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PubMed2002

Simultaneous toe-to-hand transfer and lower extremity amputations for severe upper and lower limb defects: the use of spare parts.

From 1995 to 2000, five microvascular toe-to-hand transfers were performed in three children who were simultaneously undergoing lower extremity amputations. Their ages at time of transfer ranged from 4 to 10 years and the types of lower extremity amputation included toe amputation, foot amputation and through-knee amputation. The resulting toe-to-hand transfers included three great toe-to-thumb transfers and one combined great and second toe-to-hand transfer. The toe-to-hand transfers were all successful and all the lower extremity amputations healed without complications. In all cases, improved hand function and lower extremity function was noted by the families. These unique cases represent the ultimate use of spare parts in congenital hand surgery.

Amputation, Surgical↗
PubMed2006

[Incidence of major amputations, bypass procedures and percutaneous transluminal angioplasties (PTA) in the treatment of peripheral arterial occlusive disease in a German referral center 1996-2003].

PURPOSE: To determine the current incidence of major amputations, bypass procedures and percutaneous transluminal angioplasties (PTA) in a study population of patients with peripheral arterial occlusive disease in a German referral center. MATERIALS AND METHODS: In a retrospective study, we recruited patients with peripheral arterial occlusive disease who underwent an amputation, bypass procedure, or PTA in the region of the pelvis or lower limbs between 1996 and 2003 at the Augsburg Medical Center. Patients were identified via the hospital database. This was performed with the help of the International Classification of Diseases (ICD 9 and 10), the operation code (OPS), and appropriate invoices. The incidence of PTAs was further estimated with 200 charts. RESULTS: Of 5379 patients, 627 underwent amputation, 1832 a bypass procedure, and 2920 a PTA. The incidence of PTAs increased during the study period from 51.3/100 000/year to 64.4/100 000/year (p < 0.01), while the number of amputations and bypass procedures remained stable. The incidence of PTAs was exceeded by that of bypass procedures only in patients older than 85 years. The age of the amputees decreased during the study period from 72.2 to 70.5 years (p < 0.01). The age of patients who underwent a bypass procedure increased from 67.2 to 69.4 years, and the age of patients who underwent PTA increased from 66.3 to 69.8 years (p < 0.01). Bypass procedures and PTAs were performed in men 6.3 years earlier than in women (p < 0.01). CONCLUSION: The result is a population-corrected need of 8.4/100 000/year major amputations, 23/100 000/year bypass procedures and 64.4/100 000/year PTAs for patients with peripheral arterial occlusive disease within the referral area of our hospital. The performance of major amputations and bypass procedures stagnates, while the incidence of PTAs is increasing.

Adult↗
PubMed1985

Oxygen inhalation--induced transcutaneous PO2 changes as a predictor of amputation level.

Noninvasive transcutaneous PO2 (TcpO2) determinations have been developed to study peripheral arterial occlusive disease. To evaluate this technique as a predictor of amputation outcome, a blind, prospective study of 101 patients undergoing 119 amputations (23 above-knee [AK], 57 below-knee [BK], and 39 forefoot) was performed. TcpO2 measurements were obtained from the dorsum of the foot and 10 cm distal to the patella, both prior to and 10 minutes after inhalation of 100% oxygen. On the basis of preliminary results, initial TcpO2 values greater than 10 mm Hg or an increase greater than 10 mm Hg after oxygen inhalation were considered to predict a successful outcome, whereas failure was predicted when the initial TcpO2 value was less than 10 mm Hg and the increase after oxygen inhalation did not exceed the 10 mm Hg level. In the BK amputation group the test was 95% sensitive, 100% specific, and 95% accurate. Retrospective utilization of the above criteria in patients who had undergone both oxygen inhalation testing and AK amputation suggested that 9 of 17 limbs (53%) might have undergone a more distal BK amputation successfully. These results document the effectiveness of an initial TcpO2 determination coupled with the response to 100% oxygen inhalation as an excellent predictor of the outcome of lower extremity amputations.

Adult↗
PubMed1992

Criteria for reliable selection of the lowest level of amputation in peripheral vascular disease.

To improve the chances for the amputee to become ambulatory the most distal level of amputation should be selected in patients with end-stage peripheral vascular disease. Physical examination alone provides insufficient information when amputation levels are closely related to areas with signs and symptoms of ischemia. In the present series of 85 lower extremity amputations the predictive values of clinical parameters and skin perfusion pressure measurements are assessed. The role of clinical judgment is clarified: the most distal level of amputation is to be selected by physical examination, but further information is required to assess the healing potential at the selected level. The presence of palpable pulses immediately above the selected level correlates well with primary wound healing (p less than 0.001, negative predictive value 100%). The absence of palpable pulses and angiographic patency scores are of no clinical value in amputation level selection. Skin perfusion pressure measurements were of excellent predictive value (p less than 0.001, positive predictive value 89%, negative predictive value 99%). According to these data a strategy is proposed for routine determination of the lowest level of amputation, where primary wound healing can be expected.

