Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “FIBROMA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 541 records · Page 30Linked to original sources
PubMed1988

Desmoplastic fibroma. A case report.

A desmoplastic fibroma occurring in the distal forearm of a 14-year-old black boy is described and the historical background of the tumour together with an outline of the disease emphasizes the differential diagnosis between this condition and other fibrous lesions of soft tissue and bone. The clinical and radiological features as well as the treatment of desmoplastic fibroma are discussed. It is believed that this is the first such patient reported in Africa.

Adolescent↗
PubMedDate not supplied

[Non ossifying fibroma with vertebral localization. Clinical case].

A case of non ossifying fibroma of a vertebral body causing a severe spinal cord compression is reported. A review of the literature shows that in the group of benign neoplasms of bone, non ossifying fibroma is uncommon and that its vertebral location is quite rare. The Authors discuss about the clinical, radiological and pathological features of these lesions which may be diagnostically confusing.

Adult↗
PubMed1988

Desmoplastic fibroma of the axis. A case report.

Desmoplastic fibroma of the bone appears in a wide variety of bones but rarely involves the spine. A 24-year-old male with desmoplastic fibroma of the axis treated by complete resection and posterior spinal fusion is reported. There was no recurrence of the tumor three years after surgery. Complete resection and reconstructive surgery for spinal instability are recommended for this benign spinal tumor.

Adult↗
PubMed1987

Urinary bladder fibromas in dogs: 51 cases (1981-1985).

Between Jan 1, 1981, and June 30, 1985, fibromas were diagnosed in tissues removed from the urinary bladders of 51 dogs. Hematuria, the most common clinical sign, was associated with the fibromas in 47 of 50 cases. Most dogs responded well to surgical excision of the neoplasms, with rapid resolution of the hematuria followed by long periods without abnormal clinical signs. Three dogs were euthanatized because of continuing or recurrent clinical problems, which included bladder dysfunction. One dog required continuing medication with antibiotics and corticosteroids to control hematuria.

Animals↗
PubMed1985

[Myocardial fibroma. Apropos of a case followed for 11 years].

A case of myocardial fibroma of the left ventricle is described in a young girl. The association of recurrent ventricular tachycardia and radiological deformation of the cardiac silhouette suggested the diagnosis and it was confirmed by myocardial scintigraphy, echocardiography and coronary angiography. At surgery, the tumour was too extensive to be removed. After 11 years follow-up, control of the arrhythmias is satisfactory and there has been no apparent increase in the tumour size. A review of 116 cases in the literature confirms the poor prognosis of myocardial fibroma. The diagnosis was made at autopsy in 60 cases. The 56 remaining patients were operated. Total resection was possible in 37 cases and partial resection in 4 cases. The tumour could not be removed in 15 cases. Overall operative mortality was 35 p. 100 but the prognosis thereafter was good.

Adolescent↗
PubMed1985

Desmoplastic fibroma of the first metatarsal. A case report.

Desmoplastic fibroma is a benign but frequently aggressive tumor of bone. A 27-year-old man was treated for this lesion in the first metatarsal. The lesion recurred, extending into the medial cuneiform necessitating ray resection. The similar clinical and histologic findings of this tumor and other tumors, both benign and malignant, makes familiarity with the character of desmoplastic fibroma essential for proper treatment.

Adult↗
PubMed1977

Ossifying fibroma of the occipital bone.

A rare ossifying fibroma in the occipital bone is described, and the available literature reviewed. The rapid growth seen in this case was remarkable and led us to believe this was a malignant osteogenic tumor. Full knowledge and the correct diagnosis of ossifying fibroma should have prevented an unnecessarily extensive operation for this benign lesion.

Child↗
PubMed1985

Light and electron microscopic comparisons of cutaneous fibromas in white-tailed and mule deer.

Cutaneous fibromas of white-tailed deer (Odocoileus virginianus), when compared with normal skin of the same species, had a thinner basement membrane; thickened stratum spinosum with numerous melanocytes, desmosomes, polyribosomes, and tonofilaments; focal hyperplasia of the stratum granulosum containing numerous large, electron-dense keratohyalin granules with irregular borders and containing occasional cells with diffuse intranuclear virus particles; and a moderately thickened stratum corneum with (although rarely) small crystalline arrays of virus particles. Normal mule deer (Odocoileus hemionus) skin was structurally similar to that of the white-tailed deer. Mule deer fibromas were similar to those in white-tailed deer, except for diffuse thickening of the stratum granulosum (the cells of which contained large keratohyalin granules of various electron densities with occasional composite granules) and except for a markedly thickened stratum corneum that contained numerous intranuclear viral inclusions. In negatively stained homogenates of tumors from both deer species, viral particles resembled papillomaviruses.

Animals↗
PubMed1985

[Case of desmoplastic fibroma of the femur].

A rare case of femoral desmoplastic fibroma that provoked essential difficulties in diagnosis is described. Histological and electron microscopic examination allowed the differential diagnosis between fibrosarcoma and desmoplastic fibroma.

Adult↗
PubMed1979

[Nasopharyngeal fibroma (author's transl)].

The authors report 17 cases nasopharyngeal fibroma treated between 1966 and 1978. Half of the cases developed before the age of 16, the other half occurring between 16 and 28 years. Arteriography was performed in only 8 cases and embolisation in 4 cases with 2 vascular accidents. Surgery was performed in 16 cases (15 Rouge Denker, 1 paralatero nasal). Invasion of the pterygomaxillary fossa was invariably found at operation. Amongst the patients treated by surgery, there was only one local recurrence and reoperation was successful. Finally, one patient with a very large fibroma with invasion of the temporal fossa was successfully treated by radiotherapy at a dose of 4 000 R.

