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PubMed1981

Pathological fractures through non-ossifying fibromas. Review of the Mayo Clinic experience.

Twenty-three cases of a pathological fracture through a lesion verified histologically as non-ossifying fibroma were seen over a forty-nine-year period. The average age of the patients at the time of fracture was twelve years. All fractures except one were located in the lower extremity, most frequently in the distal end of the tibia (ten). The percentage of bone occupied by the fibroma in the transverse plane exceeded 50 per cent on both the anteroposterior and the lateral radiographs in every patient. The vertical length was always the maximum dimension and in all non-fibular lesions exceeded thirty-three millimeters. Treatment consisted of cast immobilization with biopsy at a later date, simple curettage, curettage and autogenous bone-grafting, or segmental resection of fibular lesions.

Adolescent↗
PubMed1980

[Vaginal fibromas (author's transl)].

The author describes the characteristics of vaginal fibromas, as observed in one personal case and after a rview of the published literature. These tumors, which affect women during the period of genital activity, are not of frequent occurrence, and the principal signs are dyspareunia and metrorrhagia. The histological appearance of the tumours is very similar to that of uterine fibromas, but their pathogenicity appears to be different, and they progress in a similar manner to that of benign tumors. Because of the existence of a cleavage line they can be easily enucleated, the main therapeutic problem being the choice of the surgical approach to be employed.

Adult↗
PubMed1995

[A case of pulmonary fibroma].

A 42-year-old man without symptoms was admitted to the hospital because of a well-circumscribed mass in his left upper lung field, which was found on a routine chest X-ray film. CT of the chest revealed a well-defined homogeneous mass in the left upper lobe. Bronchial biopsy yielded material unsatisfactory for diagnosis. On thoracotomy a tumor, entirely within the lung parenchyma, was found to occupy S3. Due to its size and location left upper lobectomy was done. Histologically, the tumor contained interlacing bundles of spindle cells compatible with fibroma, with no indicators of malignancy. Intrapulmonary fibromas are rare and only one report could be found in the Japanese literature.

Adult↗
PubMed1995

[Fibrous dysplasia and ossifying fibroma. 2 unusual fibro-osseous lesions of the paranasal sinuses].

Fibrous dysplasia and ossifying fibroma are locally destructive and deforming benign lesions that can occur anywhere in the craniofacial skeleton, including the paranasal sinuses. Differentiation between these two diseases is essential because of their differing natural histories, and distinctions must be made by correlating clinical information with radiological and histological findings. The cases of fibrous dysplasia and ossifying fibroma described in this report illustrate the subtle differences between these two fibroosseous lesions. Emphasis is placed on the differing natural history and management of these two unusual lesions in order to expedite aggressive treatment when required.

Bone Cysts, Aneurysmal↗
PubMed1995

Nuchal fibroma. A clinicopathological study of nine cases.

Nuchal fibroma apparently was first described in the second edition of Enzinger's and Weiss's text book in 1988. We have been unable to find any other accounts of this entity. We have reviewed the clinicopathological features of nine nuchal fibromas, eight of which were referred in consultation. Eight patients were men; the ages ranged from 19 to 53 years (median, 43). Patients were first seen with solitary, unencapsulated, subcutaneous swellings in the back of the neck or dorsal region measuring from 2.5 to 8 cm in maximum dimensions (median, 3.5). Macroscopically, lesions were firm, fibrofatty masses. Histologically, there were sheets of hypocellular dense collagen with interspersed mature fat, inconspicuous, small, thin-walled vessels, and entrapped nerve fibers. The picture suggested a fibrolipoma, a lipomatosis, scar tissue, or even elastofibroma, but the small amount of elastic tissue present lacked the beaded, nodular appearance of elastofibroma. Follow-up information was available in seven cases. In follow-up times from 6 months to 19 years (median, 6 years), one tumor was reexcised 4 months after an incisional biopsy and had not recurred 19 months later. None of the others recurred. The lack of a capsule, the entrapment of nerves, and the predilection for the nuchal or dorsal regions suggest that this hypocellular, benign, fibrofatty lesion is a distinct entity and not merely a lipoma.

Adipose Tissue↗
PubMed1994

Cardiac fibroma: clinicopathologic correlates and surgical treatment.

