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Results for “GENERAL ADAPTATION SYNDROME”

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At least 559 records · Page 31Linked to original sources
PubMed1994

The stress response in critical illness.

Under normal, unstressed conditions, the body maintains a dynamic equilibrium known as homeostasis--a complex interplay balancing the conflicting demands presented by many internal and external forces. In the face of threatened or actual disruptions (i.e., stress), molecular, cellular, physiologic, and behavioral responses act to restore homeostasis. These responses can be specific to a particular stressor and relatively circumscribed (e.g., secretion of insulin in response to an increase in blood glucose), or can be generalized and relatively nonspecific (e.g., behavioral manifestations of severe anxiety). Typically, more nonspecific and generalized responses occur in the setting of severe and threatening disruptions in homeostasis, and taken together, these responses are known as the "general adaptation or stress syndrome". We will describe the elements and organization of the generalized stress response with particular attention to the hypothalamic-pituitary-adrenal axis as it interacts with the immune system, and we will review what is known about this interactive network in the setting of critical illness.

Animals↗
PubMedDate not supplied

[The current concepts of the adaptation of the human body to hyperbarism and its readaptation after decompression].

The data presented in the recent literature and the authors' results allow formulating basic positions of the conception on the phase adaptation to the increased density of gas mixtures (nitrogen, helium) with complete saturation. Each of the three phases is shown to depend on the intensity of hyperbaric stress and the organism state. A hypothesis is advanced that formation of the system functional and then a structural trace in possible in response to the repeated influences of prolonged hyperbarism. Cross deadaptation and decompensation of the systems which endure the highest functional load under hyperbarism are shown to be possible. A general syndrome of high pressures which unite nerve, respiratory, circulatory and metabolic components is characterized. Phases of the readaptation period are determined. Changes in main systems depending on periods after decompression are described.

Adaptation, Physiological↗
PubMedDate not supplied

[Emerging aspects of occupational stress].

Work stress is caused by excessive demands which foster individuals to give prompt cognitive and behavioral answers. When these solicitations exceed the possibilities of the subject to comply, non-physiological reactions may follow, including emotional, neurovegetative and behavioral changes. If adverse stimuli persist, transient alterations form syndromes such as depression, phobic syndromes, anxiety syndromes, hypertension, heart disease, eating disorders, drug addiction, and so on. The authors examine specific stressful working areas causing illnesses in workers such as the burnout syndrome and the mobbing-related adjustment disorder or the post-traumatic stress disorder.

Burnout, Professional↗
PubMedDate not supplied

[Biological effects of the action of a high-tension DC electrical field].

The experiments were carried out on 345 white mice using hematological and pathomorphological procedures. The constant electric field (CEF) was generated in a special laboratory device. The exposure to CEF of 50 and 100 kV/m for 20 s caused hematological and morphological changes typical of the anxiety stage of the adaptation syndrome. The exposure also produced morphological changes of reactive and destructive type in skeletal muscles and different segments of kinesthetic receptors. The level of the above changes appears to be directly related to the CEF strength.

Animals↗