Adolescent↗
PubMed1983

Immunologic dysfunction during viral oncogenesis. I. Nonspecific immunosuppression caused by malignant rabbit fibroma virus.

Malignant rabbit fibroma virus (MV) is a potent oncogenic poxvirus that produces a rapidly progressive syndrome of disseminated myxosarcoma, immunosuppression, and fatal gram-negative infection. MV is probably a recombinant between Shope fibroma virus (SFV) and rabbit myxoma virus, and is capable of preventing or aborting the in vitro proliferative responses of rabbit lymphocytes to B and T lymphocyte mitogens. Proliferative responses to sheep erythrocytes (SRBC) are similarly affected, although MV does not alter ongoing antibody responses to SRBC. Splenic lymphocytes from MV tumor-bearing rabbits suppress antibody and proliferative responses to SRBC when added to lymphocytes from SRBC-primed rabbits. Finally, lysates of cultured splenic lymphocytes from rabbits given MV suppress both proliferative and antibody-forming responses to SRBC. When MV is removed from these lysates by UV inactivation or by centrifugation, the suppressive activity remains. We therefore conclude that MV induces immunologic unresponsiveness in rabbits by at least two mechanisms. First, a direct suppressive effect of added virus on in vitro lymphocyte proliferation is seen. There is no effect in this situation if an antibody response is already in progress. Second, spleen cells exposed to MV in vivo produce one or more soluble factors capable of suppressing both proliferative and antibody responses of normal lymphocytes.

Animals↗
PubMed1981

An immunohistologic study of Shope fibroma virus in rabbits: tumor rejection by cellular reaction in adults and progressive systemic reticuloendothelial infection in neonates.

The development of lesions in adult and neonatal New Zealand White rabbits following intradermal inoculation of Shope fibroma virus was studied by immunofluorescence for viral antigens. T-cells, and immunoglobulin. In adults a self-limiting local fibroxanthosarcomatous tumor was rejected within 10-12 days in association with a dense infiltration of T-cells. In neonates expanding skin lesions were associated with systemic presence of virus in the reticuloendothelial system. In surviving infected neonates, granulomas formed at the site of infection after 3 weeks. These reactions may have limited further dissemination of the virus. These results support the hypothesis that the progressive disease produced by Shope fibroma virus in neonatal rabbits may be due to the inability of the reticuloendothelial system to clear infectious virus.

Animals↗
PubMed1983

Ossifying fibroma of bone. Report of two cases.

Two cases are reported of a hitherto undescribed type of lesion for which the term "ossifying fibroma of bone" is suggested. The lesions occurred in children aged 12 and 13 years, and involved the tibia and the humerus. Histologically they consisted of fibrous tissue containing small, partly calcified spherules: in this respect they differ from the usual types of fibro-osseous lesion such as fibrous dysplasia and osteofibrous dysplasia. The term "ossifying fibroma" is proposed for this condition, although in the past it has been applied to other types of bone lesion.

Adolescent↗
PubMed1984

Juvenile nodular aponeurotic fibroma in the area of the knee joint.

A case of calcifying aponeurotic fibroma of the knee occurred in a 14-year-old boy. Review of the literature reveals that calcifying aponeurotic fibroma is an uncommon benign tumor with a tendency for local recurrence. It is manifested by a progressively growing mass involving fat, fascia, and aponeurosis. Chondroid tissue and calcification within the areas of proliferated spindle cells are the characteristic features of this lesion and differentiate it from the other forms of fibromatosis.

Adolescent↗
PubMed1984

Fibroma of tendon sheath. A light and electron-microscopic study of 6 cases.

The clinical picture, the light and electron microscopic appearance, and the histochemical findings are described in six cases of fibroma of tendon sheath. The ages at onset for the four men and two women range between 16 and 54 years. The lesions were well circumscribed, rounded or oval, and had a diameter of about 1 cm. Light-microscopically the lesions consisted of a dense fibrocollagenous tissue with a variable degree of collagenization and cellularity, the peripheral zone often being most cellular and containing slit-like vascular spaces. Electron-microscopically two main cell types were identified: myofibroblasts and fibroblasts, the former dominating in cellular areas, the latter dominating in collagenized areas. The histochemical analysis indicated the presence of sulphated glucosaminoglycans within the collagenous matrix. Immunoperoxidase staining for factor VIII RAG-related antigen gave prominence to the endothelium of capillary-like blood vessels. The differential diagnosis against giant cell tumor of tendon sheath is discussed. The observations indicate that fibroma of tendon sheath is a distinct entity of probable reactive, non-neoplastic nature.

Adolescent↗
PubMed1983

[Vascular cellular elements as the source of development of desmoid fibroma].

Electron microscopic radioautography was used to investigate DNA and RNA syntheses in desmoid fibroma pieces ablated at operation. The DNA precursor 3H-thymidine was discovered to be incorporated only into vascular wall cells. RNA synthesis was the most overt in endotheliocytes, pericytes and fibroblasts adjacent to the vessels. At a distance from the vessels the majority of the cells were in a state of destruction. Based on the data obtained the authors arrive at the conclusion that the proliferation of vascular wall cells gives rise to the development of desmoid fibroma providing for the replenishment of tumorous cells. The latter ones, while making the cycle of differentiation and specific function, move away from the vascular lumen and then get destroyed.

Autoradiography↗
PubMed1981

Deer fibroma: a review.

Fibromas are frequent cutaneous neoplasms of young deer of many species, characterized by proliferation of both epithelial and dermal cells. Virus particles, similar to those found in fibrous skin tumors of several wild and domestic species, have been identified in some species by electron microscopy. Attempted transmission of fibromas has not been uniformly successful using filtered preparations.

Age Factors↗