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[Abnormal hemoglobins in a Negroid population in Peru].

A study was performed on 100 blood samples from black people native of the Chincha province and living in Pueblo Nuevo Ica district, in Peru. No haematological abnormalities were seen in any of the cases. Upon haemoglobin electrophoresis, 8 carriers of abnormal haemoglobin were found, the A/S pattern appearing in 5 instances and the A/C pattern in 3. These 8 samples were subjected to deoxyhaemoglobin solubility tests and to differential solubility test with urea, the initial results being confirmed. These data correlate, in general terms with previous findings.

Adolescent↗

[Tuberculin response in school children in Pacasmayo, Peru].

To shed some light on the controversy over the protective effect of BCG vaccine and the usefulness of the tuberculin test in countries with a high prevalence of tuberculosis, in September and October 1987 the test was administered to 440 primary school students in the province of Pacasmayo, Peru. The subjects, both vaccinated with BCG and unvaccinated, ranging from 6 to 10 years of age and coming from rural and urban areas with corresponding vaccination coverage of 55 and 60%, were selected by cluster sampling. The tuberculin reaction was negative in 71% of the vaccinated children and 83% of the unvaccinated children, positive in 16 and 11%, respectively, and inconclusive in the remaining subjects. The results suggest that BCG only prevents progression to the serious forms of the infection. The positive reaction indicates infection or reinfection with Mycobacterium tuberculosis regardless of vaccination status. A negative response in unvaccinated children almost always indicates the absence of infection. The inconclusive results in the unvaccinated children could be the result of a nonspecific allergy and, in the vaccinated children, of persistence of the change produced by M. tuberculosis. The percentage of infected schoolchildren was similar to that in other areas of the country with similar epidemiological characteristics. The tuberculin test appears to be especially important when more than five years have passed since vaccination.

BCG Vaccine↗

Constituents in Erythroxylum coca I: gas chromatographic analysis of cocaine from three locations in Peru.

A method for the determination of cocaine content in coca leaves (Erythroxylum coca) has been developed. The procedure involves refluxing the powdered leaves in 95% ethanol for 15 minutes, followed by acid-base partitioning with chloroform and a GLC assay. The recovery of cocaine was quantitative. This procedure was applied to determine cocaine content in three samples of Erythroxylum coca Lam. collected from different geographic locations in Peru. Using androst-4-ene-3,17-dione as the internal standard the calibration curve was linear over a factor of 0.5 to 10 fold cocaine concentration relative to internal standard. The slope (b) was 0.733, the coefficient of determination (r2) was 1.00 and the average precision was 3.9%.

Chloroform↗

Biosocial responses to seasonal food stress in highland Peru.

This paper examines patterns of seasonal variation in food consumption and responses to food stress in the highland community of Nuñoa, Peru. Dietary and anthropometric data collected from January through August of 1985 on a sample of 26 households (127 individuals) are analyzed. This study finds sharp seasonal differences in energy intake (pre-harvest = 1150 calories/day; post-harvest = 1519/day; p less than 0.01) associated with variation in the availability of locally-produced products (e.g., tubers and cereals). Seasonal energy reduction, however, does not uniformly affect all sectors of this population. Children experience little seasonal change in energy intake and have a more adequate pre-harvest diet and better nutritional status than adults. The responses used to "protect" children from energy stress and minimize the overall impact of seasonal food scarcity on this community include: 1) reduction of pre-harvest household caloric needs through emigration of adolescent and adult males, 2) preferential allocation of food to children during the pre-harvest period, 3) seasonal reduction of activity levels and the year-round use of children for many productive activities, and 4) seasonal changes in meal patterns that minimize post-prandial energy loss during periods of stress. Evaluation of similar data from other anthropological populations underscores the diversity of responses to seasonal change in food availability. Moreover, these data indicate that the protection of children from seasonal energy stress is more common than previously thought. Variation in adaptive responses to food stress appears to be dependent upon 1) the nature of the subsistence economy, 2) the relative contributions of children and adults to household production, and 3) the demographic structure of the population.