The clinicopathologic findings of 23 patients with cardiac fibroma are presented. The mean patient age was 13 years, with a range of 1 day to 56 years. The presenting symptoms included heart failure, arrhythmias, sudden death, cyanosis, and chest pain. Some patients had no symptoms, and one patient had Gorlin's syndrome. Echocardiography and magnetic resonance imaging were very sensitive in diagnosis. Nineteen patients underwent tumor resection or biopsy, and four tumors were diagnosed at cardiac transplantation or autopsy on explanted hearts. In five surgical cases, complex operations were necessary, including pericardial or synthetic patches, valve replacement, or coronary artery grafting. Two operative deaths occurred in patients with surgical resections and four operative deaths in patients who at the time of the operation were deemed to have inoperable disease and only biopsy was performed. All deaths but one were in patients younger than 2 years of age. Four patients with subtotal resections did well after the operation. Dense collagen was more frequent in tumors in older patients. We conclude that fibromas are congenital tumors that are frequently discovered in adolescents and adults. Surgical treatment is generally successful, and imaging techniques are helpful in preoperative assessment.

Adolescent↗
PubMedDate not supplied

Fine needle aspiration cytology of chondroblastoma and chondromyxoid fibroma. A report of two cases.

The fine needle aspiration cytology in two cases of chondroblastoma and chondromyxoid fibroma are described. The diagnosis of chondroblastoma was made on a recurrent tumor of which the histopathology was known, whereas chondromyxoid fibroma was diagnosed initially on fine needle aspiration cytology. The radiologic appearances and differential diagnoses of these chondroid neoplasms are discussed.

Adolescent↗
PubMed1993

Ossifying cementicular fibroma of the orbitofrontal bone in a child: case report.

A rare case of ossifying cementicular fibroma of the left orbitofrontal bone that developed in a 12-year-old boy is presented. A hard, painless mass that was incidentally noticed gradually enlarged over 2 years. Skull X-rays showed a well-demarcated lesion with mixed sclerotic and osteolytic radiolucent changes in the left orbitofrontal bone. Computed tomography revealed an expansile intradiploic multilocular mass that was separated by bony trabeculae. T1-weighted magnetic resonance imaging demonstrated a multi-cystic iso-intense mass with homogeneous contrast enhancement. Left external carotid angiograms revealed a vague tumor stain that was mainly fed by the middle meningeal artery. Systemic bone scintigrams revealed a single abnormal uptake in the lesion. The skull tumor was totally removed. Histological examination demonstrated two different characteristic findings that were composed of fibrous dysplasia and cementifying fibroma, although most of the tumor appeared to be a highly cementicular form of fibro-osseous lesion. The pathological diagnosis was a cementicular variant of fibrous dysplasia.

Child↗
PubMed1995

Ovarian fibroma. A report of three cases.

The authors report three cases of ovarian fibroma in women in advanced menopause (mean age: 70 years). The neoplasm was bilateral in one patient. Early symptoms were pelvic pain, and, in one patient, menorrhagia without histologic alterations of the atrophic endometrium. The histology was typical of ovarian fibromas, except for one case which was characterized by a dense pseudofibrosarcomatous pattern and by the presence of numerous sex cord elements.

Aged↗
PubMed1995

Cellular fibroma of the ovary with Meigs' syndrome and elevated CA-125. A case report.

BACKGROUND: Cellular fibroma of the ovary is an uncommon benign tumor. When associated with Meigs' syndrome, it can produce a clinical picture similar to that of ovarian carcinoma. CASE: A 73-year-old nulligravida was admitted to the hospital with progressive cachexia, ascites, a right pleural effusion and a 15-cm pelvic mass. The serum CA-125 level was 1,780. Due to a high suspicion of ovarian carcinoma, the patient underwent exploratory laparotomy, total abdominal hysterectomy/bilateral salpingooophorectomy and surgical staging for a frozen section diagnosis of sarcoma. Permanent histology revealed the tumor to be a cellular fibroma, and the CA-125 levels fell to normal postoperatively. CONCLUSION: Since benign ovarian tumors may mimic carcinoma, laparotomy and appropriate surgical staging are essential for the final diagnosis.

Aged↗
PubMedDate not supplied

Ossifying fibroma. A case report.

Ossifying fibroma is a benign tumor of connective tissue origin which occurs in fibro-osseous lesions. The lesion is seen most commonly in children and young adults. It is asymptomatic and slow-growing, but in some cases may show aggressive behavior. Though it has a slight predilection for the mandible, it may involve both jaws. The lesion is generally asymptomatic until it produces noticeable swelling, and mild deformity and migrations of teeth may be an early clinical feature. Pediatricians and dentists must be aware when asymmetry of the face occurs, and the lesion must be well diagnosed as it has a cancer-like radiographic appearance. In this article a nine-year-old patient with a massive mandibular ossifying fibroma is presented.

