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[Evoked response audiometry in circulatory disorders in the brainstem (author's transl)].

In the case of retrocochlear lesions evoked potentials from different stages of the auditory pathway were recorded. Four Patients with nearly normal hearing threshold and normal cortical potentials show reduced medium latency potentials show reduced medium latency potentials due to circulatory dysfunction in the brainstem. Desynchronisation effects on the brainstem level are completely compensated in the cortex. The damage of the auditory pathway could not be found by X-ray or other usual clinical methods. In the two cases described improvement under medical treatment can be demonstrated.

Audiometry↗

Clinical status of evoked response audiometry.

In the past decade there has been a widespread renewal of interest in the clinical utilization of electroencephalic responses evoked by auditory stimulation. In particular, there has been considerable research conducted on the brain stem response, the frequency following response, and the middle latency response. An overview discussion of some of the latest findings from recent and ongoing investigations is presented. Discussion is centered initially on current ideas, findings, and controversies regarding the origins or site of generation of these responses. Clinical application of the responses is discussed from two perspectives, audiologic applications and neurologic applications. Essential parameters for evoking, recording and analyzing clinically these responses are summarized. Some of the problems resulting from a lack of standardized clinical testing protocols are also mentioned. Key findings from recent clinical studies of some investigators are cited. Also recent data concerning the developmental aspects of the responses on clinical testing are included. Finally, some directions for future research on these responses are discussed. One of the latest techniques for recording and analyzing the responses and its implications for site of lesion neurologic testing are described.

Acoustic Stimulation↗

[Electrocochleography and phase audiometry in diagnosis of Meniere disease].

The diagnosis of Menière's disease is uncertain when the typical symptoms do not occur completely and definitely. A reliable finding of an endolymphatic hydrops (EH) is the base for a correct prognosis and therapy. Electrocochleography is a proven diagnostic procedure but requires a lot of time and of technical know-how. The mobility of cochlear partition can be tested by low-frequency masking (LFM) recording the phase dependent subjective masked threshold of a short test tone. We performed electrocochleography and LFM in 29 patients with suspected Menière's disease at the same day. Both tests pointed at an EH in 62%, and in 24% the results showed correspondent negative results. In 14% the results were inconsistent. Both methods also showed in 59% of the contralateral ears without symptomatic signs the indication of an EH. Considering the good conformity of both tests the easier LFM can be recommended for detection of EH.

Adolescent↗

["Audio 4": a simple and quick speech audiometry test for moderate hearing loss screening in four-year-old children].

UNLABELLED: The need for repeated auditory screening throughout early childhood faces the obstacle of the lack of objective validated material. OBJECTIVES: The goal of this two-year prospective study was to create and validate frequency-based word/picture lists appropriate for four-year-olds. Words were chosen not on the basis of the acoustic frequency of phoneme production, but on frequencies corresponding to their optimal recognition. Responses thus were to predict pure-tone threshold curves. MATERIAL AND METHODS: First of all, the linguistics laboratory created lists. Next, we proceeded to validate the form of the test: this involved verifying that the words selected on the basis of their frequency characteristics were common and well-known to children of this age. During the first year of the study, the picture boards were tested in a hospital otolaryngology service (66 children) and in a public health service (500 children) and corrected. RESULTS: All of the words and pictures were known during the next year by 5088 children. The second step was the audiometric validation of the test in a paediatric otolaryngology service. We compared classification of normal and impaired ears according to tonal audiograms and according to "Audio 4": 360 children were tested. Results were the following ones: Se: 0.81, Sp: 0.96, PPV: 0.91, NPV: 0.93. "Audio 4" therefore allows for prediction of pure-tone curves. CONCLUSION: This gives us hope that, directly interpretable by physicians, Audio 4, a rapid test which is attractive to children, will be used in diagnostic paediatric examinations whenever necessary.

Age Factors↗

A controlled study of the reliability of pure tone audiometry for the detection of gentamicin auditory toxicity.

Hearing changes in patients treated with gentamicin have been prospectively investigated. A group of patients who had a similar spectrum of clinical conditions but did not receive gentamicin have been studied as a control group. The audiometric technique was first validated by recording audiograms from healthy volunteers, once in an anechoic chamber and twice in a ward. It was concluded that changes in threshold less than 20 db. should not be regarded as significant when measured in a ward. In the gentamicin-treated group an initial audiogram was not a reliable measure of the patients' normal hearing because of the influence of their clinical condition. Twenty-one of the control patients were elective admissions to hospital and had their hearing first tested when they were clinically well. There was a 24 per cent incidence of unexplained hearing abnormalities--similar to the incidence of hearing loss in the gentamicin-treated group at follow-up. It was concluded that aminoglycoside auditory toxicity should not be assessed retrospectively. The incidence of hearing changes in the control and gentamicin-treated groups were similar. Possible causes of hearing loss in surgical patients are discussed and recommendations are made for the conduct of future studies of drug-induced auditory toxicity.

Adult↗

Dehiscence of bone overlying the superior semicircular canal as a cause of an air-bone gap on audiometry: a case study.

Dehiscence of bone overlying the superior semicircular canal can result in a syndrome of vertigo and oscillopsia induced by loud noises or by maneuvers that change middle ear or intracranial pressure. Patients with this disorder can also experience a heightened sensitivity to bone-conducted sounds in the presence of normal middle ear function. High-resolution CT scans of the temporal bones demonstrate the dehiscence. The authors describe a patient with bilateral superior canal dehiscence who had bilateral low-frequency conductive hearing loss, normal middle ear function, intact acoustic reflexes, and intact vestibular-evoked myogenic potentials. These findings would not be expected on the basis of a middle ear cause of the conductive hearing loss. A high-resolution CT scan of the temporal bones in this patient revealed bilateral superior canal dehiscence. Normal acoustic immittance findings in the presence of conductive hearing loss should alert clinicians to the possibility of inner ear cause of an air-bone gap due to superior canal dehiscence.

Audiometry↗