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PubMed1999

[Generalized convulsions in a patient with polydipsia and severe hyponatremia].

A case of a 40-year-old psychiatric patient is reported. Primarily, he was thought to have epileptic seizures, but demonstrated acute symptoms of severe hyponatraemia, plasma sodium was 106 mmol/l. Treatment was initiated with hypertonic saline until regression of symptoms, followed by slow correction of serum sodium to subnormal level. The patients outcome was good. This treatment is discussed focusing on the importance of an immediate onset, despite that the cause of hyponatraemia may be unknown.

Adult↗
PubMed2001

[Cycle disorders, polydipsia, decline of vision. Is it the fault of the hypophysis?].

Apart from partial or complete insufficiency, further diseases of the pituitary with clinical impact are those associated with hormone overproduction such as acromegaly, Cushing's disease and prolactinoma. The cardinal symptom of pituitary insufficiency or disruption of the female cycle, loss of libido or sexual potency reflecting a lesion of the gonadotrophic axis. Hyperprolactinemia also results in a loss of gonadotrophic function. Macroadenomas of the pituitary gland often give rise to visual field defects, so that an ophthalmological work-up is a must. With the exception of hyperprolactinemia, measurement of basic hormone levels is not always sufficient to detect pituitary diseases. For the establishment of hormone deficiency, therefore, stimulation tests, and for detection of hypersecretion suppression tests, are carried out. Owing to the increasing utilization of cranial MRI, incidental detection of intrasellar tumors, the so-called incidentalomas, is becoming ever more common, and these lesions require at least an endocrinological investigation.

Acromegaly↗