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Fistulisation of an iliac pseudoaneurysm into the appendix. Presentation of a case and a review of the literature.

A case of ilioappendiceal fistula is presented. The patient had previously been operated on for a ruptured aneurysm of the common iliac artery. 21 years later he developed occult gastrointestinal bleeding without signs of infection. Colonoscopy revealed bloody faeces and an isotope scan haemorrhage in the ascending colon. Laparotomy and right hemicolectomy was performed without identifying the fistula. The head of the appendix was left attached to the scarred peritoneal wall. As the bleeding continued, a second laparotomy was performed revealing an iliac pseudoaneurysm with fistulisation into the head of the appendix. Vascular reconstruction was attempted, but the patient succumbed to massive bleeding on the operating table.

Aneurysm↗

Horseshoe anomaly of the appendix: a previously undescribed entity.

Anomalies of the appendix are extremely rare. The case presented here has not been previously described and is that of a "horseshoe" appendix in a 33-year-old man with sigmoid diverticulitis. This appendiceal variant cannot be classified into any of the existing categories of appendiceal anomalies.

Adult↗

[Surgical treatment of malignant tumors of the appendix].

Malignant epithelial tumours of the appendix are rare. They are mostly diagnosed by the pathologist rather than by the surgeon. Very frequently patients with these tumours present themselves with clinical signs of acute appendicitis. Right hemicolectomy is postulated to be the appropriate treatment of choice in all patients with adenocarcinomas of the appendix (colon type, cystic type). On the other hand this radical approach should be applied only to selected cases with carcinoid tumours.

Adenocarcinoma↗

Necrotizing arteritis of the vermiform appendix. A clinicopathologic study of 12 cases.

Necrotizing arteritis of the vermiform appendix (NAVA) is an uncommon condition. There are conflicting reports in the literature about its relationship to systemic polyarteritis nodosa (PAN). In this study, 12 cases of NAVA are described, constituting 0.28% of histologically examined appendixes. Nine of the patients were followed up for a mean of 6.8 years. Systemic necrotizing arteritis was found in three cases, all of which were complicated by secondary ulceration or infarction of the colon. The results strengthen the association between NAVA and systemic PAN. However, it is more meaningful to relate NAVA to the broader group of necrotizing vasculitides rather than exclusively to classic PAN.

Adolescent↗

The effects of Schistosoma haematobium infestation on the vermiform appendix: the Nigerian experience.

In a prospective study of 518 consecutive appendices removed at surgery for symptomatic appendicitis, 32 appendices showed evidence of chronic Schistosoma haematobium appendicitis (a frequency of 6.2%). As the diagnosis can only be confirmed by histology of the removed appendix, the authors believe that in endemic areas chronic S. haematobium appendicitis may not be as rare as the few recorded cases would seem to suggest. Appendiceal mucosal ulceration with chronic inflammatory infiltration and fibrosis of the appendiceal wall leading to chronic appendicitis may be due to intense deposition of ova in the appendix wall, particularly the submucosa, by the adult worm.

Appendicitis↗

[Diverticulosis of the appendix].

Diverticulosis of the appendix. Diverticulosis of the appendix is a rare condition. Cause of the danger of perforation, it is not an unimportant entity. We present six examples and review its pathogenesis, diagnosis and treatment.

Adult↗

Endoscopic appearance of the intussuscepted appendix and accurate preoperative diagnosis.

Intussusception of the appendix in a 25-yr-old man was diagnosed preoperatively. Only six such cases have been reported. This patient presented with episodes of recurrent severe right lower abdominal pain, each episode separated by several uneventful months. The diagnosis was made by radiological visualization of a polypoid lesion with a dimple at the top in the caput cecum, and by the endoscopic appearance of the polypoid mass. A sessile polypoid mass (about 1 cm) that looked like foreskin and glans was observed by colonoscopy. The dimple at the top, like glans, was partially reddish, and the steeply sloped surface, like foreskin turned inside out, was smooth. The area of dimple at the top became discernibly smaller and the appearance changed as air was led into cecum. Appendectomy was without untoward events, and the patient no longer experienced such episodes. Although intussusception of the appendix is rare, it should be included in the differential diagnosis of acute abdominal syndrome.

Adult↗

[Absence of the appendix. Apropos of a case].

A case of congenital absence of the appendix is reported by the authors. It is a very rare anatomic finding, the frequency of which is about 1 p. 100 000. The awareness of this malformation must not authorize young surgeon to forsake a difficult search of the appendix. The diagnosis should not be made unless the entire right colon and the ileo-cecal area are mobilized and thoroughly explored.

Adult↗

[Primary cancer of the vermiform appendix--case report and literature review].

The case history of an eighty one year old white male with progressive cachexia and massive ascites is given. Autopsy revealed the rare finding of a primary adenocarcinoma of the appendix with multiple metastases as the cause of the rapidly deteriorating clinical condition. The incidence, clinical findings and therapeutic options in carcinoma of the appendix are discusses based on a review of the literature.

Adenocarcinoma↗

Conservative management of appendix mass in children.

