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[Anorgasmic women].

The authors compare the results of a sexuological investigation in a group of 1266 gynaecological, married and sexually orgastic patients with a group of married gynaecological patients who during marriage did not experience orgasm during coitus. Statistically highly significant differences between the two groups were found in 18 factors. Based on an analysis of these differences the authors express the view that sexual dysfunction in the sense of "inhibited female orgasm" has a multifactorial background, whereby biological as well as psychological factors are involved.

Adult↗

Sexual function and testosterone levels in men with nonalcoholic liver disease.

The effects of nonalcoholic liver disease on sexual desire, arousal, activity, orgasmic function and satisfaction and serum testosterone levels were studied in 75 men with nonalcoholic liver disease. Each man was interviewed about his sexual behavior and problems and was asked to comment on whether he felt liver disease affected his sexual function. The average age of the patients was 49 yr, and a wide variety of liver diseases was represented. Child-Pugh grading was A in 51 patients, B in 18 and C in 6; the mean duration of liver disease was 8 yr. Sexual desire, arousal and activity of patients with grade A disease were within the ranges observed in studies of healthy men of comparable age. Diminished sexual desire was reported by 2% of grade A patients and 35% of grade B and C patients (p less than 0.005). Arousal problems were noted by 16% of grade A patients, 60% of grade B patients and 67% of C patients (p less than 0.005). Loss of erection and inability to regain erection were noted by 7%, 40% and 67% of grade A, B and C patients, respectively (p less than 0.01). Premature and retarded ejaculation were more frequent in patients classed in Child-Pugh grades B and C. Frequency of coitus and orgasm were significantly higher in grade A patients than in grade B and C patients. Total and free testosterone levels were (in nanograms per milliliter) A, 677/1.78; B, 416/1.06; and C, 178/0.43 (p less than 0.002). We concluded that Child-Pugh grade A nonalcoholic liver disease in men does not affect sexual desire, function or performance. Men with disease grades B and C have significant sexual dysfunction and significant reduction of both total and free testosterone levels.

Adult↗

[Sexual dysfunction in men following surgical treatment for rectosigmoid carcinoma].

In a retrospective study we performed an analysis of the sexual (dys)function in 26 men operated in the University Hospital Leiden, the Netherlands, for rectosigmoid carcinoma. Nine patients (mean age 59.8 years (45-67)) underwent abdomino-perineal resection and 17 (mean age 59.5 years (43-75)) underwent (low) anterior resection. All men were sexually active before surgery. Following abdomino-perineal resection only 2 patients are sexually active, five are unable to achieve an erection and seven have no orgasms. Three patients only achieve an incomplete erection. One patient has a retrograde ejaculation. Following anterior resection 12 of 17 patients are sexually active, four are unable to achieve an erection or orgasm. Four patients only achieve an incomplete erection. Five patients have a retrograde ejaculation. It is concluded that sexual disorders occur frequently after surgery for rectosigmoid carcinoma, and following abdomino-perineal resection in practically all cases, while the nature of the disorder varies greatly. It is very important to inform the patient before surgery.

Aged↗

The circumvaginal musculature: correlation between pressure and physical assessment.

This study assessed two recently developed techniques to assess the circumvaginal musculature (CVM), the CVM Rating Scale and the pressure sensitive intravaginal balloon device (IVBD), and correlated results of the two methods. Thirty women volunteers, aged 20 to 42, were studied. CVM Rating Scale total scores and IVBD maximal contraction variables were measured for resting pressure, rate of rise, maximal pressure, rate of return, and time that a submaximal contraction could be sustained (endurance contraction). Age, parity, self-reported orgasm, self-reported Kegel exercises, and self-reported physical exercise were separately correlated with CVM Rating Scale total scores and IVBD maximal pressure results. A positive significant correlation was found between the CVM Rating Scale total scores and the IVBD maximal contraction results for the variables rate of rise, r = .50, p less than .01, maximum pressure, r = .82, p less than .01, and rate of return, r = .44, p less than .01. Self-reported orgasm had a positive significant correlation to the CVM Rating Scale total scores, rho = .34, p less than .05, and to the IVBD maximal pressure results, r = .52, p less than .01. A positive correlation was found between self-reported physical exercise and the CVM Rating Scale total scores, rho = .31, p less than .05. IBVD maximal pressure results were negatively correlated with age, r = -.34, p less than .05, and parity, r = -.34, p less than .05.