Adult↗
PubMed1993

Functional foot salvage after extensive plantar excision and amputations proximal to the standard transmetatarsal level.

PURPOSE: It is generally accepted that when necrosis extends proximal to the transmetatarsal level a viable and functional foot can no longer be preserved and a major (above- or below-knee) amputation must be performed. However, with continuing advances in operations for limb salvage we felt the need to reexamine this concept. METHODS: In 1983 we initiated a prospective study to evaluate the role of extended foot amputations. All ambulatory patients with necrosis extending proximal to the transmetatarsal level (but not involving the whole foot) were included in the study. Among the 21 patients studied amputations ranged from open guillotine transmetatarsal amputation to removal of the medial or lateral three fifths of the foot. Five of these patients had adequate pedal circulation by clinical and laboratory criteria. The remaining 16 required vascular reconstruction to improve pedal flow. RESULTS: Eighteen (86%) of 21 patients had complete healing of the foot amputations and were ambulatory at the time of discharge from the hospital. Two patients required early above- or below-knee amputations. Three additional patients sustained limb loss in the follow-up period. The cumulative graft patency rate was 94% at 12 months. The cumulative limb salvage rate at 24 months was 84%. The operative mortality rate was 1 (5%) of 21. CONCLUSION: Our experience in a small number of patients suggests that functional foot salvage is possible even when necrosis or gangrene extends proximal to the transmetatarsal level.

Aged↗
PubMed2001

The value of toe pulse waves in determination of risks for limb amputation and death in patients with peripheral arterial disease and skin ulcers or gangrene.

OBJECTIVES: The purpose of this study was to determine whether the presence of low amplitude of pulse waves recorded from the toes is related to the risk of subsequent amputation and death in patients with skin ulcers or gangrene and peripheral arterial disease, and how the risk of low wave amplitude relates to the risk associated with low peripheral pressures. METHODS: A total of 309 patients with 346 limbs with skin lesions and arterial disease referred to the vascular laboratory were followed up for an average of 5 years (range, 1-8 years). Measurements were carried out to obtain ankle and toe pressures, pressure indices, and toe pulse wave amplitude. These variables were related to the risks of major amputation and total and cardiovascular death by means of the Cox proportional hazards model. RESULTS: Low toe pulse wave amplitude (< or = 4 mm) was associated with increased risk of amputation (relative risks 4.20 in all limbs and 2.63 in those with toe pressure < or = 30 mm Hg; P <.01). Wave amplitude remained significantly associated with increased risk of amputation after controlling for each pressure variable (P <.01). Low pulse wave amplitude and toe/brachial index were associated with increased risks of both total and cardiovascular death in all patients (relative risks ranged from 1.43-1.73; P <.05) and in those with toe pressure of 30 mm Hg or less (relative risks 1.56-1.90; P <.05). CONCLUSIONS: Low toe pulse wave amplitude is related significantly to increased risks of amputation and death in patients with skin lesions and arterial disease. The presence of low wave amplitude provides significant information in addition to peripheral pressures with respect to the risk of amputation.

Aged↗
PubMed2004

Method for estimating body weight in persons with lower-limb amputation and its implication for their nutritional assessment.

BACKGROUND: Body weight is a good indicator of a person's size and is widely used in clinical assessment. However, health-status assessment based on observed body weight (W(O)) is incorrect for persons with limb amputation. OBJECTIVES: The objectives were 1) to develop a more accurate and generalized method for estimating body weight in persons with limb amputation, 2) to determine whether corrected body weight can be used to assess nutritional status in persons with limb amputation, and 3) to test the validity of the estimation by using empirical data. DESIGN: Anthropometric data were collected from men from Calcutta and adjoining areas with unilateral lower-extremity amputation (n = 102). Mathematic formulas were developed for determining estimated body weight (W(E)) and body mass index (BMI) calculated from both W(O) and W(E) (ie, BMI(O) and BMI(E), respectively). We assessed nutritional status by using BMI(O) and BMI(E) and tested the validity of each by considering the result of nutritional assessment from midupper arm circumference as the gold standard. We also compared the nutritional status results for the subjects with limb amputation with those for a similar sample size of healthy control subjects. RESULTS: BMI(E) had a stronger association with midupper arm circumference and a higher efficiency (ie, proportion of correct results given by any test method) than did BMI(O). Moreover, the results obtained with BMI(E) were similar to those obtained with BMI in healthy control subjects. However, the nutritional assessments made with BMI(O) and BMI(E) did not differ significantly from one another. CONCLUSION: For persons with limb amputation, W(E) provides a better basis for appropriate nutritional evaluation than does W(O).

