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At least 541 records · Page 30Linked to original sources
PubMed1998

Inflammatory diseases of the central nervous system in dogs.

Inflammatory diseases of the central nervous system (CNS) are important causes of seizures in dogs. Specific diseases include canine distemper, rabies, cryptococcosis, coccidioidomycosis, toxoplasmosis, neosporosis, Rocky Mountain spotted fever, ehrlichiosis, granulomatous meningoencephalomyelitis, and pug dog encephalitis. Inflammatory disorders should be considered when a dog with seizures has persistent neurological deficits, suffers an onset of seizures at less than 1 or greater than 5 years of age, or exhibits signs of systemic illness. A thorough history, examination, and analysis of cerebrospinal fluid are important in the diagnosis of inflammatory diseases. However, even with extensive diagnostic testing, a specific etiology is identified in less than two thirds of dogs with inflammatory diseases of the CNS.

Animals↗
PubMed1990

Chronic lung disease in old dogs and cats.

Chronic bronchial disease constitutes a significant, yet underdiagnosed, cause of both chronic cough and episodic and acute-onset respiratory distress in mature dogs and cats. Untreated chronic bronchial disease is a debilitating, progressive respiratory syndrome that results in decreased exercise tolerance, inactivity, paroxysmal respiratory distress, airway collapse and even death. With proper medical treatment, however, the prognosis for the effective long term management of chronic bronchial disease, even in severe cases, can be good.

Aerosols↗
PubMed2003

A Leishmania infantum multi-component antigenic protein mixed with live BCG confers protection to dogs experimentally infected with L. infantum.

The capacity of a quimeric protein, formed by the genetic fusion of five antigenic determinants from four Leishmania proteins, formulated with BCG, to protect dogs against Leishmania infantum infection is described. The data showed that after i.v. administration of 500,000 parasites of the L. infantum M/CAN/ES/96/BCN150 strain, zymodeme MON-1, the animals became infected as suggested by the humoral response against the parasite antigens. All control unvaccinated dogs had parasites in the lymph nodes at day 150 post-infection. One of these unvaccinated infected dog was parasite negative at day 634 behaving, thus, as resistant. In contrast, only 50% of the immunized dogs had parasites in the lymph nodes at day 150 post-infection. Four of these dogs became parasite negative by day 634 post-infection. The control animals developed at various times during the follow-up period clinical symptoms associated with Leishmaniasis. The control diseased dogs developed also in the liver and spleen some of the abnormal histological features associated with natural visceral Leishmaniasis. The immunized dogs, however, were not only normal at the clinical but also at the anatomo-pathological level. A positive delayed type hypersensitivity (DTH) response was observed in nine of the immunized protected dogs. The data indicated that Q+BCG confers 90% protection against infection and at least 90% protection at the clinical level.

Animals↗
PubMed1989

[The occurrence and significance of Chlamydia psittaci and Coxiella burnetii in dogs and cats. A study of the literature].

With this review of the literature it is demonstrated that not only infections with Chl. psittaci and C. burnetii do occur in dogs and cats in the Federal Republic of Germany but also clinical diseases caused by these agents may occur. Especially in diseases with uncharacteristic symptoms both bacteria have to be taken into consideration as causative agents. Since both agents cause zoonotic infections a correct diagnosis is of special importance, especially if the owner of a diseased dog or cat or members of his family show signs of disease also. In cases of unidentified disease or of a rickettsial zoonosis identification of the causative agent must be tackled by cultural or serological investigation. Direct or cultural identification is often not possible so that serological techniques have to be applied. Besides established serological techniques sensitive enzyme immunoassays are useful tools for securing a diagnosis.

Animals↗
PubMed1994

Infiltrative lipoma in dogs: 16 cases (1981-1992).