Adult↗

[Headache related to sexual intercourse (author's transl)].

Coïtal cephalalgic (CC) is rare (1/360 headaches); it occurs more frequently among men. Out of 16 unpublished cases, in 4 cases, CC was the inaugural symptom of vascular attack. In the 12 other cases, CC was isolated or primary. According to the time of onset of headache during coït one may distinguish three types: 1) early CC usually moderate and short lasting; 2) orgasmic CC, abrupt, severe, lasting 15 to 20 minutes; 3) late CC of long duration (hours, days) follows sometimes orgasmic CC. Isolated CC is usually repetitive but capricious, episodical, not periodical. Prognosis is good. Mechanism is mainly vascular and muscular. The role of high blood pressure, migraine, and psychological factors is discussed.

Coitus↗

Human vaginal pH and sexual arousal.

The surface pH of the vagina was measured before and after sexual arousal by self-stimulation in ten healthy women. The mean value of six spots measured and pH measured in collected vaginal fluid was highly correlated. Two-way analysis of variance showed a mean increase of pH after orgasm (significant at the 0.5% level). The Wilcoxon matched-pairs test and a paired t-test showed a significant increase in three and four of the subjects, respectively, and a decrease in pH in one other subject. It is concluded that in the present laboratory setting, clitoral self-stimulation to orgasm only results in small changes of the vaginal surface pH.

Adult↗

Anorgasmia associated with imipramine but not desipramine: case report.

A case of imipramine-induced orgasmic inhibition in a woman is reported. Desipramine, the metabolite of imipramine, did not produce this reaction. The ability of imipramine to block the CNS neuronal reuptake of serotonin (a property not shared by desipramine) is considered the probable pathophysiologic mechanism in the failure to achieve orgasm.

Desipramine↗

Sexuality and pregnancy. A prospective study.

The normative changes in various sexual variables in pregnancy remain controversial. Much of the data available have been derived from retrospective and subjective, prospective investigations. The present prospective study indicated decreases in sexual enjoyment, coital frequency and orgasm as pregnancy progressed. A midtrimester increase in sexual desire preceding a progressive decrease was evident. Overall sexual satisfaction was correlated with feeling happy about being pregnant, feeling more attractive in late pregnancy than before pregnancy and experiencing orgasm. Anticipatory guidance and informed counsel regarding sexual changes in pregnancy should be provided to help pregnant patients and their husbands adapt to the pregnancy and enhance their marital bonds.

Adolescent↗

Dreams and dreaming in relation to trauma in childhood.

The aim of this paper is to show how some childhood fantasies which were part of the early traumas or of traumatic dreams may continue to dominate the psychic life of the adult and be revealed in the transference neurosis. A trauma is presented as an experience which becomes a prototype not only of that which is most frightening but also of that which is sexually most stimulating and gratifying. It is thus doubly invested in a contradictory way. Extensive clinical material is described to show that many of a woman patient's transference fantasies, produced and recounted during her session, were similar to those which had been part of a childhood traumatic dream. A link is established between these same fantasies and her principal symptoms. In particular it is pointed out that her most disturbing symptom, an inability to have an orgasm, was rooted in the fact that she continued to believe that an orgasm was a trauma, i.e. the most intensely desired yet most terrifying experience in which the anticipated consequences, as depicted symbolically in her dream, were simultaneous ecstasy and castration. The traumatic childhood dream exerted an irresistible fascination on the patient who felt it still controlled her in mysterious and unconscious ways. In essence the dream dramatized unforgettably her relations to her oedipal objects and became the model for what she was repetitively seeking, yet dreading, with later substitutes. It is shown how the dream, which became a remembered trauma, served as a point of fixation upon which her drives were focused and around which her fantasies revolved.

Adolescent↗

[Cerebral dysfunction and disorders of sexual behaviour (author's transl)].