Adult↗
PubMed1984

Amputation risk factors in concomitant superficial femoral artery and vein injuries.

Only a small subset of patients with combined superficial femoral artery and vein injuries results in amputation. The importance of the venous component as a risk factor for amputation is uncertain. Ligation vs. reconstruction of venous injuries is controversial. For clarification of these issues, we analyzed retrospectively multiple risk factors for amputation in combined superficial femoral artery and vein injuries in a civilian population. There were 25 patients treated in a 20-year period. Sixteen injuries were caused by small caliber missiles, six by shotgun blasts, and three by knife wounds. Three patients (12%) ultimately underwent amputation. The major risk factor for amputation was method of vascular reconstruction. All three amputations underwent ligation of the superficial femoral vein with arterial reconstruction by placement of a reversed interposition saphenous vein graft (p = 0.0009). None of the remaining 22 patients with salvaged limbs underwent reconstruction by this combination of techniques. Consequently, the authors emphasize the importance of venous reconstruction, particularly in combined injuries with major arterial involvement requiring interposed grafts.

Adolescent↗
PubMed2002

Comparison of quality of life after amputation or limb salvage.

In the past, amputation was the standard method of treatment for patients with sarcomas in the extremity but limb-sparing procedures now are much more frequent. A computerized questionnaire automatically adjusted for gender, age, diagnosis, site, and treatment was sent to 2200 patients with high-grade sarcomas who had been treated during the past 25 years. Using the data, it was possible to study and compare the response from 66 patients who had an amputation and 342 patients with a limb-sparing procedure for a lower extremity neoplasm. More males had an amputation, but no differences were observed in the ages of the two groups. The outcomes for the two groups were similar. Patients who had limb-sparing procedures did not have a significant improvement in the ability to ambulate, climb stairs, drive a car, or be employed. More of the patients with amputations required walking aids and participated in sports activities at almost the same rate as the patients who had limb-sparing procedures. Patients who had amputations had no more anxiety, drug-dependence, depression, sleep problems, or limitation of sexual performance than patients who retained their limbs. The patients with amputations had more children and fewer menstrual problems; however, they were far less satisfied with their status at early ages than at later periods in their lives.

Adolescent↗
PubMed1996

Amputation versus reconstruction in traumatic defects of the leg: outcome and costs.

This retrospective review covers global aspects of reconstructive efforts to salvage severely injured legs. Eighteen patients with traumatic lower leg amputation were compared to 21 patients who underwent complex microvascular reconstruction. The mean number of interventions was 3.5 for amputation and 8 for reconstruction (p < 0.009). Total rehabilitation time was 12 months for amputation and 30 months for reconstruction (p < 0.009). Changes in lifestyle were consistently more important in the amputee group. The mean annual hospital costs for amputated patients were 15,112 Swiss Francs (SD 7,094 SF) for the first 4 years. The mean annual hospital costs for reconstructed patients were 17,365 Swiss Francs (SD 8,702 SF) for the first 4 years. Fifty-six percent of the amputees and 19% of the reconstructed patients were retrained to a different profession (p < 0.025). Fifty-four percent of the amputees and 16% of the reconstructed patients were drawing an extremely costly and life long invalidity pension (p < 0.02). We conclude that for potentially salvageable legs reconstruction is advisable because the functional outcome was better than for amputation and there was no permanent social disintegration due to the long treatment. Total costs (including pensions) for reconstruction were far lower than for amputation.

Adolescent↗
PubMed1994

Extent of disability following traumatic extremity amputation.

Extremity amputation is a devastating injury. Forty-two patients who sustained traumatic limb amputation were contacted 3-57 months (mean, 25 months; median, 24 months) after injury to evaluate residual disability and to determine what factors were associated with a good recovery. There were 35 men and 7 women with ages ranging from 5 to 73 years (mean, 34 years). Amputation was the result of a motor vehicle crash in 18, work-related injury in 11, motorcycle crash in 9, and other causes in 4. There were 46 amputations done: 8 above-knee (AK), 25 below-knee (BK), 5 above-elbow (AE), and 9 below-elbow (BE). Twenty patients reported no problems with their prosthesis, 8 had major (e.g., infections) and 6 had minor (e.g., skin breakdown) problems. Eight patients did not receive or did not use a prosthesis. Fourteen patients were discharged to an inpatient rehabilitation facility, 25 to home with outpatient rehabilitation, and 3 had no rehabilitation. Of those who worked before their injury, only 50% returned to work. The mean and median time to return to work were 14 and 12 months, respectively. Three of five full-time students returned to school. The amputation level in patients returning to work or school was BK in 12, BE in 3, and AE in 1. No patient with a AK amputation and only 1 (9%) patient with a work-related injury returned to work. Associated injuries or inpatient rehabilitation did not correlate with returning to work. Eighty-eight percent of patients were satisfied with their adjustment and could perform all activities of daily living.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1986

Traumatic amputations in the workplace.

