Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Library Surveys”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 559 records · Page 31Linked to original sources

Mobilization of duplicates in a Regional Medical Library Program.

An overabundance of duplicate journals without an efficient and economical method of distribution caused one library's staff to reassess traditional methods of dispersal. A simplified form for listing duplicates was devised. In conjunction with the Regional Medical Library Program and the extension program, lists of duplicates were distributed to hospital and clinical libraries. These libraries selected materials to strengthen their ability to fill information needs at the local level and to conserve RMLP support for esoteric and expensive materials. In a two-year period, 86,000 individual pieces were distributed. Some lessening of interlibrary loan requests from heavy users was documented. In an evaluation survey users expressed satisfaction with the program. The successful use of the duplicate program will lead to a further experiment--the library will attempt to fill interlibrary loan requests for common journals with hard copy rather than photocopy in a cost and time reduction effort.

Book Collecting↗

Synthetic statistical approach reveals a high degree of richness of microbial eukaryotes in an anoxic water column.

Molecular surveys suggest that communities of microbial eukaryotes are remarkably rich, because even large clone libraries seem to capture only a minority of species. This provides a qualitative picture of protistan richness but does not measure its real extent either locally or globally. Statistical analysis can estimate a community's richness, but the specific methods used to date are not always well grounded in statistical theory. Here we study a large protistan molecular survey from an anoxic water column in the Cariaco Basin (Caribbean Sea). We group individual 18S rRNA gene sequences into operational taxonomic units (OTUs) using different cutoff values for sequence similarity (99 to 50%) and systematically apply parametric models and nonparametric estimators to the OTU frequency data to estimate the total protistan diversity. The parametric models provided statistically sound estimates of protistan richness, with biologically meaningful standard errors, maximal data usage, and extensive model diagnostics and were preferable to the available nonparametric tools. Our clone library exceeded 700 clones but still covered only a minority of species and less than half of the larger protistan clades. Our estimates of total protistan richness portray the target community as very rich at all OTU levels, with hundreds of different populations apparently co-occurring in the small (3-liter) volume of our sample, as well as dozens of clades of the highest taxonomic order. These estimates are among the first for microbial eukaryotes that are obtained using state-of-the-art statistical methods and can serve as benchmark numbers for the local diversity of protists.

Anaerobiosis↗

[The libraries of the public hospitals in Spain. An economic analysis. The Research Group on Libraries].

BACKGROUND: The continuous increase in scientific knowledge in the health field, the development of new technologies and the rising cost of publications means that libraries are essential for patient care, medical education and research. In Spain some deficiencies have been seen in hospital libraries, and their cost is unknown. OBJECTIVE: To analyze the cost of public hospital libraries in Spain and to estimate the cost of adapting them to international standards. METHODS: Cross-sectional survey of public hospitals larger than 100 beds, or smaller public hospitals with teaching accreditation. Information on the variables of interest was collected by questionnaire mailed to the libraries and followed up by telephone. Data collection was completed in 1996. The information on costs is for 1994. A sensitivity analysis was done to examine the effects of imprecise estimates and assumptions. RESULTS: Of the 314 hospitals identified, 211 (67.2%) had libraries. The 1994 cost of the of the 211 libraries was 3,060 million pesetas (mean cost: 14.5 million pesetas). Personnel costs were the most important item (38% of the total), followed by the cost of subscriptions (29%). The cost of hospital libraries represented 0.08% of national public expenditures on health. The cost of correcting inadequacies in accordance with international standards would increase spending by about 400 million pesetas the first year (0.01% of public spending on health). CONCLUSIONS: The cost of hospital libraries represents only a small fraction of public spending on health. Correction of the observed deficiencies and the importance of libraries in the health system would require increasing spending to about 0.1% of public spending on health.

Costs and Cost Analysis↗

Microbial diversity of cryptoendolithic communities from the McMurdo Dry Valleys, Antarctica.