The effects of epilepsy and focal brain lesions on sexual behaviour are described. Fits may be provoked by hypervenilation in epileptics during sexual activity, but also by orgasm and other sexual stimuli. Epileptic auras consisting of tactile genital sensations and sexual feelings, including orgasm, also occur. Post-ictal sexual automatisms consist of masturbation or other poorly structured activity, imitating the gestures of sexual intercourse. Focal brain lesions most commonly produce a reduction in sexual activity. However, frontal lobe lesions may produce disinhibition with inappropriate sexual behaviour and temporal lobe lesions may be associated with true hypersexuality, transvestite and transsexual behaviour. Eleven cases, which illustrate the various associations, are described.

Adolescent↗

[Anejaculation: its etiology and pathogenesis, classification and clinical aspects].

43 patients suffering from anejaculation were treated in 1983-1993 in the department of andrology of the N. A. Semashko Medical Institute urological clinic. Most commonly anejaculation is caused by prostatic and bladder neck surgery (25.6%), diabetes mellitus (18.6%) and presents as retrograde ejaculation, impaired sperm emission into the urethra, aspermatism (51.2, 27.9, 20.9% of patients, respectively). The leading pathogenetic factors are peripheral neuropathy, surgical injury to the bladder internal sphincter, psychosexual disorders. The authors propose classification and algorithm of the patients' examination to facilitate and enhance diagnosis. Special attention should be given to the presence or absence of orgasm, after-orgasm occurrence of spermatozoa in urine. Anejaculation treatment outcomes remain unsatisfactory. Good responses were achieved with selective adrenomimetic gutron, laser therapy and electrovibration. Prevention of anejaculation should be given more attention.

Adolescent↗

A double-blind crossover trial of clomipramine for rapid ejaculation in 15 couples.

BACKGROUND: The purpose of this study was to assess the sexual and psychosocial efficacy of clomipramine for rapid ejaculation. METHODS: Fifteen physically healthy, self-selected couples (men had a mean age of 38 years) who met six eligibility criteria and did not meet five exclusion criteria participated in a variable-length, repeated measures, randomized, double-blind, placebo-controlled crossover study with a 2-month follow-up period. Sexual and psychosocial assessments were conducted at baseline, after placebo, after 25 mg/day of clomipramine, after 50 mg/day of clomipramine, and at the 2-month follow-up point. The major outcome measures included stopwatch timing of ejaculation latencies, modified Case Western Reserve University Sexual Function Questionnaire, Symptom Checklist-90-R, Dyadic Adjustment Scale, State-Trait Anxiety Inventory, and the Harder Self-Esteem Inventory. RESULTS: Baseline mean ejaculatory latency was 81 seconds; 25 mg/day of clomipramine increased it to 202 seconds and 50 mg/day of clomipramine to 419 seconds. This resulted in significantly greater sexual satisfaction scores for men and their partners (men, p < .001; women, p < .05), improvements in partner coital orgasmic attainment, and greater relationship and emotional satisfaction for the men. Withdrawal of the drug caused ejaculatory latencies to return to baseline. CONCLUSION: Clomipramine appears to be effective in significantly lengthening ejaculatory latencies and increasing sexual and relationship satisfaction. It can be a cost-effective chronic therapy for selected patients. These impressive results should not be expected in a less carefully screened population of men concerned about the timing of their orgasm during intercourse.

Adult↗

Sexual dysfunction in male schizophrenic patients.

BACKGROUND: Neuroleptic treatment in schizophrenic patients is associated with sexual dysfunction. However, it is not clear to what extent the psychiatric disorder and/or the pharmacologic treatment are responsible for the sexual impairment. The aim of the present study was to evaluate the sexual function of untreated and treated male schizophrenic patients in comparison with healthy subjects. METHOD: Participants included 122 male subjects: 20 drug-free schizophrenic patients, 51 neuroleptic-treated (depot form) schizophrenic patients, and 51 normal controls. A detailed structured interview was used to quantitatively and qualitatively assess sexual function. RESULTS: A high frequency of sexual dysfunction was reported by both schizophrenic groups of patients. Impairments in arousal items (erection) and orgasm during sex were reported mainly by the treated patients. Desire parameters were reduced in both schizophrenic groups, but reduction in the frequency of sexual thoughts was confined to the untreated one. The schizophrenic patients were more involved in masturbatory activity in comparison with the control subjects. Treated patients disclosed dissatisfaction with their sexual function. CONCLUSION: Untreated schizophrenic patients exhibit decreased sexual desire. Neuroleptic treatment is associated with restoration of sexual desire yet it entails erectile, orgasmic, and sexual satisfaction problems. Clinicians' awareness and open discussion of sexual problems with patients may improve comprehension and compliance.

