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[Tecoma].

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Bignoniaceae↗

Granulosa-theca cell tumor associated with an ovulation fossa and normal ovarian stroma in a mare.

A granulosa-theca cell tumor was found in an ovary that had an ovulation fossa and normal ovarian tissue. The ovary was removed from a mare with a history of ovarian enlargement and behavioral changes. The affected ovary had a multicystic appearance on ultrasonographic examination performed before surgery, and an ovulation fossa was not palpable on examination per rectum. However, during surgery, the affected ovary was found to be within normal size limits, with an enlargement on 1 pole, and to contain an ovulation fossa. Atrophy of the infundibulum of the affected ovary helped to confirm the diagnosis of granulosa-theca cell tumor, and the ovary was removed. The mare's testosterone concentrations were normal. Granulosa-theca cell tumors are usually associated with a spherical ovary, attributable to ablation of the ovulation fossa, with no normal ovarian tissue present.

Animals↗

[Serum testosterone level in the diagnosis of virilizing ovarian neoplasms].

The paper is concerned with the results of investigation of 15 patients with virile ovarian tumors (VOT). The following methods were employed for instrumental diagnosis: USI, computerized tomography and laparoscopy. Hormonal investigation included the determination of basal levels of serum testosterone (T), excretion with urine of 17-ketosteroids and their time course against a background of suppression tests with dexamethasone and stimulation tests with CG. The results of hormonal investigations were compared with those of similar investigations of 14 patients with stromal ovarian thecomatosis and 8 patients with androgen producing adrenal tumors. Ovarian tumors were detected in 40% by instrumental and clinical methods. Hormonal studies revealed a high level of T in patients with virile ovarian and adrenal tumors exceeding 3-3.8-fold a similar indicator in patients with stromal thecomatosis. All patients with a "tumor" level of T underwent laparotomy after excluding an adrenal lesion. Ovarian tumors of 1.0-2.5 cm in diameter were detected.

17-Ketosteroids↗

[Stromal luteoma of the ovary. Differential diagnosis of steroid cell tumors].

An observation of a stromal luteoma of the ovary is reported. It is a rare tumor (only about thirty cases of it have been published yet), occurring mostly in post menopausal women. Endocrine symptoms and sometimes virilizing signs may be observed. Abnormal vaginal bleeding is the most frequent clinical manifestation. This macroscopically observed tumor is surrounded by ovarian stroma and entirely composed of luteinized cells devoid of crystals of Reinke. Hyperthecosis of ovarian stroma is often observed. Its evolution is always benign. The authors recalled the place of stromal luteoma of the ovary among steroid (lipid) cell tumors and the elements of a differential diagnosis. These tumor might derive from ovarian stromal cells.

Adrenal Rest Tumor↗

[Luteinized cystic hyperplasia of the ovaries during pregnancy. A case report].

Multiple lutein cyst (MLC) and luteoma are two aspects of ovarian hyperplasia induced by high levels of human chorionic gonadotrophin (HCG). Using a case report of MLC, the authors compare it with luteoma (the anatomoclinical and pathogenic data). Luteoma are more frequent with multipara, whereas MLC are more often seen with paucipara. Maternal virilization can occur in both cases but MLC does not seem to be responsible for fetal virilization. The fetus could be protected by the placenta, thanks to increased aromatase activity and sex binding globulin production. MLC and luteoma are usually found by chance. The pathology must be known, because of their spontaneous regression after delivery. So, the attitude will be conservative under the control of biopsies.

Adult↗