In the McMurdo Dry Valleys of Antarctica, microorganisms colonize the pore spaces of exposed rocks and are thereby protected from the desiccating environmental conditions on the surface. These cryptoendolithic communities have received attention in microscopy and culture-based studies but have not been examined by molecular approaches. We surveyed the microbial biodiversity of selected cryptoendolithic communities by analyzing clone libraries of rRNA genes amplified from environmental DNA. Over 1,100 individual clones from two types of cryptoendolithic communities, cyanobacterium dominated and lichen dominated, were analyzed. Clones fell into 51 relatedness groups (phylotypes) with > or =98% rRNA sequence identity (46 bacterial and 5 eucaryal). No representatives of Archaea were detected. No phylotypes were shared between the two classes of endolithic communities studied. Clone libraries based on both types of communities were dominated by a relatively small number of phylotypes that, because of their relative abundance, presumably represent the main primary producers in these communities. In the lichen-dominated community, three rRNA sequences, from a fungus, a green alga, and a chloroplast, of the types known to be associated with lichens, accounted for over 70% of the clones. This high abundance confirms the dominance of lichens in this community. In contrast, analysis of the supposedly cyanobacterium-dominated community indicated, in addition to cyanobacteria, at least two unsuspected organisms that, because of their abundance, may play important roles in the community. These included a member of the alpha subdivision of the Proteobacteria that potentially is capable of aerobic anoxygenic photosynthesis and a distant relative of Deinococcus that defines, along with other Deinococcus-related sequences from Antarctica, a new clade within the Thermus-Deinococcus bacterial phylogenetic division.

Alphaproteobacteria↗

Hospital outpatient surgery cost, reimbursement, and utilization data find Medicare a loser.

Data Library: Outpatient surgery costs, reimbursement, and utilization benchmarks. This new CHIPS survey finds providers consistently lose money for 56 outpatient procedures under Medicare. The only winners are those in high managed care areas and high-volume facilities. The data offer some valuable benchmarks by geographic area, managed care penetration, as well as age and sex.

Ambulatory Surgical Procedures↗

[Post-delivery care after episiotomy].

OBJECTIVES: Attempt to define the most appropriate care after an episiotomy, the best-suited treatments of the pain of episiotomy, and examine the course of repair stitches. MATERIAL AND METHODS: A survey of the literature found on Medline and on the Cochrane Library between 1990 and 2005, and dealing with these questions was carried out. RESULTS: As regards local care, the best possible personal hygiene is a key to healing, but no specific treatment has been accepted. The treatment of pain by non-medical means as well as topically is not very efficient. Nonsteroidal antiinflammatory drugs were the most studied among medical treatments and have shown an effect on pain (whether per os or by rectal route), some of them can be used during maternal breastfeeding. Acetaminophen has not been sufficiently studied to assess its effectiveness. CONCLUSION: The medical staff must emphasize the importance of self care and personal hygiene. The pain of episiotomy is a crucial element to treat, and it is most effectively done medically. The treatment must be adapted to each patient depending on her tolerance and whether she is breastfeeding or not.

Adult↗

Prospective studies of the safety of acupuncture: a systematic review.

PURPOSE: The objective of this review was to determine the incidence of adverse events associated with acupuncture. SUBJECTS AND METHODS: A search for prospective surveys of the safety of acupuncture was conducted using computerized databases (Medline, Embase, the Cochrane Library, and CISCOM), inquiries to acupuncture organizations, and our own files. Data on sample, size, types of patients duration of study, types of acupuncture, definition of adverse events, method of evaluation, and findings were extracted systematically from the retrieved reports. RESULTS: Nine surveys were located and included in the review. Their results were not uniform. The most common adverse events were needle pain (1% to 45%) from treatments, tiredness (2% to 41%), and bleeding (0.03% to 38%). Feelings of faintness and syncope were uncommon, with an incidence of 0% to 0.3%. Feelings of relaxation were reported by as many as 86% of patients. Pneumothorax was rare, occurring only twice in nearly a quarter of a million treatments. CONCLUSIONS: Although the incidence of minor adverse events associated with acupuncture may be considerable, serious adverse events are rare. Those responsible for establishing competence in acupuncture should consider how to reduce these risks.

