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Calculation of porosity and osteonal cement line effects on the effective fracture toughness of cortical bone in longitudinal crack growth.

Based on the microscopic analyses of cracks and correlational studies demonstrating evidence for a relationship between fracture toughness and microstructure of cortical bone, an equation was derived for bone fracture toughness in longitudinal crack growth, using debonding at osteonal cement lines and weakening effect of pores as main crack mechanisms. The correlation between the measured and predicted values of fracture toughness was highly significant but weak for a single optimal value of matrix to cement line fracture toughness ratio. Using fracture toughness values and histomorphometrical parameters from an available data set, matrix to cement line fracture toughness ratio was calculated for human femoral bone. Based on these calculations it is suggested that the effect of an osteon on fracture toughness will depend on the cement line's ability to compensate for the pore in an osteon. Matrix to cement line fracture toughness ratio significantly increased with increasing age, suggesting that the effectiveness of osteons in energy absorption may be reduced in the elderly due to a change in cement line properties.

Aged↗

Preparation of high-surface-area zinc oxide with ordered porosity, different pore sizes, and nanocrystalline walls.

Transition-metal-oxide materials possessing ordered mesoporosity have recently attracted significant research interest due to their numerous potential applications. Among them, ordered mesoporous zinc oxide (ZnO) is a very tempting material because of the importance of ZnO in heterogeneous catalysis. Here, first results of the preparation of ordered mesoporous ZnO materials by using different templates are reported. Porous materials with high surface area, different pore sizes, and nanocrystalline ZnO walls were obtained. Furthermore, we compare the two fundamental templating techniques, involving liquid crystals or ordered mesoporous carbon materials as templates. Regarding the formation of mesoporous ZnO, it was evident that the hard-matter carbon template is superior.

Journal Article↗

The role of pH and membrane porosity in preparative electrophoresis.

The Gradiflow is a preparative electrophoresis apparatus, allowing fractionation based on a combination of size and charge of proteins in their native (unreduced) form. The preparative fractionation of two proteins of similar size and isoelectric point is demonstrated using the Gradiflow. A separation membrane of appropriate pore size was chosen and then fractionation was "fine tuned" by selecting an appropriate buffer pH to accentuate charge differences between the proteins of interest. Complete separation of mg quantities of bovine serum albumin and ovalbumin was achieved within 40 min.

Electrophoresis, Polyacrylamide Gel↗

On the characterization of porosity in PTFE-carbon composite implant materials by mercury porosimetry.

Questions have been raised about the use of mercury intrusion porosimetry to measure interconnecting pore sizes and void volumes in relatively soft and flexible materials such as porous implant composites of PTFE and carbon fibers. We have studied the effect of precompression of one such commercial composite on the mercury intrusion curves which cover all pore diameters greater than about 16 microns, the range of interest for tissue ingrowth applications. Prior compression by a pressure 20% greater than that encountered by the material during a mercury intrusion experiment did not change the ensuing pore size distribution curve, as compared with a noncompressed sample. Deformation of the material at higher pressures sufficient to decrease the sample volume inelastically by 17, 33, and 67% changed the shape of the mercury intrusion curves significantly, indicating that this technique can be used to detect prior deformation of an "unknown" sample. In the undeformed material, less than 15% of the total void as measured by mercury porosimetry consists of interconnecting pores greater than 100 microns in diameter and more than 50% of the void volume is composed of pores less than 40 microns in diameter.

Biocompatible Materials↗

Porosity of surgical mesh fabrics: new technology.

A new method using an image processing system developed in our laboratories is used to measure the pore size in Mersilene, Marlex, and Teflon surgical meshes. All three meshes appear to have sufficiently large pores and should facilitate tissue growth/attachment. Results obtained in this study are compared to results of an earlier paper.

Image Processing, Computer-Assisted↗

The Effect of Alcohol Solvents on the Porosity and Phase Composition of Titania.

Bimodally porous titania powders were made by hydrolysis of titanium tetraisopropoxide (TTIP) dissolved in various alcohols (methanol, ethanol, isopropanol, and sec-butanol). The specific surface area (SSA) of the powders dried at 150 degrees C ranged from 332 to 624 m(2)/g as determined by nitrogen adsorption. At excess alcohol concentration, the SSA of the dried powders decreased in the order of sec-butanol, iso-propanol, ethanol, and methanol at a constant alcohol/TTIP molar ratio. The pore size distribution was bimodal with fine intraparticle pore diameters at 1-6 nm and larger interparticle pore diameters at 30-120 nm as determined by nitrogen adsorption isotherms. The average intraparticle pore diameter decreased with increasing alcohol concentration for methanol and ethanol, while it was rather constant at 3.3 nm, irrespective of alcohol concentration for iso-propanol and sec-butanol. The evolution of particle phase composition was determined by X-ray diffraction ranging from amorphous to crystalline anatase and rutile largely proportional to the calcination temperature and to a lesser extent on the type and concentration of alcohols. Copyright 2000 Academic Press.

Journal Article↗

Dissolution Effects on Specific Surface Area, Particle Size, and Porosity of Pentelic Marble.

Dissolution of natural stone such as marble is not limited to its surface. The porous structure, known to play an important role in stone decay, is also affected by the conditions of dissolution. In the present work, the changes in pore size distribution of Pentelic marble particles accompanying chemical dissolution in undersaturated solutions and at alkaline pH 8.25 were investigated. The specific surface area and the mesopore distribution of the Pentelic marble tested showed a pronounced decrease to very low values. On the other hand, the sizes of macropores exhibited a tendency to increase with the extent of dissolution due either to dissolution in the interior of the pores or to fusion of small pores into larger. Furthermore, the number of small particles decreased significantly, reaching complete disappearance, depending on the extent of dissolution. At the same time, the relative number of particles of intermediate size increased. Copyright 2001 Academic Press.

Journal Article↗