The purpose of this study was to identify variables associated with traumatic amputations in the workplace. Case files of work-related amputations in Minnesota during 1977 were accessed in cooperation with the Workers' Compensation Division of Minnesota. Data analysis was conducted by computer using the Statistical Package for Social Sciences. Of the 109 amputation cases, a mean age of 31 years (range 16 to 80) was identified; 50% of all cases were below the age of 25 years. By gender, males accounted for five times as many cases as females. Operatives incurred the largest number of amputations (40%); yet, they account for only 14% of the total work force. Manufacturing accounted for a majority (43.4%) of the traumatic amputations while including only 18 percent of the work force. Prevention strategies employed subsequent to the injuries included: training only (32.1%), engineering controls (10.1%), and mixed strategies (3.0%); further analysis revealed that although application of passive controls to the specific source (eg, machine) of the injury would have been most appropriate, training was frequently the only intervention incorporated. Recommendations, including Haddon's strategies for prevention and control of amputations are presented.

Accidents, Occupational↗
PubMed2004

Postoperative mortality after nontraumatic lower extremity amputation in patients with renal insufficiency.

Mortality rates after lower extremity amputation are extremely high among dialysis patients. However, the impact of milder degrees of renal insufficiency on death rates after lower extremity amputation has not been carefully examined. In this study, the authors used data from the Department of Veterans Affairs' National Surgical Quality Improvement Program (NSQIP) to measure the association between renal dysfunction and 30-d mortality after nontraumatic amputation adjusted for confounders. The study population consisted of 16,994 patients undergoing their first NSQIP recorded amputation from January 1, 1994 through September 30, 2001. Thirty-five percent of all cohort patients had at least moderate renal insufficiency, and 52% of all postoperative deaths occurred in this group. Postoperative mortality was 9% in patients with moderate renal insufficiency, 15% in patients with severe renal insufficiency, and 16% in dialysis patients, compared with 6% in patients with normal or mildly reduced renal function. Renal insufficiency remained associated with death after adjustment for confounders (adjusted odds ratio [OR] 3.36, 95% confidence interval [CI] 2.75 to 4.10 [dialysis patients]; OR 2.54, CI 2.06 to 3.14 [severe renal insufficiency]; and OR 1.52, CI 1.32 to 1.76 [moderate renal insufficiency]). In conclusion, even moderate renal insufficiency is independently associated with postoperative death after lower extremity amputation. This finding highlights the need for a targeted approach to improving the care of patients with renal insufficiency undergoing lower extremity amputation.

Aged↗
PubMedDate not supplied

Burns and amputations: a 24-year experience.

Although the management of the severely burnt extremity poses a significant therapeutic dilemma, burn injuries resulting in amputation are uncommon, In such cases, however, amputation can reduce the rate of mortality. In a total of 1858 patients from January 1980 to January 2004, there were 34 amputations in 27 patients. There were 23 men (age range, 14-64 years) and 4 women (age range, 34-85 years). The majority of amputations from burns caused by flame injury predominantly after motor vehicle accidents, with only eight cases resulting from high-voltage electrical injury. Nine patients required immediate amputations, with the rest being delayed. There were three deaths, with a survival rate of 89%. The majority of single lower-limb amputees and only one of seven bilateral amputees were independently mobile. The presence of pre-existing psychiatric disease significantly impaired rehabilitation. Free tissue transfer and the usage of bioengineered materials may help reduce the incidence of amputations.

Adolescent↗
PubMed2006

Initial nontraumatic lower-extremity amputations among veterans with diabetes.