Acupuncture Therapy↗

Annotating the human proteome: the Human Proteome Survey Database (HumanPSD) and an in-depth target database for G protein-coupled receptors (GPCR-PD) from Incyte Genomics.

The Proteome Division of Incyte Genomics has released new volumes to the BioKnowledge Library to add human, mouse and rat protein information to its rich collection of model organism Proteome Databases. The Human Proteome Survey Database (HumanPSD) compiles the fundamental properties of more than 25 000 characterized mammalian proteins. HumanPSD includes clear, concise and current protein descriptions (Title Lines), the protein sequence, calculated physical properties, precomputed BLAST alignments, controlled-vocabulary protein properties and Gene Ontology terms, and a list of published references. Each report also contains expression data, Pfam domain information and an associated Mouse Mutant Phenotype section describing behavioral, physiological and cellular phenotypes for over 1500 mouse mutant phenotypes. GPCR-PD contains more than 3200 Protein Reports from the three mammalian species for G protein-coupled receptors, their protein ligands, associated G-proteins and their downstream signaling proteins. In addition to the features described above, each GPCR-PD Protein Report displays annotations of experimental findings from over 10 000 publications. These databases provide important new volumes of Proteome's BioKnowledge Library (http://www.incyte.com), integrating protein information from model organisms with the human proteome.

Amino Acid Sequence↗

An evaluation of information-seeking behaviors of general pediatricians.

OBJECTIVE: Usage of computer resources at the point of care has a positive effect on physician decision making. Pediatricians' information-seeking behaviors are not well characterized. The goal of this study was to characterize quantitatively the information-seeking behaviors of general pediatricians and specifically compare their use of computers, including digital libraries, before and after an educational intervention. METHODS: General pediatric residents and faculty at a US Midwest children's hospital participated. A control (year 1) versus intervention group (year 2) research design was implemented. Eligible pediatrician pools overlapped, such that some participated first in the control group and later as part of the intervention. The intervention group received a 10-minute individual training session and handout on how to use a pediatric digital library to answer professional questions. A general medical digital library was also available. Pediatricians in both the control and the intervention groups were surveyed using the critical incident technique during 2 6-month time periods. Both groups were telephoned for 1- to 2-minute interviews and were asked, "What pediatric question(s) did you have that you needed additional information to answer?" The main outcome measures were the differences between the proportion of pediatricians who use computers and digital libraries and a comparison of the number of times that pediatricians use these resources before and after intervention. RESULTS: A total of 58 pediatricians were eligible, and 52 participated (89.6%). Participant demographics between control (N = 41; 89.1%) and intervention (N = 31; 70.4%) were not statistically different. Twenty pediatricians were in both groups. Pediatricians were slightly less likely to pursue answers after the intervention (94.7% vs 89.2%); the primary reason cited for both groups was a lack of time. The pediatricians were as successful in finding answers in each group (95.7% vs 92.7%), but the intervention group took significantly less time (8.3 minutes vs 19.6 minutes). After the intervention, pediatricians used computers and digital libraries more to answer their questions and spent less time using them. CONCLUSION: This study showed higher rates of physician questions pursued and answered and higher rates of computer use at baseline and after intervention compared with previous studies. Pediatricians who seek answers at the point of care therefore should begin to shift their information-seeking behaviors toward computer resources, as they are as effective but more time-efficient.

Computer User Training↗

General practitioners' use of evidence databases.

OBJECTIVE: To determine the awareness and use of the Cochrane Library and access to the Internet by general practitioners in New South Wales. DESIGN: Cross-sectional postal survey in September 1997. PARTICIPANTS: 311 of 428 (73% response rate) randomly selected general practitioners in New South Wales. MAIN OUTCOME MEASURES: Proportion of respondents with access to the Internet at home or at work; proportion of respondents aware of, with access to, and ever using the Cochrane Library; independent predictors of awareness of the Cochrane Library. RESULTS: 134 respondents (43%) had access to the Internet either at home or at work; 42 (14%) were "on line" at their workplace. Seventy (22%) were aware of the Cochrane Library, although only 20 (6%) had access to it and 13 (4%) had ever used it. Those in group practice and members of Divisions were independently more likely to be aware of the Cochrane Library. CONCLUSIONS: As patient outcomes will improve with systematic implementation of evidence-based treatments, these low rates of access to useful evidence databases raise issues regarding the best ways to support general practitioners with information technology.