Child↗
PubMed1995

[Clinico-pathological study on giant cell fibroma of oral mucosa].

The biopsy specimens of the Department of Oral Pathology, Dental School, UMBC, between 1985-1988 were reviewed in 1990 and. 124 cases of giant cell fibroma (GCF) of oral mucosa were found. GCF may develop at any age, but the highest incidence is middle adult life. GCF is slightly common in female than in male (1: 0.85). GCF occurs frequently in gingiva, tongue and cheek and is mistaken commonly for irritation fibroma, neurofibroma, papilloma and pyogenic granuloma, because there are no specific clinic features of it. The fusiform cells, star cells and multinucleated giant cells in the lesion are common histologic features of GCF. Local removal is usually successful.

Adolescent↗
PubMed1996

Massive right ventricular fibroma treated with partial resection and a cavopulmonary shunt.

Cardiac fibromas in infants and children may present as intramural or intracavitary masses. Total or partial resection as well as transplantation have been reported as treatment for symptomatic patients. We report an infant, diagnosed prenatally, who underwent partial excision of a massive obstructive right ventricular fibroma and creation of a bidirectional cavopulmonary shunt. The palliative approach has allowed the child to be followed up with the option of transplantation should the tumor continue to increase in size.

Female↗
PubMed1997

Cardiac fibroma presenting as sudden death in a six-month-old infant.

Cardiac fibroma is a rare benign tumour which occurs predominantly in infancy and childhood. We present the case of a six-month-old female infant who died suddenly at home and was found at autopsy to have a large cardiac fibroma in the ventricular septum. The tumour was apparently asymptomatic although there was evidence of mild cardiac failure. Death was thought to be due to a fatal arrhythmia.

Death, Sudden, Cardiac↗
PubMed1997

[Psammomamatoid ossifying fibroma of the frontal sinus with intracranial extension].

Case report of a 29-year-old woman with an psammomatoid ossifying fibroma of the left frontal sinus. Headache was the presenting clinical symptom. The tumor and its intracranial extension were identified by computed tomography and magnetic resonance tomography. Through a two-step combined neuro-rhinosurgical operation the tumor could be completely removed. Ossifying fibroma is a benign tumor mostly affecting the mandible and maxilla. A more aggressive approach may be more beneficial than expectant observation or curettage in the initial management of this benign neoplasm. Because of the unusual location of this rare entity the case history is published and differential diagnostic and therapeutical implications are discussed.

Adult↗
PubMed1998

Molluscum contagiosum in a soft fibroma: a particular combined lesion.

A case of a single molluscum contagiosum occurring on the surface of a preexisting soft fibroma in an adult patient is reported. The most common clinical form of this viral lesion is multiple grouping papules with a central umbilication and its histologic feature is characteristic. Previous cases of mollusca combining with other lesions have been rarely described. Our lesion was probably due to its localization on the soft fibroma, whose exophytic growing represented a favoring factor for trauma and the consequent occurrence of the viral disease.

Adult↗
PubMedDate not supplied

Calcified retroperitoneal fibroma.

A case of 31-year-old male with a retroperitoneal tumor is described. Abdominal ultrasound revealed a left para-aortic calcific mass, adjacent to the left lobe of the liver and to the upper pole of the left kidney. A CT-scan of the abdomen showed the mass to originate from the left adrenal gland. At operation, a large, retroperitoneal mass, adherent to the left kidney and the spleen, but not infiltrating, was excised. Histologically the tumor was diagnosed as a calcified osteo-producing fibroma. Benign retroperitoneal tumors represent about 25% of all retroperitoneal neoplasm. This reported case represents a retroperitoneal tumor of slow growth and benign clinical course whose characteristic consists of the heavy calcifications which are normally absent in a fibroma type mass.

Adult↗
PubMed1989

Chondromyxoid fibroma of the mastoid invading the occipital bone.

We describe a case of chondromyxoid fibroma of the mastoid bone extending along the occipital bone in a 48-year-old man. The presence of this tumor was heralded solely by aural fullness caused by otitis media with effusion. The tumor arose from the mastoid cavity, eroding the entire petrous portion, and invading the foramen magnum and jugular foramen. The occurrence of this tumor is exceedingly rare, and, to our knowledge, this is only the second article in the literature that describes a chondromyxoid fibroma of the mastoid region. The clinical appearance of this tumor and its light- and electron-microscopic findings are presented with reference to other articles.

Chondroma↗