Adolescent↗

Collection of survey data on contraception: an evaluation of an experiment in Peru.

The objective of this analysis is to compare two different approaches to the collection of information on contraceptive use. The data for this comparison are derived from the 1986 Demographic and Health Surveys (DHS) in Peru. Approximately 7,500 women were interviewed with the standard DHS questionnaire, whereas about 5,000 women received an "experimental questionnaire." The major difference between the questionnaires is the inclusion of a six-year monthly calendar in the experimental questionnaire that records pregnancies, contraceptive use, and postpartum information, in contrast to the more common tabular format of the standard questionnaire. The analysis demonstrates that although reports of contraceptive knowledge, ever-use, and current use are relatively robust to the variations in questionnaire design, estimates of past use are dependent on the survey instrument. Several different comparisons indicate that reporting of information on contraceptive histories in the experimental questionnaire is superior to that in the standard one.

Contraception Behavior↗

[A focus of Huntington's chorea in Peru].

Since 1970, 91 patients with Huntington's chorea have been identified in Peru, the majority of them, 42 cases, living in Cañete, a valley 140 km from Lima. The precise origin of the disease is unknown, but these patients are mostly half-bred from a mixture of White and Indian rather than from a mixture of Chinese, Japanese or Black.

Female↗

Paediatric campylobacter diarrhoea from household exposure to live chickens in Lima, Peru.

Although Campylobacter jejuni is a frequent enteropathogen in cases of paediatric diarrhoea in developing countries, its route of transmission is not well understood. An age-matched, case-control study of children with C. jejuni diarrhoea was therefore carried out in Lima, Peru, from January 1983 to April 1986 to identify the risk factors and vehicles of transmissions. As cases, 104 children less than 3 years of age were selected and compared with controls of the same age with non-gastrointestinal illnesses. Household exposure to live chickens was an important risk factor (odds ratio, 11; after adjusting for socioeconomic and environmental variables). Subjects in index households had a higher frequency of infection than those in control households, and infected young children were more likely to be ill than older children or adults, suggesting that immunity may be acquired from natural infection. The risk factors identified suggest that direct contact with the faeces of C. jejuni-infected chickens in the household environment was largely responsible for transmission of the organism to susceptible infants.

Animals↗

Basic elements for a national comprehensive plan for drug abuse control in Peru.

The first part of the article describes the nature and extent of drug abuse in Peru, with particular reference to the illicit cultivation of the coca plant and the national responses to these problems. It is estimated that between 150,000 and 200,000 hectares are under illicit coca plant cultivation, although less than 18,000 hectares are sufficient for meeting the legitimate needs for this plant in the country. It was estimated that 1.3 million children and youth were at risk of drug abuse in 1985. Both the problems and national responses are analysed in the context of historical and current developments that have influenced Peruvian drug abuse control policy, as well as in terms of the adequacy of programmes carried out within the social sectors involved in such control. The second part of the article summarizes the salient points extracted from the new national comprehensive plan for drug abuse control, which is intended to achieve a maximum reduction in drug abuse concurrently with the elimination of drug trafficking and the eradication of illicit coca plant cultivation in the country. The plan clearly defines the objectives, the strategies and the division of responsibilities in its implementation, involving the following four major sectors of activity: prevention, treatment and rehabilitation; control and monitoring of substances used for legitimate purposes; suppression of the illicit drug traffic; and the eradication of illicit coca plant growing together with the promotion of agricultural, agro-industrial and forestial development. It is pointed out that the whole nation needs to be mobilized in the implementation of the plan in order to achieve its objectives fully.

Coca↗

Socioeconomic conditions, food habits and formulated food programs in the Pueblos Jóvenes of Lima, Peru.

The present article examines attempts to develop and introduce formulated foods, or mixes, to low-income populations in Lima, Peru's Pueblos Jóvenes (squatter settlements). It discusses how socioeconomic conditions, dietary patterns, and economic pressures often mitigate against consumer acceptance. An alternative approach which stresses a prediagnostic study of clients' needs and careful monitoring of product development with consumer input is suggested.

Adolescent↗

Pterygium in Lima, Peru.