Adult↗

Library instruction within the medical record administration curriculum.

A course for medical record administration (MRA) students has been developed at the University of Tennessee Center for the Health Sciences Library. The course's objectives are: (1) to train students in the use of the resources and services of health sciences libraries and (2) to provide basic instruction in the organization, operation, and management of a small hospital library. These objectives are met by integrating library use instruction within the MRA curriculum and by presenting a five-week hospital library management workshop. Library use instruction includes a library orientation and sessions on the use of major reference sources, writing for publication, and the use and evaluation of the medical record literature. The workshop covers the role of the medical record administrator as manager of the hospital library. Sessions cover basic principles of hospital library administration, technical and public services, and sources of outside assistance. Results are reported of a survey of graduates conducted to determine whether a need for the course still existed and if the changes made as a result of the evaluation process were appropriate. The teaching methods and evaluation techniques used in this course are applicable to library instruction in other disciplines.

Hospitals↗

Chiropractic student attitudes toward radiology.

INTRODUCTION: Diagnostic radiology is an important component of chiropractic education. Because ineffective teaching is costly in time and resources, educators need to continually evaluate both the content and design of their radiology curriculum. METHODS: A survey was administered to 121 senior students from one chiropractic institution immediately after completing presentation of the last of 11 radiology topics presented. Students reported their interest and perceived understanding of radiology topics and indicated which resources they thought were almost helpful during their training. RESULTS: Students ranked arthritides as the most interesting radiology subject and patient positioning as least interesting. They felt more time should be devoted to arthritides and case correlation/patient management issues, with less time devoted to radiology physics and patient positioning. Students felt that they best understood patient positioning, skeletal trauma, arthritides and bone tumors. They reported having less understanding of specialized imaging physics. Of those learning methods available, class lectures and film review sessions were the most helpful radiology resources; film teaching libraries and videodisc system were the least helpful. CONCLUSION: The results of this survey suggest more emphasis needs to be placed on radiology subjects that focus on the application of imaging studies in patient management and on correlating imaging findings to clinical circumstances. It seems that less time should be devoted to patient positioning and radiographic physics. Results of this survey need to be compared with goals of the radiology curriculum and objective testing before appropriate modifications are implemented.

Adult↗

Genomic organization and expression analyses of putrescine pathway genes in soybean.

Putrescine is synthesized using one of two alternative pathways in plants, from arginine by arginine decarboxylase (ADC) or from ornithine by ornithine decarboxylase (ODC) and is catabolized by diamine oxidase (DAO). A survey of approximately 310,000 expressed sequenced tags (ESTs) in soybean EST libraries identified diverse representation of ADC, ODC, and DAO ESTs, with ODC being least frequent and DAO ESTs most abundant. Southern analysis suggested that ADC and ODC belong to small gene families, and DAO is the most divergent. Using three bacterial artificial chromosome (BAC) libraries, 26X genome equivalents, two common loci for ADC and DAO and one independent DAO locus were identified. ADC and DAO are physically linked in the soybean genome within approximately 150 kb. Identification of genomic regions encoding ODC proved difficult and required using additional BAC libraries, increasing genome coverage to approximately 40X. Using Real Time reverse transcriptase-polymerase chain reaction (RT-PCR), higher steady-state levels of ADC than ODC in roots, leaves, shoot apices, and dry seeds suggested that ADC is the predominant pathway for putrescine biosynthesis in soybean. However, organ-specific expression showed that root is the major site of ODC transcription. Significantly elevated accumulation of ADC mRNA and elevated putrescine content in seeds of the fasciation mutant compared with the wild type may stimulate cell divisions and establishment of enlarged apical meristem during early mutant ontogeny. The DAO frequent representation in EST libraries constructed from root tissue and elevated steady-state levels in roots compared to above ground tissues show DAO is critical for regulation of putrescine content in soybean roots.

