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At least 559 records · Page 31Linked to original sources
PubMed2006

[Imaging strategy for staging and follow-up of endocrine tumors].

Endocrine tumours constitute a homogeneous network of tumours scattered in the body and characterized by several common features including their capacity to secrete hormones, their association as part of inherited syndrome and their ability to be explored either by functioning imaging than by morphological imaging. However, they have a broad and initially misleading clinical spectrum. Staging of these tumours must be multidisciplinary with the association of primary tumour exploration, staging and follow-up. It also contribute to the screening of complications due to hormonal secretions, the exploration of inherited syndromes and a second cancer diagnosis. First we review the technical characteristics of each imaging modality including morphological imaging (computed tomography, magnetic resonance imaging), metabolic imaging (somatostatin receptors scintigraphy, PET-scan), endoscopy and vascular imaging. Then we review for each endocrine tumour localization and clinical presentation, the imaging strategy as well as the most common morphological and functional features.

Bronchial Neoplasms↗
PubMed1991

[An appendicular villous adenoma].

Villous adenomas of the vermiform appendix are uncommon. Their malignant potential is unknown and their treatment is controversial. Because of a reported association between adenomas of the appendix and other gastrointestinal neoplasms, long-term surveillance is recommended. A new case of appendicular villous adenoma is reported.

Adenoma↗
PubMed1991

[Oncologic surgery/pathologic-anatomic viewpoint].

Important progress achieved during the last years in four fields is reported: (1) Preoperative histological diagnosis: use of immunohistology, improvements by the 2nd edition of the WHO International Histological Classification of Tumors; (2) pathology of lymphatic spread: detailed classification according to topography and number of involved nodes, increased knowledge of factors influencing lymphatic spread and standardization of examination methods with statements on the number of examined and involved nodes; (3) publication and worldwide acceptance of the uniform 4th edition of the TNM Classification; and (4) introduction of the residual tumor (R) classification.

Breast Neoplasms↗
PubMed1991

[Biochemical criteria of early diagnosis of postoperative pancreatitis in oncologic patients].

With the aim of diagnosis of postoperative pancreatitis in 88 oncologic patients operated on for malignant tumors of the upper alimentary canal and pancreatoduodenal zone, including those with trauma or resection of the pancreas, the comparative analysis of significance of different biochemical indices was carried out. A high sensitivity and informative value of measuring a content of the middle molecular mass peptides and components of kallikrein-kinin system with calculation of a toxicity coefficient permit to recommend their use as the additional diagnostic criteria.

Alanine Transaminase↗
PubMed1991

[Cerebral metastases in adenocarcinoma of the colon].

Between 25% and 35% of all patients with cancer, will develop metastases to the brain. Gastrointestinal neoplasms are responsible for 8% of all cases of metastatic brain involvement. The frequency of brain metastases in carcinoma of the colon ranges from 0.3 to 6%, and this location is usually accompanied by metastatic involvement of the lung and liver. Cerebral metastatic lesions are uncommon in colon cancer, and are usually a late manifestation of the disease. Because of the rarity of this complication, we report a case of metastatic colon adenocarcinoma to the brain, and we review the literature on this subject.

Adenocarcinoma↗
PubMed1977

A study of filling defects in the liver and spleen with multiple radionuclides.

Studies were made to determine if examination with multiple radiopharmaceuticals would improve the sensitivity and specificity of colloid liver spleen scans. Increased uptake of Ga-67 citrate and In-111 bleomycin was found in most Tc-99m sulfur colloid scan defects caused by hepatocellular hepatoma or lymphoma. Increased uptake of these agents was found in some defects caused by malignant melanoma, breast carcinoma and carcinoma of the lung, and was rarely seen in defects caused by cholangiocarcinoma or gastrointestinal neoplasms. Gallium was useful in the followup of patients with hepatoma. Procedures designed to evaluate the gall bladder fossa, renal impression, or blood pool activity of an apparent tumor were found to be helpful and simple to perform. Iodine-131 as NaI was useful in studying functioning liver metastases from thyroid carcinoma as were bone scanning agents in evaluating hepatic metastases from osteogenic sarcoma. Multiple radiopharmaceutical evaluation of the physiologic and biochemical characteristics of liver lesions supplements current radiologic examinations and increases diagnostic specificity.

