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Results for “HORSE DISEASES”

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At least 541 records · Page 30Linked to original sources
PubMed1984

Navicular bone disease: results of treatment using egg-bar shoeing technique.

Although the diagnostic criteria of navicular disease are generally accepted in practice, their limitations are recognised. However, the authors believe that navicular disease per se is reversible and that only secondary changes like adhesions to the deep flexor tendon or spur formations are irreversible. This hypothesis is supported by the results presented of the effect of the application of an egg-bar shoe, which caused permanent cessation of signs of navicular disease in more than 50 per cent of treated cases. The egg-bar shoeing technique can be usefully applied in practice.

Animals↗
PubMed1986

Incidence, diagnosis and treatment of postoperative complications in colic cases.

A survey of 259 surgical colic cases revealed that over 50 per cent of fatalities occurred in the postoperative period. Postoperative ileus and circulatory/endotoxaemic shock accounted for 70 per cent of these deaths. Other less important complications were salmonellosis, long bone fracture, adhesions, haemorrhage, laminitis, wound infection and ischaemic muscle damage. Close monitoring of postoperative progress is necessary to enable early diagnosis and treatment. Recent developments in understanding of the pathophysiology of endotoxic shock and ileus may lead to more successful treatment regimes. The possibilities include the use of cyclooxygenase inhibitors, anti-endotoxin hyperimmune serum and dopamine antagonists.

Animals↗
PubMed1988

Exploratory celiotomy for gastrointestinal disease in neonatal foals: a review of 20 cases.

The medical records of 20 neonatal foals in which exploratory celiotomies were performed for gastrointestinal disease were reviewed. In all 20 foals, persistent pain and/or progressive abdominal distension were the primary clinical findings influencing the decision to operate. However, ancilliary laboratory data were important to the proper medical management of these foals during anaesthesia and following surgery. Surgical diagnoses of the 20 foals included ileus (nine foals; 45 per cent), small colon obstruction (five foals; 25 per cent), large colon displacement (three foals; 15 per cent), small intestinal displacement (two foals; 10 per cent), and perforated gastric ulcer (one foal; 5 per cent). Seventeen foals were recovered from anaesthesia, 13 of these were discharged from the hospital, seven were alive six months or more following discharge. Sepsis was the cause of death in six of the 10 foals that died following recovery.

Animals↗
PubMed1995

Role of navicular bone shape in the pathogenesis of navicular disease: a radiological study.

From progeny lists of 30 Dutch Warmblood sires, 586 3-year-old females by these stallions were randomly selected, each progeny group aimed at 20 animals for statistical reasons. The front feet of the sires and female progeny were examined radiographically using lateromedial and dorsopalmar upright pedal projections. The radiological features associated with navicular disease were classified 0-4 using a standardised classification, grades 3 and 4 representing the more severe changes. The shape of the proximal articular border of the navicular bone outline on the dorsopalmar view was classified 1-4; 1=concave; 2=undulating; 3=straight; 4=convex. A significant shape-grade association was found, the highest grades 3 and 4 incidence demonstrated by shape 4. In shapes 1 and 2, navicular bones grades 3 and 4 features were mainly characterised by inverted flask-shaped channels. In shape 3, navicular bones grades 3 and 4 were dominated by enthesiophytes. These findings indicate an apparent shape predisposition to radiological changes associated with navicular disease. The shape of the navicular bone in the offspring was on average the same as the sire, indicating an hereditary element in navicular bone shape.

Animals↗
PubMed1997

Genetic markers in standardbred trotters susceptible to the rhabdomyolysis syndrome.

The equine rhabdomyolysis syndrome (RHA) is believed to be multifactorial in origin; and could be caused by an interaction between genetic and environmental factors. In order to analyse its genetic background an association study was undertaken. Two sample groups of Standardbreds (Stb) which had suffered from RHA were compared to the total population of Swedish Standardbred trotters using recorded polymorphic genetic markers. The results showed that gene frequencies for several markers in the RHA groups differed significantly from those estimated for the total population. A rhabdomyolysis risk group could be characterised using 4 or 5 genetic marker loci.

Alleles↗
PubMed2005

Enzyme-linked immunosorbent assays for detection of equine antibodies specific to Sarcocystis neurona surface antigens.

Sarcocystis neurona is the primary causative agent of equine protozoal myeloencephalitis (EPM), a common neurologic disease of horses in the Americas. We have developed a set of enzyme-linked immunosorbent assays (ELISAs) based on the four major surface antigens of S. neurona (SnSAGs) to analyze the equine antibody response to S. neurona. The SnSAG ELISAs were optimized and standardized with a sample set of 36 equine sera that had been characterized by Western blotting against total S. neurona parasite antigen, the current gold standard for S. neurona serology. The recombinant SnSAG2 (rSnSAG2) ELISA showed the highest sensitivity and specificity at 95.5% and 92.9%, respectively. In contrast, only 68.2% sensitivity and 71.4% specificity were achieved with the rSnSAG1 ELISA, indicating that this antigen may not be a reliable serological marker for analyzing antibodies against S. neurona in horses. Importantly, the ELISA antigens did not show cross-reactivity with antisera to Sarcocystis fayeri or Neospora hughesi, two other equine parasites. The accuracy and reliability exhibited by the SnSAG ELISAs suggest that these assays will be valuable tools for examining the equine immune response against S. neurona infection, which may help in understanding the pathobiology of this accidental parasite-host interaction. Moreover, with modification and further investigation, the SnSAG ELISAs have potential for use as immunodiagnostic tests to aid in the identification of horses affected by EPM.

Animals↗