[Serum enzyme activities and various blood biochemical constituents in subacute tetrachloro-1,1,1,2 ethane poisoning in the rabbit].
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Bentonite particles sensitized with concentrated human Old Tuberculin were used for detection of circulating antibodies to M. tuberculosis in human sera.There was no sharp distinction between the titres of patients with active and inactive tuberculosis, but progressively higher antibody titres accompanied increased severity of infection. The sera of 95.3% of the patients studied had a titre of 1:8 or higher. This level was considered to be the minimal significant titre indicative of the presence of metabolically active bacilli in old and new lesions. Tuberculin-negative controls and syphilitic sera were negative. A common zone of incidence in the 1:8-1:32 range was found where differentiation between tuberculin-positive healthy people and patients with tuberculosis was not possible; however, titres of 1:64 or more were found only in tuberculous patients. The antibody under study is heat-labile.
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The isolation and purification of split-products from tetanus toxin after freezing is reported. Antigenically defective and non-defective fragments exhibiting reduced molecular weights with respect to that of intact toxin were investigated as to their biological and immunological properties. The results obtained are discussed in relation to other data from the literature.
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The WR, Kline and VDRL reactions were compared in 496 cases of syphilis. The VDRL was significantly more sensitive than both WR and Kline.