Adenoma, Bile Duct↗
PubMed1990

Lymphoma of the hollow abdominal viscera.

Autopsy evidence of gross or microscopic GI involvement can be found in up to 51% of all lymphoma cases. In descending order of frequency the stomach, small intestine, colorectum, and esophagus may be involved. Radiologically, GI lymphomas tend to have similar morphologic characteristics regardless of their site of origin. Additionally, the diverse radiologic manifestations may mimic a variety of diseases. Nevertheless, growing clinical experience and improvements in imaging techniques have increased the frequency with which the proper diagnosis can be suggested. The extramucosal origin of a mass or masses is often detectable by double-contrast examination and dictates a diagnostic spectrum fundamentally different from that of tumors arising from the mucous membrane. Similarly, the ability of CT to determine the wall thickness of the involved segment and its relationships to adjacent structures has further increased radiologic specificity. These capabilities are important, not only from the diagnostic standpoint, but also with respect to staging, prognosis, and, ultimately, increased survival.

Esophageal Neoplasms↗
PubMed1990

[Intraoperative abdominal echography].

Results of the use of abdominal intraoperative echography are reported for the first time in this country. The diagnostic precision, the scanning technique and the problems encountered in examining 56 patients are discussed. The high value of the method in small hepatic tumors, hepatic cysts and abscesses, common bile duct calculosis and pancreas cancer is pointed out. In operative interventions on gastrointestinal neoplasms intraoperative echography may be used for continuing surgical palpation into the butt. To master the method and introduce it as a routine method in clinical practice it is necessary, to use modern equipment, to be skilled in scanning technique and to have thorough knowledge on the characteristics of the intraoperative images of the different pathologic processes.

Abdomen↗
PubMed1989

[Tumor markers used in oncology].

The most useful markers, include human chorionic gonadotropin (hCG), alpha-feto protein (AFP), and carcinoembryonic antigen (CEA). The major utility of those would be in monitoring patients with choriocarcinoma, the germ cell tumors, and gastrointestinal neoplasm. Tumors Markers have not been so successful in the early detection of neoplasm in the general population. Possible explanation will be the lack of specificity for tumors as opposed to normal tissue. Monoclonal antibodies to human tumors cell can be prepared using hybridization techniques. These antibodies are homogenoous, recognize specific antigenic determinants with high affinities, and can be mass produced. Monoclonal antibodies detect qualitative and quantitative differences in the antigenic composition of normal and malignant cells. Have important clinical application in the detection and early diagnosis of cancer, in accurate tumor staging, and in therapy.

Biomarkers, Tumor↗
PubMed1989

[Nontraditional fractionation of doses of ionizing radiation in clinical practice].

Various types of non-routine dose fractionation were used in 2062 patients with malignant tumors of different sites. The conclusion was that superfractionation was more preferable for tumors with a high proliferative pool, with fast growth rates, marked radiosensitivity. It ensures the protection of normal tissues without a decrease or even with an increase in an antitumor effect. Such fractionation can be recommended when large tissue areas are to be irradiated. Dynamic dose fractionation regimens proved to be more effective than the use of large fractions not only in squamous cell carcinoma but also in sarcoma both before operation and as therapy after a radical program.

Carcinoma, Non-Small-Cell Lung↗
PubMed1989

[Computed tomography of the esophagus, the stomach and the duodenum. Review of methods and results].

Computed tomography (CT) of the esophagus, the stomach and the duodenum allows characterization of some lesions: lipomas, cysts and duplications, recent haematomas, vascular anomalies. CT is particularly used for the extramural staging of neoplasms: despite important limitations, CT may be useful as staging test to identify a subgroup of patients with definitive metastases or local invasion who therefore have unresectable tumors. CT is helpful for the staging of lymphomas. The importance of this staging classification is reflected in differences in treatment and prognosis. CT is also useful for the follow-up after treatment, the diagnosis of recurrence and postoperative complications.

Esophageal Neoplasms↗