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Testing the goodness-of-fit of a multifaceted preventive intervention for children at risk for conduct disorder.

OBJECTIVE: To determine the importance of parents' global adaptive functioning as a predictor of participation rate and subsequent child social competence outcome in 3 program components of an evidence-based, multifaceted, preventive intervention for at-risk children. METHOD: Families of program children (n = 124, mean age 6.6 years at recruitment) were offered 3 program components that continued for 3 years: a 6-week summer program, a biweekly family program that included concurrent parent and child education and skills training groups, and a flexibly tailored home visitation family support program. We used structural equation modelling to test hypotheses about the effects of parental characteristics on program attendance in each of the program components over 3 years, as well as their relation to children's social competence. RESULTS: Predictors of attendance included child IQ, socioeconomic status (SES), and single-parent status for some components but not others, depending on parents' global adaptive functioning. Predictors of child social competence outcome were mediated by attendance in specific program components and were dependent on parent global adaptive functioning. Some components contributed decisively to social competence outcomes, and others did not, despite subjects' participation. CONCLUSIONS: Common family characteristics (that is, child IQ, SES, and single-parent status) predict program attendance differently, depending on parents' global adaptive functioning. Parents' global adaptive functioning determined whether attendance in specific program components mediated children's social competence. In this preventive intervention, as in clinical practice, only knowledge of the goodness-of-fit between participant characteristics and program attributes can ensure optimum benefit.

Adaptation, Psychological↗

Psychopathology as a predictor of adolescent drug use trajectories.

The authors examined early psychopathology as a predictor of trajectories of drug use from ages 13-18 years. Six years of annual data were analyzed for 506 boys using a mixed effects polynomial growth curve model. They tested whether distinct measures of psychopathology and behavioral problems (i.e., attention-deficit/hyperactivity disorder, oppositional defiant disorder, conduct disorder, depression, and violence) assessed in early adolescence could prospectively predict level and change in alcohol and marijuana use. Higher levels of all of the types of psychopathology predicted higher levels of alcohol use, and higher levels of attention-deficit/hyperactivity disorder, conduct disorder, and violence predicted higher levels of marijuana use. Only conduct disorder predicted linear growth in alcohol use, and none of the measures predicted growth in marijuana use. The results suggest that drug use prevention programs should target youths with early symptoms of psychopathology.

Adolescent↗

[Incidence, development and prognosis of atrio-ventricular and intraventricular conduction disorders in acute myocardial infarct].

The incidence, the evolution and the prognosis of conduction disturbances associated with myocardial infarction are described in a serie of 450 consecutive unselected patients hospitalized in a coronary care unit. Pacemaking does not seem to influence largely the natural history of myocardial infarction with conduction disturbances, which is essentially determined by myocardial power failure. Indications of insertion of a pacing catheter are presented.

Acute Disease↗

[Recording of conduction tissue potentials in intraventricular conduction disorders. (apropos of 147 patients)].

147 patients, 31 controls and 116 patients with intraventricular conduction disturbances, have been submitted to an endocardial investigation: HR lengthening in case of bundle-branch block indicates a low diffusion of the conduction disturbances and has a pejorative signification. The most important legthenings of this interval have been observed in the cases with delay in the common trunk of His bundle: -- In case of trunkular delay, 66% of the patients have a HR interval longer than 80 msec, and the average value of HR is 82 msec. -- In the absence of obvious trunkular delay, 8% of the patients only have a HR interval longer than 80 msec, with an average value of 67 msec. For these latter patients no branch potential was recorded. -- In some cases one is certain of the presence of a conduction disturbance of both branches and the HR value then never exceeded 60 msec. -- Branch potential recording makes it possible to determine the site of the conduction disturbance of the branch and show mild variations of the HR interval and of both components.

Action Potentials↗

[Evoked muscle potentials in severe conduction disorders of injured nerves].

In 175 patients with clinical signs of grave impairment of the conductivity, absence of induced muscular potentials has helped to diagnose full anatomic rupture of the nerve, i.e. a case when resection and junction of the nerve by suturing are necessary. The examination of the induced muscular potentials made it possible to specify the degree to which the continuity of the axons inside the nerve trunk was preserved. The amplitude of the induced muscular potentials was lowered down to 0.01 mV. The speed of the stimulus conduction diminished down to 40.0 +/- 9 m/sec in cases of the median nerve damage: to 44.4 +/- 4 m/sec, if the ulnar, and to 11.1 m/sec, if the radial nerve was damaged.

Accessory Nerve Injuries↗