RESEARCH OBJECTIVE: We sought to identify initial nontraumatic lower-extremity amputations (ILEAs) and compare rates of ILEAs with different coding algorithms and varying lengths of observation period prior (look-back) to the first observed amputation. STUDY DESIGN: We used a retrospective design on merged Medicare claims and patient treatment files of the Veteran Healthcare Administration for fiscal years 1998 to 2000 of veterans with diabetes ages 18 years and older. Three different algorithms using least-inclusive to most-inclusive procedure codes and "look-back" periods of 12, 18, and 24 months were used to identify ILEAs. FINDINGS: Overall, 2997 (8.2 per 1000) veterans experienced an amputation in fiscal year 2000. Using 24 months of previous data, the rates of ILEA under the 3 different algorithms I, II, and III were 6.4/1000, 6.2/1000, and 6.0/1000 respectively. Using the most stringent algorithm (III), ILEA rates were 6.6/1000 with 12 months of prior data, 6.2/1000 with 18 months of prior data. Compared with any amputations in fiscal year 2000, 12-, 18-, and 24-month look-back period decreased the ILEA rates by 19%, 24%, and 27%, respectively. CONCLUSION: These findings highlight the usefulness of administrative data in identifying ILEAs. All 3 algorithms performed comparably well in the detection of ILEAs. The extent of identification was most complete with 24 months prior data, with marginal gains in extending the prior observation period from 18 to 24 months. Policy level analysis should consider reporting ILEAs, in addition to total amputation rates when examining trends and disparities in amputations.

Adult↗
PubMed2005

Reliability and validity of a self-report FIM (FIM-SR) in persons with amputation or spinal cord injury and chronic pain.

OBJECTIVE: To evaluate the reliability and validity of a self-report FIM (FIM-SR) in two samples of adults with disabilities. DESIGN: Participants in a clinical trial of amitriptyline for pain (n = 84 with spinal cord injury [SCI], n = 38 with amputation) provided responses to the study measures via telephone interview. Reliability was estimated using Cronbach's alpha and test-retest correlation coefficients, and validity was examined by comparing FIM-SR scores with the Craig Handicap Assessment and Reporting Technique (CHART) by comparing the CHART scores between the participants with SCI and amputation, and by comparing CHART scores between subjects with different levels of SCI. RESULTS: In the SCI sample, the FIM-SR demonstrated adequate reliability, and correlational analyses supported the validity of the FIM-SR motor scales. In addition, the FIM-SR motor scales discriminated subjects with different diagnoses (SCI vs. amputation) and injury levels (paraplegia vs. tetraplegia). The psychometric properties of the entire FIM-SR in the amputation sample and of the FIM-SR cognitive scales in the SCI sample were difficult to determine due to a ceiling effect in which these scale scores were skewed toward the top end of the range. CONCLUSIONS: The FIM-SR motor scales and total FIM-SR score are reliable and valid measures of perceived functional independence in individuals with SCI. However, all of the FIM-SR scales in the amputation sample, and the FIM-SR cognitive scales in the SCI sample, seem to be less useful measures of functioning due to subjects reporting high levels of independence. The FIM-SR should be retested in amputation samples with more variable levels of functioning.

Adult↗
PubMed2003

Long-term results of replantation for complete ring avulsion amputations.

Ring avulsion injuries have long presented complex management problems. Despite microsurgical advances, it is difficult to achieve good functional results in complete degloving injuries or amputations, and their management remains somewhat controversial. Ten patients with class IV injuries according to Kay's classification were treated from 1986 to 2000. In this study the authors subdivided class IV injuries into those with amputation distal to the insertion of the flexor digitorum superficialis tendon (class IVd, 5 cases); those with amputation proximal to the insertion of the flexor digitorum superficialis tendon (class IVp, 3 cases); and complete degloving injuries leaving the tendons intact (class IVi, 2 cases). Replantation was done in class IVi and class IVd injuries, and 6 cases were revascularized successfully. In all these patients range of motion was complete at the metacarpal and proximal interphalangeal joints, but reestablishing sensibility was more difficult. Patients with class IVp injuries were treated by surgical amputation of the digit. Modifications of Kay's classification system based on anatomic injury is more predictive of functional outcome for completely amputated ring avulsion injuries. The authors conclude that complete ring avulsion amputations are salvageable, with acceptable functional results in select patients.

Adult↗
PubMed1983

Railyard amputations in children.

Railyard or train-related accidents are a common cause of traumatic amputations in children. Four consecutive children with traumatic lower extremity amputations due to railyard amputation seen between 1975 and 1980 demonstrated: a common mechanism of injury--all were attempting to obtain rides on slow-moving trains near their homes or school; similar lower extremity amputation patterns--four right below knee and two left Syme's amputations; and distinctively abnormal psychosocial backgrounds. The psychosocial abnormalities have been demonstrated to be unique in children sustaining traumatic railyard amputations and are probably contributory. Awareness of these factors is important when considering surgical intervention and in planning for long-term rehabilitation.

Accidents↗