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Aesthetic correction of a contour deformity of the neck with buried expanded flaps.

This case report describes the use of two tissue expanders to correct a contour deformity of the neck, secondary to radical block dissection and radiotherapy for a recurrent parotid tumor. One flap was deepithelialized and then buried under the other to create the necessary bulk. This technique provided tissue similar in texture and color to the adjacent skin, and there is minimal donor site morbidity. It is, however, a staged procedure.

Adult↗

Multiple endocrine neoplasia type II.

The clinical characteristics, methods of diagnosis, and treatment of MEN-II have been described. Attention in the future should be focused on diagnosing MCT at the earliest possible time in MEN-II family members. The development of chemotherapeutic or other antitumor agents for the treatment of metastitic MCT should prove a fertile field for investigation.

Adrenal Gland Neoplasms↗

Magnetic resonance imaging of benign mediastinal masses.

Eight patients who had benign mediastinal masses underwent CT and magnetic resonance (MR) imaging. The intensity difference between mass and surrounding mediastinal fat was greater on MR than CT images. Although the masses were clearly identified with both modalities, delineation of a mass from surrounding mediastinal structures was better with CT. Heterogeneity on CT and MR images was a prominent feature of most larger benign mediastinal masses, although this should not be considered indicative of benignity. These benign mediastinal masses were best demonstrated on MR images obtained using a long TR and short TE. In general, the MR studies provided information comparable to but not identical to that of CT scanning. The viewing of mediastinal masses using a variety of TR and TE imaging parameters appeared to be an important aspect of the MR studies.

Adenoma↗

Radioguided surgical advancements for head and neck oncology.

Radioguided surgery is an innovative means by which a radionuclide is used to preoperatively image and intraoperatively visualize a structure of interest to the surgeon for excisional biopsy. This technology has allowed a cost-effective, highly specific means by which to locate a structure (usually a lymph node) and access it for pathologic analysis. The result of radioguided surgery is increased specificity in tissue obtained for biopsy, minimal access incisions, and the reduction of inpatient hospital utilization. Radioguided surgery should not be confused with radiosurgery, which is the stereotactic application of external beam radiation, usually for intracranial tumors.

Adenoma↗

[Incidence of medullary thyroid gland carcinoma in unilateral and bilateral pheochromocytoma].

In the autopsy material of the Departments of Pathology in Zürich and Winterthur the frequency of cases with unilateral or bilateral pheochromocytoma and combinations of pheochromocytoma with additional medullary thyroid carcinoma with amyloid has been studied. 56 cases (0.084 percent) of pheochromocytoma, 50 unilateral and 6 bilateral, were found in a material of 66782 autopsies. Three of the 6 patients with bilateral pheochromocytomas had an additional medullary thyroid carcinoma with amyloid deposits, while no patient with unilateral pheochromocytoma exhibited this type of thyroid tumor. In families with Sipple's syndrome, however, combinations of unilateral pheochromocytoma with medullary thyroid carcinoma do occur. No typical coincidence of pheochromocytoma with other malignant tumors could be demonstrated in our material, although this possibility is discussed in the literature.

Adolescent↗