A survey of the prevalence of pterygium was performed, and a random proportional sampling was taken of 367 patients in four hospitals in Lima, Peru. An overall incidence of 31.06% was found, with a statistically significant increase in prevalence with regard to age. No statistically significant differences with regard to sex or occupation were found. Although incidence of pterygium was higher in men and in outdoor workers, these factors were not statistically significant.

Adolescent↗

[Prevalence of lysotype No. 3 of Salmonella paratyphi A in Peru].

Sixty-nine S. paratyphi A strains isolated from Peru were studied with the aid of the phage-typing system of Banker. 55 strains (79.7%) showed specific lytic reactions of the phage-type no 3 and 12 strains (17.3%) those of the phage-type no 1; one strain was atypical and another untypable. All of these strains were susceptible to ampicillin, chloramphenicol, streptomycin, tetracycline and trimethoprim. These results are compared with the data of the scientific literature on the worldwide distribution of the S. paratyphi A phage-types.

Humans↗

The nutritional quality of Scenedesmus acutus in a semi-industrial plant in Peru.

The nutritional quality of the flour of the micro-algae Scenedesmus acutus produced in a semi-industrial pilot plant at Sausal, Peru has been tested. The protein content varies between 47.4% and 66.6%. The PER was 2.63 = 0.15 (Casein 3.00 = 0.11), true digestibility 83.4 (Casein 92.4) and BV 60.9 (Casein 73.4). The protein quality did not increase by amino acid supplementation. The 12-week feeding test with micro-algae led to no abnormalities of the weight development, blood parameters, weights of organs and histological datas in the test animals. Further feeding trials and clinical examination on human subjects are recommended before approvement for use in human diet.

Amino Acids↗

Eimeria from bats of the world: a new species in Tomopeas ravus from Peru.

Two of 17 (12%) crevice bats, Tomopeas ravus (Chiroptera: Vespertilionidae), from Peru had coccidian oocysts in their feces when examined. Sporulated oocysts of Eimeria tomopea n. sp. are ellipsoid to subspheroid, 30.6 X 24.6 (26-34 X 20-28) micron with ovoid sporocysts 13.9 X 9.0 (12-15 X 8-10) micron. A micropyle and substieda body are absent, but polar bodies, oocyst and sporocyst residua, and small, indistinct Stieda bodies are present. The oocyst wall is thick, approximately equal to 1.5 micron and consists of 2 layers, the outermost being rough and mammillated. This is only the 13th eimerian to be described from bats worldwide. The currently recognized species of Eimeria are listed, and a possible New World-Old World phyletic split within the genus is described.

Animals↗

Description of redia and cercaria of Paragonimus peruvianus from experimentally infected Aroapyrgus colombiensis of Condebamba Valley, Peru.

Although no natural infections with lung flukes were encountered in the hydrobioid snail Aroapyrgus colombiensis from streams in the Condebamba Valley, Peru, laboratory-bred snails were readily susceptible to infection with miracidia of Paragonimus peruvianus. The redia and cercaria are described for the first time for those of neotropical lung flukes. Cercariae inside rediae did not have a stylet and development was apparently completed outside the rediae in snail tissues. The microcercous xiphidiocercaria had 2 groups of gland cells on each side; the outer consisted of 5 cells and the inner of 3 cells, all with ducts opening at the stylet. The excretory bladder was large, often triangular, was thick-walled, and of 1 layer of cuboidal cells. The redia lacked procrusculi and had a short intestine which was slightly longer than the pharynx.

Digestive System↗

[Classification of Leptospira isolated in Peru].

Antigenic properties of 23 leptospira cultures isolated in Peru were studied by immunological absorption. Two new individual leptospira serovars were classified as huanuco with a reference strain M-4, representing a new Huanuco serological group, and san-martini with a reference strain CT-63 belonging to the Hebdomadis serological group. Besides for the first time in the American part of the world serovar budapest belonging to Icterohaemorrhagiae serological group was recorded; also the first finding of serovar pyrogenes of the pyrogenes serological group was certified.

Animals↗