Amine Oxidase (Copper-Containing)↗

A structurally biased combinatorial approach for discovering new anti-picornaviral compounds.

BACKGROUND: Picornaviruses comprise a family of small, non-enveloped RNA viruses. A common feature amongst many picornaviruses is a hydrophobic pocket in the core of VP1, one of the viral capsid proteins. The pocket is normally occupied by a mixture of unidentified, fatty acid-like moieties, which can be competed out by a family of capsid-binding, antiviral compounds. Many members of the Picornaviridae family are pathogenic to both humans and livestock, yet no adequate therapeutics exist despite over a decade's worth of research in the field. To address this challenge, we developed a strategy for rapid identification of capsid-binding anti-picornaviral ligands. The approach we took involved synthesizing structurally biased combinatorial libraries that had been targeted to the VP1 pocket of poliovirus and rhinovirus. The libraries are screened for candidate ligands with a high throughput mass spectrometry assay. RESULTS: Using the mass spectrometry assay, we were able to identify eight compounds from a targeted library of 75 compounds. The antiviral activity of these candidates was assessed by (i) measuring the effect on the kinetics of viral uncoating and (ii) the protective effect of each drug in traditional cell-based assays. All eight of the candidates exhibited antiviral activity, but three of them were particularly effective against poliovirus and rhinovirus. CONCLUSIONS: The results illustrate the utility of combining structure-based design with combinatorial chemistry. The success of our approach suggests that assessment of small, targeted libraries, which query specific chemical properties, may be the best strategy for surveying all of chemical space for ideal anti-picornaviral compounds.

Animals↗

A controlled vocabulary for nursing and allied health in Norway.

Nursing and allied health libraries at educational institutions in Norway have generally indexed their book collections with uncontrolled terms. With the reorganization of higher education in 1994, the majority of these libraries joined BIBSYS, which is a joint library system for higher education and research in Norway. This has led to chaos when searching the joint catalogue for literature on nursing and related fields. A term such as 'behaviour problems' may have up to five synonyms. In an attempt to improve the quality of searching the health literature, BIBSYS appointed a working group in the Spring of 1999 to find a suitable controlled vocabulary for this subject area, and to see how this vocabulary could be integrated into BIBSYS. The group presented its recommendations in October 1999. The report has been well received by the BIBSYS Board and by user groups. There are no Norwegian vocabularies that are suitable for use in nursing and allied health, therefore it will be necessary to translate and combine existing thesauri. The group has looked at the Nordic Multilingual Thesaurus on Health Promotion, the Swedish Spriline Thesaurus, MeSH (Medical Subject Headings) and CINAHL Subject Heading List. Other relevant thesauri are AMED/CATS Thesaurus, Bioethics Thesaurus (Bioethicsline) and the RCN thesaurus. The group recommends the development of a Norwegian thesaurus based on a translation of parts of MeSH and CINAHL Subject Heading List.

Abstracting and Indexing↗

Policy and procedural guidelines for the health and safety of workers in virus laboratories.

Through the use of a (a) a questionnaire, designed to elicit background information, (b) a serological survey, designed to obtain a picture of virus dissemination, and (c) a library review, designed to gain insight into the area of virus laboratory problems, the state of hazard in animal virus laboratories at Yale was evaluated. On the basis of this evaluation, a series of recommended guidelines for protecting the health and safety of workers in those laboratories was formulated.

Animals↗

Reducing obesity and related chronic disease risk in children and youth: a synthesis of evidence with 'best practice' recommendations.

