coexpression of VIP and substance P (SP) was found in a small number of the immunoreactive (IR) small-sized neurones, mainly in those in which VIP and SP were both weakly immunoreactive. In the uninjured ganglion, weakly labelled VIP-positive granules were frequently traced at high magnification in the cytoplasm of small neurones. No VIP-IR fibres were found in the control molar pulp, except for a few in the root pulp near the apex. However, 3 weeks after axotomy, a number of VIP-containing nerve fibres were found in the molar pulp and apical periodontium. Coarse VIP-IR fibres directed towards the odontoblast layer were a common finding. In some of these fibres VIP was shown to colocalize with SP. These results indicate that VIP is clearly expressed and transported in regenerating primary afferent neurones after axotomy of the inferior alveolar nerve.

Animals↗
PubMed1972

Histiocytosis 'X'.

Explore the source record for details and available documents.

Eosinophilic Granuloma↗
PubMed1995

Histopathological observations of periapical repair in teeth with radiolucent areas submitted to two different methods of root canal treatment.

Dogs' teeth with induced chronic periapical periodontitis were treated endodontically by two different methods, and the results were compared. A total of 40 root canals from the upper and lower premolars of two dogs were prepared chemomechanically. In method 1, a high-concentration (5.25%) hypochlorite solution was used during the instrumentation of the root canal, and an antibacterial dressing was applied between sessions, followed by filling of the root canal. In method 2, a low-concentration (0.5%) sodium hypochlorite solution was used as an adjunct to mechanical debridement, and the root canal was filled during the same session. The histopathological results showed that method 1 led to better periapical repair than method 2.

Animals↗
PubMed1995

Effect of traumatic occlusion on periapical lesions in rats.

The effect of traumatic occlusion on periapical lesions in rats was investigated histologically and histometrically. Rats were divided equally into groups A to D. Rats in group A received no treatment; in group B, rats received pulpal exposure of the left mandibular first molar; in group C, a resin plate was cemented onto the occlusal surface of the corresponding maxillary molar; and in group D, the molar pulp was exposed and the resin plate was installed. At 1 and 2 wk, compression of the periodontal ligament and inflammation were less in group D than in group B. Lesions in the periapical periodontal ligament at 1, 2, and 4 wk in group D were significantly smaller than those in group B. This study suggests that traumatic occlusion delayed the enlargement of the periapical lesions in rats.

Alveolar Bone Loss↗
PubMed1993

Drying periapical films: simplified chairside technique.

A technique is presented for constructing a chairside radiograph dryer to be used after manual developing of films in the operatory. It is of simple construction using household items and common dental laboratory materials.

Humans↗
PubMed1995

Infiltrate of chronic lymphocytic leukemia appearing as a periapical radiolucent lesion.

This report presents a case of a mandibular premolar with a vital pulp and a periapical radiolucent lesion in a patient with a history of chronic lymphocytic leukemia. Biopsy of the lesion revealed an infiltrate of chronic lymphocytic leukemia in the mandible, which is quite rare. This lesion may have portended a worsening of the patient's condition and downgrading of her prognosis.

Aged↗
PubMed1990

Digital subtraction radiography for detecting cortical and cancellous bone changes in the periapical region.

Previous studies have found that bony lesions cannot be visualized on conventional radiographs unless there is cortical plate involvement. The aim of this project was to compare the sensitivity of digital subtraction to conventional radiography for detecting periapical changes in cortical and cancellous bone. Using a long source-to-object X-ray technique and E-speed film, serial radiographs of a dry skull mandible were obtained. Two bone lesions per radiograph were simulated using #1 to 8 round burs. Conventional and digitally subtracted images were evaluated for lesion presence by a board of reviewers. The results demonstrated greater sensitivity scores for digitally subtracted images in identifying cortical and cancellous bone changes. The lower limit of detection was less for digitally subtracted images in cortical and cancellous bone as well.

Alveolar Process↗