Adult↗

Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum.

BACKGROUND: We performed a study to assess sexual and urinary function after total mesorectal excision with autonomic nerve preservation for primary carcinoma of the rectum. STUDY DESIGN: We studied retrospectively postoperative sexual and urinary function in 136 (78 percent) of 175 eligible patients (82 males and 54 females) who responded to a standardized questionnaire. RESULTS: The ability to engage in intercourse was maintained by 86 percent of the patients younger than 60 years of age, and by 67 percent of patients 60 years and older. Eighty-seven percent of male patients maintained their ability to achieve orgasm. The type of surgery (abdominoperineal resection compared to low anterior resection), and age equal to or greater than 60 years were significantly associated with male sexual dysfunction. Of the female patients, 85 percent were able to experience arousal with vaginal lubrication and 91 percent could achieve orgasm. The majority of patients had few or no complaints related to urinary function. Serious urinary dysfunction such as neurogenic bladder was not encountered. CONCLUSIONS: Autonomic nerve preservation in association with total mesorectal excision reduces the operative morbidity rate and is successful in minimizing sexual and urinary dysfunction in the operative treatment of patients with carcinoma of the rectum.

Adult↗

Offspring sex ratio in women with android body fat distribution.

The relationship between waist-to-hip ratio (WHR), several behavioral factors, and the number of male and female offspring was examined in a sample of 69 women. Two questions were examined: (1) Are hormonal differences, as indicated by differences in the WHR, associated with offspring sex ratio? and (2) are there any behavioral factors, such as coital frequency or orgasm, that are associated with offspring sex ratio? After statistically controlling for subject's age, socioeconomic status, and total number of offspring, we found that women with a higher WHR tended to have more sons than daughters. In addition, women who reported greater ease of having multiple orgasms also tended to have more sons than daughters. The results thus support both a hormonal and a behavioral influence on offspring sex ratio.

Adult↗

[Sexual changes in men with urological disorders].

OBJECTIVE: To evaluate the changes in sexual function due to urological pathologies and their treatment in the male. The present study analyzed erection, ejaculation, frequency of sexual intercourse and orgasm. METHODS: A questionnaire comprised of 30 items were sent out to 1016 males over 18 years of age with urological disease that had been treated from 1990 to 1991. Data processing was carried out using the Statgraphics and Statistica programs. The x2 and Wilcoxon Z tests were utilized for statistical analysis. RESULTS: All of the parameters studied were found to be impaired in a high number of patients in relation to age, pathology and treatment. Benign prostatic hyperplasia and its treatment caused the most impairment. CONCLUSIONS: Erection, ejaculation, frequency of sexual intercourse and orgasm decreased significantly after a urological condition. In our view, patient preoperative data and analysis of the foregoing parameters are warranted.

Adult↗

Group treatment format: mixed sexual dysfunctions.

This study reports the rationale and results of a ten-session group composed os six couples with mixed sexual dysfunctions. Dysfunctions included premature ejaculation, primary and situational orgasmic dysfunction, situational impotence, and incompatible sex drives. A variety of pretreatment behavioral and attitudinal measures were administered, including a Life History Questionaire, Sexual Assessment Inventory, Marital Adjustment Scale, and Sexual Interaction, orgasmic attainment, ejaculatory control, and enhanced self-acceptance, particularly for females (SII changes). The consistency between outcome measures was also a noteworthy finding. The results suggest increased use of mixed short-term groups, particularly when cost-effectiveness accountability is important. One contraindication for such groups is, however, severe marital discord, as evidenced by Locke-Wallace mean scores of 80 or less.

Adaptation, Psychological↗