Childhood obesity is a global epidemic and rising trends in overweight and obesity are apparent in both developed and developing countries. Available estimates for the period between the 1980s and 1990s show the prevalence of overweight and obesity in children increased by a magnitude of two to five times in developed countries (e.g. from 11% to over 30% in boys in Canada), and up to almost four times in developing countries (e.g. from 4% to 14% in Brazil). The goal of this synthesis research study was to develop best practice recommendations based on a systematic approach to finding, selecting and critically appraising programmes addressing prevention and treatment of childhood obesity and related risk of chronic diseases. An international panel of experts in areas of relevance to obesity provided guidance for the study. This synthesis research encompassed a comprehensive search of medical/academic and grey literature and the Internet covering the years 1982-2003. The appraisal approach developed to identify best practice was unique, in that it considered not only methodological rigour, but also population health, immigrant health and programme development/evaluation perspectives in the assessment. Scores were generated based on pre-determined criteria with programmes scoring in the top tertile of the scoring range in any one of the four appraisal categories included for further examination. The synthesis process included identification of gaps and an analysis and summary of programme development and programme effectiveness to enable conclusions to be drawn and recommendations to be made. The results from the library database searches (13,158 hits), the Internet search and key informant surveys were reduced to a review of 982 reports of which 500 were selected for critical appraisal. In total 158 articles, representing 147 programmes, were included for further analysis. The majority of reports were included based on high appraisal scores in programme development and evaluation with limited numbers eligible based on scores in other categories of appraisal. While no single programme emerged as a model of best practice, synthesis of included programmes provided rich information on elements that represent innovative rather than best practice under particular circumstances that are dynamic (changing according to population subgroups, age, ethnicity, setting, leadership, etc.). Thus the findings of this synthesis review identifies areas for action, opportunities for programme development and research priorities to inform the development of best practice recommendations that will reduce obesity and chronic disease risk in children and youth. A lack of programming to address the particular needs of subgroups of children and youth emerged in this review. Although immigrants new to developed countries may be more vulnerable to the obesogenic environment, no programmes were identified that specifically targeted their potentially specialized needs (e.g. different food supply in a new country). Children 0-6 years of age and males represented other population subgroups where obesity prevention programmes and evidence of effectiveness were limited. These gaps are of concern because (i) the pre-school years may be a critical period for obesity prevention as indicated by the association of the adiposity rebound and obesity in later years; and (ii) although the growing prevalence of obesity affects males and females equally; males may be more vulnerable to associated health risks such as cardiovascular disease. Other gaps in knowledge identified during synthesis include a limited number of interventions in home and community settings and a lack of upstream population-based interventions. The shortage of programmes in community and home settings limits our understanding of the effectiveness of interventions in these environments, while the lack of upstream investment indicates an opportunity to develop more upstream and population-focused interventions to balance and extend the current emphasis on individual-based programmes. The evidence reviewed indicates that current programmes lead to short-term improvements in outcomes relating to obesity and chronic disease prevention with no adverse effects noted. This supports the continuation and further development of programmes currently directed at children and youth, as further evidence for best practice accumulates. In this synthesis, schools were found to be a critical setting for programming where health status indicators, such as body composition, chronic disease risk factors and fitness, can all be positively impacted. Engagement in physical activity emerged as a critical intervention in obesity prevention and reduction programmes. While many programmes in the review had the potential to integrate chronic disease prevention, few did; therefore efforts could be directed towards better integration of chronic disease prevention programmes to minimize duplication and optimize resources. Programmes require sustained long-term resources to facilitate comprehensive evaluation that will ascertain if long-term impact such as sustained normal weight is maintained. Furthermore, involving stakeholders in programme design, implementation and evaluation could be crucial to the success of interventions, helping to ensure that needs are met. A number of methodological issues related to the assessment of obesity intervention and prevention programmes were identified and offer insight into how research protocols can be enhanced to strengthen evidence for obesity interventions. Further research is required to understand the merits of the various forms in which interventions (singly and in combination) are delivered and in which circumstances they are effective. There is a critical need for the development of consistent indicators to ensure that comparisons of programme outcomes can be made to better inform best practice.

Body Mass Index↗