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Results for “Decanoates”

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At least 541 records · Page 30Linked to original sources
PubMed1975

Observations on the dose regime of fluphenazine decanoate in maintenance therapy ofschizophrenia.

An analysis of the drug regimes prescribed to two separate groups of unselected schizophrenic patients indicates certain trends of clinical importance. The results demonstrate a need for the adoption of a personalized dose regime. The scatter of dose regimes found effective is too great to recommend a standardized approach to the prescription of L.A.P. injections. Two other results of particular significance are that the dose of drug required to control symptoms can be gradually reduced in nearly half of patients,and that helpful trends in prescribing were identified that will help the clinician to abolish side-effects.

Adult↗
PubMed1987

Double-blind comparison of half-dose and standard-dose flupenthixol decanoate in the maintenance treatment of stabilised out-patients with schizophrenia.

A double-blind controlled trial of 50% dose reduction in maintenance treatment in stable out-patients with low BPRS scores and good social function shows a significantly higher relapse rate in the low-dose group at 12 months (P less than 0.05). After an interval of 24-36 months from dose reduction, 56-76% had experienced a relapse and 76-79% had resumed their former dosage. No clear advantage was shown for the lower dose in either a reduction of side-effects or improved social function, but a reduced prevalence or lower rate of symptom emergence for tardive dyskinesia was suggested.

Adult↗