Medical records of 15 dogs with infiltrative lipoma, 1 of which had 2 lesions, were reviewed. Median age of affected dogs was 6.0 years, and median weight was 30.5 kg. The ratio of females to males was 4:1. Eight of the dogs were Labrador Retrievers. In 8 dogs, the lesions had previously been excised. There was not any apparent site predilection. Excision was the only treatment in all 15 dogs, and follow-up information was available for all dogs. Two dogs, each of which had 1 tumor, were euthanatized immediately after surgery, because the tumor could not be completely excised. Of the remaining 14 tumors, 5 (36%) recurred. Median time to recurrence for these 5 tumors was 239 days (range, 96 to 487 days). By means of Kaplan-Meier analysis, the percentage of dogs disease free 1 year after surgery was calculated to be 67%.

Animals↗
PubMed1998

Evaluation of primary haemostasis in canine leishmaniasis.

Primary haemostasis was evaluated by measurements of bleeding time and platelet count in 26 dogs with leishmaniasis and 10 normal dogs. Bleeding time was significantly (P = 0.02) longer in the infected dogs than in the control group, and in infected dogs with creatinine concentrations > 1.5 mg/dl than in infected dogs with normal creatinine levels. There was a significant linear regression between the concentration of creatinine and bleeding time (P = 0.02) although the coefficient of determination was low (r2 = 0.194). There were no significant differences in platelet counts between the normal and diseased dogs, and there were no significant differences between male and female dogs in either group.

Animals↗
PubMed1992

[A clinico-histological study for the diagnosis and classification of spontaneous periodontal diseases in the dog].

Using standardized investigation methods periodontal parameters were proved for diagnostic application of spontaneous periodontal diseases in dogs. The diseases are classified in gingivitis simplex, g. granulomatosa, g. ulcerosa, g. hyperplastica, g. desquamativa, juvenile periodontitis, rapidly progressive p. and chronic p. This proposal can be used for further investigations in experimental dentistry and for therapeutic purposes in veterinary dentistry.

Animals↗
PubMedDate not supplied

Auscultation in mild mitral regurgitation in dogs: observer variation, effects of physical maneuvers, and agreement with color Doppler echocardiography and phonocardiography.

Observer variation in diagnosing mild mitral regurgitation in dogs by cardiac auscultation was assessed by having 6 veterinarians with different levels of experience examine 57 Cavalier King Charles Spaniels. Comparisons with color Doppler echocardiography and phonocardiography were made, and the effects of 2 physical maneuvers on the auscultatory findings were evaluated. Using mildly diseased dogs, interobserver agreement in diagnosing the presence or absence of left-sided murmurs ranged from 63% to 88%. The agreement with phonocardiography (range, 53-91%) increased with the amount of observer experience. The 2 most experienced observers could discern soft ejection murmurs from regurgitant murmurs and were able to diagnose 89% of the dogs with regurgitant jets larger than 30% of the left atrial area. In general, less experienced observers diagnosed most jets larger than 50%. In many dogs with small jets, no murmur was found by auscultation and phonocardiography. The audibility of mild regurgitation was significantly reduced in dogs that were difficult to auscultate. Early systolic murmurs were typical of mild regurgitation, whereas holosystolic murmurs typified severe regurgitation. In a few dogs, late systolic murmurs alternated with holosystolic murmurs. Systolic clicks were found phonocardiographically in 18 dogs with mild to moderate regurgitation, but the audibility apparently was low. In many mildly affected dogs, physical maneuvers increased murmur intensity. Thus, some form of dynamic auscultation might facilitate the diagnosis of mild regurgitation. Auscultatory findings in mild regurgitation appear to depend on observer experience, circulatory status, and how difficult the dog is to auscultate.

Animals↗
PubMed1985

Retrovirus-like particles associated with myeloproliferative disease in the dog.

A case of granulocytic myeloproliferative disease with hypercalcaemia of malignancy in a 6-year-old Golden Retriever dog is described. Numerous retrovirus-like budding particles were observed at the cell surface of the neoplastic granulocytes, suggesting the presence of a new oncogenic virus. Several attempts by other workers to demonstrate the presence of an oncogenic retrovirus in canine lymphosarcoma have produced minimal results. This study suggests that non-lymphoid canine myeloproliferative disorders warrant further investigation.

Animals↗