Of 834 children who had appendicectomy for appendicitis 77 (9.2%) had developed an appendix mass when first seen. Under 6 years of age 25% of appendicitis patients had an appendix mass at presentation and almost 60% of the masses seen were in patients under six years of age. Forty three of the 77 masses (55%) were palpable only under anaesthesia. The masses were all initially managed conservatively by bed rest, intravenous fluids and intravenous antibiotics. All but eight (10%) of the 77 patients responded to this form of treatment. Interval appendicectomy was planned for a date 4 weeks following discharge. The overall total average bed stay including interval appendicectomy was 16 days. There were no late complications or relaparotomies.

Abscess↗

Mucocele of the appendix.

The history of two patients with a mucocele of the appendix is reported. It is stressed that in case of a tumour of the appendix the possibility of a malignant mucocele should always be considered. To prevent a peritoneal pseudomyxoma tumour spill should be avoided and great care should be taken in performing appendectomy. A survey of the literature is given.

Aged↗

[Crohn's disease of the appendix].

22 cases of primary involvement of the appendix in Crohn's disease are reported in the literature. During the last 3 years we observed 4 cases. In three patients typical clinical signs of acute appendicitis were present. One case was found occasionally. The follow-up was 5-30 months. During this time none of our patients showed symptoms of granulomatous enterocolitis in other regions of the bowel. Reviewing the literature 3 of 26 patients (11.5%) showed lesions typical for Crohn's disease elsewhere in the intestine 3-48 months after appendectomy. But two cases had a follow-up of 5 years which time is considered indispensable before one can admit that the disease is really limited to the appendix.

Adolescent↗

Diverticulum of the vermiform appendix. A review of 28 cases.

Twenty-eight previously unreported cases of appendiceal diverticula were found in a 15-year retrospective review of records at five hospitals. The incidence is probably higher than is realized. Data drawn from the review indicated that the age of the patient and a history of previous attacks might be slight clues to distinguishing between diverticulum and acute appendicitis. Inflamed or not, rarely are these diverticula recognizable at the time of operation, but if the appendix is bulbous or club-shaped or there is increased thickening of the mesentery, the surgeon's suspicion should be aroused. In four of fourteen acute cases in the series, perforation had occurred-within 15 hours of the onset of symptoms in two cases. In four others there was abscess formation within the mesentery of the appendix.

Adolescent↗

Histochemical enzymatic assessment of the human appendix at different ages.

The appendectomy specimens submitted to surgical pathology exhibit a wide variety of morphological appearances. We have evaluated the activities of acid phosphatase, alpha-naphthyl esterase, and leucineaminopeptidase in 100 human appendixes divided into six age groups in order to ascertain whether any histochemical pattern was related to the age group rather than to pathological condition. Our findings support that the submucosal fibrosis is unrelated to the patient's age, as well as appendiceal obliteration. It is noteworthy that the mucosa of the appendix may retain its lymphoid constituents at any age and that young subjects may already show appearances of involution up to lumen obliteration.

Acid Phosphatase↗

[Age and the anatomy of lymph nodule groupings in the human appendix].

The appendices from 121 corpses of persons died at the age 1 day--83 years have been studied. Increase in number and size of the lymph nodules in the appendix wall takes place up to 16 years of age. At the same age there is a certain increase in arrangement density of the lymph nodules from the base of the organ towards its apex. In childhood and adolescent age, in histological sections, the grouped lymph nodules are often arranged in 2-3 layers. The form of the nodules in transversal sections of the appendix in children and adolescents is round, oval and piriform, and at mature age and especially in aged and old persons, most of the nodules are flattened and elongated in transversal direction. The germinative centers are present in most of the lymph nodules in children up to 16 years of age, their number is less in mature persons and they are absent in the nodules in aged and old persons.

Adolescent↗

[Large mucocele of the appendix imitating an ovarian cyst].

Mukokela appendix--described by Rokitansky in 1842 for the first time--appears in 0,2% of appendectomy at Bulovka-Hospital Prague. Great mukokela appendix (12,5 x 5,5 cm), which resembled ovarial cyst on the right hand side, had been found for the first time in 20 years. The patient was a 63 old woman; she was cured in 9 days after appendectomy. The authors describe etiology, clinic and the case itself.

Appendectomy↗

[Structural and immunomorphological characteristics of the human fetal appendix].

Altogether 120 human 12-31 week-old embryonal appendices were examined by histological, histochemical and immunomorphological methods. It was demonstrated that the first lymphoid follicles in the appendix occur in a 17-week-old embryo. Beginning from this time mononuclear suspension can be isolated from the organ and T and B lymphocytes defined. The features of the intestinal mucosa areas where lymphocytes are reproduced, released into the intestinal lumen and eliminated from the organs via the vessels are described. In mononuclear suspension, T and B lymphocytes are demonstrated, first in equal amounts whereupon the percentage of B lymphocytes rises to 26%, while the T lymphocyte count remains within 18%. The authors do not regard the appendix as an analog of the Fabricius bursa but attribute it to the peripheral organs of the immunity system.

Appendix↗